- 基本信息
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导师姓名：
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谷平
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学科代码：
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100212
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性别：
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男
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学科名称：
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眼科学
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培养单位：
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附属第九人民医院
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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联系方式：
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guping2009@126.com
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专业领域代码：
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邮编：
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200011
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邮箱地址：
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guping2009@126.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中华医学会医师协会眼科学分会视觉生理学组委员
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上海市医学会眼科专科分会视觉研究学组委员
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海峡两岸医药卫生交流协会眼科专委会眼干细胞学组委员
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中华医学会眼科学分会视觉生理学组委员
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国际临床视觉电生理学会委员
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- 科研项目
| 82271123 | 降钙素基因相关肽介导三叉神经元和巨噬细胞协同促骨髓间充质干细胞成骨分化在眼眶骨缺损修复中的作用及机制 | 国家自然科学基金面上项目 |
2023-01~2026-12
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52万元
| 课题负责人 |
| 2022YFA1105502 | 干细胞来源视网膜节细胞及配伍细胞制备和移植方案研究 | 十四五国家重点研发计划“干细胞研究与器官修复专项”课题 |
2022-12~2027-11
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700万元
| 课题负责人 |
| 82071004 | CircRNA-0879/miR-3594-5p/TRPV1/CGRP轴介导的骨髓间充质干细胞和三叉神经元的协同作用在诱导新骨修复眼眶骨缺损中的作用及机制 | 国家自然科学基金面上项目 |
2021-01~2024-12
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55万元
| 课题负责人 |
| 20161316 | 钙磷涂层镁合金修复眼眶骨缺损的作用及机制 | 上海交通大学医学院双百人计划（连续资助） |
2019-07~2022-06
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115万元
| 课题负责人 |
| 81870687 | CircRNA-vgll3介导的脂肪间充质干细胞修复眼眶骨缺损及其作用机制研究 | 国家自然科学基金面上项目 |
2019-01~2022-12
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57万元
| 课题负责人 |
| 沪交医人【2016】13号 | 《聚癸二酸二甘油酯马来酸酯支架复合生长因子在间充质干细胞修复眼眶骨中的作用及其机制研究》 | 上海交通大学医学院双百人计划 |
2016-07~2019-06
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100万元
| 课题负责人 |
| 81570883 | 《miR-135介导的骨髓基质干细胞对眼眶骨缺损修复重建及调控机制研究》 | 国家自然科学基金面上项目 |
2016-01~2019-12
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79.2万元
| 课题负责人 |
| 14JC1493103 | 《PSeD马来酸酯微纳结构支架复合生长因子修复眼眶骨的研究》 | 上海市科委基础重点项目 |
2014-09~2017-08
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20万元
| 课题负责人 |
| 14DZ0510202 | 《OLED显示器产品的视觉安全性医学前期研究》 | 上海市科委科技攻关项目 |
2014-07~2016-06
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30万元
| 课题负责人 |
| 13DZ0500303 | 《有机发光新型显示器的视觉安全性及舒适性研究》 | 上海市科委标准专项 |
2013-07~2016-06
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37.5万元
| 课题负责人 |
| [2011]1568 | 《微小RNA影响视网膜干细胞自我更新和分化潜能的研究》 | 教育部留学回国人员科研基金 |
2012-01~2014-12
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3.4万元
| 课题负责人 |
| 81070737 | 《microRNA-9对视网膜干细胞增殖分化的影响及其作用机制的研究》 | 国家自然科学基金面上项目 |
2011-01~2013-12
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35万元
| 课题负责人 |
| 11YZ47 | 《微小RNA影响视网膜干细胞增殖和分化的基础研究》 | 上海市教委科研创新项目 |
2011-01~2013-12
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8万元
| 课题负责人 |
- 学术论文
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Ni N, Ge M, Huang R, Zhang D, Lin H, Ju Y, Tang Z, Gao H, Zhou H*, Chen Y*, Gu P*(谷平)
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Thermodynamic 2D Silicene for Sequential and Multistage Bone Regeneration.
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Adv Healthc Mater.
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2023
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2023 Jan 23:e2203107.
