刘畅
性 别：女
联系电话：021-63846590
邮箱地址：tiantianlc@sjtu.edu.cn
培养单位：基础医学院
学科/专业
研究方向
科研项目
代表性论文
科研获奖
专利授权
噬菌体调控菌群在慢性疾病中的干预研究
肠道噬菌体组研究
肠道微生物与宿主的相互作用
2019-01~2021-12，横向 ，AgeLOC Defense抗雾霾调节免疫功能开发，课题负责人
2016-05~2017-12，横向课题 ，kappa在肠易激综合症治疗和预防中的作用及其机制探究，课题负责人
2015-01~2017-12，国家自然科学基金 ，植物乳杆菌激活NHE8信号通路并在炎症性肠病中发挥保护 作用可能的机制探究，课题负责人
Qian J, Wu ZY, Ma LC, Zhu YZ, Zhang Y, Li M, Guo XK, Liu C*.，Metagenomic insights into correlation of microbiota and antibiotic resistance genes in the worker-pig-soil interface: A One Health surveillance on Chongming Island, China，Journal of Hazardous Materials Advances，2025，2025-18-100648.
Chen YM, Ma LC, Chen WY, Chen YW, Cheng ZL, Zhu YZ, Li M, Zhang Y, Guo XK, Liu C*，In vitro evaluation of the probiotic properties and whole genome sequencing of Lacticaseibacillus rhamnosus J3205 isolated from home-made fermented sauce. ，Microorganisms ，2025，2025-13-1643.
Yu SH, Ge YH, Zhang LJ, Li YQ, Zhang W, Liu C, Peng SJ，Dietary exposure assessment of perchlorate and chlorate in infant formulas marketed in Shanghai, China，Science in One Health，2024，3-100062
Chen YM, Chen WY, Cheng ZL, Chen YW, Li M, Ma LC, Zhou N, Qian J, Zhu YZ, Liu C*. ，Global burden of HIV-negative multidrug-and extensively drug-resistant tuberculosis based on Global Burden of Disease Study 2021，Science in One Health，2024，3-100072.
Ma LC, Li M, Chen YM, Chen WY, Chen YW, Cheng ZL, Zhu YZ, Zhang Y, Guo XK, and Liu C*.，Genomic insight into zoonotic and environmental Vibrio vulnificus: Strains with T3SS2 as a novel threat to public health，Microorganisms ，2024，12(11)- 2375.
Ma LC, Zhao HQ, Logan Blair Wu, Cheng ZL, Liu C* ，Impact of the microbiome on human, animal, and environmental health from a One Health perspective.，Science in One Health，2023，100037
Wang Y, Liu Z, Chen Q, Yi L, Xu Z, Cai M, Qin J, Zhang Y, Du G, Hong J, Guo X and Liu, C* ，Isolation and characterization of novel Fusobacterium nucleatum bacteriophages.，Front. Microbiol.，2022，13-945315
Qian J, Wu ZY, Zhu YZ, Liu C*，One Health: a holistic approach for food safety in livestock.，Science in One Health，2022，100015
Fu, XM, Lyu L, Wang Y, Zhang Y, Guo, XK, Chen Q, Liu, C*，Safety assessment and probiotic characteristics of Enterococcus lactis JDM1.，Microb Pathog.，2022，163-105380
Cai MF, Pu, BC, Wang Y, Lv L, Jiang CY, Fu XM, Zhang Y, Zhao W, Dong K, Yang Y, Liu YM, Wei YL, Zhang ZY, Li JH, Guo XK, Liu C*, Qin JH*，A Plasmid With Conserved Phage Genes Helps Klebsiella pneumoniae Defend Against the Invasion of Transferable DNA Elements at the Cost of Reduced Virulence.，Front. Microbiol.，2022，17-13-827545
Jin, LL, Deng L, Mark Bartlett, Ren YP, Lu JH, Chen Q, Pan YX, Wang H, Guo XK, Liu C*，A Novel Herbal Extract Blend Product Prevents Particulate Matters-Induced Inflammation by Improving Gut Microbiota and Maintaining the Integrity of the Intestinal Barrier. ，Nutrients.，2022，14(10)-10-3390
Chen, Q., Ma, X., Li, C., Shen, Y., Zhu, W., Zhang, Y., Guo, X., Zhou, J., and Liu, C*.，Enteric Phageome Alterations in Patients With Type 2 Diabetes.，Front Cell Infect Microbiol，2021，10-575084
Zhou D, Pan Q, Liu XL, Yang RX, Chen YW, Liu C, Fan JG.，Clostridium butyricum B1 alleviates high-fat diet-induced steatohepatitis in mice via enterohepatic immunoregulation，J Gastroenterol Hepatol，2017，32(9):1640-1648
Chen Q; Ren YP; Lu JH; Mark Bartlett; Chen L; Zhang Y; Guo XK; Liu C *，A Novel Prebiotic Blend Product Prevents Irritable Bowel Syndrome in Mice by Improving Gut Microbiota and Modulating Immune Response，Nutrients.，2017，9(12)-1341
Wei Y, Ye L, Li Y, Yang F, Liu D, Guo X, Tang R, Liu C.，Functional characterization of RelBE toxin-antitoxin system in probiotic Bifidobacterium longum JDM301.，Acta Biochim Biophys Sin，2016，48(8):741-9
Wei YX, Ye L, Liu DB, Zhang ZY, Liu C, Guo XK.，Activation of the chromosomally encoded mazEFBif locus of Bifidobacterium longum under acid stress.，International Journal of Food Microbiology，2015， 207: 16-22
Liu C, Xu H, Zhang B, Malin E. V. Johansson, Li J, Gunnar C. Hansson, Fayez K Ghishan，NHE8 plays an important role in mucosal protection via its effect on bacterial adhesion. ，Am J Physiol Cell Physiol.，2013，305(1):C121-128
Zhang ZY, Liu C, Zhu YZ, Wei YX, Tian F, Zhao GP, Guo XK，Safety assessment of Lactobacillus plantarum JDM1 based on the complete genome, ，International Journal of Food Microbiology，2012，153: 166-170
Wei YX, Zhang ZY, Liu C, Pradeep K. Malakar, Guo XK，Safety assessment of Bifidobacterium longum JDM301 based on complete genome sequences. ，World J Gastroenterol ，2012，18(5): 479-488
Dong K, Li QT, Liu C, Zhang YY, Zhao GP, Guo XK ，Cloning and Characterization of Three cheB Genes in Leptospira interrogans.，Acta Bioch Bioph Sin ，2010，42(3):216-223
Wei YX, Zhang ZY, Liu C, Guo XK，Complete Genome Sequence of Bifidobacterium longum JDM301.， J Bacteriol ，2010，192 (15): 4076-4077
Liu C, Zhang ZY, Dong K, Guo XK，Adhesion and immunomodulatory properties of Bifidobacterium lactis HN019 to intestinal epithelial cells INT-407. ，World Journal of Gastroenterology，2010，16(18):2283-2290
Liu C, Zhang ZY, Dong K, Yuan JP, Guo XK，Antibiotic resistance of probiotic strains of lactic acid bacteria isolated from marketing food and drugs. ，Biomedical and Enviromental Science，2009，22: 401-402
Zhang ZY, Liu C, Guo XK ，Complete genome sequence of Lactobacillus plantarum JDM1. ，J Bacteriol.，2009，191(15):5020-5021