• 基本信息
    导师姓名: 刘智多 学科代码: 100100
    性别: 学科名称: 基础医学
    培养单位: 基础医学院 三级学科
    导师类型: 博士生导师 专业领域名称:
    联系方式: 021-63846590-776749 专业领域代码:
    邮编: 200025 邮箱地址: zhiduo.liu@shsmu.edu.cn
  • 研究方向 (点击浏览详细信息)
  • 社会任职
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    31870871CCR4控制调节性T细胞的空间分布及其对自身免疫性疾病的作用国家自然科学基金委员会 2019-01~2022-12 60万元  课题负责人
    1710000261海外高层次人才项目上海市教育委员会 2017-09~2020-08 100万元  课题负责人
    17PJ1408300骨髓中免疫前体细胞发育的微环境上海市科学技术委员会 2017-07~2019-06 20万元  课题负责人
    17ZR1425000骨髓里记忆性T细胞所处的微环境的研究上海市科学技术委员会 2017-05~2020-04 20万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Yu X, Lao Y, Teng XL, Li S, Zhou Y, Wang F, Guo X, Deng S, Chang Y, Wu X,, Chen L, Lu LM, Cheng J, Li B, Su B, Jiang J, Li HB, Huang C, Yi J, Zou Q.   SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation.  Nature Communications.  2018  9(1):3157-3167. 
    Yu X, Teng XL, Wang F, Zheng Y, Qu G, Zhou Y, Hu Z, Wu Z, Chang Y, Chen L, Li HB, Su B, Lu L,, Sun SC, Zou Q.  Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome.  Journal of Experimental Medicine.  2018  215(9):2463-2476. 
    Oyler-Yaniv A, Oyler-Yaniv J, Whitlock BM,, Germain RN, Huse M, Altan-Bonnet G, Krichevsky O.  A Tunable Diffusion-Consumption Mechanism of Cytokine Propagation Enables Plasticity in Cell-to-Cell Communication in the Immune System.  Immunity.  2017  46(4):609-620. 
    Veres TZ, Kopcsányi T, van Panhuys N, Gerner MY,, Rantakari P, Dunkel J, Miyasaka M, Salmi M, Jalkanen S, Germain RN.  Allergen-Induced CD4+ T Cell Cytokine Production within Airway Mucosal Dendritic Cell-T Cell Clusters Drives the Local Recruitment of Myeloid Effector Cells.   Journal of Immunology.  2017  198(2):895-907. 
    , Gerner MY, Van Panhuys N, Levine AG, Rudensky AY, Germain RN.   Immune homeostasis enforced by co-localized effector and regulatory T cells.   Nature.  2015  528(7581):225-30. 
    Lo B, Zhang K, Lu W, Zheng L, Zhang Q, Kanellopoulou C, Zhang Y,, Fritz JM, Marsh R, Husami A, Kissell D, Nortman S, Chaturvedi V, Haines H, Young LR, Mo J, Filipovich AH, Bleesing JJ, Mustillo P, Stephens M, Rueda CM, Chougnet CA, Hoebe K, McElwee J, Hughes JD, Karakoc-Aydiner E, Matthews HF, Price S, Su HC, Rao VK, Lenardo MJ, Jordan MB.  Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy.   Science.  2015  349(6246):436-40. 
    Li Z, Zhang Y,, Wu X, Zheng Y, Tao Z, Mao K, Wang J, Lin G, Tian L, Ji Y, Qin M, Sun S, Zhu X, Sun B.  ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1).  Nature Immunology.  2011  12(2):178-85. 
    Yang XO, Angkasekwinai P, Zhu J, Peng J,, Nurieva R, Liu X, Chung Y, Chang SH, Sun B, Dong C.   Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment.  Nature Immunology.  2009  10(12):1260-6. 
    Bi E, Huang C, Hu Y, Wu X, Deng W, Lin G,, Tian L, Sun S, Mao K, Zou J, Zheng Y, Sun B.  Novel function of perforin in negatively regulating CD4(+) T cell activation by affecting calcium signaling.  Cell Research.  2009  19(7):816-27. 
    ,, Li Z#, Mao K, Zou J, Wang Y, Tao Z, Lin G, Tian L, Ji Y, Wu X, Zhu X, Sun S, Chen W, Xiang C, Sun B.  Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling.  Journal of Immunology.  2009  183(10):6320-9. 
    Xie D#,, Li Z, Ji Y, Chen J, Sun B.   Differential expression of neutrophilic granule proteins between Th1 and Th2 cells.  Acta Biochimica et Biophysica Sinica.  2007  39(1):67-72.