- 基本信息
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导师姓名：
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钟鸣
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学科代码：
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100210
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性别：
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男
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学科名称：
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外科学
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培养单位：
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附属仁济医院
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三级学科
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普外
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导师类型：
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博士生导师
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专业领域名称：
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外科学 专业学位
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联系方式：
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上海市浦东新区浦建路160号仁济医院东部7号楼12楼
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专业领域代码：
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105111
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邮编：
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200127
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邮箱地址：
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drzhongming@hotmail.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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仁济医院临床模拟教学团队首席教师
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中国医师协会结直肠肿瘤专业委员会委员
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中国抗癌协会腔镜与机器人外科分会常务委员
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中国抗癌协会大肠癌专业委员会委员
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中华结直肠外科学院学术委员会委员
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上海市炎症性肠病研究中心副主任
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中国研究型医院学会微创外科专业委员会委员
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中国医师协会外科分会结直肠专业委员会委员
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仁济临床医学院实训中心微创外科培训基地主任
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《腹腔镜外科杂志》编委
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中华医学会外科分会腹腔镜与内镜外科学组委员
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仁济医院结直肠肿瘤多学科团队首席专家
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上海交通大学结直肠癌诊治中心副主任
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中国医师协会外科分会微创外科专业委员会委员
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- 科研项目
| 81873555 | 炎症性肠病中CCL5缺失导致肠道菌群紊乱引发Th17/Treg失衡的机制研究 | 国家自然基金面上项目 |
2019-01~2022-12
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53万元
| 课题负责人 |
| 81672347 | 结直肠癌中SIRT1高表达的幼稚型粒细胞的形成机制及其作用研究 | 国家自然科学基金面上项目 |
2017-01~2020-12
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57万元
| 课题负责人 |
| PYMDT-011 | 基于多学科团队（MDT）的可切除结直肠癌肝转移优化治疗方案选择的临床研究 | 仁济医院临床科研创新培育基金计划 |
2016-06~2017-05
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15万元
| 课题负责人 |
| 201540031 | 结直肠癌患者外周血CD4+ T细胞中ICOS表达作为肝转移早期诊断的可行性研究 | 上海市卫生和计划委员会 |
2016-01~2018-12
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15万元
| 课题负责人 |
| ZHYY-ZXYJHZX-2-17 | 围手术期厚朴排气合剂的使用在结直肠癌快速康复中的作用研究 | 上海市卫生和计划生育委员会 |
2015-12~2017-12
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10万元
| 课题负责人 |
| W2015JZC11 | NICE分型对结直肠疾病诊治准确性的临床研究 | 国家卫生计生委 |
2015-06~2017-06
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10万元
| 子课题负责人 |
| 13DZ1942806 | 下消化道微创钛合金手术器械的研发及临床转化 | 上海市科学技术委员会 |
2013-09~2016-09
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20万元
| 课题负责人 |
| SHDC12012105 | 结肠癌早期诊断及预后评估分子诊断标记物组合构建的
临床应用研究
| 市级课题 |
2013-01~2015-12
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20万元
| 子课题负责人 |
| W2012FZ145 | 分子诊断技术在结直肠癌个体化治疗中的应用研究 | 卫生部 |
2012-04~2014-03
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10万元
| 主要责任人 |
| 320.6750.1218 | CKS2在大肠癌生物学行为中的角色及应用潜能 | 吴阶平医学基金 |
2012-03~2014-02
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10万元
| 主要责任人 |
| 2008132 | 结肠癌干细胞CD133超表达与治疗反应及生存期的相关性研究 | 上海市卫生局 |
2009-01~2010-12
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3万元
| 课题负责人 |
| 05HX21026 | 化疗对结直肠癌患者血浆金属蛋白酶及其抑制物水平影响的研究 | 横向课题 |
2006-01~2008-12
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5万元
| 课题负责人 |
- 学术论文
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Shao-Lan Qin, Yong Zhou, Jian-Jun Chen, Yang Luo, Yi-Er Qiu, Shui-Ping Tu ,
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Low levels of TSC22 enhance tumorigenesis by inducing cell proliferation in colorectal cancer
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Biochem Biophys Res Commun
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2018
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497(4):1062-1067
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Lin-Lin Ren, Ting-Ting Yan, Chao-Qin Shen, Jia-Yin Tang, Xuan Kong, Ying-Chao Wang, Jinxian Chen, Qiang Liu, Jie He,, Hao-Yan Chen, Jie Hong, Jing-Yuan Fang
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The distinct role of strand-specific miR-514b-3p and miR-514b-5p in colorectal cancer metastasis
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Cell Death Dis
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2018
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9(6):687
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Min-Hao Yu, Yang Luo, Zhi-Jie Cong, Yi-Fei Mu, Yi-Er Qiu,
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MicroRNA-590-5p Inhibits Intestinal Inflammation by Targeting YAP
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J Crohns Colitis
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2018
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12(8):993-1004
