陈颖盈
性 别：女
联系电话：021-63846590-776443
邮箱地址：yingying.chen@shsmu.edu.cn
培养单位：基础医学院
学科/专业
研究方向
科研项目
代表性论文
科研获奖
专利授权
2025-12~2028-11，新发突发与重大传染病防控国家科技重大专项 ，暴露后预防性亚单位疫苗的顶层设计与概念验证，子课题负责人
2024-01~2026-12，国家自然科学基金委专项项目 ，BCG诱导固有免疫记忆屏障增强抗新冠病毒感染的分子机制，课题负责人
2023-04~2026-03，上海市科委2023自然基金面上项目 ，巨噬细胞驯化免疫增强抗病毒免疫应答的分子机制，课题负责人
2019-07~2022-06，上海市“科技创新行动计划”自然科学基金面上项目 ，结核分支杆菌脂蛋白Z参与抗结核感染的多效免疫学应答机制，课题负责人
2019-01~2022-12，上海市卫生和计划生育委员会临床研究面上项目 ，基于代谢组学的耐药结核患者化疗新方案的疗效评估指标体系建立和临床初步验证，课题负责人
2016-01~2018-12，国家自然科学基金青年基金项目 ，支链氨基酸调节抗结核多能T细胞免疫应答的模式及相关机制研究，课题负责人
Yong Li#, Cheng-cheng Yao#, Ping Ji, Hui-yu Wang, Shu-jun Wang, Ying Wang, Qi-jian Cheng*, Lu Xia*, Ying-ying Chen*，Plasma dynamic metabolomics during anti-tuberculosis treatment identifies an amino acid panel with diagnostic potential，LabMed Discovery，2025，2:100059
Xiaoxu Yang#, Lan Yao#, Xu-wei Gui#, Yangdian Lai, Ping Ji, Ying Wang, Yingying Chen*, Wei Sha，Immune profiles of immune checkpoint molecules on peripheral T cells in multidrug resistant-tuberculosis，International Journal of Infectious Diseases，2025，161:108085
Yunfei Li#, Junyao Lu#, Liheng He#, Chengxin Jiang, Yujie Bao, Ping Ji, Jie Xu*, Yingying Chen*, Ying Wang，Repeated Omicron infections overcome T cell immune imprinting to original SARS-CoV-2，Journal of Medical Virology，2025，97:e70264
Jiajia Lin#, Shiyu Bai#, Liheng He#, Ye Yang, Xiyue Li, Liulin Luo, Ying Wang, Ying-ying Chen*, Jinhong Qin, Yi Zhong*，Cytotoxic lymphocyte-monocyte complex reflects the dynamics of COVID-19 systemic immune response，The Journal of Infectious Diseases，2024，230(1):5-14
Yujie Bao#, Liheng He#, Benjie Miao#, Zhengrong Zhong#, Guanzhu Lu, Yupan Bai, Qiming Liang, Yunchao Ling, Ping Ji, Bing Su, Guo-ping Zhao, Hao Wu, Wenhong Zhang, Ying Wang*, Yingying Chen*, Jie Xu*，BBIBP-CorV vaccination accelerates anti-viral antibody responses in heterologous Omicron infection: A retrospective observation study in Shanghai，Vaccine，2023，41:3258-3265
Bo Gao#, Li-heng He#, Yu-jie Bao#, Ying-ying Chen#, Guan-zhu Lu, Yu Zhang, Yingjie Xu, Bing Su, Jie Xu*, Ying Wang*, Leng-Siew Yeap*，Repeated vaccination of inactivated SARS-CoV-2 vaccine dampens neutralizing antibodies against Omicron variants in breakthrough infection，Cell Research，2023，33:258–261
Dong Wei#, Yingying Chen#, Xiaoqi Yu, Yang-dian Lai, Wenxin Xu, Ping Ji, Zhitao Yang, Erzhen Chen, Xinxin Zhang*, Ying Wang*，Comparable antigen-specific T cell responses in vaccinees with diverse humoral immune responses after the primary and booster BBIBP-CorV vaccination，Emerging Microbes and Infections，2022，11(1):2474-2484
Yujie Bao#, Yun Ling#, Ying-Ying Chen#, Di Tian, Guo-Ping Zhao, Xiang-Hui Zhang, Hong Hang, Yu Li, Bing Su, Hong-Zhou Lu*, Jie Xu*, Ying Wang*，Dynamic anti-spike protein antibody profiles in COVID-19 patients，International Journal of Infectious Diseases，2021，103:540-548
