王艳
性 别：女
联系电话：
邮箱地址：wangyan@shsmu.edu.cn
培养单位：公共卫生学院
学科/专业
研究方向
科研项目
代表性论文
科研获奖
专利授权
环境污染健康风险评价与替代毒理学
2019-05~2022-04，省级其他 ，基于类器官的外源化合物肝脏毒性替代测试体系的研究，课题负责人
2019-01~2022-12，省级其他 ，基于人源细胞的食品化学危害因子神经毒性体外高通量筛查技术研究，课题参与人
2018-01~2021-12，省自然科学基金 ，ER-EMT/CSC通路在大气细颗粒物有机组分致肺癌风险中的作用机制，课题负责人
2016-09~2021-06，科技部项目 ，中国人群重大出生缺陷的成因、机制和早期干预，课题参与人
2016-01~2019-12，省自然科学基金 ，基于人胚胎干细胞的环境内分泌干扰物低剂量暴露胚胎毒性评价模型的研究，课题负责人
2014-01~2016-12，省级其他 ，环境内分泌干扰物低剂量复合暴露胚胎干细胞发育毒性评价模型的研究，课题负责人
2014-01~2018-12，省级其他 ，环境内分泌干扰物对女性生殖功能的影响及分子机制，子课题负责人
2012-09~2015-09，省级其他 ，化学品发育毒性评价的小鼠胚胎干细胞替代模型的研究，课题负责人
2012-01~2014-12，科技部项目 ，基于重链抗体的食品中化学危害因子的快速检测技术的研发，课题负责人
Wang W, Zhou W, Wu S, Liang F, Li Y, Zhang J, Cui L, Feng Y, Wang Y.，Perfluoroalkyl substances exposure and risk of polycystic ovarian syndrome related infertility in Chinese women，Environ Pollut，2019，247:824-831
Luo F, Wei H, Guo H, Li Y, Feng Y, Bian Q, Wang Y，LncRNA MALAT1, an lncRNA acting via the miR-204/ZEB1 pathway, mediates the EMT induced by organic extract of PM2.5 in lung bronchial epithelial cells，Am J Physiol Lung Cell Mol Physiol，2019，317(1):L87-L98
Cheng W, Yang S, Liang F, Wang W, Zhou R, Li Y, Feng Y, Wang Y.，Low-dose exposure to triclosan disrupted osteogenic differentiation of mouse embryonic stemcells via BMP/ERK/Smad/Runx-2 signalling pathway，Food Chem Toxicol，2019，127:1-10
Li L, Ying Y, Zhang C, Wang W, Li Y, Feng Y, Liang J, Song H, Wang Y，Bisphenol A exposure and risk of thyroid nodules in Chinese women: A case-control study，Environ Int，2019，126:321-328
Wei H, Liang F, Cheng W, Zhou R, Wu X, Feng Y, Wang Y.，The mechanisms for lung cancer risk of PM2.5: Induction of epithelial-mesenchymal transition and cancer stem cell properties in human non-small cell lung cancer cells，Environ Toxicol，2017，32(11):2341-2351
Wei Hongying,Feng Yan,Liang Fan,Cheng Wei, Wu Xiaomeng,Zhou Ren, Wang Yan，Role of oxidative stress and DNA hydroxymethylation in the neurotoxicity of fine particulate matter，TOXICOLOGY，2017，380: 93-104
Ren Zhou, Wei Cheng, Yan Feng, Yan Wang，Interactions between three typical endocrine-disrupting chemicals (EDCs) in binary mixtures exposure on myocardial differentiation of mouse embryonic stem cell，Chemosphere ，2017，178:378-383
Wei Cheng,Ren Zhou, Fan liang, Hongying Wei, Yan Feng, Yan Wang ，Application of Mouse Embryonic Stem Cell Test to Detect Gender-Specific Effect of Chemicals: A Supplementary Tool for Embryotoxicity Prediction，Chem Res Toxicol，2016，29 (9) :1519-1533
Feng Y, Zeng W, Wang Y, Shen H, Wang Y，Long-term exposure to high levels of decabrominated diphenyl ether inhibits CD4 T-cell functions in C57Bl/6 mice，J Appl Toxicol，2016，36(9):1112-1119
Hongying Wei, Wei Cheng, Ren ZHou, Xiaomeng Wu, Yan Feng, Yan Wang，Redox/methylation mediated abnormal DNA methylation as regulators of ambient fine particulate matter-induced neurodevelopment related impairment in human neuronal cells，Sci. Rep.，2016，6:33402-33402
Cheng W, Zhou R, Feng Y, Wang Y，Mainstream smoke and sidestream smoke affect the cardiac differentiation of mouse embryonic stem cells discriminately，Toxicology，2016，357:1-10
G Meng，Z Nie，Y Feng，X Wu，Y Yin，Yan Wang，Typical Halogenated Persistent Organic Pollutants in Indoor Dust and the Associations with Childhood Asthma in Shanghai, China.，Environ Pollut.，2016，211:389-398
Meng G, Feng Y, Nie Z，X Wu，Y Yin，Yan Wang ，Internal Exposure Levels of Typical POPs and Their Associations with Childhood Asthma in Shanghai, China ，Environ Res. ，2016，146:125–135
Feng Y, Hu Q, Meng G, Wu X, Zeng W, Zhang X, Yu Y, Wang Y，Simulating long-term occupational exposure to decabrominated diphenyl ether using C57BL/6 mice: biodistribution and pathology.，Chemosphere，2015，128:118-124
Zeng W, Wang Y, Liu Z, Khanniche A, Hu Q, Feng Y, Ye W, Yang J, Wang S, Zhou L, Shen H, Wang Y，Long-term exposure to decabrominated diphenyl ether impairs CD8 T-cell function in adult mice，Cell Mol Immunol，2014，11(4):367-376
Cheng W, Yu Z, Feng L, Wang Y，Perfluorooctanesulfonate (PFOS)induced embryotoxicity and disruption of cardiogenesis，Toxicology in Vitro，2013，27(5):1503-1512