- 基本信息
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导师姓名：
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谢冰
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学科代码：
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100212
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性别：
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男
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学科名称：
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眼科学
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培养单位：
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附属瑞金医院
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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眼科学 专业学位
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联系方式：
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专业领域代码：
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105116
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邮编：
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邮箱地址：
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brinkleybing@126.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中华医学会上海眼科分会青年委员
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上海交通大学医学院附属瑞金医院科技发展处副处长
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美国Johns Hopkins 大学/医院Wilmer眼科访问学者，博士后（2006-2008）
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瑞金-卢湾医疗联合体副秘书长，办公室主任
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上海交通大学医学院青联委员
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- 科研项目
| 81570853 | IL-17A调控巨噬细胞极化对视网膜新生血管形成的作用机 | 国家自然基金面上项目 |
2016-01~2019-12
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57万元
| 课题负责人 |
| 81100682 | T细胞激活与巨噬细胞极化对视网膜新生血管作用的研究 | 国家自然基金青年项目 |
2012-01~2015-12
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22万元
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| | 眼部肿瘤患病人群的流行病学调查 | 上海市科委慈善癌症研究中心项目 |
2011-10~2013-10
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4万元
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| 10QA1404600 | 巨噬细胞清除和极性改变抑制眼新生血管的机理研究 | 上海市科委启明星人才项目 |
2010-04~2012-03
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13万元
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| 09YZ86 | ID1基因敲除抑制视网膜新生血管的机制研究 | 上海市教委 |
2009-01~2011-12
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8万元
| 课题负责人 |
- 学术论文
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Sha Gao, Changwei Li, Yanji Zhu, Yanuo Wang, Ailing Sui, Yisheng Zhong,, Xi Shen
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PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy
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Scientific Reports
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2017
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Feb 17;7:42846
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Yanji Zhu, Ling Zhang, Qing Lu, Yushuo Gao, Yujuan Cai,
Ailing Sui, Ting Su, Xi Shen,
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Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy
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INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
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2017
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40: 281-292, 2017
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Yanji Zhu, Wei Tan, Anna M. Demetriades, Yujuan Cai, Yushuo Gao, Ailing Sui, Qing Lu, Xi Shen, Chunhui Jiang,,Xinghuai Sun.
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Interleukin-17A neutralization alleviated ocular neovascularization by promoting M2 and mitigating M1 macrophage polarization.
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Immunology
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2016
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147(4):414-28
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Jian Yu, Ruiping Gu, Yuan Zong, Huan Xu, Xiaolei Wang, Xinghuai Sun, Chunhui Jiang,, Yali Jia, and David Huang.
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Relationship Between Retinal Perfusion and Retinal Thickness in Healthy Subjects: An Optical Coherence Tomography Angiography Study.
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Invest Ophthalmol Vis Sci.
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2016
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57: 204-210
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2. Yujuan Cai, Wei Tan, Xi Shen, Yanji Zhu, Yushuo Gao, Ailing Sui, Qing Lu, Yisheng Zhong,
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Neutralization of IL-23 depresses experimental ocular Neovascularization.
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Experimental Eye Research
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2016
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2016(3): 242-251
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1. Yanji Zhu, Qing Lu, Ling Zhang, Yu Cheng, Qin Jiao, Yushuo Gao, Xi Shen,
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Investigation and evaluation of an innovative retinal neovascularization staining- one click staining.
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Int J Clin Exp Med.
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2016
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9 (2)
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Zhongjing Lin, Shouyue Huang,, and Yisheng Zhong.
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Peripapillary Choroidal Thickness and Open-Angle Glaucoma: A Meta-Analysis.
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Journal of Ophthalmology
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2016
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16 (5)
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Wang Y, Lu Q, Gao S, Zhu Y, Gao Y,, Shen X.
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Pigment Epithelium-derived Factor Regulates Glutamine Synthetase and l-Glutamate/l-Aspartate Transporter in Retinas with Oxygen-induced Retinopathy.
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Curr Eye Res.
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2014
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40(12):1232-44
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Zhu Y, Lu Q, Shen J, Zhang L, Gao Y, Shen X,
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Improvement and optimization of standards for a preclinical animal test model of laser induced choroidal neovascularization.
