路丽明
性 别:女
联系电话:
邮箱地址:lulunew2003@163.com
培养单位:基础医学院
学科/专业
研究方向
科研项目
代表性论文
科研获奖
专利授权
免疫调节
2024-10~2026-12,名贵中药资源可持续利用能力建设项目 ,栝篓来源的中药天花粉蛋白及其生菜表达重组蛋白治疗炎症性肠病的应用探索,课题负责人
2022-09~2025-08,上海市科学技术委员会 ,中药天花粉蛋白作为干细胞来源新型冠状病毒疫苗高效能增强剂的可行性研究,课题负责人
2021-01~2024-12,国家自然科学基金项目 ,中药天花粉蛋白作为A群流脑疫苗免疫增效剂的应用基础研究,课题负责人
2021-01~2025-12,重点研发计划项目 ,人脐带间充质干细胞治疗视神经脊髓炎谱系疾病的临床研究,课题参与人
2020-08~2022-08,上海市卫生健康委员会 ,组蛋白去甲基化酶LSD1对天花粉蛋白诱导的CD8+Treg谱系维持的作用,课题负责人
2018-05~2021-04,上海市科学技术委员会 ,建立KRAS突变肺癌双人源化小鼠模型并用于临床患者药物治疗方案评估的探索,课题负责人
2017-07~2021-12,国家重点研发计划重点专项项目 ,单倍型相合移植(“北京方案”)后适应性免疫重建及调控机制,课题负责人
2017-01~2019-12,上海市教委 ,中药天花粉蛋白衍生肽通过Treg细胞延缓肺移植术后闭塞性细支气管炎综合症的可行性研究,课题负责人
2017-01~2020-12,国家自然科学基金,面上项目 ,Treg抑制同种异体肺移植慢性排斥的应用基础研究,课题负责人
2015-09~2017-08,上海市浦江人才计划(D类) ,中药天花粉蛋白来源的生物活性多肽治疗Th1细胞主宰疾病的药效及作用机理研究,课题负责人
2015-07~2018-09,上海市科委中药新药候选药物研究 ,Tk-PQ作为高效低毒免疫调节剂的成药性研究,课题负责人
2014-08~2017-09,上海市科委产学研项目 ,TIL细胞治疗肺癌的医学转化研究,课题负责人
2014-01~2017-12,国家自然科学基金,面上项目 ,CIITA通过NLR信号调控Th2应答的分子免疫学机制,课题负责人
2010-01~2012-12,国家自然基金,面上项目 ,IL-9(+)IL-10(+)T细胞与Th9的免疫生物学特性比较研究,课题负责人
2008-01~2010-12,国家自然基金委,面上项目 ,CIITA突变体功能性剔除MHC及作用机制的研究,课题负责人
Hu Y, Wu L, Qu S, Kong WT, Yu X, Xu J, Xu Z, He J, Wang C, Liu Z, Liming Lu, Ng LG, Blériot C, Su B, Ginhoux F, Li Z, Chakarov S,Temporal and spatial atlas of eosinophil specialization across tissues,Nat Immunol,2026,27(2):364-375
Anmin Ren, QianjunLiu, QianGan, Liming Lu, XinKaiQu,Associations of Inflammatory Markers and Coronary Heart Disease in Different Gender Groups in Cohort NHANES 2003-2018,Cardiol Res Pract,2026,2026:5555602
Feng Z, Li CS, Fu H, Jiang W, Zhang W, Huang Y, Huang Y, Tam TTKK, Li Y, Liu F, Liming Lu, Lee YL, Yeung WSB, Dougan G, Liu P,A Novel Human Cellular System for Studying Normal Aging and for Anti-Aging Discovery,Aging Cell,2026,25(2):e70352
Huizhuang Shan, Youping Zhang, Xinhua Xiao, Wenxuan Wu, Yingying Wang, Chujiao Zhu1, Wenhui Bai, Ziwei Zhang, Yuanhui Zhai, Li Yang, Yunzhao Wu, Hu Lei, Hanzhang Xu, Yanfei Luo, Liming Lu*, Yingli Wu*,USP7 sustains hematopoietic stem cell homeostasis partially via PU.1 stabilization,International Journal of Biological Sciences,2026,22(2): 1036-1052
Zhang D, Heng Y, Jin QY, Tang D, Zhu XK, Lu LM, Wu CP, Tao L,Prognostic significance of cytotoxic-T-lymphocytes to immunosuppressive lymphocytes ratio (CIL) in laryngeal squamous cell carcinoma,Cancer Immunol Immunother,2025,74(5):157
