毛燕飞
性 别：男
联系电话：
邮箱地址：maoyanfei1979@163.com
培养单位：新华医院
学科/专业
研究方向
科研项目
代表性论文
科研获奖
专利授权
脓毒症
围术期肺损伤的机制与防治研究
2023-01~2026-12，国家自然科学基金面上项目 ，PGC-1α/Nrf2-PINK1信号通路在呼吸机相关性肺损伤中的作用及甲状腺素对其调控机制的研究 ，课题负责人
2018-01~2021-12，国家自然科学基金面上项目 ，基于多组学数据整合探讨机械通气相关性肺损伤预警标志物的产生机制，课题负责人
2014-01~2017-12，国家自然科学基金面上项目 ，Renin-Angiotensin System在介导机械通气所致肺微血管内皮细胞功能障碍中的作用及其机制研究，课题负责人
2010-01~2012-12，国家自然科学基金青年项目 ，αvβ5整合素与RhoA/ROCK信号转导通路介导肠缺血再灌注诱发肺损伤的机制研究，课题负责人
2009-12~2011-12，上海市教委青年科研基金 ，NE及E通过TLR4加重内毒素诱发的肺损伤，课题负责人
Zhao G, Zhang J, Wu J, Sheng Y, Zhang Y, Chen X, Mao Y.，Spatiotemporally responsive hybrid hydrogels for sequential therapy and visualized monitoring of multidrug-resistant bacterial wound infections，Bioact Mater . ，2026，63:506-523
Siyuan Li,Lixia Li,Xiaohui Huang,Qin Xia,Liuyan Zhou,Bohan Zhang, Jingnan Xiong,Rongrong Ren,Aiying Chen,Gang Zhao,Yanfei Mao，Tailor-Engineered nano-diagnostic platform for polymyxin B monitoring and its biological application based on molecularly imprinted Sulphur-doping graphene quantum dot–derived，Chemical Engineering Journal，2025，509：161122
Hanqing Li, Haoni Yan, Jingnan Xiong, Yun Wang, Xianhao Wu, Decui Cheng, Deli Lin, Xin Li, Min Lu, Yanfei Mao，Neutrophil-mediated delivery of hybrid cross-species nanovesicles for treatment of bacterial infections， Nature communications ，2025，2025 Dec 22;16(1):11564.
Shuxian Duan, Hanqing Li, Fei Wang, Lixia Li, Huizhen Fan, Yingying Ma, Qiang Yu, Li Wei, Mei X. Wu, Yanfei Mao, Min Lu，An All-in-One Nano-Biomimetic Polyamidoamine Dendrimer Platform for Treatment of CRKP Pneumonia，Advanced Functional Materials，2024，2026-06-07
Hanqing Li，Shuxian Duan，Lixia Li，Gang Zhao，Li Wei，Bohan Zhang，Yingying Ma，Mei X Wu，Yanfei Mao，Min Lu ，Bio-Responsive Sliver Peroxide-Nanocarrier Serves as Broad-Spectrum Metallo-β-lactamase Inhibitor for Combating Severe Pneumonia，Adv Mater.，2024，e2310532.
Peng Ding，Rui Yang，Cheng Li， Hai-Long Fu ，Guang-Li Ren，Pei Wang，Dong-Yu Zheng，Wei Chen ，Li-Ye Yang，Yan-Fei Mao，Hong-Bin Yuan，Yong-Hua Li ，Fibroblast growth factor 21 attenuates ventilator-induced lung injury by inhibiting the NLRP3/caspase-1/GSDMD pyroptotic pathway，Crit Care ，2023，27(1):196
Bohan Zhang,Wenwen Dong,Zhixin Ma,Shuxian Duan,Ruina Han,Zhou Lv,Xinru Liu,Yanfei Mao，Hyperbaric oxygen improves depression-like behaviors in chronic stress model mice by remodeling gut microbiota and regulating host metabolism，CNS Neurosci Ther，2023，29(1):239-255.
Mao Y, Ma Z, Xu C, Lv Z, Dong W, Liu X.，Pathogenesis of ventilator-induced lung injury: metabolomics analysis of the lung and plasma.，Metabolomics.，2022，18(8):66.
Ruan Z, Ren R, Dong W, Ma J, Xu Z, Mao Y, Jiang L，Assessment of vocal cord movement by ultrasound in the ICU，Intensive Care Med，2018，44 (12): 2145-2152
C.H. Han,Z.B.Guan,P.X.Zhang, H.L.Fang,L.Li, H.M.Zhang,F.J. Zhou,Y.F. Mao,W.W.Liu，Oxidative stress induced necroptosis activation is involved in the pathogenesis of hyperoxic acute lung injury，Biochemical and Biophysical Research Communications，2018，495：2178-2183
Y.Li,K.Liu,Z.M.Kang,X.J.Sun,W.W.Liu,Y.F.Mao，Helium preconditioning protects against neonatal hypoxia–ischemia，Behavioural Brain Research，2016，300:31–37
Liu K, Mao YF, Zheng J, Peng ZY, Liu WW, Liu Y, Xu WG, Sun XJ, Jiang CL, Jiang L.，SC5b-9-Induced Pulmonary Microvascular Endothelial Hyperpermeability Participates in Ventilator-Induced Lung Injury，Cell Biochem Biophys.，2013，67(3):1421-1431.
Yan-Fei Mao, Yong-Qi Li, Lin Zong, Xin-Min You, Fu-Qing Lin,Lai Jiang，Methanol extract of Phellodendri cortex alleviates lipopolysaccharide-induced acute airway inflammation in mice，Immunopharmacol Immunotoxicol. ，2010，32(1):110-115
Mao YF, Liu XR, Liao XZ, Lv YH, Xu H, Deng XM, Yan SK, Xiong YC, Zhang WD. ，Blood serum profiling of the rat spinal nerve ligation model using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry.，Eur J Pharmacol，2009，615(1-3):61-65
Mao YF, Yan N, Xu H, Sun JH, Xiong YC, Deng XM，Edaravone, a free radical scavenger, is effective on neuropathic pain in rats.， Brain Res.，2009，1248:68-75