I Kuan Sam#, Ying-ying Chen#, Jun Ma#, Shi-yuan Li#, Ruo-yan Ying, Lin-xian Li, Ping Ji, Shu-jun Wang, Jie Xu, Yu-jie Bao, Guo-ping Zhao, Hua-jun Zheng, Jin Wang*, Wei Sha*, Ying Wang*，TB-QUICK: CRISPR-Cas12b-assisted rapid and sensitive detection of Mycobacterium tuberculosis，Journal of Infection，2021，83(1):54-60
Yang-dian Lai#, Ying-ying Chen#, Ji-ping Sun#, Yun Ling, Jie Xu, Youqiong Ye, Lei Shen, Hong-zhou Lu*, Bing Su*, Ying Wang*， Immune profiles of a COVID-19 adolescent with mild symptoms and anti-viral antibody Deficiency，Fundamental Research，2021，1:117-123
Lingjie Luo#, Wenhua Liang#, Jianfeng Pang#, Gang Xu#, Yingying Chen#, Xinrong Guo, Xin Wang, Yi Zhao, Yangdian Lai, Yang Liu, Bin Li, Bing Su, Shuye Zhang, Michal Bniyash, Lei Shen, Lei Chen, Yun Ling, Ying Wang, Qiming Liang, Hongzhou Lu*, Zheng Zhang*, Feng Wang*，Dynamics of TCR repertoire and T cell function in COVID-19 convalescent individuals，Cell Discovery，2021，0.353472
Qing-Yuan Yang#, Yu-Tong Zhang#, Jia-Ni Xiao, Yu-Shuo Liang, Ping Ji, Shu-Jun Wang, Ying Wang*, Ying-Ying Chen*，Age-related immunoreactivity profiles to diverse mycobacterial antigens in BCG vaccinated Chinese population，Frontiers in Immunology，2021，11:608220
Ying Tian#, Chaoyang Lian#, Yingying Chen#, Dong Wei, Xinxin Zhang, Yun Ling*, Ying Wang*, Leng-Siew Yeap*，Sensitivity and specificity of SARS-CoV-2 S1 subunit in COVID-19 serology assays，Cell Discovery，2020，0.302083
Yingying Chen#, Jia-ni Xiao#, Yong Li#, Yang-jiong Xiao#, Yan-qing Xiong, Ying Liu, Shu-jun Wang, Ping Ji, Guo-ping Zhao, Hao Shen, Shui-hua Lu, Xiao-yong Fan*, Ying Wang*，Mycobacterial lipoprotein Z triggers efficient innate and adaptive immunity for protection against Mycobacterium tuberculosis infection，Frontiers in Immunology，2019，2.590278
Yuan-yong Liu#, Wei Sha#, Shi-qiang Xu, Xu-Wei Gui, Li-liang Xia, Ping Ji, Shu-jun Wang, Guo-ping Zhao, Xiao Zhang*, Yingying Chen*, Ying Wang，Identification of HLA-A2-restricted mycobacterial lipoprotein Z peptides recognized by T cells from patients with active tuberculosis infection，Frontiers in Microbiology，2018，2.549306
Jia-ni Xiao#, Yanqing Xiong#, Yingying Chen#, Yang-jiong Xiao, Ping Ji, Yong Li, Shu-jun Wang, Guo-ping Zhao, Qi-jian Cheng, Shui-hua Lu*, Ying Wang*，Determination of lipoprotein Z-specific IgA in tuberculosis and latent tuberculosis infection，Frontiers in Cellular and Infectious Microbiology，2017，0.635417
Yingying Chen#, Ouerdia Maskri#, Francoise Chaminade, Brigitte René, Jessica Benkaroun, Julien Godet, Yves Mely, Olivier Mauffret, Philippe Fossé*，Structural insights into the HIV-1 minus-strand strong-stop DNA，Journal of Biological Chemistry，2016，291(7): 3468-3482