Zhang L, Lin L, Xiao B, Huang K, Liu J, Chen YL, Liming Lu, Zhang Z, Zhang L, Li J, Ho KT, Luo L, Huang SY, Li G,Eicosapentaenoic acid (EPA) reduced lipopolysaccharide-stimulated inflammatory response of RAW264.7 cells via the miR-125b-5p/CREB axis,Int J Biol Macromol,2025,310(Pt 4):143511
Liu JG, Yu L, Guo XL, He XM, Li M, Gao RY, Zhao BH, Li QY, Zhu WJ, Xu P, Gu XH, Chen YA, Yin XL, Shang Y, Guo ZH, Mao JH, Hu YX, Lu LM, Hua J, Zhang H, Li Y,Characterizing the immune landscape of tumor-infiltrating lymphocytes in non-small cell lung cancer,Genes Immun,2025,2025 May 5
6. Ng LG, Ballesteros I, Cassatella MA, Egeblad M, Fridlender ZG, Gabrilovich D, Gao Q, Granot Z, Grieshaber-Bouyer R, Grimes HL, Hedrick CC, Hidalgo A, Kaplan MJ, Kubes P, Ling GS, Liming Lu, Luo HR, Mayadas TN, Moutsopoulos NM, Ng M, Nigrovic PA, Ostuni R, Pittet MJ, Quail DF, Silvestre-Roig C, Soehnlein O, Udalova IA, Xue R, Zhang N, Kwok I,From complexity to consensus: A roadmap for neutrophil classification, Immunity,2025,58(8):1890-1903
Liu D, Wang X, Han Y, Wang J, Sun Y, Hou Y, Wu Q, Zeng C, Ding X, Chang Y, Hu J, Huang X, Liming Lu,A donor PD-1+CD8+ TSCM-like regulatory subset mobilized by G-CSF alleviates recipient acute graft-versus-host-disease,Signal Transduct Target Ther,2025,10(1):120
Lin H, Ma J, Heng Y, Zhu X, Jin Q, Ding X, Tao L, Liming Lu*,CD8+ T cells in patients with hypopharyngeal squamous cell carcinoma are susceptible to radiation-induced damage,Int J Cancer,2025,156(10):2010-2023
Yunbin Zhang, Xuping Ding, Qian Zhang, Cong Zeng, Hongzhuan Chen, Liming Lu,Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx,J Adv Res,2024,S2090-1232(24)00493-4
Zhou D, Xu W, Ding X, Guo H, Wang J, Zhao G, Zhang C, Zhang Z, Wang Z, Wang P, Lu L, Yuan M,Transient inhibition of neutrophil functions enhances the antitumor effect of intravenously delivered oncolytic vaccinia virus,Cancer Sci,2024,115(4):1129-1140
Yangyang Ji , Yu Heng, Xiaoke Zhu , Duo Zhang, Di Tang, Jian Zhou , Hanqing Lin , Jingyu Ma , Xuping Ding , Lei Tao , Liming Lu ,Increased tumor-infiltrating plasmacytoid dendritic cells express high levels of PD-L2 and affect CD8+ lymphocyte infiltration in human laryngeal squamous cell carcinoma,Translational Oncology,2024,45:101936.
