- 基本信息
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导师姓名：
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李宁丽
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学科代码：
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100100
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性别：
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女
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学科名称：
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基础医学
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培养单位：
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基础医学院
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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联系方式：
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专业领域代码：
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邮编：
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邮箱地址：
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Ninglixiaoxue57@163.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
- 科研项目
| 12JC1407700 | Cyr61上调IL-1b/Chemerin参与类风关骨破坏机制及免疫干预研究 | 上海市科学技术委员会 |
2013-01~2015-12
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40万元
| 课题负责人 |
| 12DZ1941802 | SAA1β+/+纯合子基因型诊断试剂盒的实验室评估与性能优化 | 上海市科学技术委员会 |
2013-01~2015-12
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60万元
| 子课题负责人 |
| 20130073110003 | Cyr61与银屑病发生发展的相关性及其机制研究 | 教育部高等学校博士学科点专项科研基金资助（博导类） |
2013-01~2016-12
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12万元
| 课题负责人 |
| 12JC1407702 | 自拟蠲痹补肾方对类风湿关节炎临床疗效与作用机理研究 | 上海市科学技术委员会 |
2013-01~2015-12
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15万元
| 子课题负责人 |
| 81172856 | 探讨IL-17/Cyr61通路介导的类风关炎症与组织损伤新机制 | 国家自然基金 |
2012-01~2015-12
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60万元
| 课题负责人 |
| 81072468 | IL-17上调类风关滑膜细胞Cyr61表达时转录因子作用和调控研究 | 国家自然科学基金委员会 |
2011-01~2013-12
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31万元
| 课题负责人 |
| 2010CB529103 | 类风湿关节炎发病的免疫学机制及其干预策略的研究 | 科技部 |
2010-01~2015-12
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180万元
| 课题参与人 |
- 学术论文
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Yue Sun, Jie Zhang, Rongfen Huo, Tianhang Zhai, Huidan Li, Pinru Wu, Xianjin Zhu, Zhou Zhou, Baihua Shen,
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Paeoniflorin inhibits skin lesions in imiquimod-induced psoriasis-like mice by down regulating inflammation
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International Immunopharmacology
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2015
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24:392–399
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Xianjin Zhu, Yanfang Song, Rongfen Huo, Jie Zhang, Songtao Sun,Yong He, Huali Gao, Miaojia Zhang, Xiaoxuan Sun, Tianhang Zhai,Huidan Li, Yue Sun, Zhou Zhou, Baihua Shen,Lianbo Xiao,
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Cyr61 participates in the pathogenesis of rheumatoid arthritis by promoting proIL-1 β production by fibroblast-like synoviocytes through an AKT-dependent NF- κ B signaling pathway
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Clinical Immunology
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2015
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157:187–197
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Jie Zhang, Huidan Li, Rongfen Huo, Tianhang Zhai, Haichuan Li, Yue Sun, Baihua Shen,
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Paeoni?orin selectively inhibits LPS-provoked B cell function.
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Journal of Pharmacological Sciences
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2015
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128:8-16
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Sun Y, Zhang J, Zhou Z, Wu P, Huo R, Wang B, Shen Z, Li H, Zhai T, Shen B, Chen X*,
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CCN1, a Pro-Inflammatory Factor, Aggravates Psoriasis Skin Lesions by Promoting Keratinocyte Activation
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Journal of Investigative Dermatology
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2015
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Journal of Investigative Dermatology advance online publication, 23 July 2015; doi:10.1038/jid.2015.231
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Xianjin Zhu, Jie Zhang, Rongfen Huo, Jinpiao Lin, Zhou Zhou,Yue Sun, Pinru Wu, Huidan Li, Tianhang Zhai, Baihua Shen,
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Evaluation of the efficacy and safety of different tripterygium preparations on collagen-induced arthritis in rats
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Journal of Ethnopharmacology
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2014
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158:283-290
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Jinpiao Lin, Rongfen Huo, Lianbo Xiao, Xianjin Zhu, Jun Xie, Songtao Sun, Yong He, Jie Zhang, Yue Sun, Zhou Zhou, Pinru Wu, Baihua Shen, Dangsheng Li,
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A Novel p53-miR-22-Cyr61 Axis in Synovial Cells Regulates Inflammation in Rheumatoid Arthritis
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Arthritis & Rheumatology
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2014
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66: 49-59
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Xianjin Zhu, Lianbo Xiao, Rongfen Huo, Jie Zhang, Jinpiao Lin, Jun Xie, Songtao Sun, Yong He, Yue Sun, Zhou Zhou, Baihua Shen,
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Cyr61 Involved in Neutrophil Infiltration in Joints via Inducing IL-8 Production by Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
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Arthritis Research & Therapy
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2013
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15:R187
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Jun Shi, Zhou Zhou, Wen Di,
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Correlation of CD44v6 expression with ovarian cancer progression and Recurrence
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BMC Cancer
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2013
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13:182 doi:10.1186/1471-2407-13-182
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Jinpiao Lin, Rongfen Huo, Li Wang, Zhou Zhou, Yue Sun, Baihua Shen, Rongfang Wang,
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A novel anti-Cyr61 antibody inhibits breast cancer growth and metastasis in vivo
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Cancer Immunology Immunotherapy
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2012
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61:677-687
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Jinpiao Lin,Lianbo Xiao, Guilin Ouyang, Yu Shen, Rongfen Huo, Zhou Zhou, Yue Sun, Xianjin Zhu, Jie Zhang, Baihua Shen,
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Total Glucosides of Paeony Inhibits Th1/Th17 Cells via Decreasing Dendritic Cells Activation in Rheumatoid Arthritis
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Cellular Immunology
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2012
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280: 156-163
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Jinpiao Lin, Zhou Zhou, Rongfen Huo, Lianbo Xiao, Guilin Ouyang,Li Wang, Yue Sun, Baihua Shen, Dangsheng Li,
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Cyr61 Promotes Th17 Differentiation through Inducing IL-6 Production by Fibroblast-Like Synoviocytes in Rheumatoid Arthritis.
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Journal of Immunology
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2012
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188(11):5776-5784
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Zhou Zhou, Jinpiao Lin, Rongfen Huo, