• 基本信息
    导师姓名： 侯照远 学科代码： 100100
    性别： 男 学科名称： 基础医学
    培养单位： 基础医学院 三级学科
    导师类型： 博士生导师 专业领域名称：
    联系方式： 上海市重庆南路280号西7号楼110室 Email：houzy@sjtu.edu.cn 专业领域代码：
    邮编： 200025 邮箱地址： houzy@sjtu.edu.cn
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    无
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    81872131去泛素化酶USP29促进乳腺癌细胞转移的分子机制自然基金委面上项目 2019-01~2022-12 60万元  课题负责人
    31671415LIM蛋白AJUBA在脂肪细胞分化中的作用国家自然科学基金 2017-01~2020-12 62万元  课题负责人
    81372309硫酰化修饰在Snail诱导的EMT和肿瘤转移中的作用国家自然科学基金面上项目 2014-01~2017-12 75万元  课题负责人
    81172028精氨酸甲基化修饰在Snail 诱导的EMT 和肿瘤转移中的作用国家自然科学基金面上项目 2012-01~2015-12 60万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Zhang B, Song L, Cai J, Li L, Xu H, Li M, Wang J, Shi M, Chen H, Jia H,  The LIM protein Ajuba/SP1 complex forms a feed forward loop to induce SP1 target genes and promote pancreatic cancer cell proliferation.  J Exp Clin Cancer Res.  2019  38(1):205 
    Hao Jia, Haixia Peng,  Ajuba: An emerging signal transducer in oncogenesis (review)  Pharmacol Res.  2019  151:104546 
    Zhang Y, Zou X, Qian W, Weng X, Zhang L, Zhang L, Wang S, Cao X, Ma L, Wei G, Wu Y,  Enhanced PAPSS2/VCAN sulfation axis is essential for Snail-mediated breast cancer cell migration and metastasis  Cell Death & Differ  2019  26(3):565-579 
    Wang Y, Weng X, Wang L, Hao M, Li Y, Hou L, Liang Y, Wu T, Yao M, Lin G, Jiang Y, Fu G,, Meng X, Lu J, Wang J.   HIC1 deletion promotes breast cancer progression by activating tumor cell/fibroblast crosstalk  JCI  2018  128(12):5235-5250 
    Xu B, Li Q, Chen N, Zhu C, Meng Q, Ayyanathan K, Qian W, Jia H, Wang J, Ni P,  The LIM protein Ajuba recruits DBC1 and CBP/p300 to acetylate ERα and enhances ERα target gene expression in breast cancer cells  Nucleic Acids Res.   2018  doi: 10.1093/nar/gky1306 
    Wang XJ, Qiao Y, Xiao MM, Wang L, Chen J, Lv W, Xu L, Li Y, Wang Y, Tan MD, Huang C, Li J, Zhao TC,, Jing N#, Chin YE#  Opposing Roles of Acetylation and Phosphorylation in LIFR-Dependent Self-Renewal Growth Signaling in Mouse Embryonic Stem Cells.   Cell Reports  2017  18(4):933-946 
    Chao Liu, Jiamin Wang, Xiaoyuan Yuan, Wenli Qian, Bosen Zhang, Minmin Shi, Junjie Xie, Baiyong Shen, Hong Xu,, Hao Chen#   Long Noncoding RNA uc.345 promotes tumorigenesis of pancreatic cancer by upregulation of hnRNPL expression  Oncotarget  2016  7(44):71556-71566 
    Jia Hao, Liwei Song, Qian Cong, Jiamin Wang, Yihong Zhang, Xiuqun Zou, Chenxi Zhang, Y. Eugene Chin, Xuehong Zhang, Zhiguang Li, Kai Zhu, Zhihai Peng, Bing Wang#, Haixia Peng#,  LIM protein AJUBA promotes colorectal cancer development through suppression of JAK1/STAT1/IFIT2 network  Oncogene  2016  . doi: 10.1038/onc.2016.418. [Epub ahead of print]) 
    Hongyan Fan, Weibing Dong, Qi Li, Xiuqun Zou, Yihong Zhang, Jiamin Wang, Shengxian Li, Wei Liu, Ying Dong, Haipeng Sun,  Ajuba preferentially binds LXRα/RXRγ heterodimer to enhance LXR target gene expression in liver cells.  Molecular Endocrinology  2015  29(11):1608-18. doi: 10.1210/me.2015-1046. Epub 2015 Sep 21 
    Qi Li, Haixia Peng, Hongyan Fan, Xiuqun Zou, Qian Liu, Yihong Zhang, Hong Xu, Yimin Chu, Chuangui Wang, Kasirajan Ayyanathan, Frank J. Rauscher III, Kaili Zhang,  The LIM protein Ajuba promotes adipogenesis by enhancing PPARγ and p300/CBP interaction  Cell Death & Differentiation   2015  2016 Jan;23(1):158-68. doi: 10.1038/cdd.2015.83. Epub 2015 Jun 26. 
    Du S, Guan Z, Hao L, Song Y, Wang L, Gong L, Liu L, Qi X,, Shao S.  Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration  PLoS One  2014  9(1):e85804 
    Chen J, Xu H, Zou X, Wang J, Zhu Y, Chen H, Shen B, Deng X, Zhou A, Chin YE, Rauscher FJ 3rd, Peng C,  Snail Recruits Ring1B to Mediate Transcriptional Repression and Cell Migration in Pancreatic Cancer Cells  Cancer Research  2014  74(16):4353-63 
    Ni P, Xu H, Chen C, Wang J, Liu X, Hu Y, Fan Q,, Lu Y  Serum starvation induces DRAM expression in liver cancer cells via histone modifications within its promoter locus  PLoS One  2012  7(12):e50502