Zhu X, Heng Y, Zhang D, Tang D, Zhou J, Lin H, Ma J, Ding X, Tao L, Li-Ming Lu,Prognostic significance and immune escape implication of tumor-infiltrating neutrophil plasticity in human head and neck squamous cell carcinoma,Hum Cell,2024,37(3):714-728
Ma J, Zhu X, Heng Y, Ding X, Tao L, Li-Ming Lu,Establishment and characterization of a novel hypopharyngeal squamous cell carcinoma cell line CZH1 with genetic abnormalities,Hum Cell,2024,37(2):546-559
Xiaoke Zhu, Yu Heng , Jingyu Ma, Duo Zhang , Di Tang , Yangyang Ji , Changding He , Hanqing Lin, Xuping Ding, Jian Zhou , Lei Tao , Liming Lu,Prolonged Survival of Neutrophils Induced by Tumor-Derived G-CSF/GM-CSF Promotes Immunosuppression and Progression in Laryngeal Squamous Cell Carcinoma, Adv Sci (Weinh),2024,24:e2400836
Lv QM, Lei HM, Wang SY, Zhang KR, Tang YB, Shen Y, Li-Ming Lu, Chen HZ, Zhu L,Cancer cell-autonomous cGAS-STING response confers drug resistance,Cell Chem Biol,2023,30(6):591-605
Heng Y,Zhu XK,Lin HQ,Ma JY,Ding XP,Zhang D,Tang D,Tao L,Lu LM,CD206+ tumor-associated macrophages interact with CD4+ tumor-infiltrating lymphocytes and predict adverse patient outcome in human laryngeal squamous cell carcinoma,Journal of Translational Medicine,2023,21(1):167
Jie Shu, Kefan Wang, Yuting Liu, Jie Zhang, Xuping Ding, Hanxiao Sun, Jiaoxiang Wu, Biao Huang, Ju Qiu, Huiming Sheng, Li-Ming Lu,Trichosanthin alleviates streptozotocin-induced type 1 diabetes mellitus in mice by regulating the balance between bone marrow-derived IL6+ and IL10+ MDSCs,Heliyo,2023,10(1):e22907
Yuting Liu,Kefan Wang,Shuofei Yang,Guanhua Xue,Liming Lu,Mulberry extract upregulates cholesterol efflux and inhibits p38 MAPK-NLRP Mediated inflammation in foam cells,Food ScienceandNutrition,2023,11(6):3141-3153
Zhang D,Tang D,Liu PT,Tao L,Lu LM,Isolation of tumor stem-like cells from primary laryngeal squamous cell carcinoma cells (FD-LS-6),Hum Cell,2023, 2023 Sep 27
Zhou L, Hou Y, Pan X, Wang X, Jin H, Yang X, Wang K, Ding X, Wang K, Zhu M, Pan Y, Wang W, Lu L,Trichosanthin-derived peptide Tk-PQ attenuates immune rejection in mouse tracheal allotransplant model by suppressing PI3K-Akt and inducing type II immune polarization ,Int Immunopharmacol,2023,125(Pt A):111081
Heng Y, Zhu X, Wu Q, Lin H, Ding X, Tao L, Li-Ming Lu,High Expression of Tumor HLA-DR Predicts Better Prognosis and Response to Anti-PD-1 Therapy in Laryngeal Squamous Cell Carcinoma,Transl Oncol,2023,33:101678
Di Tang, Duo Zhang, Yu Heng, Xiao-ke Zhu, Han-qing Lin, Jian Zhou, Lei Tao, Li-ming Lu,Tumor-infiltrating PD-L1+ Neutrophils Induced by GM-CSF Suppress T Cell Function in Laryngeal Squamous Cell Carcinoma and Predict Unfavorable Prognosis,Journal of Inflammation Research,2022,16;15:1079-109
Di Tang,Duo Zhang,Yu Heng,Xiao-ke Zhu,Han-qing Lin,Jian Zhou,Lei Tao, Li-ming Lu,Tumor-infiltrating PD-L1+ Neutrophils Induced by GM-CSF Suppress T Cell Function in Laryngeal Squamous Cell Carcinoma and Predict Unfavorable Prognosis., Journal of Inflammation Research,2022,15:1079-1097
Wang T,Zhang D,Tang D,Heng Y,Lu LM,Tao L,The role of systemic inflammatory response index (SIRI) and tumor-infiltrating lymphocytes (TILs) in the prognosis of patients with laryngeal squamous cell carcinoma,J Cancer Res Clin Oncol,2022,149(9):5627-5636
Han Y,Ouyang X,Chen Y,Lai S,Sun H,Wu N,Ruan C,Lu L,Su B,scRNA-seq profiling of neonatal and adult thymus-derived CD4+ T cells by a T cell origin-time tracing model.,J Mol Cell Biol,2022,14(12):mjac072
Rui Guo,Shun-Yuan Lu,Jin-Xia Ma,Qian-Lan Wang,Lu Zhang,Ling-Yun Tang,Yan Shen,Chun-Ling Shen,Jin-Jin Wang,Li-Ming Lu,Zhu-GangWang,Hong-Xin Zhang,RIG-I acts as a tumor suppressor in melanoma via regulating the activation of the MKK/p38MAPK signaling pathway, Hum Cell,2022,35(4):1071-1083.
