- 基本信息
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导师姓名：
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涂水平
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学科代码：
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100214
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性别：
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男
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学科名称：
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肿瘤学
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培养单位：
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附属仁济医院
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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肿瘤学 专业学位
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联系方式：
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15618573010
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专业领域代码：
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105121
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邮编：
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200127
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邮箱地址：
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tushuiping@yahoo.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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上海市医学会姑息治疗专业委员会 常委
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上海市浦东新区医学会肿瘤分会 副主任委员
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中国医药教育学会肺部肿瘤专业委员会常委 中国研究型医院乳腺癌专业委员会常委 上海市抗癌协会肺癌分子靶向和免疫治疗专业委员会委员、 上海市免疫学会遗传免疫分会委员
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上海市医学会肿瘤靶分子专业委员会 委员
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- 科研项目
| 81773259 | 特异性靶向抑制MDSC免疫治疗胃癌的作用研究 | 国家自然科学基金 |
2018-01~2021-12
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55万元
| 课题负责人 |
| 51CJ1043100 | 检测循环肿瘤干细胞的免疫荧光-原位杂交新技术的建立和应用研究 | 上海市科委 |
2015-07~2018-06
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60万元
| 课题负责人 |
| 91429307 | 白细胞介素在胃肠癌发生发展中的协作机制 | 国家自然基金重大研究计划集成项目 |
2015-01~2018-12
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70万元
| 子课题负责人 |
| 81472727 | RSPO3 调节结肠癌干细胞和肿瘤生长的作用及机制 | 国家自然科学基金 |
2015-01~2018-12
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63万元
| 课题负责人 |
| 81272403 | 骨髓来源的肌成纤维母细胞促进胃癌转移的机制研究 | 国家自然科学基金 |
2013-01~2016-12
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70万元
| 课题负责人 |
| 81172159 | XAF1 抑制肿瘤转移的作用及机制研究 | 国家自然科学基金 |
2012-01~2015-12
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60万元
| 课题负责人 |
| 91029718 | 炎症介质IL-1beta介导的非可控性炎症诱发胃干细胞恶性转化的分子机制 | 国家自然科学基金 |
2011-01~2013-12
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60万元
| 课题负责人 |
- 学术论文
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Cheng XJ, Lin JC, Ding YF, Zhu L, Ye J,
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Survivin inhibitor YM155 suppresses gastric cancer xenograft growth in mice without affecting normal tissues
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Oncotarget
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2016
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7(6):7096-109
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Zhu L, Cheng X, Shi J, Lin J, Chen G, Jin H, Liu AB, Pyo H, Ye J, Zhu Y, Wang H, Chen H, Fang J, Cai L, Wang TC, Yang CS,
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Crosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis
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Oncogene
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2016
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35(41):5388-5399.
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Zhu L, Cheng X, Shi J, Lin J, Chen G, Jin H, Liu AB, Pyo H, Ye J, Zhu Y, Wang H, Chen H, Fang J, Cai L, Wang TC, Yang CS,
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rosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis.
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Oncogene
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2016
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25:20 Epub
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Zhu LM, Shi DM, Dai Q, Cheng XJ, Yao WY, Sun PH, Ding Y, Qiao MM, Wu YL, Jiang SH,
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Tumor suppressor XAF1 induces apoptosis, inhibits angiogenesis and inhibits tumor growth in hepatocellular carcinoma.
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Oncotarget
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2014
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2014;5(14):5403-15
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Zhu L, Cheng XJ, Ding YF, Shi JD, Jin Y, Wang H, Wu YL, Ye J, Lu B, Wang TC, Yang CS,
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Zhu L, Cheng XJ, Ding YF, Shi JD, Jin Y, Wang H, Wu YL, Ye J, Lu B, Wang TC, Yang CS, TU SP*. Bone marrow-derived myofibroblasts promote gastrointestinal tumorigenesis through the IL-6/JAK2/STAT3 pathway. Cancer Letters 2014;343(1):80-9.
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Cancer Letters
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2014
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2014;343(1):80-9.
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, Jin HY, Jin DS, Zhu LM, Suo Y, Lu G, Wang TC, Yang CS.
