- 基本信息
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导师姓名：
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陈晓翔
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学科代码：
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100201
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性别：
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男
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学科名称：
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内科学
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培养单位：
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附属仁济医院
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三级学科
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风湿病
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导师类型：
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博士生导师
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专业领域名称：
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内科学 专业学位
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联系方式：
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专业领域代码：
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105101
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邮编：
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邮箱地址：
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xiaoxiang0721@126.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
- 科研项目
| 2022YFF0710202 | 于新型纳米结构的元素标记探针开发 | 科技部重点研发 |
2022-10~2025-10
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130万元
| 课题负责人 |
| 81971534 | Fra2/AP-1通过OX40+细胞调节银屑病的免疫学机制 | 国家自然基金面上项目 |
2020-01~2023-12
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55万元
| 课题负责人 |
| 81771729 | B细胞通过HIF1α/IL-10通路调控自身免疫和骨稳态的机制 | 国家自然基金 |
2018-01~2022-12
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55万元
| 课题负责人 |
| 14430712000 | HIF1a通过骨髓B细胞调节破骨细胞分化和关节炎的发生机制 | 上海市科委国际交流重点项目 |
2014-07~2017-06
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30万元
| 课题负责人 |
| 81273306 | 狼疮致病靶分子 OAS1 新功能的研究：通过pre-miR-105 对自身抗体唾液酸化调节机制 | 国家自然基金 |
2013-01~2016-12
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60万元
| 课题负责人 |
| 10ZR1418600 | miR-105对SLE患者IgG-Fc糖基化修饰及功能的影响 | 上海市科委 |
2010-04~2013-03
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10万元
| 课题负责人 |
- 学术论文
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Fan C, Li J, Li Y, Jin Y, Feng J, Guo R, Meng X, Gong D, Chen Q, Du F, Zhang C, Lu L, Deng J,
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Hypoxia-inducible factor-1α regulates the interleukin-6 production by B cells in rheumatoid arthritis
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Clin Transl Immunology
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2023
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12(5):e1447.
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Shen LC# , Yin HL# , Sun L #, Zhang ZL , Jin YY, Cao Shan, Fu Q, Fan CF, Bao CD, Lu LJ, Zhan YF, Xu XJ,, Yan QR*.
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Iguratimod attenuated fibrosis in systemic sclerosis via targeting early growth response 1 expression
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Arthritis Res Ther
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2023
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25(1):151.
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Li YX #, Guo RR #, Li WJ #, Feng JQ, Jin YY, Li J, Lu LJ,Feng XB,
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Serosal involvement in adult-onset Still’s disease: A multicentre and retrospective study
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Modern Rheumatology
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2022
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33(3):579-587
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Sheng N#, Wang WW#, Zhang B, Zhao JJ, Chen HJ, Feng PF, Gao YY*,
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Evaluation of Tag Single-Nucleotide Polymorphisms for Identifying HLA-B27 Status in a Chinese Han Population.
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J Rheumatol.
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2022
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jrheum.220958.
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Cao S, Meng XY, Li YX, Sun L, Jiang LD, Xuan HQ*,
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Bile Acids Elevated in Chronic Periaortitis Could Activate Farnesoid-X-Receptor to Suppress IL-6 Production by Macrophages
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Front Immunol
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2021
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12:632864.
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Guo R, Zhang T, Meng X, Lin Z, Lin J, Gong Y, Liu X, Yu Y, Zhao G, Ding X,, Lu L.
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Lymphocyte mass cytometry identifies a CD3-CD4+ cell subset with a potential role in psoriasis.
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JCI Insight.
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2019
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pii: 125306.
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Lichong SHEN, Qingran YAN,
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Efficacy of Combination Therapy With Pirfenidone and Low-Dose Cyclophosphamide for Refractory Interstitial Lung Disease Associated With Connective Tissue Disease: A Case-Series of Seven Patients
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Arch Rheumatol
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2019
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2020;35(x):i-ix
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Ruru Guo, Yang Tu, Shan Cao, Zhen Lin, Yang Song, Suli Wang,, Liangjing Lu*.
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Abnormal expression of receptor-interacting protein kinase-1 involves in neutrophil extracellular trap formation in patients with systemic lupus erythematosus.
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Cellular Physiology and Biochemistry
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2018
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45:2317-2328.
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Deng J, Fan C, Gao X, Zeng Q, Guo R, Wei Y, Chen Z, Chen Y, Gong D, Feng J, Xia Y, Xiang S, Gong S, Yuan L, Shen W, Shen W, Lin L, Jiang T, He D, Lu L,, Yu D.
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Signal Transducer and Activator of Transcription 3 Hyperactivation Associates With Follicular Helper T Cell Differentiation and Disease Activity in Rheumatoid Arthritis.
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Front Immunol.
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2018
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4;9:1226.
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Wang J, Chen GL, Cao S, Zhao MC, Liu YQ,, Qian C.
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Adipogenic niches for melanoma cell colonization and growth in bone marrow.
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Lab Invest
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2017
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97(6):737-745.
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Chen GL, Luo Y, Eriksson D, Meng X, Qian C, B?uerle T,, Schett G, Bozec A.
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High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6.
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Oncotarget.
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2016
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7(18):26653-69.
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, Li ZG, Wu HX, Zhao DB, Li XF, Xu JH, Tao Y, Yang NP, Hu SX, Huang AB, Jiang LD, Wang GC, Zhang X, Bao CD.
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A randomized, controlled trial of efficacy and safety of Anbainuo, a bio-similar etanercept, for moderate to severe rheumatoid arthritis inadequately responding to methotrexate.
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Clin Rheumatol
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2016
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35(9):2175-83.
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, Chen YQ, Ye S.
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Measuring decreased serum IgG sialylation: a novel clinical biomarker of lupus.
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lupus
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2015
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24(9):948-54.
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, Baum W, Dwyer D, Stock M, Schwabe K, Ke HZ, Stolina M, Schett G, Bozec A.
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Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis.
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Ann Rheum Dis.
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2013
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72(10):1732-6.
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, Dai Q, Huang AB,et al
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A multicenter, randomized, double-blind clinical trial of combination therapy with Anbainuo, a novel recombinant human TNFRII:Fc fusion protein, plus methotrexate versus methotrexate alone or Anbainuo alone in Chinese patients with moderate to severe rheumatoid arthritis.
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Clin Rheumatol
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2013
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32(1):99-108
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Lu XY,, Huang LD, et al
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Anti-alpha-internexin autoantibody from neuropsychiatric lupus induce cognitive damage via inhibiting axonal elongation and promote neuron apoptosis.
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PLoS One
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2010
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15;5(6):e11124.
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, Gu YY, Li SJ, Qian J, Hwang KK, Chen PP, Chen SL, Yang CD.
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Some plasmin-induced antibodies bind to cardiolipin, display lupus anticoagulant activity and induce fetal loss in mice.
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J Immunol.
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2007
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26(10):1647-54.
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