- 基本信息
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导师姓名：
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孙勇伟
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学科代码：
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100210
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性别：
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男
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学科名称：
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外科学
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培养单位：
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附属仁济医院
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三级学科
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普外
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导师类型：
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硕士生导师
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专业领域名称：
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外科学 专业学位
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联系方式：
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syw0616@126.com
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专业领域代码：
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105111
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邮编：
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200127
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邮箱地址：
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syw0616@hotmail.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中国医师协会外科医师分会肿瘤外科委员会委员
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中国医师协会胰腺神经内分泌肿瘤专业委员会委员
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中国医疗保健国际交流促进会胰腺神经内分泌肿瘤专业委员会委员
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中国抗癌协会胰腺癌专业委员会委员
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上海市普外科胰腺外科学组委员
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中国临床肿瘤学会（CSCO）胰腺癌专家委员会委员
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上海市医学会普外科专科分会胰腺外科学组副组长
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中华医学会肿瘤学分会胰腺肿瘤学组委员
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- 科研项目
| 81874175 | SLIT2/ROBO1调控胰腺导管腺癌肝转移前微环境的形成及发展的机制研究 | 国家自然科学基金委员会 |
2019-01~2022-12
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57万元
| 课题负责人 |
| PYI-17-004 | MDT联合ERAS管理运用于胰十二指肠切除术的临床研究 | 仁济医院临床科研创新培育基金 |
2018-01~2020-12
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15万元
| 课题负责人 |
| 17411952100 | 基于lncRNA的胰腺癌血清学诊断标志物研究 | 上海市科学技术委员会 |
2017-10~2020-09
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45万元
| 课题负责人 |
| 81602414 | P53突变介导的AHNAK2蛋白高表达促进胰腺癌瓦伯格效应的机制研究 | 国家自然科学基金委员会 |
2017-01~2019-12
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19万元
| 课题参与人 |
| RJYSJJ-201503 | 胰腺癌肝转移全外显子组测序研究 | 上海市肿瘤研究所“癌基因及相关基因国家重点实验室” |
2015-09~2016-09
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40万元
| 课题负责人 |
| 2014AA020609 | 胰腺癌的蛋白质分子网络研究 | 中华人民共和国科学技术部（863计划）
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2014-01~2016-12
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814万元
| 课题参与人 |
| Y-N2013-014 | 长效奥曲肽联合化疗在胃肠胰神经内分泌癌治疗中的作用探寻 | 中国抗癌协会临床肿瘤学协作专业委员会 |
2013-06~2016-06
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3万元
| 课题负责人 |
| 院士基金 | 胰腺癌高表达关键分子群的验证 | 上海市肿瘤研究所“癌基因及相关基因国家重点实验室" |
2013-04~2014-04
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50万元
| 课题负责人 |
| 院士基金 | 全基因组测序研究乙肝病毒DNA在胰腺癌中的整合及意义 | 上海市肿瘤研究所“癌基因及相关基因国家重点实验室” |
2013-03~2014-02
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50万元
| 课题负责人 |
| 10411965200 | 内皮源性血管舒张物质在门静脉高压症微动脉RhoA/Rho激酶信号通路的作用 | 上海市科学技术委员会 |
2010-01~2013-03
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10万元
| 课题负责人 |
| 09DZ1908502 | 国产及进口吻合器的临床验证 | 上海市科学技术委员会 |
2009-10~2012-09
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15万元
| 课题负责人 |
| PKJ2007-y02 | 肝肺综合征流行病学和发病机制的临床研究 | 上海市浦东新区科委 |
2008-09~2010-08
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15万元
| 课题负责人 |
| 054041 | 门肺高压症诊断方法和发病机制的临床研究 | 上海市卫生局 |
2005-08~2007-12
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5万元
| 课题负责人 |
- 学术论文
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Ningning Niu#, Ping Lu#, Yanlin Yang, Ruizhe He, Li Zhang, Juanjuan Shi, Jinghua Wu, Minwei Yang, Zhi-Gang Zhang, Li-Wei Wang, Wei-Qiang Gao, Aida Habtezion, Gary Guishan Xiao,, Li Li*, Jing Xue*