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PLoS One.
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2014
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4:94743-94743
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Wang J, Liu XH, Yang ZJ,, Zhong YS
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The effect of ROCK-1 activity change on the adhesive and invasive ability of Y79 retinoblastoma cells.
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BMC Cancer
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2014
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Feb 14:14-89
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Lu Qing, Ling Zhang, Xi Shen,Yanji Zhu, Qing wei Zhou, Renbao Gan, Hui Zhang, Jiaqi Gu, Yisheng Zhong,
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A novel and effective human hepatocyte growth factor kringle 1 domain inhibits ocular neovascularization.
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Exe Eye Res.
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2012
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105: 15-20
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Ping Huang, Jing Wang, Xi Shen, Qin Jiao, Yu Cheng,,Yisheng Zhong.
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The effects of erythropoietin on RhoA/Rho-associated kinase expression in rat retinal explants cultured with glutamate.
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MOL MED REP.
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2012
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6: 662-666
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, Jiao Q, Cheng Y, Zhong Y, Shen X
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Effect of pigment epithelium derived factor on the glutamate uptake in retinal Muller cells under high glucose conditions.
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Invest Ophthalmol Vis Sci.
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2012
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Feb 27; 53(2):1023-32
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Ling Zhang, Xi Shen, Qing Lu, Qingwei Zhou, Jiaqi Gu, Renbao Gan, Hui Zhang, Xiaodong Sun,
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A potential therapeutic strategy for inhibition of ocular neovascularization with a new endogenous protein: rhEDI-8t.
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Graefes Arch Clin Exp Ophthalmol.
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2012
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May;250(5):731-9
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Xi Shen, Yisheng Zhong,, Yu Cheng, Qin Jiao
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Pigment epithelium derived factor as an anti-inflammatory factor against decrease of glutamine synthetase expression in retinal Müller cells under high glucose conditions.
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Graefes Arch Clin Exp Ophthalmol127–1136
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2010
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248:1127–1136
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Aling Dong,, Jikui Shen, Yoshida T, Yokoi K, Hackett SF, Campochiaro PA.
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Oxidative Stress Promotes Ocular Neovascularization.
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J. Cell. Physiol.
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2009
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219 (3): 544-552
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, Jikui Shen, Aling Dong, Aymen Rashid, Glenn Stoller, Peter Campochiaro.
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Blockade of Sphingosine-1-Phosphate Reduces Macrophage Influx and Retinal and Choroidal Neovascularization.
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J. Cell. Physiol.
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2009
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218 (1): 192-198.
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, Shen J, Dong A, Swaim M, Hackett SF, Wyder L, Worpenberg S, Barbieri S, Campochiaro PA.
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An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization.
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FASEB J.
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2008
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22(8): 2775-83.
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Shen J, Yang X,, Chen Y, Swaim M, Hackett SF, Campochiaro PA
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MicroRNAs regulate ocular neovascularization.
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Mol Ther.
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2008
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16(7):1208-16
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Shen J,, Dong A, Swaim M, Hackett SF, Campochiaro PA.
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In vivo immunostaining demonstrates macrophages associate with growing and regressing vessels.
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Invest Ophthalmol Vis Sci.
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2007
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48(9): 4335-41
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Shen J,, Hatara CM, Hackett SF, Campochiaro PA.
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Vegf or EphA2 antisense polyamide-nucleic acids; vascular localization and suppression of retinal neovascularization.
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Mol Ther.
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2007
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15 (11): 1924-1930
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,叶纹,沈玺,钟一声
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转化生长因子-β1对人Tenon囊成纤维细胞表型转化的作用
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眼科新进展
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2006
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Vol.26: No.5
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, 叶纹, 钟一声, 沈玺
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转化生长因子-β1对人Tenon囊成纤维细胞表型转化的作用
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上海交通大学学报（医学版）.
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2006
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3: 263-265
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, 叶纹, 钟一声, 沈玺
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bFGF不能调节人结膜下Tenon's囊成纤维细胞表型改变
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细胞生物学
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2005
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2005; 8: 549-553
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