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Shengbo Zhang,, Chao Wang, Yanjie Xu, Wei-Qiang Gao, Yan Zhang
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CCL5-deficiency enhances intratumoral infiltration of CD8+ T cells in colorectal cancer
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Cell Death Dis
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2018
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9(7):766
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Ben Yue, Chenchen Liu, Huimin Sun, Mengru Liu, Chenlong Song, Ran Cui, Shenglong Qiu,
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A Positive Feed-Forward Loop between LncRNA-CYTOR and Wnt/β-Catenin Signaling Promotes Metastasis of Colon Cancer
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Mol Ther
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2018
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26(5):1287-1298
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Yi-Er Qiu, Jun Qin, Yang Luo, Shao-Lan Qin, Yi-Fei Mu, Ran Cun, Hou-li Jiang, Jian-Jun Chen, Min-Hao Yu,
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Increased epoxyeicosatrienoic acids may be part of a protective mechanism in human ulcerative colitis, with increased CYP2J2 and reduced soluble epoxide hydrolase expression
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Prostaglandins Other Lipid Mediat
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2018
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136:9-14
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骆洋,陈建军,秦骏,俞旻皓,秦绍岚,仇伊尔,
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腹腔镜直肠癌手术中保留左半结肠血管对第3站淋巴结清扫的影响
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中华消化外科杂志
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2018
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17(2):1-7
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Jian-Jun Chen, Yang Luo, Yong Zhou, Shao-Lan Qin, Ran Cui, Min-Hao Yu, Jun Qin,
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Promotion of Tumor Growth by ADAMTS4 in Colorectal Cancer: Focused on Macrophages
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Cell Physiol Biochem
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2018
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46(4):1693-1703
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陈建军,
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内"8"字缝合法在腹腔镜结直肠手术中的应用
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中华胃肠外科杂志
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2018
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21(3):281-284
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从志杰,秦骏,崔然,王颢,于恩达,
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直肠癌术后须再手术吻合口漏影响因素研究
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中国实用外科杂志
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2017
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12(37):1406-1412
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Dong-Xing Cao, Shao-Lan Qin, Yi-Fei Mu,
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The role of MRP1 in the multidrug resistance of colorectal cancer
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Oncol Lett
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2017
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13(4):2471-2476
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Yang Luo, Yi-Er Qiu, Yi-Fei Mu, Shao-Lan Qin, Yang Qi,, Min-Hao Yu, Li-Ying Ma
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Plastic wound protectors decreased surgicalsite infections following laparoscopic-assisted colectomy for colorectal cancer
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Medicine (Baltimore)
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2017
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96(37):e7752
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,骆洋
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腹腔镜结直肠手术中并发症的预防与处理
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中华腔镜外科杂志
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2017
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6(10): 347-350
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Yu-Hai Bian,
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Investigation of the bioequivalence of two lansoprazole formulations in healthy Chinese volunteers after a single oral administration
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Artif Cells Nanomed Biotechnol
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2017
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45(7):1425-1430
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Yang Luo, Shi-Yong Yu, Jian-Jun Chen, Jun Qin, Yi-Er Qiu,, Min Chen
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MiR-27b directly targets Rab3D to inhibit the malignant phenotype in colorectal cancer
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Oncotarget
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2017
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9(3):3830-3841
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骆洋, 秦骏, 陈建军, 俞旻皓, 秦绍岚, 仇伊尔,
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腹腔镜直肠癌手术中保留左结肠动脉与否临床对比研究
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中国实用外科杂志
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2017
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37(6):660-664
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Ye GY, Luo Y, Qin SL, Mu YF,
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High expression of Flotillin-2 is associated with poor prognosis in Chinese patients with colorectal cancer
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Int J Clin Exp Pathol.
