- 基本信息
导师姓名:
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刘智多
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学科代码:
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100100
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性别:
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男
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学科名称:
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基础医学
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培养单位:
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基础医学院
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三级学科
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导师类型:
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博士生导师
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专业领域名称:
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联系方式:
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021-63846590-776749
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专业领域代码:
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邮编:
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200025
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邮箱地址:
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zhiduo.liu@shsmu.edu.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
- 科研项目
31870871 | CCR4控制调节性T细胞的空间分布及其对自身免疫性疾病的作用 | 国家自然科学基金委员会 |
2019-01~2022-12
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60万元
| 课题负责人 |
1710000261 | 海外高层次人才项目 | 上海市教育委员会 |
2017-09~2020-08
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100万元
| 课题负责人 |
17PJ1408300 | 骨髓中免疫前体细胞发育的微环境 | 上海市科学技术委员会 |
2017-07~2019-06
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20万元
| 课题负责人 |
17ZR1425000 | 骨髓里记忆性T细胞所处的微环境的研究 | 上海市科学技术委员会 |
2017-05~2020-04
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20万元
| 课题负责人 |
- 学术论文
Yu X, Lao Y, Teng XL, Li S, Zhou Y, Wang F, Guo X, Deng S, Chang Y, Wu X,, Chen L, Lu LM, Cheng J, Li B, Su B, Jiang J, Li HB, Huang C, Yi J, Zou Q.
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SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation.
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Nature Communications.
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2018
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9(1):3157-3167.
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Yu X, Teng XL, Wang F, Zheng Y, Qu G, Zhou Y, Hu Z, Wu Z, Chang Y, Chen L, Li HB, Su B, Lu L,, Sun SC, Zou Q.
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Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome.
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Journal of Experimental Medicine.
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2018
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215(9):2463-2476.
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Oyler-Yaniv A, Oyler-Yaniv J, Whitlock BM,, Germain RN, Huse M, Altan-Bonnet G, Krichevsky O.
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A Tunable Diffusion-Consumption Mechanism of Cytokine Propagation Enables Plasticity in Cell-to-Cell Communication in the Immune System.
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Immunity.
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2017
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46(4):609-620.
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Veres TZ, Kopcsányi T, van Panhuys N, Gerner MY,, Rantakari P, Dunkel J, Miyasaka M, Salmi M, Jalkanen S, Germain RN.
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Allergen-Induced CD4+ T Cell Cytokine Production within Airway Mucosal Dendritic Cell-T Cell Clusters Drives the Local Recruitment of Myeloid Effector Cells.
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Journal of Immunology.
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2017
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198(2):895-907.
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, Gerner MY, Van Panhuys N, Levine AG, Rudensky AY, Germain RN.
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Immune homeostasis enforced by co-localized effector and regulatory T cells.
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Nature.
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2015
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528(7581):225-30.
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Lo B, Zhang K, Lu W, Zheng L, Zhang Q, Kanellopoulou C, Zhang Y,, Fritz JM, Marsh R, Husami A, Kissell D, Nortman S, Chaturvedi V, Haines H, Young LR, Mo J, Filipovich AH, Bleesing JJ, Mustillo P, Stephens M, Rueda CM, Chougnet CA, Hoebe K, McElwee J, Hughes JD, Karakoc-Aydiner E, Matthews HF, Price S, Su HC, Rao VK, Lenardo MJ, Jordan MB.
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Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy.
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Science.
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2015
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349(6246):436-40.
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Li Z, Zhang Y,, Wu X, Zheng Y, Tao Z, Mao K, Wang J, Lin G, Tian L, Ji Y, Qin M, Sun S, Zhu X, Sun B.
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ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1).
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Nature Immunology.
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2011
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12(2):178-85.
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Yang XO, Angkasekwinai P, Zhu J, Peng J,, Nurieva R, Liu X, Chung Y, Chang SH, Sun B, Dong C.
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Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment.
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Nature Immunology.
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2009
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10(12):1260-6.
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Bi E, Huang C, Hu Y, Wu X, Deng W, Lin G,, Tian L, Sun S, Mao K, Zou J, Zheng Y, Sun B.
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Novel function of perforin in negatively regulating CD4(+) T cell activation by affecting calcium signaling.
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Cell Research.
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2009
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19(7):816-27.
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,, Li Z#, Mao K, Zou J, Wang Y, Tao Z, Lin G, Tian L, Ji Y, Wu X, Zhu X, Sun S, Chen W, Xiang C, Sun B.
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Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling.
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Journal of Immunology.
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2009
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183(10):6320-9.
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Xie D#,, Li Z, Ji Y, Chen J, Sun B.
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Differential expression of neutrophilic granule proteins between Th1 and Th2 cells.
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Acta Biochimica et Biophysica Sinica.
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2007
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39(1):67-72.
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