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Tang Z, Liu Y, Xiang H, Dai X, Huang X, Ju Y, Ni N, Huang R, Gao H, Zhang J, Fan X, Su Y*, Chen Y*,
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Bifunctional MXene-Augmented Retinal Progenitor Cell Transplantation for Retinal Degeneration.
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Adv Sci.
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2023
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2023 Jun 28:e2302747.
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Gao H, Chen M, Liu Y, Zhang D, Shen J, Ni N, Tang Z, Ju Y, Dai X, Zhuang A, Wang Z, Chen Q*, Fan X*, Liu Z*,
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Injectable anti-inflammatory supramolecular nanofiber hydrogel to promote anti-VEGF therapy in age-related macular degeneration treatment.
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Advanced Materials
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2023
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2023 Jan;35(2):e2204994.
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Huo M, Tang Z, Wang L, Zhang L, Guo H, Chen Y,, Shi J*
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Magnesium hexacyanoferrate nanocatalyst attenuates chemodrug-induced cardiotoxicity through ferromodulation-driven anti-apoptosis. Nature Communications
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Nature Communications
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2022
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2022 Dec 15; 13(1):7778.
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Tang Z, Ju Y, Dai X , Ni N, Liu Y, Zhang D, Gao H, Sun H, Zhang J*,
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HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration
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Redox Biology
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2021
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43:101971
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Sun N, Dou X *, Tang Z, Zhang D, Ni N, Wang J, Gao H, Ju Y, Dai X, Zhao C,, Ji J *, Feng C *
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Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway
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Bioactive Materials
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2021
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6: 990–997
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Yang Y, Ju Y, Li Y, Yin L, Chen L,, Zhang J*
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Transparent nanostructured BiVO4 double films with blue-light shielding capabilities to prevent damage to ARPE-19 cells
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ACS Appl Mater Interfaces
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2020
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12(18):20797-20805
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Zhang D, Ni N, Su Y, Miao H, Tang Z, Ji Y, Wang Y, Gao H, Ju Y, Sun N, Sun H, Yuan G, Wang Y, Zhou H, Huang H*,, Fan X*
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Targeting Local Osteogenic and Ancillary Cells by Mechanobiologically Optimized Mg Scaffolds for Orbital Bone Reconstruction in Canines
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ACS Appl Mater Interfaces
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2020
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12(25):27889-27904
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Zhang D, Ni N, Wang Y, Tang Z, Gao H, Ju Y, Sun N, He X,, Fan X*
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CircRNA-vgll3 promotes osteogenic differentiation of adipose-derived mesenchymal stem cells via modulating miRNA-dependent integrin α5 expression
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Cell Death and Differentiation
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2020
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28(1):283-302
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Jiang F, Tang Z, Zhang Y, Ju Y, Gao H, Sun N, Liu F,, Zhang W*.
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Enhanced proliferation and differentiation of retinal progenitor cells through a self-healing injectable hydrogel.
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Biomater Sci.
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2019
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2019 Mar 25. doi: 10.1039/c8bm01579a
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Tang Z, Jiang F, Zhang Y, Zhang Y, YuanYang, Huang X, Wang Y, Zhang D, Ni N, Liu F, Luo M, Fan X*, Zhang W*,
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Mussel-inspired injectable hydrogel and its counterpart for actuating proliferation and neuronal differentiation of retinal progenitor cells.
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Biomaterials
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2019
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194:57-72
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Wang Y, Zhang D, Zhang Y, Ni N, Tang Z, Bai Z, Shen B, Sun H*,
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Insulin-like growth factor-1 regulation of retinal progenitor cell proliferation and differentiation.
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Cell Cycle
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2018
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17(4):515-526
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Ji J, Zhang D, Wei W, Shen B, Zhang Y, Wang Y, Tang Z, Ni N, Sun H, Liu J, Fan X,
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Decellularized matrix of adipose-derived mesenchymal stromal cells enhanced retinal progenitor cell proliferation via the Akt/Erk pathway and neuronal differentiation.
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Cytotherapy
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2018
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20 (1): 74-86
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Zhang D, Shen B, Zhang Y, Ni N, Wang Y, Fan X, Sun H*,
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Betacellulin regulates the proliferation and differentiation of retinal progenitor cells in vitro.
