• 基本信息
    导师姓名： 李华婷 学科代码： 100201
    性别： 女 学科名称： 内科学
    培养单位： 附属第六人民医院 三级学科 内分泌与代谢病
    导师类型： 博士生导师 专业领域名称： 内科学 专业学位
    联系方式： huarting99@sjtu.edu.cn 专业领域代码： 105101
    邮编： 200233 邮箱地址： huarting99@sjtu.edu.cn
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    Clinical Science编委
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    2022YFA1004804基于多尺度因果的疾病预警和辅助诊疗科技部国家重点研发计划 2022-12~2027-11 560万元  课题负责人
    82022012糖尿病发病机制与诊疗新靶点国家自然科学基金优秀青年科学基金 2021-01~2023-12 120万元  课题负责人
    20191830成纤维细胞生长因子19在糖代谢中的作用机制研究上海交通大学医学院双百人计划 2019-10~2022-09 100万元  课题负责人
    81870598成纤维细胞生长因子21在运动调节血管周围脂肪组织功能中的作用机制研究国家自然科学基金面上项目 2019-01~2022-12 57万元  课题负责人
    /上海市临床重点专科建设项目 ——内分泌代谢科（“振龙头”类）上海市卫计委 2018-01~2020-12 2129.19万元  子课题负责人
    17PJ1407500成纤维细胞生长因子21在能量代谢适应性反应中的生理作用与分子机制上海市浦江人才计划 2017-07~2019-06 20万元  课题负责人
    2017YQ009成纤维细胞生长因子21在能量代谢适应性反应中的作用与机制研究上海市卫生系统优秀青年人才培养计划 2017-07~2020-06 30万元  课题负责人
    2017ZZ01013上海市重中之重临床医学中心和重点学科建设计划上海市卫计委 2017-06~2021-05 1500万元  子课题负责人
    81561128016采用生物标志物对2型糖尿病进行风险预测和转归评价的中澳联合转化研究国家自然科学基金国际(地区)合作与交流项目 2016-01~2020-12 350万元  课题参与人
    XJ2013035糖尿病相关血管病变的跨学科研究: 从分子机制到干预治疗香江学者计划 2014-03~2016-02 54万元  课题负责人
    13CG11成纤维细胞生长因子21参与非酒精性脂肪肝的病理生理机制和预警价值研究上海市教委晨光计划 2014-01~2016-12 6万元  课题负责人
    13QA1402900成纤维细胞生长因子21 在非酒精性脂肪肝发生发展中的分子机制和临床研究上海市科委青年科技启明星计划 2013-07~2015-06 20万元  课题负责人
    81200292成纤维细胞生长因子21 在急性肝损伤中变化的机制和作用研究国家自然科学基金青年项目 2013-01~2015-12 23万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Leung H, Long X, Ni Y, Qian L, Nychas E, Siliceo SL, Pohl D, Hanhineva K, Liu Y, Xu A, Nielsen HB, Belda E, Clément K, Loomba R,, Jia W, Panagiotou G.   Risk assessment with gut microbiome and metabolite markers in NAFLD development.  Science Translational Medicine  2022  14(648):eabk0855 
    Liu D, Wu L, Gao Q, Long X, Hou X, Qian L, Ni J, Fang Q,, Jia W  FGF21/adiponectin ratio predicts deterioration in glycemia: a 4.6-year prospective study in China.   Cardiovasc Diabetol.   2021  2021 Jul 28;20(1):157.  
    Jing Zhang, Yueqiong Ni, Lingling Qian, Qichen Fang, Tingting Zheng, Mingliang Zhang, Qiongmei Gao, Ying Zhang , Jiacheng Ni, Xuhong Hou, Yuqian Bao, Petia Kovatcheva-Datchary, Aimin Xu,, Gianni Panagiotou, Weiping Jia  Decreased Abundance of Akkermansia muciniphila Leads to the Impairment of Insulin Secretion and Glucose Homeostasis in Lean Type 2 Diabetes  Advanced Science  2021  2021 Jun 4;e2100536.  
    Dai L, Wu L,, Cai C, Wu Q, Kong H, Liu R, Wang X, Hou X, Liu Y, Long X, Wen Y, Lu L, Shen Y, Chen Y, Shen D, Yang X, Zou H, Sheng B, Jia W.  A deep learning system for detecting diabetic retinopathy across the disease spectrum  Nature Communications  2021  12(1):3242.  
    , Guangyu Wu, Qichen Fang, Mingliang Zhang, Xiaoyan Hui, Bin Sheng, Liang Wu, Yuqian Bao, Peng Li, Aimin Xu, Weiping Jia   Fibroblast growth factor 21 increases insulin sensitivity through specific expansion of subcutaneous fat.  Nature Communications  2018  9(1):272 
    Dai L, Fang R,, Hou X, Sheng B, Wu Q, Jia W  Clinical Report Guided Retinal Microaneurysm Detection With Multi-Sieving Deep Learning  IEEE Trans Med Imaging  2018  37(5):1149-1161 
    Wu L, Pan Q, Wu G, Qian L, Zhang J, Zhang L, Fang Q, Zang G, Wang Y, Lau G,, Jia W.  Diverse Changes of Circulating Fibroblast Growth Factor 21 Levels in Hepatitis B Virus-Related Diseases.  Scientific Reports  2017   7(1): 16482 
    Yin B,, Sheng B, Hou X, Chen Y, Wu W, Li P, Shen R, Bao Y, Jia W  Vessel extraction from non-fluorescein fundus images using orientation-aware detector.  Med Image Anal  2015  26(1):232-42. 
    Jianxin Dou,, Xiaojing Ma, Mingliang Zhang, Qichen Fang, Meiyun Nie, Yuqian Bao* and Weiping Jia,  Jianxin Dou, Huating Li, Xiaojing Ma, Mingliang Zhang, Qichen Fang, Meiyun Nie, Yuqian Bao* and Weiping Jia,  Cardiovasc Diabetol  2014  13: p. 74. 
    Guangyu Wu,, Mi Zhou, Qichen Fang, Yuqian Bao, Aimin Xu, and Weiping Jia  Mechanism and clinical evidence of lipocalin-2 and adipocyte fatty acid-binding protein linking obesity and atherosclerosis.  Diabetes Metab Res Rev  2014  30(6): p. 447-56 
    Guangyu Wu,, Qichen Fang, Shan Jiang, Lei Zhang, Jing Zhang, Xuhong Hou, Junxi Lu, Yuqian Bao, Aimin Xu, and Weiping Jia  Elevated circulating lipocalin-2 levels independently predict incident cardiovascular events in men in a population-based cohort.   Arterioscler Thromb Vasc Biol  2014  34(11): p. 2457-64 
    Dewei Ye, Yudong Wang,, Weiping Jia, Kwan Man, Chung Mau Lo, Yu Wang, Karen S.L. Lam, and Aimin Xu  Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1alpha-mediated antioxidant capacity in mice.   Hepatology  2014  60(3): p. 977-89 
    Qichen Fang, Wenjing Yang,, Wenxiu Hu, Lihui Chen, Shan Jiang, Kun Dong, Qianqian Song, Chen Wang, Shuo Chen, Feng Liu, Weiping Jia  Negative Regulation of DsbA-L Gene Expression by the Transcription Factor Sp1.   Diabetes  2014  63(12): p. 4165-71 
    , Kun Dong, Qichen Fang, Xuhong Hou, Mi Zhou, Yuqian Bao, Kunsan Xiang, Aimin Xu, Weiping Jia  High serum level of fibroblast growth factor 21 is an independent predictor of non-alcoholic fatty liver disease: A 3-year prospective study in China.   J Hepatol   2013  58(3):557-63 
    , Jing Zhang, Weiping Jia  Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology  Front Med.  2013  7(1):25-30 
    Qichen Fang,, Qianqian Song, Wenjing Yang, Xuhong Hou, Xiaojing Ma, Junxi Lu, Aimin Xu, Weiping Jia  Serum fibroblast growth factor 19 levels are decreased in Chinese subjects with impaired fasting glucose and inversely associated with fasting plasma glucose levels.  Diabetes Care   2013  36(9):2810-4 
    , Zhanguo Gao, Jin Zhang, Xin Ye, Aimin Xu, Jianping Ye, Weiping Jia  Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3  Diabetes   2012  61(4):797-806 
    Dewei Ye, Francois Y.L. Li, Karen S.L. Lam,, Weiping Jia, Yu Wang, Kwan Man, Chung Mau Lo, Xiaokun Li, Aimin Xu  Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice  Gut  2012  61(7):1058-1067 
    , Qichen Fang, Fei Gao, Jia Fan, Jian Zhou, Xiaoying Wang, Xiaoping Pan, Yuqian Bao, Kunsan Xiang, Aimin Xu, Weiping Jia  Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride.   J Hepatol  2010  53(5):934-40 
    Yuqian Bao, Xiaojing Ma,, Mi Zhou, Cheng Hu, Junling Tang, Kunsan Xiang, Weiping Jia  Glycated haemoglobin A1c for diagnosing diabetes in Chinese population: cross sectional epidemiological survey.  BMJ   2010  340:c2249 
    , Yuqian Bao, Aimin Xu, Xiaoping Pan, Junxi Lu, Haiya Wu, Huijuan Lu, Kunsan Xiang, Weiping Jia  Serum Fibroblast Growth Factor 21 is Associated with Adverse Lipid Profiles and γ-glutamyltransferase but not Insulin Sensitivity in Chinese Subjects with and without Impaired Glucose Regulation.  J Clin Endocrinol Metab   2009  94(6):2151-6 
    Yuqian Bao, Junxi Lu, Cheng Wang, Ming Yang,, Xiaoyan Zhang, Jiehua Zhu, Huijuan Lu, Weiping Jia, Kunsan Xiang.   Optimal waist circumference cutoffs for abdominal obesity in Chinese  Atherosclerosis  2008  201(2):378-84