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Loss of Setd2 promotes Kras-induced acinar-to-ductal metaplasia and epithelia-mesenchymal transition during pancreatic carcinogenesis
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Gut
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2020
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69(4): 715-726
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Jianyu Yang#, Junfeng Zhang#, Wei Lui#, Yanmiao Huo, Xueliang Fu, Minwei Yang, Rong Hua*, Liwei Wang*,
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Patients with hepatic oligometastatic pancreatic body/tail ductal adenocarcinoma may benefitfrom synchronous resection
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HPB : the official journal of the International Hepato Pancreato Biliary Association
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2020
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22(1):91-101
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Min-Wei Yang#, Ling-Ye Tao#, Yong-Sheng Jiang#, Jian-Yu Yang#, Yan-Miao Huo, De-Jun Liu, Jiao Li, Xue-Liang Fu, Ruizhe He, Chaoyi Lin, Wei Liu, Jun-Feng Zhang, Rong Hua, Qing Li, Shu-Heng Jiang, Li-Peng Hu, Guang-Ang Tian, Xiao-Xin Zhang, Ningning Niu, Ping Lu, Juanjuan Shi, Gary G. Xiao, Li-Wei Wang, Jing Xue*, Zhi-Gang Zhang*,
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Perineural invasion reprograms the immune microenvironment through cholinergic signaling in pancreatic ductal adenocarcinoma
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Cancer Research
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2020
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80(10):1991-2003
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Shu-Heng Jiang#, Li-Li Zhu#, Man Zhang#, Rong-Kun Li#, Qin Yang#, Jiang-Yu Yan, Ce Zhang, Jian-Yu Yang, Fang-Yuan Dong, Miao Dai, Li-Peng Hu, Jun Li, Qing Li, Ya-Hui Wang, Xiao-Mei Yang, Yan-Li Zhang, Hui-Zhen Nie, Lei Zhu, Xue-Li Zhang, Guang-Ang Tian, Xiao-Xin Zhang, Xiao-Yan Cao, Ling-Ye Tao, Shan Huang, Yong-Sheng Jiang, Rong Hua, Kathy Qian Luo, Jian-Ren Gu,, Shangwei Hou*, Zhi-Gang Zhang*
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GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca2 signalling in a GABA-independent manner
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Gut
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2019
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68(11): 1994-2006
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Min-Wei Yang#, Xue-Liang Fu, Yong-Sheng Jiang, Xiao-Jing Chen, Ling-Ye Tao, Jian-Yu Yang, Yan-Miao Huo, Wei Liu, Jun-Feng Zhang, Pei-Feng Liu, Qiang Liu, Rong Hua, Zhi-Gang Zhang,, De-Jun Liu*
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Clinical significance of programmed death 1/programmed death ligand 1 pathway in gastric neuroendocrine carcinomas
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World journal of gastroenterology : WJG
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2019
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25(14):1684-1696
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De-Jun Liu#, Rong Hua,
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Current treatment status in pancreatic neuroendocrine neoplasms
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Chinese clinical oncology
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2019
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8(2):20
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Juanjuan Shi#, Ping Lu, Wenyan Shen, Ruizhe He, Min-Wei Yang, Yuan Fang,, Ningning Niu*, Jing Xue*
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CD90 highly expressed population harbors a stemness signature and creates an immunosuppressive niche in pancreatic cancer
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Cancer letters
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2019
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453:158-169
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Min-Wei Yang#, Ling-Ye Tao, Jian-Yu Yang, Yong-Sheng Jiang, Xue-Liang Fu, Wei Liu, Yan-Miao Huo, Jiao Li, Jun-Feng Zhang, Rong Hua, Xiao-Ran Qin,, De-Jun Liu*.