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Curcumin induces the differentiation of myeloid-derived suppressor cells and inhibits their interaction with cancer cells and related tumor growth
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Cancer Prevention Research
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2012
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5(2):205-15
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Sun PH, Zhu LM, Qiao MM, Zhang YP, Jiang SH, Wu YL,
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The XAF1 tumor suppressor induces autophagic cell death via upregulation of Beclin-1 and inhibition of Akt pathway
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Cancer Letter
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2011
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310(2):170-80
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, Quante M, Bhagat G, Takaishi S, Cui G, Yang XD, Muthuplani S, Shibata W, Fox JG, Pritchard DM, Wang TC
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IFN-γ inhibits gastric carcinogenesis by inducing epithelial cell autophagy and T-cell apoptosis
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Cancer Research
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2011
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71(12):4247-59
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Xue Z, Sun PH, Zhu LM, Jiang SH, Qiao MM, Chi AL,
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deno-associated virus-mediated survivin mutant Thr34Ala cooperates with oxaliplatin to inhibit tumor growth and angiogenesis in colon cancer
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Oncology Report
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2011
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25(4):1039-46
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Quante M,, Tomita H, Gonda T, Wang SS, Takashi S, Baik GH, Shibata W, Diprete B, Betz KS, Friedman R, Varro A, Tycko B, Wang TC
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Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth
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Cancer Cell
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2011
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19(2):257-72
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, Sun YW, Cui JT, Zou B, Lin MC, Gu Q, Jiang SH, Kung HF, Korneluk RG, Wong BC
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Tumor suppressor XAF1 cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression
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Cancer
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2010
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116:1252-63
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, Wai-Yn Sun R, Lin MC, Tao Cui J, Zou B, Gu Q, Kung HF, Che CM, Wong BC
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Gold (III) porphyrin complexes induce apoptosis and cell cycle arrest and inhibit tumor growth in colon cancer
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Cancer.
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2009
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115 (19):4459-69
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, Liston P, Cui JT, Lin MC, Jiang XH, Yang Y, Gu Q, Jiang SH, Lum CT, Kung HF, Korneluk RG, Wong BC
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Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer
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Int J Cancer
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2009
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125(3):688-97
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, Chi AL, Ai W, Takaishi S, Dubeykovskaya Z, Quante M, Fox JG, Wang TC
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p53 inhibition of AP1-dependent TFF2 expression induces apoptosis and inhibits cell migration in gastric cancer cells
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Am J Physiol Gastrointest Liver Physiol
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2009
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297(2):G385-96
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, Bhagat G, Cui G, Takaishi S, Kurt-Jones EA, Rickman B, Bjorkdahl O, Fox JG, Wang TC
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Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
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Cancer Cell
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2008
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14(5):408-19
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, Chi AL, Lim S, Cui G, Dubeykovskaya Z, Ai W, Fleming JV, Takaishi S, Wang TC
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Gastrin regulates the TFF2 promoter through gastrin-responsive cis-acting elements and multiple signaling pathways
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Am J Physiol Gastrointest Liver Physiol
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2007
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292(6):G1726-37
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, Cui JT, Liston P, Huajiang X, Xu R, Lin MC, Zhu YB, Zou B, Ng SS, Jiang SH, Xia HH, Wong WM, Chan AO, Yuen MF, Lam SK, Kung HF, Wong BC.
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Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant
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Gastroenterology
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2005
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128(2): 361-375
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Jiang XH,, Cui JT, Lin MC, Xia HX, Wong WM, Chan AO, Yuen MF, Jiang SH, Lam SK, Kung HF, Weinstein IB, Wong BC
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Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant
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Cancer Research
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2004
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64(16):5787-94
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, Jiang XH, Lin MC, Cui JT, Yang Y, Lum CT, Zou B, Zhu YB, Jiang SH, Wong WM, Chan AO, Yuen MF, Lam SK, Kung HF, Wong BC.
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Inhibition of survivin suppresses in vivo tumorigenecity and angiogenesis in gastric cancer
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Cancer Research
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2003
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63(22): 7724-32
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