- 基本信息
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导师姓名：
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陈天璐
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学科代码：
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100201
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性别：
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女
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学科名称：
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内科学
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培养单位：
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附属第六人民医院
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三级学科
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内分泌与代谢病
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导师类型：
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博士生导师
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专业领域名称：
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联系方式：
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专业领域代码：
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邮编：
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邮箱地址：
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chentianlu@sjtu.edu.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中国生物物理学会代谢组学分会会员
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上海市生物信息学会会员
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欧盟玛丽居里学者
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- 科研项目
| 31972935 | 基于“代谢物组-微生物组深度关联分析策略”的2型糖尿病进展模式和 | 国家自然科学基金委 |
2020-01~2023-12
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56万元
| 课题负责人 |
| 2019YFA0802300 | 不同发育阶段肠道菌群特征及其对发育的影响 子课题 | 科技部 |
2019-12~2024-11
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1700万元
| 课题参与人 |
| 18DZ2294100 | 上海市重大疾病临床生物样本实体库专业技术服务平台 | 上海市研发平台专项 |
2018-04~2021-03
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100万元
| 课题参与人 |
| 31501079 | 基于“半聚焦”代谢组学策略的主要消化系统肿瘤共有和特有代谢模式研究 | 国家自然科学基金委 |
2016-01~2018-12
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20万元
| 课题负责人 |
| 292183 | Cognitive-Networks-Enabled Transnational Proactive Healthcare (CoNHealth) | 欧盟 |
2012-04~2016-03
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60万元
| 课题负责人 |
| 10ZR1414800 | 基于代谢组学信息融合的三种恶性肿瘤特征代谢物组研究 | 上海市科委 |
2010-04~2012-03
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10万元
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| 2007CB914700 | 代谢性疾病的蛋白质功能与代谢组学研究 | 国家科技部 |
2009-01~2011-12
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1500万元
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- 学术论文
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Lepeng Zhou, Wen Qiu, Jie Wang, Aihua Zhao, Chuhui Zhou, Tao Sun, Ziyu Xiong, Peihua Cao, Wei Shen, Jingfen Chen, Xiaolu Lai, Liuhong Zhao, Meng Li, Feng Qiu, Liping Huang, Yanhong Yu, Hongwei Zhou, Wei Jia, Yan Liao, Ravi Retnakaran, Daniel Krewski, Shi Wu Wen, Jose C Clemente,, Rihua Xie, Yan He
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Effects of vaginal microbiota transfer on the neurodevelopment and microbiome of cesarean-born infants: A blinded randomized controlled trial
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Cell host & microbe
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2023
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31(7): 1232
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Wu Lirong, Zhao Mingliang, Li Mengci, Guo Qihao, Ren Zhenxing, Zheng Xiaojiao,
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The clinical and mechanistic roles of bile acids in depression, Alzheimer's disease, and stroke
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Proteomics
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2022
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22(15-16):e2100324
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Sun Tao, Li Mengci, Yu Xiangtian, Liang Dandan, Xie Guoxiang, Sang Chao, Jiao Wei,,
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3MCor: an integrative web server for metabolome-microbiome-metadata correlation analysis
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Bioinformatics
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2021
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10.1093/bioinformatics/btab818
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Sang Chao, Wang Xiaoning, Zhou Kejun, Sun Tao, Bian Hua, Gao Xin, Wang Yixing, Zhang Hua, Jia Wei, Liu Ping, Xie Guoxiang,
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Bile acid profiles are distinct among patients with different etiologies of chronic liver disease
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Journal of Proteome Research
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2021
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20(5):2340-2351
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Xiaojiao Zheng,, Aihua Zhao, Zhangchi Ning, Junliang Kuang, Shouli Wang, Yijun You, Yuqian Bao, Xiaojing Ma, Haoyong Yu, Miao Jiang, Mengci Li, Xiaolong Han, Meilin Wei, Yitao Li, Kun Ge, Cynthia Rajani, Guoxiang Xie, Cheng Hu, Aiping Lu*, Weiping Jia,Wei Jia,
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Hyocholic acid species as novel biomarkers for metabolic disorders
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Nature Communications
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2021
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12:1487
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, Kejun Zhou, Tao Sun, Chao Sang, Wei Jia, Guoxiang Xie,