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2016
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9(2): 1752-1757.
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Zheng-Shi Wang,, Yu-Hai Bian, Yi-Fei Mu, Shao-Lan Qin, Min-Hao Yu, Jun Qin
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MicroRNA-187 inhibits tumor growth and invasion by directly targeting CD276 in colorectal cancer.
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Oncotarget
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2016
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7(28):44266-44276.
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骆洋,秦骏,陈建军,俞旻皓,秦绍岚,仇伊尔,
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腹腔镜直肠癌手术中保留左结肠动脉与否临床对比研究
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中国实用外科杂志
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2016
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6(37):660-664
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Yang Luo, Guang-Yao Ye, Shao-Lan Qin, Yi-Fei Mu, Lei Zhang, Yang Qi, Yi-Er Qiu, Min-Hao Yu,
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High expression of Rab3D predicts poor prognosis and associates with tumor progression in colorectal cancer
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Int J Biochem Cell Biol.
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2016
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75 : 53–62.
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Min-Hao Yu, Yi-Fei Mu, Shao-Lan Qin, Yi-Er Qiu, Ran Cui,
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Odontogenic ameloblast-associated protein (ODAM) inhibits human colorectal cancer growth by promoting PTEN elevation and inactivating PI3K/AKT signaling.
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Biomed Pharmacother.
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2016
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84:601-607.
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仇伊尔,
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结肠直肠癌免疫治疗的研究进展
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外科理论与实践
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2016
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21(5):439-442
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秦绍岚,俞旻皓,慕逸飞,祁洋,仇伊尔,骆洋,崔然,
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全结肠系膜切除术在右半结肠癌根治术中应用的疗效
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中华胃肠外科杂志
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2016
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19(10):1101-1106.
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Zhang Y, Luo Y, Qin SL, Mu YF, Qi Y, Yu MH,
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The Clinical impact of ICOS signal in colorectal cancer patients
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Oncoimmunology.
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2016
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5(5):e1141857.
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慕逸飞,骆洋,卞正乾,俞旻皓,秦绍岚,
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ECT2基因在结肠直肠癌组织中的表达及意义
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外科理论与实践
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2016
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21(5):395-399
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骆洋,秦绍岚,俞旻皓,慕逸飞,王正实,王少华,
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多磷酸肌醇-5-磷酸酶Ⅱ通过影响AKT表达调控结直肠癌增殖和侵袭
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中华消化杂志
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2016
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36（1）：49-52.
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Feng Guo, Yang Luo, Yi-Fei Mu, Shao-Lan Qin, Yang Qi, Yi-Er Qiu,
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miR-193b directly targets STMN1 and inhibits the malignant phenotype in colorectal cancer.
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Am J Cancer Res
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2016
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6(11):2463-2475.