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SFRP4 is a prognostic marker and correlated with Treg cell infiltration in Pancreatic Ductal Adenocarcinoma
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American journal of Cancer Research
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2019
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9(2):363-377
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Yongsheng Jiang#, Ruizhe He#, Yuhong Jiang#, Dejun Liu#, Lingye Tao, Minwei Yang, Chaoyi Lin, Yang Shen, Xueliang Fu, Jianyu Yang, Jiao Li, Yanmiao Huo, Rong Hua, Wei Liu, Junfeng Zhang, Baiyong Shen*, Zhigang Zhang*,
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Transcription Factor NFAT5 Contributes to the Glycolytic Phenotype Rewiring and Pancreatic Cancer Progression via Transcription of PGK1
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Cell Death & Disease
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2019
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10(12): 1-13
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Li-Peng Hu#, Xiao-Xin Zhang#, Shu-Heng Jiang#, Ling-Ye Tao, Qing Li, Li-Li Zhu, Ming-Wei Yang, Yan-Miao Huo, Yong-Sheng Jiang, Guang-Ang Tian, Xiao-Yan Cao, Yan-Li Zhang, Qin Yang, Xiao-Mei Yang, Ya-Hui Wang, Jun Li, Gary Guishan Xiao*,, Zhi-Gang Zhang*
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Targeting Purinergic Receptor P2Y2 Prevents the Growth of Pancreatic Ductal Adenocarcinoma by Inhibiting Cancer Cell Glycolysis
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Clinical Cancer Research
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2019
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25(4): 1318-1330
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Jianyu Yang#, Yongsheng Jiang#, Ruizhe He#, Wei Liu#, Minwei Yang, Lingye Tao, Jiao Li, Dejun Liu, Yanmiao Huo, Xueliang Fu, Junfeng Zhang, Yang Shen, Rong Hua*, Zhi-Gang Zhang*,
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DKK2 impairs tumor immunity infiltration and correlate with poor prognosis in pancreatic ductal adenocarcinoma
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Journal of Immunology Research
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2019
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(3):1-12
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Xiao-Yan Cao#, Xiao-Xin Zhang#, Min-Wei Yang#, Li-Peng Hu, Shu-Heng Jiang, Guang-Ang Tian, Li-Li Zhu, Qing Li*,, Zhi-Gang Zhang*
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Aberrant upregulation of KLK10 promotes metastasis via enhancement of EMT and FAK/SRC/ERK axis in PDAC
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Biochemical and biophysical research communications
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2018
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499(3):584-593
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Weizhi He#, Jinghua Wu, Juanjuan Shi, Yan-Miao Huo, Wentao Dai, Jing Geng, Ping Lu, Min-Wei Yang, Yuan Fang, Wei Wang, Zhi-Gang Zhang, Aida Habtezion*,, Jing Xue*
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IL-22RA1/ STAT3 signaling promotes stemness and tumorigenicity in pancreatic cancer.
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Cancer research
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2018
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78(12):3293-3305
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De-Jun Liu#, Xue-Liang Fu, Wei Liu, Lu-Ying Zheng, Jun-Feng Zhang, Yan-Miao Huo, Jiao Li, Rong Hua, Qiang Liu,
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Clinicopathological, treatment, and prognosis study of 43 gastric neuroendocrine carcinomas
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World journal of gastroenterology : WJG
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2017
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23(3):516-24
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De-Jun Liu#,Yue-Xia Xie#, Xiao-Xing Liu#, Yan-Miao Huo, Min-Wei Yang, Xue-Liang Fu, Wei Liu, Jian Yu Yang, Jiao Li, Rong Hua, Pei-Feng Liu,, Jun-Feng Zhang*
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The role of Dickkopf-1 as a potential prognostic marker in pancreatic ductal adenocarcinoma
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Cell cycle
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2017
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16(17):1622-9
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Shuheng Jiang#, Lili Zhu#, Jianyu Yang#, Lipeng Hu, Jianren Gu, Xin Xing*,, Zhigang Zhang*
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Integrated expression profiling of potassium channels identifys KCNN4 as a prognostic biomarker of pancreatic cancer
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Biochemical and biophysical research communications
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2017
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494(1-2):113-119
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Shu-Heng Jiang#, Jun Li#, Fang-Yuan Dong#, Jian-Yu Yang, De-Jun Liu, Xiao-MeiYang, Ya-Hui Wang, Min-Wei Yang, Xue-Liang Fu, Xiao-Xin Zhang, Qing Li, XiuFeng Pang, Yan-Miao Huo, Jiao Li, Jun-Feng Zhang, Ho-Young Lee, Su-Jae Lee,Wen-Xin Qin, Jian-Ren Gu,, Zhi-Gang Zhang*.
