- 基本信息
|
导师姓名：
|
李金宝
|
学科代码：
|
100217
|
|
|
性别：
|
男
|
学科名称：
|
麻醉学
|
|
培养单位：
|
附属第一人民医院
|
三级学科
|
|
|
导师类型：
|
博士生导师
|
专业领域名称：
|
麻醉学 专业学位
|
|
联系方式：
|
|
专业领域代码：
|
105118
|
|
邮编：
|
|
邮箱地址：
|
lijinbaoshanghai@163.com
|
- 研究方向 (点击浏览详细信息)
- 社会任职
| |
|
上海市医学会麻醉科专科分会委员兼秘书长
|
|
中华医学会麻醉学分会危重病学组副组长
|
|
中国医师协会麻醉科医师分会 委员
|
|
中国研究型医院学会麻醉专业委员会 常委
|
|
中华医学会麻醉学专业委员会老年人麻醉学组委员
|
|
中国神经科学学会麻醉与脑功能分会常委兼秘书长
|
|
中国药理学会麻醉药理专业委员会 委员
|
|
上海市医师协会麻醉科医师分会 副会长
|
|
中国高等医学教育理事会麻醉学教育研究会 常委兼秘书长
|
|
中国心胸血管麻醉学会胸科麻醉分会副主任委员
|
|
上海市医师协会麻醉科医师分会 委员
|
|
中国研究型医院学会休克与脓毒症分会 常委
|
|
中国心胸血管麻醉学会围术期器官保护分会副主任委员
|
|
上海市医学会麻醉科专科分会老年麻醉学组 委员兼组长
|
- 科研项目
| 8227080924 | Itaconate烷基化修饰AIM2诱导树突状细胞PANoptosis促进脓毒症免疫抑 制的机制研究 | 国家自然科学基金 |
2023-01~2026-12
|
55万元
| 课题负责人 |
| 81971813 | mtDNA通过STING调控IRG1-itaconate轴在脓毒症DC功能障碍中的作用和机制研究 | 国家自然科学基金面上项目 |
2020-01~2023-12
|
54万元
| 课题负责人 |
| 临床研究创新研究项目 | 连续腰丛神经阻滞联合右美托咪定对老年髋部骨折患者术后谵妄的影响：前瞻性、随机对照研究 | 上海市第一人民医院 |
2018-09~2020-12
|
60万元
| 课题负责人 |
| 201708 | KLF14通过调控糖代谢介导脓毒症时单核巨噬细胞功能障碍的研究 | 上海交通大学附属第一人民医院 |
2017-07~2019-06
|
15万元
| 课题负责人 |
| 201605 | 清道夫受体SR-BI介导脓毒症时DC 功能障碍的研究 | 上海交通大学附属第一人民医院 |
2016-06~2018-05
|
8万元
| 课题负责人 |
| 81571877 | Rhbdd3通过调控糖代谢介导脓毒症时DC功能障碍的研究 | 国家自然科学基金面上项目 |
2016-01~2019-12
|
68.4万元
| 课题负责人 |
- 学术论文
|
Yuan Y, Fan G, Liu L, Liu Y, Zhang T, Liu P, Tu Q, Zhang X, Luo S, Yao L, Chen F,
|
The Transcription Factor KLF14 Regulates Macrophage Glycolysis and Immune Function by Inhibiting HK2 in sepsis
|
Cell Mol Immunol.
|
2022
|
2022 May;19(5):650
|
|
Peng Xu, Shaobo Zhang, Lili Tan, Lei Wang, Zhongwei Yang and Jinbao Li
|
Local Anesthetic Ropivacaine Exhibits Therapeutic Effects in Cancers
|
Frontiers in Oncology.
|
2022
|
doi: 10.3389/fonc.2022.836882
|
|
Liu P, Wang Y, Zhang R, Xu L,, Mu D
|
Propofol modulates inhibitory inputs in paraventricular thalamic nucleus of mice
|
Neuroscience Letters
|
2021
|
2021;756:135950
|
|
Cao Y, Chen X, Liu Y, Zhang X, Zou Y,
|
PIM1 inhibition attenuated endotoxin?induced acute lung injury through modulating ELK3/ICAM1 axis on pulmonary microvascular endothelial cells
|
Inflamm Res.
|
2021
|
2021;70(1):89-98
|
|
Tu Q , Zhu Y, Yuan Y, Guo L, Liu L, Yao L, Zou Y,, Chen F
|
Gypenosides Inhibit Inflammatory Response and Apoptosis of Endothelial and Epithelial Cells in LPS-Induced ALI: A Study Based on Bioinformatic Analysis and in vivo/vitro Experiments
|
Drug Des Devel Ther.
|
2021
|
2021;15:289-303
|
|
Yao L, Xuan Y, Zhang H, Yang B, Ma X, Wang T, Meng T, Sun W, Wei H, Ma X,, Zhang B
|
Reciprocal REGγ-mTORC1 regulation promotes glycolytic metabolism in hepatocellular carcinoma
|
Oncogene
|
2021
|
2021;40(3):677-692.
