- 基本信息
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导师姓名：
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李华兵
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学科代码：
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100100
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性别：
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男
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学科名称：
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基础医学
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培养单位：
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基础医学院
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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联系方式：
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办公室地址：上海黄浦区重庆南路280号西5楼602室；
办公室电话：021-63846590 / 776794;
邮箱：huabing.li@shsmu.edu.cn;
实验室网址：https://huabingli.wixsite.com/lilab
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专业领域代码：
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邮编：
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200025
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邮箱地址：
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huabing.li@shsmu.edu.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
- 科研项目
| 001 | 免疫T细胞中RNA修饰的功能研究 | 国家海外青年高层次人才计划 |
2019-01~2021-12
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300万元
| 课题负责人 |
| 91753141 | m6A RNA 甲基化修饰动态变化对CD8 T细胞功能调控的研究 | 国家自然科学基金重大研究计划培育项目 |
2018-01~2020-12
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70万元
| 课题负责人 |
| 003 | 上海高校特聘教授岗位计划资助 | 上海市教委高校特聘教授 |
2017-09~2020-08
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100万元
| 课题负责人 |
| 004 | 上海交通大学医学院院基金 | 引进人才启动基金 |
2017-08~2023-07
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300万元
| 课题负责人 |
- 学术论文
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Hwang SS*, Lim J*, Yu Z, Kong P, Sefik E, Xu H, Harman CCD, Kim LK, Lee GR,, Flavell RA
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mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence.
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Science.
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2020
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Mar 13;367(6483):1255-1260.
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Wang J, Flavell RA#,
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Antiviral immunity: a link to bile acids
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Cell Research
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2019
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29: 177~178
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Zhang X, Flavell RA#,
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hnRNPA2B1: a nuclear DNA sensor in antiviral immunity.
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Cell Research
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2019
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0:1–2.
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Tong J, Flavell RA#,
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RNA m6A modification and its function in diseases
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Front Med
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2018
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12(4): 481~489
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Liu Y,, Flavell RA#.
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cGAS activation in phased droplets
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Cell Research
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2018
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28: 967~968
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Yu X*, Teng XL*, Wang F*, Zheng Y*, Qu G, Zhou Y, Hu Z, Wu Z, Chang Y, Chen L,, Su B, Lu L #, Liu Z #, Sun SC #, Zou Q #.
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Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome.
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J Exp Med.
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2018
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2018 Sep 3;215(9):2463-2476.
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Yu X*, Lao Y*, Teng XL*, Li S, Zhou Y, Wang F, Guo X, Deng S, Chang Y, Wu X, Liu Z, Chen L, Lu LM, Cheng J, Li B, Su B, Jiang J,, Huang C#, Yi J#, Zou Q#.
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SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
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Nat Commun
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2018
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9(1): 3157
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Tong J#, Cao G#, Zhang T#, Esen Sefik, Vesely MCA, Broughton JP , Zhu S, Li Hb, Li B, Chen L, Chang HY, Su B, Flavell RA* ,
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m6A mRNA methylation sustains Treg suppressive functions
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Cell Research
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2018
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28(2)：253–256
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Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm NW, Yang Y, Yu H,, Wang G, Lei X, de Zoete MR, Zhao J, Zheng Y, Chen H, Zhao Y, Jurado KA, Feng N, Shan L, Kluger Y, Lu J, Abraham C, Fikrig E, Greenberg HB, Flavell RA
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Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.
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Nature
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2017
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546(7660):667-670
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, Tong J#, Zhu S#, Batista PJ, Duffy EE, Zhao J, Bailis W, Cao G, Kroehling L, Wang G, Broughton JP, Chen YG, Kluger Y, Simon MD, Chang HY, Yin Z§, Flavell RA*
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m6A mRNA methylation controls T cell homeostasis by targeting IL-7/STAT5/SOCS pathway
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Nature
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2017
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548(7667): 338-342
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Chromosome Conformation Capture in Drosophila
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Methods in Molecular Biology
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2016
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1480: 207-212
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Hu B#, Jin C#,, Tong J, Ouyang X, Cetinbas NM, Zhu S, Strowig T, Lam FC, Zhao C, Henao-Mejia J, Yilmaz O, Fitzgerald KA, Eisenbarth SC, Elinav E, Flavell RA*
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The DNA Sensing Aim2 Inflammasome Controls Radiation Induced Cell death and Tissue Injury
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Science
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2016
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354 (6313): 765-768
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Cao G#,, Yin Z, Flavell RA*
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Recent advances in dynamic m6A RNA modification
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Open Biology
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2016
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6(4): 160003
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, Jin C#, Chen Y#, Flavell RA*
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Inflammasome activation and metabolic disease progression
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Cytokine Growth Factor Rev
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2014
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25(6):699-706
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Zhu S#,, Flavell RA*
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Resemble and Inhibit: When RLR Meets TGF-β
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Mol Cell
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2014
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56(6):719-20
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, Ohno K, Gui H, and Pirrotta V*
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Insulators target active genes to transcription factories and Polycomb-repressed genes to PcG bodies
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PLoS Genet
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2013
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9(4): e1003436
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Pirrotta V*,
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A view of nuclear Polycomb bodies
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Curr. Opin. Genet. Dev
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2011
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22(2):101-9
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, Muller M, Bahechar I, Kyrchanova O, Ohno K, Georgiev P, and Pirrotta V*
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Insulators, not Polycomb Response Elements, are required for long-range interactions between Polycomb targets in Drosophila
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Mol. Cell. Biol
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2010
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31(4):616-25
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