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Increased Serotonin Signaling Contributes to the Warburg Effect in Pancreatic Tumor Cells Under Metabolic Stress and Promotes Growth of Pancreatic Tumors in Mice
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Gastroenterology
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2017
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153(1):277-91.e19
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Wei Liu#, Xue-Liang Fu#, Jian-Yu Yang#, Min-Wei Yang, Ling-Ye Tao, De-Jun Liu, Yan-Miao Huo, Jun-Feng Zhang, Rong Hua*,
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Elevated expression of CTHRC1 predicts unfavorable prognosis in patients with pancreatic ductal adenocarcinoma
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American journal of cancer research
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2016
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6(8):1820-7
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Xue-Liang Fu#, De-Jun Liu#, Ting-Ting Yan#, Jian-Yu Yang, Min-Wei Yang, Jiao Li, Yan-Miao Huo, Wei Liu, Jun-Feng Zhang, Jie Hong, Rong Hua*, Hao-Yan Chen*,
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Analysis of long non-coding RNA expression profiles in pancreatic ductal adenocarcinoma
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Scientific reports
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2016
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6:33535
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Wei Liu#, Xue-Liang Fu#, Jian-Yu Yang#, De-Jun Liu, Jiao Li, Jun-Feng Zhang, Yan-Miao Huo, Min-Wei Yang, Rong Hua*,
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Efficacy of Neo-Adjuvant Chemoradiotherapy for Resectable Pancreatic Adenocarcinoma: A PRISMA-Compliant Meta-Analysis and Systematic Review
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Medicine
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2016
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95(15):e3009
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Shu-Heng Jiang#, Yang Wang#, Jian-Yu Yang#, Jiao Li#, Ming-Xuan Feng, Ya-Hui Wang, Xiao-Mei Yang, Ping He, Guang-Ang Tian, Xiao-Xin Zhang, Qing Li, Xiao-Yan Cao, Yan-Miao Huo, Min-Wei Yang, Xue-Liang Fu, Jiao Li, De-Jun Liu, Miao Dai, Shan-Yun Wen, Jian-Ren Gu, Jie Hong*, Rong Hua*, Zhi-Gang Zhang*,
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Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer
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Oncotarget
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2015
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7(4): 4227-4240
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Jian-Yu Yang#, Shu-Heng Jiang#, De-Jun Liu#, Xiao-Mei Yang, Yan-Miao Huo, Jiao Li, Rong Hua, Zhi-Gang Zhang*,
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Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma
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Scientific reports
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2015
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5:10575
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Yanmmiao Huo#, Jiachang Chi#, Junfeng Zhang, Wei Liu, Dejun Liu, Jiao Li, Jianyu Yang, Rong Hua*,
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Endovascular intervention for delayed post-pancreaticoduodenectomy hemorrhage: clinical features and outcomes of transcatheter arterial embolization and covered stent placement
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International journal of clinical and experimental medicine
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2015
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8(5): 7457-7466
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Jian-Yu Yang#, Min-Wei Yang#, Yan-Miao Huo#, Wei Liu#, De-Jun Liu, Jiao Li, Jun-Feng Zhang, Rong Hua*,
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High expression of WISP-1 correlates with poor prognosis in pancreatic ductal adenocarcinoma
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American journal of translational research
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2015
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7(9): 1621-1628
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Yanmiao Huo#, Minwei Yang#, Wei Liu#, Jianyu Yang#, Xueliang Fu, Dejun Liu, Jiao Li, Junfeng Zhang, Rong Hua*,
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High expression of DDR1 is associated with the poor prognosis in Chinese patients with pancreatic ductal adenocarcinoma
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Journal of experimental & clinical cancer research
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2015
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7(9): 1621-1628
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Ting-Ting Yan#, Xue-Liang Fu#, Jiao Li#, Ying-Nan Bian#, De-Jun Liu, Rong Hua, Lin-Lin Ren, Cheng-Tao Li,, Hao-Yan Chen*, Jing-Yuan Fang*, Jie Hong*.
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Downregulation of RPL15 may predict poor survival and associate with tumor progression in pancreatic ductal adenocarcinoma
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Oncotarget
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2015
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6(35):37028-42
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Hua R, Zhang JF, Liu W, Huo YM,
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Signet-ring cell carcinoma coexisting with adenocarcinoma arising in a choledochal cyst: report of a case
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Surg Today
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2015
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2015,45(8): 1049-1052
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Jiao Li#, Dejun Liu, Rong Hua, Junfeng Zhang, Wei Liu, Yanmiao Huo, Yifan Cheng, Jie Hong*,
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Long non-coding RNAs expressed in pancreatic ductal adenocarcinoma and lncRNA BC008363 an independent prognostic factor in PDAC
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Pancreatology
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2014
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14(5): 385-390
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Wei Chen#, De-Jun Liu#, Yan-Miao Huo, Zhi-Yong Wu,
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Reactive oxygen species are involved in regulating hypocontractility of mesenteric artery to norepinephrine in cirrhotic rats with portal hypertension
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International journal of biological sciences
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2014
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10(4): 386-395
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, Y-F Chen#, J Li#, Y-M Huo#, D-J Liu, R Hua, J-F Zhang, W Liu, J-Y Yang, X-L Fu, T Yan, J Hong*, H Cao*.
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A novel long non-coding RNA ENST00000480739 suppresses tumour cell invasion by regulating OS-9 and HIF-1α in pancreatic ductal adenocarcinoma
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British journal of cancer
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2014
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111(11): 2131-2141
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Jian-Yu Yang#,, De-Jun Liu, Jun-Feng Zhang, Jiao Li, Rong Hua*.
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MicroRNAs in stool samples as potential screening biomarkers for pancreatic ductal adenocarcinoma cancer
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American journal of cancer research
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2014
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4(6): 663-673
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De-Jun Liu#, Wei Chen, Yan-Miao Huo, Wei Liu, Jun-Feng Zhang, Rong Hua,
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Prostacyclin decreases splanchnic vascular contractility in cirrhotic rats
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Hepatobiliary & pancreatic diseases international : HBPD INT
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2014
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13(4): 416-422
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Jun-Feng Zhang#, Rong Hua, De-Jun Liu, Wei Liu, Yan-Miao Huo,
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Effect of CD74 on the prognosis of patients with resectable pancreatic cancer
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Hepatobiliary & pancreatic diseases international : HBPD INT
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2014
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13(1):81-86
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Sun Y, Qin LB, Liu DJ, Liu CH,, Duan YR*.
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Fast Detection of Alpha-Fetoprotein-L3 Using Lens Culinaris Agglutinin Immobilized Gold Nanoparticles
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J Nanosci Nanotechnol
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2014
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2014,14(6): 4078-4081
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W Liu#, R Hua, J-F Zhang, Y-M Huo, D-J Liu,
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First report of primary pancreatic natural killer/T-cell nasal type lymphoma
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European review for medical and pharmacological sciences
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2013
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17(3): 318-322
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花荣,吴卉,张希文,
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Probable catastrophic antiphospholipid syndrome complicated with primary sclerosing cholangitis.
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journal of digestive disease
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2012
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13(11):601-3
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,花荣,霍砚淼,曹晖,吴志勇,罗蒙,徐庆,陈炜,孔宪明
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The characteristics of respiratory function and pulmonary hemodynamics in patients with portal hypertension
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journal of digestive disease
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2012
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13(2):75-81
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霍砚淼,花荣,陈炜,
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Clinical study onpulmonary diffusion function in patients with chronic liver disease
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Journal of Digestive Diseases
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2010
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11(5):291–8
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,陈炜,罗蒙,花荣,刘巍,霍砚淼,吴志勇,曹晖
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Evaluation of surgical procedure selection based on intraoperative free portal pressure measurement in patients with portal hypertension
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Hepatobiliary & Pancreatic Diseases International
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2010
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9(3):269-74.
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