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俞旻皓,王正实,秦绍岚,慕逸飞,
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腹腔镜监控下（LMCP）息肉摘除术对比常规肠镜下息肉切除的随机对照临床研究
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现代医学生物进展
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2015
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15(10): 1858-1861
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Yang Luo, Shao-Lan Qin, Min-Hao Yu, Yi-Fei Mu, Zheng-Shi Wang,
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Prognostic value of regulator of G-protein signaling 6 in colorectal cancer
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biomedicine & pharmacotherapy
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2015
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76:147-152
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Min-Hao Yu, Yang Luo, Shao-Lan Qin,
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Increased expression of Rab5A predicts metastasis and poor prognosis in colorectal cancer patients
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International Journal of Clinical and Experimental Pathology
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2015
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8(6):6974-6980
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骆洋, 卞正乾, 叶光耀, 俞旻皓, 王正实, 秦绍岚, 慕逸飞,
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溶酶体相关４次跨膜蛋白Ｂ对结直肠癌增殖和侵袭的影响
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中华胃肠外科
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2015
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18 (6): 606-610
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Zhang C,
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Consumption of beer and colorectal cancer incidence a meta-analysis of observational studies
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Cancer Causes Control
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2015
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26(4):549-60
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曹冬兴,
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基于3T3-L1细胞株的人类ADRB1基因稳定过表达模型的构建
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现代肿瘤医学
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2015
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23(24): 3545-3548
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Yang Luo, Guang-Yao Ye, Shao-Lan Qin, Min-Hao Yu, Yi-Fei Mu,
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ATAD2 Overexpression Identifies Colorectal Cancer Patients with Poor Prognosis and Drives Proliferation of Cancer Cells
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Gastroenterology Research and Practice
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2015
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2015:936564
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Min-Hao Yu, Yang Luo, Shao-Lan Qin, Zheng-Shi Wang, Yi-Fei Mu,
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Up-regulated CKS2 promotes tumor progression and predicts a poor prognosis in human colorectal cancer
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American Journal of Cancer Research
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2015
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5(9):2708-2718
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Cong ZJ,Hu LH,Xing JJ,Zhang W,Fu CG,Yu ED,
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Risk factors associated with sphincter-preserving resection in patients with low rectal cancer
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Int Surg
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2014
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99(4):330-7
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Cong ZJ,Hu LH,Xing JJ,Bian ZQ,Fu CG,Yu ED,Li ZS,
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Incidence and mortality of anastomotic dehiscence requiring reoperation after rectal carcinoma resection
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Int Surg
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2014
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99(2):112-9
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俞旻皓, 彭友多, 卞正乾, 王正实, 叶光耀, 骆洋,
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溃疡性结肠炎36例手术治疗分析
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中国临床医学
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2014
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21(6): 659-660
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俞旻皓,, 叶光耀, 卞正乾, 陈建军, 丛志杰, 王正实, 骆 洋
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反穿刺技术在完全腹腔镜结直肠切除术中的应用
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腹腔镜外科杂志
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2014
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19 (7): 497-500
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Wang Zhengshi,
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Coexisting primary central nervous system non-Hodgkin's lymphoma and colorectal adenocarcinoma: A case report
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Oncology Letters
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2014
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7(4):994-996
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Chen Xiaojing,Sun Kai,Jiao Shufan,Cai Ning,Zhao Xue,Zou Hanbing,Xie Yuexia,Wang Zhengshi,,Wei Lixin
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High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients
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Scientific Reports
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2014
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12(15);4:7481
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Cong Zhi-Jie,Hu Liang-Hao,Bian Zheng-Qian,Ye Guang-Yao,Yu Min-Hao,Gao Yun-He,Li Zhao-Shen,Yu En-Da,
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Systematic review of anastomotic leakage rate according to an international grading system following anterior resection for rectal cancer
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PLos One
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2013
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8(9):e75519-e75519
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Yu Minhao,,Qiao Zhongdong
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Expression and clinical significance of cyclin kinase subunit 2 in colorectal cancer
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Oncology Letters
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2013
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6(3):777-780
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,Bian Zhengqian,Wu Zhiyong
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miR-30a suppresses cell migration and invasion through downregulation of PIK3CD in colorectal carcinoma
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Cellular Physiology and Biochemistry
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2013
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31(2-3):209-218
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腹腔镜技术在便秘治疗中的应用
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中华胃肠外科杂志
|
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15 (12) :5-7
|
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, Xian Wen Dong, Qing Zheng, Jin Lu Tong, Zhi Hua Ran
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Factor V Leiden and thrombosis in patients with inflammatory bowel disease (IBD): Ameta-analysis
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Thrombosis Research
|
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128 (2011) :403-409
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卞正乾, 杨伟强,, 唐伟军, 秦骏, 陈建军, 吴志勇
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腹腔镜直肠前切除术治疗低位直肠癌的体会
|
外科理论与实践
|
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15（4 ）：438-440
|
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Weijun Tang,Tonghai Dou,,Zhiyong Wu
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Dysregulation of Claudin family genes
in colorectal cancer in a Chinese
population
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BioFactors
|
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37（1 ）:65-73
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腹腔镜结肠直肠癌手术现状及临床体会
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外科理论与实践
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15（4 ）：342-345
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