Ruan D,Ye ZW,Yuan S,Li Z,Zhang W,Ong CP,Tang K,Ka Ki Tam TT,Guo J,Xuan Y,Huang Y,Zhang Q,Lee CL,Lu L,Chiu PCN,Yeung WSB,Liu F,Jin DY,Liu P,Human early syncytiotrophoblasts are highly susceptible to SARS-CoV-2 infection,Cell Rep Med,2022,3(12):100849
Kai Wang, Man Zhang, Jiao Wang, Jizhuang Luo, Pan Sun, Haizhen Jing, Rong Li, Changqing Pan, Li-Ming Lu,A systematic analysis identifies key regulators involved in cell proliferation and potential drugs for the treatment of human lung adenocarcinoma,Frontiers in Oncology-Thoracic Oncology,2021,11:4-15
ZongAn Chen, Zhen Gao, LingLing Xia, XiaoQing Wang, Li-Ming Lu, XiaoLi Wu,Dysregulation of DPP4-CXCL12 balance by TGF-β1/SMAD pathway promotes CXCR4+ inflammatory cell infiltration in keloid scars,Journal of Inflammation Research,2021,14:4169-4180.
Duo Zhang, Di Tan, Yu Heng, Xiao-Ke Zhu, Liang Zhou, Lei Tao, Li-Ming Lu,Prognostic Impact of Tumor-Infiltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma Patients,Laryngoscop,2021,131(4):E1249-E1255.
Zhang Yu,Zhou Lin,Gu Xiang,Feng Xuan,Ding Ping,Xia Qiang,Li-Ming Lu,CXCL8high inflammatory B cells in the peripheral blood of patients with biliary atresia are involved in disease progression,Immunology and Cell Biology,2020,98(8):682-692
He Yu-Bin,Guo Jiang-Hong,Wang Chong,Zhu Dan,Lu Li-Ming,IL-33 promotes the progression of nonrheumatic aortic valve stenosis via inducing differential phenotypic transition in valvular interstitial cells.,Journal of cardiology.,2020,75(2):124-133
Yi Xue , Di Tang , Sheng-Jie Li , Jian Zhou , Chi-Yao Hsueh , Dan-Dan Zhao , Yu Heng , Lei Tao, Li-Ming Lu ,Link Between CIITA rs3087456 Polymorphism and the,Pathol Res Pract,2020,216(1):152793
Christopher D Nishimura, Marc C Pulanco, Wei Cui, Liming Lu, Xingxing Zang, PD-L1 and B7-1 Cis-Interaction: New Mechanisms in Immune Checkpoints and Immunotherapies,Trends Mol Med,2020,27(3):207-219
Zhang Na, Sun Pan, Jin Haizhen, Yang Yuqin, Zhao Qingya, Zhou Lin, Guo Lili, Yang Xiaohua, Li-Ming Lu,Chidamide combined with paclitaxel effectively reverses the expression of histone deacetylase in lung cancer,Anti-Cancer Drugs,2020,31(7):702-708
Jian Zhou, Liang Zhou, Duo Zhang, Wei-Jing Tang, Di Tang, Xiao-Ling Shi, Yue Yang, Lin Zhou, Fei Liu, Yong Yu, Pentao Liu, Lei Tao, Li-Ming Lu ,BCL11A promotes the progression of laryngeal squamous cell carcinoma,Frontiers in,2020,0.677083
Gao Xuefei, Nowak-Imialek Monika, Chen Xi, Chen Dongsheng, Herrmann Doris, Ruan Degong, Chen Andy Chun Hang, Eckersley-Maslin Melanie A, Ahmad Shakil, Lee Yin Lau,Kobayashi Toshihiro, Ryan David, Zhong Jixing, Zhu Jiacheng, Wu Jian, Lan Guocheng, Petkov Stoyan, Yang Jian, Antunes Liliana, Campos Lia S, Fu Beiyuan, Wang Shengpeng, Yong Yu, Wang Xiaomin, Xue Song-Guo, Ge Liangpeng, Liu Zuohua, Huang Yong, Nie Tao, Li Peng, Wu Donghai, Pei Duanqing, Zhang Yi, Lu Liming, Yang Fengtang. Kimber Susan J, Reik Wolf, Zou Xiangang, Shang Zhouchun, Lai Liangxue, Surani Azim, Tam Patrick P L, Ahmed Asif, Yeung William Shu Biu, Teichmann Sarah A, Niemann Heiner, Liu Pentao,Establishment of porcine and human expanded potential stem cells,Nature cell biology,2019,21(6): 687
Jun Lu, Hua Zhong, Tianqing Chu, Xueyan Zhang, Rong Li, Jiayuan Sun, Runbo Zhong, Yuqin Yang, Mohammad Shah Alam, Yuqing Lou, Jianlin Xu, Yanwei Zhang, Jun Wu, Xiaowei Li, Xiaodong Zhao, Kai Li, Liming Lu*, Baohui Han,Role of anlotinib-induced CCL2 decrease in anti-angiogenesis and response prediction for non-small cell lung cancer therapy,European Respiratory Journal,2019,53(3)
Guo-wei Tu ,Min-jie Ju, Guang-wei Hao,Guo-guang Ma, Jun-yi Hou, Xue-peng Zhang,Zhe Luo, Li-ming Lu,CXCL16/CXCR6 Is Involved in LPS-induced Acute Lung Injury via P38 Signaling,Cell Physiol Biochem,2019,23(8):5380-5389
Yi xue, Huai-Dong Du, Di Tang, Duo Zhang, Jian Zhou, Chang-Wen Zhai, Cun-Cun Yuan, Chi-Yao Hsueh, Sheng-Jie Li, Yu Heng, Lei Tao,Li-ming Lu*,Correlation Between the NLRP3 Inflammasome and the Prognosis of Patients With LSCC,FRONTIERS IN ONCOLOGY,2019,0.096389
衡宇, 查亚芳, 顾燕妮, 沈朝斌,路丽明,2018 年美国儿童预防接种最新指南解读及其与我国现状比较,现代免疫学,2018,38(04): 350-353
Xiao-yang Zhang, Lin Zhou, Zhen Guo, Ye Kong, Wei Zhang, Liming Lu*,Xin Li*,Regulatory T Cells may Play an Protection Role in Lung Injury after Operation in Rheumatic Heart Disease, Journal of Thoracic Disease,2018,10(6)
Yue Wang, Qing Li, Lin Zhou, Xueping Ding, Liming Lu,Peptede TK-PQ induces immunosuppression in skin allogeneic transplantation via increasing Foxp3+ Treg and impeding nuclear translocation of NF-κB ,Molecular Immunology,2018,101:597-607.
Xiaoyan Yu, Yimin Lao, Xiao-Lu Teng, Song Li, Yan Zhou, Feixiang Wang, Xinwei Guo, Siyu Deng, Yuzhou Chang, Xuefeng Wu, Zhiduo Liu, Lei Chen, Liming Lu, Jinke Cheng, Bin Li, Bing Su, Jin Jiang, Hua-Bing Li, Chuanxin Huang, Jing Yi and Qiang Zou,SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation,Nature communications,2018,9(1): 3157
Xiaoyan Yu, XiaoLu Teng, Feixiang Wang, Yuhan Zheng, Guojun Qu, Yan?Zhou, Zhilin Hu, Zhongqiu Wu, Yuzhou Chang, Lei Chen,HuaBing Li, Bing Su, Liming Lu, Zhiduo Liu, ShaoCong Sun, and Qiang Zou,Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome,J Exp Med,2018,3;215(9):2463-2476
李健,郭震,路丽明,李欣,无血预充大鼠体外循环模型的建立,中国体外循环杂志,2018,Vol.16 No. 3
李健,郭震, 路丽明,李欣,无血预充大鼠体外循环模型的建立,中国体外循环杂志,2018,16(03):184-188
Weimin Fan, Yali Xu, Yue Liu, Zhengqing Zhang, Liming Lu ,Zhide Ding ,Obesity or Overweight, a Chronic Inflammatory Status in Male Reproductive System, Leads to Mice and Human Subfertility ,Frontiers in Physiology ,2018,1.109028
陈广洁, 谢长宜, 钮晓音, 蒋黎华, 聂红, 路丽明, 席晔斌, 葛海良,机体防御与免疫整合课程的实践与研究,中国高等医学教育,2018,(4): 16-17
Zhang D, Zhou J, Tang D, Zhou L, Chou L, Chou KY, Tao L, Lu LM.,Neutrophil infiltration mediated by CXCL5 accumulation in the laryngeal squamous cell carcinoma microenvironment: A mechanism by which tumour cells escape immune surveillance,Clin Immunol,2017,175:34-40
Yang J, Ryan DJ, Wang W, Tsang JC, Lan G, Masaki H, Gao X, Antunes L, Yu Y, Zhu Z, Wang J, Kolodziejczyk AA, Campos LS, Wang C, Yang F, Zhong Z, Fu B, Eckersley-Maslin MA, Woods M, Tanaka Y, Chen X, Wilkinson AC, Bussell J, White J, Ramirez-Solis R, Reik W, G?ttgens B, Teichmann SA, Tam PPL, Nakauchi H, Zou X, Lu L, Liu P,Establishment of mouse expanded potential stem cells,Nature ,2017,550(7676)
万建伟,周琳,赵丹丹,杨玉琴,路丽明,联烯化合物PHPO 对肺癌细胞株A549 增殖及凋亡的影响,上海交通大学学报(医学版),2017,37(10):1433-1439
ZongAn Chen, Lin Zhou, TaeHao Won, Zhen Gao, XiaoLi Wu,LiMing Lu,Characterization of CD45RO+ Memory T Lymphocytes in Keloid Disease,British Journal of Dermatology,2017,178(4):940-950
张晓阳,路丽明,李 欣,调节性T细胞和辅助性T细胞与体外循环后肺损伤相关性 的研究,中国体外循环杂志,2017,15(2):81-84
WEIJING TANG, LEI TAO, LI MING LU, DI TANG,XIAOLIN SHI,Role of T helper 17 cytokines in the tumour immune inflammation,ONCOLOGY LETTERS,2017,14(1): 561-568
Zhou J, Yang Y, Zhang D, Zhou L, Liu F, Tao L, Lu LM,Association of the recurrence of vocal leukoplakia with MDM2-309 variants over a 2-year period: a prospective study,Acta Otolaryngol,2016,136(1):95-9
于浩然,张柳蕙,刘威,周琳,丁旭苹,蒋黎华,路丽明,RBL教学对临床医学本科生综合能力培养的作用,中华医学教育探索杂志,2016,15.10(2016);1034-1038
Yu Y, Tsang JC, Wang C, Clare S, Wang J, Chen X, Brandt C, Kane L, Campos LS, Lu L, Belz GT, McKenzie AN, Teichmann SA, Dougan G, Liu P,Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway,Nature,2016,539(7627):102-106
Zhou J, Zhang D, Zhou L, Yang Y, Liu F, Tao L, Lu LM,Association of the recurrence and canceration rate of vocal leukoplakia with interleukin-10 promoter variants over a 2-year period,Acta Oto-Laryngologica,2016,2016 Jun 14:1-7
Zhang D, Tang WJ, Tang D, Zhou J, Chou L, Tao L, Lu LM,The ratio of CD4/CD8 T-cells in human papillomavirus-positive laryngeal squamous cell carcinoma accounts for improved outcome,Acta Otolaryngol ,2016,136(8):826-33
Li Z, Yang N, Zhou L, Gu P, Wang H, Zhou Y, Zhou P, Lu L, Chou KY,A peptide tetramer Tk-tPN induces tolerance of cardiac allografting by conversion of type 1 to type 2 immune responses via the Toll-like receptor 2 signal-promoted activation of the MCP1 gene,Immunology,2016, 147(3):355–366
周琳,高文,路丽明,肺移植后闭塞性细支气管炎免疫学发病机制及治疗新策略,现代免疫学,2016,36(1):67-71
Tang.D, W. J. Tang, X. L. Shi, W. P. Li, H. Zhou, Lu L*, L. Tao,Association of the microsatellite (GT)n repeat polymorphisms of the HO-1 gene promoter and corresponding serum levels with the risk of laryngeal squamous cell carcinoma,Acta Otolaryngol,2016,136, 806-11
Zhao AM, Xu HJ, Kang XM, Zhao AM, Lu LM,New insights into myeloid-derived suppressor cells and their roles in feto-maternal immune cross-talk,J Reprod Immunol,2016,113:35-41
Yang J, Wang W, Ooi J, Campos LS, Lu L, Liu P ,Signalling Through Retinoic Acid Receptors is Required for Reprogramming of Both Mouse Embryonic Fibroblast Cells and Epiblast Stem Cells to Induced Pluripotent Stem Cells,Stem Cells,2015,33(5):1390-404.
Zhang D, Chen B, Zhou J, Zhou L, Li Q, Liu F, Chou KY, Tao L, Lu LM,Low concentrations of trichosanthin induce apoptosis and cell cycle arrest via c-Jun N-terminal protein kinase/mitogen-activated protein kinase activation,Mol Med Rep,2015,11(1):349-56
Yu Y, Wang C, Clare S, Wang J, Lee SC, Brandt C, Burke S, Lu L, He D, Jenkins NA, Copeland NG, Dougan G, Liu P,The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development,J Exp Med,2015,212(6):865-74
Jason C. H. Tsang, Yong Yu, Shannon Burke, Florian Buettner, Cui Wang, Aleksandra A. Kolodziejczyk, Sarah A. Teichmann, Liming Lu, and Pentao Liu,Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells,Genome Biology,2015,16(1):178
Xuefei Gao, Jason C.H. Tsang, Fortis Gaba, Donghai Wu, Lu. L, Pentao Liu,Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers,Nucleic Acids Research,2014,42(20):Pp. e155
Zhou J, Zhang D, Chen B, Li Q, Zhou L, Liu F, Chou KY, Tao L, Lu LM,Association of interleukin-10 promoter polymorphisms and corresponding plasma levels with susceptibility to laryngeal squamous cell carcinoma,Oncol Lett,2014,7(5):1721-1727