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Bile acid glycine:taurine ratios predict the progression of chronic liver disease
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Journal of Gastroenterology and Hepatology
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2021
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10.1111/jgh.15709
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Sang Chao, Hongmei Yan, Wah Kheong Chan, Xiaopeng Zhu, Tao Sun, Xinxia Chang, Mingfeng Xia, Xiaoyang Sun, Xiqi Hu, Xin Gao, Wei Jia, Hua Bian,, Guoxiang Xie
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Blood test markers to diagnose advanced fibrosis in Southeast Asian patients with non-alcoholic fatty liver disease
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Frontiers in Medicine
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2021
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8:637652
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Xiaojiao Zheng,, Runqiu Jiang, Aihua Zhao, Qing Wu, Junliang Kuang, Dongnan Sun, Zhenxing Ren, Mengci Li, Mingliang Zhao, Shouli Wang, Yuqian Bao, Huating Li, Cheng Hu, Bing Dong, Defa Li, Jiayu Wu, Jialin Xia, Xuemei Wang, Ke Lan, Cynthia Rajani, Guoxiang Xie, Aiping Lu, Weiping Jia, Changtao Jiang, Wei Jia
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Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism
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Cell Metabolism
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2021
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33(4): 791-803
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Xia Zhang, Yuping Yang, Juan Su, Xiaojiao Zheng, Chongchong Wang, Shaoqiu Chen, Jiajian Liu, Yingfang Lv, Shihao Fan, Aihua Zhao,, Wei Jia, Xiaoyan Wang
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Age-related compositional changes and correlations of gut microbiome, serum metabolome and immune factor in rats
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GeroScience
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2021
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43(2), 709-725
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Di Zhou, Wenjia Zhu, Tao Sun, Yang Wang, Yi Chi,, Jingchao Lin
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iMAP: A web server for metabolomics data integrative analysis
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Frontiers in Chemistry
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2021
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10.3389/fchem.2021.659656
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Dandan Liang, Quan Liu, Kejun Zhou, Wei Jia, Guoxiang Xie,
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IP4M: An integrated platform for mass spectrometry-based metabolomics data analysis
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BMC bioinformatics
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2020
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211(1): 444-459
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D.D. Liang, M.C. Li, R.M. Wei, J.Y. Wang, Y.T. Li, W. Jia,
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A Strategy for Inter-correlation Identification between Metabolome and Microbiome
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Analytical Chemistry
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2019
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91(22): 14424-14432
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Yitao Li, Xiaojiao Zheng, Wei Jia,
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MCEE 2.0 - more options and enhanced performance
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Analytical and Bioanalytical Chemistry
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2019
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10.1007/s00216-019-01874-3
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Yijun You, Dandan Liang, Runmin Wei, Mengci Li, Yitao Li, Jingye Wang, Xiaoyan Wang, Xiaojiao Zheng, Wei Jia,
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Evaluation of Metabolite-Microbe Correlation Detection Methods
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Analytical Biochemistry
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2019
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567(2019): 106-111
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, Yijun You, Guoxiang Xie, Xiaojiao Zheng, Aihua Zhao, Jiajian Liu, Qing Zhao, Shouli Wang, Fengjie Huang, Cynthia Rajani, Congcong Wang, Shaoqiu Chen, Yan Ni, Herbert Yu, Youping Deng, Xiaoyan Wang, and Wei Jia,
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Strategy for Association Study on Intestinal Microbiome and Brain Metabolome across Lifespan of Rats
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Analytical Chemistry
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2018
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90(4): 2475-2483
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Xiaojiao Zheng, Kejun Zhou, Yunjing Zhang, Xiaolong Han, Aihua Zhao, Jiajian Liu, Chun Qu, Kun Ge, Fengjie Huang, Brenda Hernande, Herbert Yu, Jun Panee,, Weiping Jia, and Wei Jia
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Food withdrawal alters the gut microbiota and metabolome in mice
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FASEB Journal
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2018
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32(9):4878-4888
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Rummin Wei, Jingye Wang, Mingming Du, Erik Jia, Shaoqiu Chen,, Yan Ni
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Missing value imputation approach for mass spectrometry-based metabolomics data
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Scientific reports
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2018
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8(1):663
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Li Yitao, Li Mengci, Ni Yan, Jia Wei,
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MCEE: A Data Preprocessing Approach for Metabolic Confounding Effect Elimination
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Analytical and Bioanalytical Chemistry
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2018
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410(11):2689-2699
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Mengci Li, Shouli Wang, Guoxiang Xie, Xiaohui Ma,, Wei Jia
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polyPK: An R Package for Pharmacokinetic Analysis of Multi-component Drugs Using a Metabolomics Approach
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bioinformatics
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2018
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34(10): 1792–1794
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Runmin Wei, Jingye Wang, Eric Jia,, Yan Ni, Wei Jia
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GSimp: A Gibbs Sampler Based Left-censored Missing Value Imputation Approach for Metabolomics Studies
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PLOS computational biology
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2018
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14(1): e1005973
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Xiaojiao Zheng, Fengjie Huang, Aihua Zhao, Sha Lei, Yunjing Zhang, Guoxiang Xie,, Chun Qu, Cynthia Rajani, Bing Dong, Defa Li, Wei Jia
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Bile acid is a significant host factor shaping the gut microbiome of diet induced obese mice
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BMC Biology
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2017
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15:120
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Guoxiang Xie, Shouli Wang, Hua Zhang, Aihua Zhao, Jiajian Liu, Yueming Ma, Ke Lan, Yan Ni, Changxiao Liu, Ping Liu,, Wei Jia
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Poly-Pharmacokinetic Study of a Multicomponent Herbal Medicine in Healthy Chinese Volunteers
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Clinical Pharmacology and Therapeutics
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2017
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doi: 10.1002/cpt.784.
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Linjing Zhao, Xiaojing Ma, Aihua Zhao, Yuqian Bao, Jiajian Liu,, Guoxiang Xie, Jun Panee, Mingming Su, Herbert Yu, Congrong Wang, Cheng Hu, Weiping Jia, Wei Jia
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A panel of free fatty acid ratios to predict the development of metabolic abnormalities in healthy obese individuals
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Scientific Reports
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2016
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1
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Haoyong Yu, Yan Ni, Yuqian Bao, Pin Zhang, Aihua Zhao,, Guoxiang Xie, Yinfang Tu, Lei Zhang, Mingming Su,Li Wei, Wei Jia, and Weiping Jia
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Chenodeoxycholic Acid as a Potential Prognostic Marker for Roux-en-Y Gastric Bypass in Chinese Obese Patients
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J Clin Endocrinol Metab
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2016
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doi: 10.1210/jc.2015-2884
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Xiaojiao Zheng,, Aihua Zhao, Xiaoyan Wang, Guoxiang Xie, Fengjie Huang, Jiajian Liu, Qing Zhao, Shouli Wang, Chongchong Wang, Mingmei Zhou, Jun Panee, Zhigang He, Wei Jia
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The Brain Metabolome of Male Rats across the Lifespan
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Scientific Reports
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2016
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10.1038/srep24125
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Zhao, Linjing; Zhao,, Tianlu; Chen, Wenlian; Liu, Jiajian; Wei, Runmin; Su, Jing; Tang, Xuelan; Liu, Keyi; Zhang, Ran; Xie, Guoxiang; Panee, Jun ; Qiu, Mingfeng; Jia, Wei
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Global and Targeted Metabolomics Evidences of the Protective Effect of Chinese Patent Medicine Jinkui Shenqi Pill on Adrenal Insufficiency after Acute Glucocorticoid Withdrawal in Rats
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Journal of Proteome Research
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2016
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1
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, Yan Ni, Xiaojing Ma, Yuqian Bao, Jiajian Liu, Fengjie Huang, Cheng Hu, Guoxiang Xie, Aihua Zhao, Weiping Jia*, Wei Jia*,
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Branched-chain and aromatic amino acid profiles and diabetes risk in Chinese populations
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Scientific Reports
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2016
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20594
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Haoyong Yu, Yan Ni, Yuqian Bao, Pin Zhang, Aihua Zhao,, Guoxiang Xie, Yinfang Tu, Lei Zhang, Mingming Su,Li Wei, Wei Jia, Weiping Jia
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Chenodeoxycholic Acid as a Potential Prognostic Marker for Roux-en-Y Gastric Bypass in Chinese Obese Patients
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J Clin Endocrinol Metab
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2015
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100(11):4222-30
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Lei Cai,, Jinglei Yang, Kejun Zhou, Xiaomei Yan, Wenzhong Chen, Liya Sun, Linlin Li, Shengying Qin, Peng Wang, Ping Yang, Donghong Cui, Margit Burmeister, Lin He1, Wei Jia, Chunling Wan
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Serum trace element differences between Schizophrenia patients and controls in the Han Chinese population
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scientific reports
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2015
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5:15013
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Jiang-Han Wang, Wen-Lian Chen, Jun-Min Li, Song-Fang Wu,, Yong-Mei Zhu, Wei-Na Zhang,Yang Li, Yun-Ping Qiu, Ai-Hua Zhao, Jian-Qing Mi, Jie Jin, Yun-Gui Wang, Qiu-Ling Ma, He Huang, De-Pei Wu,Qin-Rong Wang, Yan Li, Xiao-Jing Yan, Jin-Song Yan, Jian-Yong Li, Shuai Wang, Xiao-Jun Huang,Bing-Shun Wang, Wei Jia*, Yang Shen*, Zhu Chen, and Sai-Juan Chen
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Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China
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PNAS
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2013
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110(42): 17017-17022
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Zhang Y, Wu Y,, Yao L, Liu J, Pan X, Hu Y, Zhao A, Xie G, Jia W
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Assessing the Metabolic Effects of Aromatherapy in Human Volunteers
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Evidence-Based Complementary and Alternative Medicine
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2013
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2013(356381)
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, Y. Cao, Y. Zhang, J. Liu, Y. Bao, C. Wang, W. Jia, and A. Zhao
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Random Forest in Clinical Metabolomics for Phenotypic Discrimination and Biomarker Selection
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Evidence-Based Complementary and Alternative Medicine
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2013
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2981(83):-
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J.L. Yang,, L.Y. Sun, Z.M. Zhao, X. Qi, K.J. Zhou, Y. Cao, X.Y. Wang, Y.P. Qiu, M.M. Su, A.H. Zhao, P. Wang, P. Yang, J.L. Wu, G.Y. Feng, L. He, W. Jia*, and C.L. Wan
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Potential metabolite markers of schizophrenia
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Molecular Psychiatry
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2013
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2013(18):67-78
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Miao Jiang,, Hui Feng, Yinan Zhang, Li Li, Aihua Zhao, Xuyan Niu, Fei Liang, Minzhi Wang, Junping Zhan, Cheng Lu, Xiaojuan He, Lianbo Xiao, Wei Jia, Aiping Lu
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Serum Metabolic Signatures of Four Types of Human Arthritis
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Journal of Proteome Research
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2013
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8(12):769-779
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Tan B, Qiu Y, Zou X,, Xie G, Cheng Y, Dong T, Zhao L, Feng B, Hu X, Xu LX, Zhao A, Zhang M, Cai G, Cai S, Zhou Z, Zheng M, Zhang Y, Jia W.
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Metabonomics identifies serum metabolite markers of colorectal cancer
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Journal of Proteome Research
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2013
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12(6):3000-9
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L.X. Duan,, M. Chen, Y.Q. Zhou, G.H. Cui, A.H. Zhao, W. Jia, L.Q.Huang, X.Q. Qi
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Use of metabolomics approach to characterize Chinese medicinal material Huangqi
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Molecular Plant
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2012
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5(2):376-386
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, G.X. Xie, X. Y. Wang, J. Fan, Y.P. Qiu, X.J. Zheng, X. Qi, Y. Cao, M.M. Su, X.Y. Wang, L. X. Xu, Yun Y. P. Liu, W. Jia
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Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma
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Molecular & Cellular Proteomics
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2011
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10(11):1-13
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