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J Cell Mol Med
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2018
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22(1): 330-345
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Deng Y, Guo T, Li J, Guo L,, Fan X*.
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Repair of calvarial bone defect using Jarid1a-knockdown bone mesenchymal stem cells in rats.
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Tissue Eng Part A
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2018
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24:711-718
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Wang Y, Zhang D, Tang Z, Zhang Y, Gao H, Ni N, Shen B, Sun H*,
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REST, regulated by RA through miR-29a and the proteasome pathway, plays a crucial role in RPC proliferation and differentiation.
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Cell Death & Disease
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2018
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9(5):444
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Wang Y, Zhang D, Shen B, Zhang Y,
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Stem/progenitor cells and biodegradable scaffolds in the treatment of retinal degenerative diseases.
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Curr Stem Cell Res Ther
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2018
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13(3):160-173
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Ding Y, Su Y, Lv Z, Sun H, Bi X, Lu L, Zhou H, You Z, Wang Y, Ruan J*,, Fan X*
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Poly (fumaroyl bioxirane) maleate: A potential functional scaffold for bone regeneration.
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Mater Sci Eng C Mater Biol Appl
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2017
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76:249-259
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Tang Z, Zhang Y, Wang Y, Zhang D, Shen B, Luo M*,
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Progress of stem/progenitor cell-based therapy for retinal degeneration
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J Transl Med
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2017
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15(1):99 doi: 10.1186/s12967-017-1183-y
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Wei W, Li J, Chen S, Chen M, Xie Q, Sun H, Ruan J, Zhou H, Bi X, Zhuang A, You Z*,, Fan X*
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In vitro osteogenic induction of bone marrow mesenchymal stem cells with decellularized matrix derived from human adipose stem cells and in vivo implantation for bone regeneration
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Journal of Materials Chemistry B
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2017
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5:2468 - 2482
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Zhang W, Zhuang A,, Zhou H*, Fan X*
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A Review of the Three-Dimensional Cell Culture Technique: Approaches,Advantages and Applications
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Current Stem Cell Research & Therapy
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2016
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11: 370-380
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Wang Z, Lin M, Xie Q, Sun H, Huang Y, Zhang D, Yu Z, Bi X, Chen J, Wang J, Shi W,, Fan X*
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Electrospun SF/PLCL nanofibrous scaffolds for bone regeneration
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International Journal of Nanomedicine
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2016
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11：1483–1500
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Ni N, Ji Ji, Chen S, Zhang D, Wang Z, Shen B, Guo C, Zhang Y, Wang S, Fan X, You Z*, Luo M*,
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Poly(1,3-propylene sebacate) and Poly(sebacoyl diglyceride): a Pair of Potential Polymers for the Proliferation and Differentiation of Retinal Progenitor Cells
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Macromolecular Bioscience
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2016
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doi: 10.1002/mabi.201600058
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Fang S, Huang Y, Zhong S, Zhang Y, Liu L, Wang Y,, Zhou H*, Fan X*
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IL-17A Promotes RANTES Expression, But Not IL-16, in Orbital Fibroblasts Via CD40-CD40L Combination in Thyroid-Associated Ophthalmopathy
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Invest Ophthalmol Vis Sci
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2016
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57(14):6123-6133
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Xie Q , Wang Z, Zhou H, Yu Z, Huang Y, Sun H, Bi X, Wang Y, Shi W,, Fan X*
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The role of miR-135-modified adipose-derived mesenchymal stem cells in bone regeneration
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Biomaterials
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2016
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75: 279-294
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Ruan J, Wang X, Yu Z, Wang Z, Xie Q, Zhang D, Huang Y, Zhou H, Bi X, Xiao C,, Fan X*
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Enhanced Physiochemical and Mechanical Performance of Chitosan-grafted Graphene Oxide for Superior Osteoinductivity
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Advanced Functional Materials
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2016
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26: 1085-1097
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Xie Q, Wang Z, Huang Y, Bi X, Zhoua H, Lin M, Yu Z, Wang Y, Ni N, Sun J, Wu S, You Z, Guo C, Sun H, Wang Y,, Fan X*.