Jason CH Tsang, Xuefei Gao, Lu L, Pentao Liu,Cellular reprogramming by transcription factor engineering,Current Opinion in Genetics and Development,2014,28:1-9
Yang N, Li Z, Jiao Z, Gu P, Zhou Y, Lu L, Chou KY,A Trichosanthin-derived peptide suppresses type 1 immune responses by TLR2-dependent activation of CD8(+)CD28(-) Tregs,Clin Immunol.,2014,153(2):277-87
Liu F, Pan X, Zhou L, Zhou J, Chen B, Shi J, Gao W, Lu L,Genetic polymorphisms and plasma levels of interleukin-22 contribute to the development of nonsmall cell lung cancer,DNA Cell Biol,2014,33(10):705-14
Chen B, Zhang D, Zhou J, Li Q, Zhou L, Li SM, Zhu L, Chou KY, Zhou L, Tao L, Lu LM,High CCR6/CCR7 expression and Foxp3+ Treg cell number are positively related to the progression of laryngeal squamous cell carcinoma,Oncol Rep,2013,30(3):1380-90
李青 周光炎 路丽明,天花粉蛋白抑制同种异体混合淋巴细胞反应与诱导IL9+IL10+IL24Th9细胞间关系的初步探讨,现代免疫学,2012,32(2): 94-98
邵晓轶 周云 路丽明 马妍慧杨志强 周光炎,p38MAPK信号通路在B7H1-Ig融合蛋白诱导Tr1细胞分化中的作用 ,上海交通大学学报(医学版),2012,32(11):1448-1454
Zhiqiang Yang, Peng Gu, Xiaoyi Shao, Zuoqing Li, Yun Zhou, Liming Lu, Kuang-Yen Chou, Mutated MHC class II transactivator upregulates IL-33-dependent differentiation of Th2 subset through Nod2 binding for NLR signaling initiation,J Biological Chemistry,2012, Mar 23;287(13) :9972-9981
邵晓轶 马妍慧 路丽明 周云 杨志强 顾鹏 李佐青 周光炎,B7H1-Ig诱导Tr1细胞向CD4+CD25+Foxp3Treg细胞转化的研究,现代免疫学,2012,32(6): 441-449
周琳 周光炎 路丽明,IL-10 的双向免疫调节作用,细胞与分子免疫学杂志,2012,28(10):1100-1102
李青 周光炎 路丽明,Th9:亚群特征、相关转录因子及其分化的可塑性,现代免疫学,2011,31:340-343
李青 周光炎 路丽明,IL-9的研究进展。, 中国免疫学杂志,2011,27:848-850
Ding Q, Lu LM, Xiaorong Zhou, Zhou Y, Chou KY. ,Human PD-L1-overexpressing porcine vascular endothelial cells induce functionally suppressive human CD4+CD25hiFoxp3+Treg cells,Journal of Leukocyte Biology,2011,Jul, 90 (1):77-86
Ding Q, Lu LM, Xiaorong Zhou, Zhou Y, Chou KY. ,Human PD-L1-overexpressing porcine vascular endothelial cells induce functionally suppressive human CD4+CD25hiFoxp3+Treg cells,Journal of Leukocyte Biology,2011,Jul, 90 (1):77-86
Wang B, Jiao Z, Shao X, Lu LM, Yang N, Zhou X, Xin L, Zhou Y, Chou KY.,Phenotypic alterations of dendritic cells are involved in suppressive activity of trichosanthin-induced CD8+CD28- regulatory T cells,Journal of Immunology,2010, Jul 1: 185(1):79-88
Ding Q,Lu LM, Wang BL, Zhou Y, Chou KY,B7H1-Ig fusion protein activates the CD4+IFN-?gamma receptor+ type 1 T regulatory subset through IFN-gamma?-secreting Th1 cells .,J Immunol,2006,177:3606-3614
路丽明 李宁丽 沈佰华 周光炎,TRAIL分子胞外区基因工程蛋白的制备与鉴定 ,中国实验诊断学,2003,2003,7(6).477-479
陈斌 陶磊 周梁 周光炎 路丽明 ,CD4+CD25+Foxp3+Treg细胞与喉癌发病的相关研究,现代免疫学, , 32(1): 40-46
陈斌,路丽明,陶磊,周梁,趋化因子受体CCR6,CCR7与CD4+CD25+Foxp3+调节性T细胞在喉鳞癌中表达及其与淋巴转移的相关性,中华耳鼻咽喉头颈外科杂志, , 45(9):751-758
