- 基本信息
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导师姓名：
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张明亮
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学科代码：
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100100
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性别：
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男
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学科名称：
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基础医学
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培养单位：
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基础医学院
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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联系方式：
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mingliang.zhang@shsmu.edu.cn
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专业领域代码：
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邮编：
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200025
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邮箱地址：
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mingliang.zhang@shsmu.edu.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中国医师协会眼科分会（学组）委员
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中国细胞生物学会青年工作委员会委员
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- 科研项目
| 6 | 上海市“科技创新”行动计划 | 上海市科委 |
2019-11~2022-11
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79万元
| 课题负责人 |
| 5 | 国家自然科学基金面上项目 | 国家自然科学基金委员会 |
2018-01~2021-12
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65万元
| 课题负责人 |
| 2 | 上海市高层次人才计划 | 上海市教委 |
2018-01~2020-12
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100万元
| 课题负责人 |
| 1 | 上海市高层次人才计划 | 上海市科委 |
2017-06~2019-05
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20万元
| 课题负责人 |
- 学术论文
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Zhou-Li Cheng, Meng-Li Zhang, Huai-Peng Lin, Chao Gao, Jun-Bin Song, Zhi-Hong Zheng, Lin-Peng Li, Ya-Nan Zhang, Xiao-Qi Shen, Hao Zhang, Zheng-hui Huang, Wu-qiang Zhan, Cheng Zhang, Yi-Ping Sun, Lu-Bing Jiang, Lei Sun, Ze Li, Yanhui Xu, Chen Yang, Yuan-Long Ge, Yong Zhao, Xing-Guo Liu, Hui Yang, Peng-Yuan Liu, Xing Guo, Kun-Liang Guan, Yue Xiong,, and Dan Ye*
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The Zscan4-Tet2 transcription nexus regulates metabolic rewiring and enhances proteostasis to promote reprogramming
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Cell Reports
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2020
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32, 107877, July 14, 2020
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Pingxin Sun,Guanyu Zhang,Xiaohui Su,Caixia Jin,Bing Yu,Xinlu Yu,Zhuman Lv,Haoxin Ma,,Wanguo Wei,and Wenlin Li
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Maintenance of Primary Hepatocyte Functions In Vitro by Inhibiting Mechanical Tension-Induced YAP Activation
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Cell Reports
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2019
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29(10):3212-3222.e4
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Chang Liu#, Xu Hu#, Yawen Li, Wenjie Lu, Wenlin Li, Nan Cao, Saiyong Zhu, Jinke Cheng, Sheng Ding*,
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Conversion of Mouse Fibroblasts into Oligodendrocyte Progenitor Like Cells through a Chemical Approach
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Journal of Molecular Cell Biology
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2018
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11(6):489-495
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Zhu Saiyong, Russ Holger A., Wang Xiaojing,, Ma Tianhua, Xu Tao, Tang Shibing, Hebrok Matthias, and Ding Sheng
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Human pancreatic beta-like cells converted from fibroblasts
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Nature Communications
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2016
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7:10080
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Xie Fei, Gong Kerui, Li Ke,, Chang Judy C., Jiang Shizhong, Ye Lin, Wang Jiaming, Tan Yuting, and Kan Yuet-Wai
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Reversible immortalization enables seamless transdifferentiation of primary fibroblasts into other lineage cells
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Stem Cells & Development
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2016
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25 (16):1243-1248
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Li Ke, Kong Yan,, Xie Fei, Liu Peng, Xu Shaohua
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Differentiation of pluripotent stem cells for regenerative medicine
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Biochem. Biophys. Res. Commun.
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2016
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471(1):1-4
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, Lin Yuan-Hung, Sun Yujiao Jennifer, Zhu Saiyong, Zheng Jiashun, Liu Kai, Cao Nan, Li Ke, Huang Yadong, and Ding Sheng
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Pharmacological Reprogramming of Fibroblasts into Neural Stem Cells by Signaling-Directed Transcriptional Activation
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Cell Stem Cell
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2016
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18 (5):653-667
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Cao Nan, Huang Yu, Zheng Jiashun, Spencer C. Ian, Zhang Yu, Fu Ji-Dong, Nei Baoming, Xie Min,, Wang Haixia, Ma Tianhua, Xu Tao, Shi Guilai, Srivastava Deepak and Ding Sheng
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Conversion of Human Fibroblasts into Functional Cardiomyocytes by Small Molecules
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Science
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2016
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352 (6290):1216-1220
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, Li Ke#, Xie Min, and Ding Sheng
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Chemical Approaches to Controlling Cell Fate
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Principles of Developmental Genetics, 2nd Edition
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2014
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59-76
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Zhu Saiyong, Ambasudhan Rajesh, Sun Woong, Kim Hyun Jung, Talantova Maria, Wang Xiaojing,, Zhang Yu, Laurent Timothy, Parker James, Kim Han-Seop, Zaremba Jeffrey D, Saleem Sofiyan, Sanz-Blasco Sara, Masliah Eliezer, McKercher Scott R, Cho Yee Sook, Lipton Stuart A, Kim Janghwan and Ding Sheng.
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Small Molecules Enable Oct4-Mediated Direct Reprogramming into Expandable Human Neural Stem Cells
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Cell Research
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2014
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24 (1):126-129
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Xu Tao#,, Laurent Timothy, Xie Min, and Ding Sheng
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Concise review: Chemical Approaches for Modulating Lineage-Specific Stem Cells and Progenitors
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Stem Cells Translational Medicine
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2013
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2 (5): 355-361
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Tong Xiajing, Li Qianjin, DuanYimin, Liu Ningning,, and Zhou Jinqiu
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Est1 protects telomeres and inhibits subtelomeric Y’-element recombination
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Molecular & Cellular Biology
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2011
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31(6):1263-1274
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, Tong Xiajing#, Fu Xiaohong, Zhou BO, Wang Jianyong, Liao Xinhua,Li Qianjin, Shen Ning, Ding Jianping and Zhou Jinqiu
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Yeast telomerase subunit Est1p has guanine-quadruplex promoting activity that is required for telomere elongation
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Nature Structural & Molecular Biology
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2010
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17 (2):202-209
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Liao Xinhua,, Yang Cuiping, Xu Luxia, Zhou Jinqiu
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Characterization of recombinant Saccharomyces cerevisiae telomerase core enzyme purified from yeast
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Biochemical Journal
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2005
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390 (Pt 1):169-176
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