|
|
Zheng Liu, Kezhe Tan, Lan Bu,Lulong Bo, Wen Ni, Miaomiao Fei, Fang Chen, Xiaoming Deng,
|
Tim4 regulates NALP3 inflammasome expression and activity during monocyte/macrophage dysfunction in septic shock patients
|
Burns
|
2020
|
46(3):652-662
|
|
Han Shao, Xu Zhang, Linxing Ruan,, Feng Chen, Long Guo, Jiali Zhu
|
Methane suppressed dendritic cells activation in trinitrobenzene sulfonic acid induced colitis
|
Int Immunopharmacol
|
2020
|
3;82:106360.
|
|
Xinyi Zhang,Yun Zou,Yuqi Liu,Yumeng Cao, Jiali Zhu,Jianhai Zhang,Xia Chen,Rui Zhanga,
|
Inhibition of PIM1 kinase attenuates bleomycin-induced pulmonary fibrosis in mice by modulating the ZEB1/E-cadherin pathway in alveolar epithelial cells
|
Molecular Immunology
|
2020
|
125 (2020) 15–22
|
|
Lina Huang, Guanghui An, Shan You, Shiwei Huang,
|
Application of an education model using the WeChat public platform in the standardized training of anesthesiology residents
|
Ann Palliat Med
|
2020
|
9(4):1643-1647
|
|
Xuejiao Zhu, Bing Wang, Xinyi Zhang, Xia Chen, Jiali Zhu, Yun Zou,
|
Alpha-linolenic acid protects against lipopolysaccharide-induced acute lung injury through anti-inflammatory and anti-oxidative pathways
|
Microb Pathog
|
2020
|
18;142:104077
|
|
Wang J, Cao Y, Liu Y, Zhang X, Ji F,, Zou Y
|
PIM1 inhibitor SMI-4a attenuated lipopolysaccharide-induced acute lung injury through suppressing macrophage inflammatory responses via modulating p65 phosphorylation
|
Int Immunopharmacol
|
2019
|
73:568-574
|
|
Zou Y, Cao Y, Liu Y, Zhang X,, Xiong Y
|
The role of dorsal root ganglia PIM1 in peripheral nerve injury-induced neuropathic pain
|
Neurosci Lett
|
2019
|
23;709:134375
|
|
Wang F, Fu X, Wu X, Zhang J, Zhu J, Zou Y,
|
Bone marrow derived M2 macrophages protected against lipopolysaccharide-induced acute lung injury through inhibiting oxidative stress and inflammation by modulating neutrophils and T lymphocytes responses
|
Int Immunopharmacol
|
2018
|
61:162-168.
|
|
Zou Y, Bao S, Wang F, Guo L, Zhu J, Wang J, Deng X,
|
FN14 Blockade on Pulmonary Microvascular Endothelial Cells Improves the Outcome of Sepsis- Induced Acute Lung Injury.
|
Shock
|
2017
|
doi: 10.1097/SHK. 0000000000000915
|
|
Zhang Y, Zhu J, Guo L, Zou Y, Wang F, Shao H,, Deng X.
|
Cholecystokinin protects mouse liver against ischemia and reperfusion injury.
|
Int Immunopharmacol
|
2017
|
48:180-186
|
|
Zhu X, Zou Y, Wang B, Zhu J, Chen Y, Wang L,, Deng X.
|
Blockade of CXC chemokine receptor 3 on endothelial cells protects against sepsis-induced acute lung injury
|
J Surg Res.
|
2016
|
204(2):288-96
|
|
Bao S, Zou Y, Wang B, Li Y, Zhu J, Luo Y,
|
Ginsenoside Rg1 improves lipopolysaccharide-induced acute lung injury by inhibiting inflammatory responses and modulating infiltration of M2 macrophages
|
Int Immunopharmacol
|
2015
|
2015;28(1):429-34
|
|
Wang JF,, Zhao YJ, Yi WJ, Bian JJ, Wan XJ, Zhu KM, Deng XM.
|
Up-regulation of programmed cell death 1 ligand 1 on neutrophils may be involved in sepsis-induced immunosuppression: an animal study and a prospective case-control study.
|
Anesthesiology
|
2015
|
2015;122(4):852-63
|
|
Zou Y, Tao T, Tian Y, Zhu J, Cao L, Deng X,
|
Ginsenoside Rg1 improves survival in a murine model of polymicrobial sepsis by suppressing the inflammatory response and apoptosis of lymphocytes
|
J Surg Res
|
2013
|
2013 ;183(2):760-6
|
|
Zhu J, Wang J, Sheng Y, Zou Y, Bo L, Wang F, Lou J, Fan X, Bao R, Wu Y, Chen F, Deng X,
|
Baicalin improves survival in a murine model of polymicrobial sepsis via suppressing inflammatory response and lymphocyte apoptosis
|
PLoS One
|
2012
|
2012;7(5):e35523
|
|
, Zhang Y, Lou J, Zhu J, He M, Deng X, Cai Z.
|
Neutralisation of peritoneal IL-17A markedly improves the prognosis of severe septic mice by decreasing neutrophil infiltration and proinflammatory cytokines
|
PLoS One
|
2012
|
2012;7(10):e46506
|
|
, Xiong YC, Wang XL, Fan XH, Li Y, Xu H, Ma Y, Deng XM.
|
An evaluation of the TruView EVO2 laryngoscope.
|
Anaesthesia
|
2007
|
2007;62(9):940-3.
|
|