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Characterization of human ethmoid sinus mucosa derived mesenchymal stem cells (hESMSCs) and the application of hESMSCs cell sheets in bone regeneration.
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Biomaterials
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2015
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66: 67-82,
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Zhang D, Ni N, Chen J, Yao Q, Shen B, Zhang Y, Zhu M, Wang Z, Ruan J, Wang J, Mo X, Shi W, Ji J*, Fan X*,, 2015 (IF=5.578)
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Electrospun SF/PLCL nanofibrous membrane: a potential scaffold for retinal progenitor cell proliferation and differentiation.
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Scientific Reports
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2015
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doi: 10.1038
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Wang Z, Xie Q , Yu Z, Zhou H, Huang Y, Bi X, Wang Y, Shi W, Sun H,, Fan X*.
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A regulatory loop containing miR-26a, GSK3β and C/EBPα regulates the osteogenesis of human adipose-derived mesenchymal stem cells.
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Scientific Reports
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2015
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5:15280. doi: 10.1038/srep15280,
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Deng Y, Zhou HF, Yan CX, Bi XP,, Fan X*.
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In vitro osteogenic induction of BMSCs with encapsulated gene modified BMSCs and in vivo implantation for orbital bone repair.
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Tissue Eng Part A
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2014
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20： 2019-2029,
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Ni N, Zhang D, Xie Q, Chen J, Wang Z, Deng Y, Wen X, Zhu M, Ji J, Fan X*, Luo M*,
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Effects of let-7b and TLX on the proliferation and differentiation of retinal progenitor cells in vitro.
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Scientific Reports
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2014
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4:6671.
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Hu Y, Luo M, Ni N, Deng Y, Xia J, Chen J, Ji J, Zhou X, Fan X*,
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Reciprocal actions of microRNA-9 and TLX in the proliferation and differentiation of retinal progenitor cells.
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Stem Cells and Development
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2014
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23(22): 2771-81,
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Xie Q, Wang Z, Bi X, Zhou H, Wang Y,, Fan X*.
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Effects of miR-31 on the osteogenesis of human mesenchymal stem cells.
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Biochemical and Biophysical Research Communications
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2014
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446(1):98-104,
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Deng Y, Zhou HF,, Fan X*.
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Repair of Canine Medial Orbital Bone Defects with miR-31-modified Bone Marrow Mesenchymal Stem Cells.
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Invest Ophthalmol Vis Sci
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2014
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55(9): 6016-6023
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Che X, He F, Deng Y, Xu S, Fan X,, Wang Z*.
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HIV-1 Tat-Mediated Apoptosis in Human Blood-Retinal Barrier-Associated Cells.
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PLoS One
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2014
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9(4): e95420,
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Xia J, Luo M, Ni N, Chen J, Hu Y, Deng Y, Ji J, Zhou J, Fan X*,
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Bone marrow mesenchymal stem cells stimulate proliferation and neuronal differentiation of retinal progenitor cells.
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PLoS One
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2013
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8(9): e76157,
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Hu YM, Ji J, Xia J, Zhao PQ, Fan XQ, Wang ZL, Zhou XJ, Luo M*,
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An in vitro comparison study: the effects of fetal bovine serum concentration on retinal progenitor cell multipotentiality.
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Neuroscience Letters
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2013
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534: 90-95
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Deng Y, Zhou H, Zou D, Xie Q, Bi X,, Fan X*
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The role of miR-31-modified adipose tissue-derived stem cells in repairing rat critical-sized calvarial defects.
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Biomaterials
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2013
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34: 6717-6728
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Deng Y, Wu S, Zhou H, Bi X, Wang Y, Zhao P, Hu Y,, Fan X*.
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Effects of a miR-31, Runx2 and Satb2 regulatory loop on the osteogenic differentiation of bone marrow mesenchymal stem cells.
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Stem Cells and Development
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2013
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22(16): 2278-86,
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Zhao PQ, Deng Y,, Wang YF, Zhou HF, Hu YM, Chen P, Fan XQ*.
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Insulin-like growth factor 1 promotes the proliferation and adipogenesis of orbital adipose-derived stromal cells in thyroid-associated ophthalmopathy.
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Experimental Eye Research
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2013
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107: 65-73,
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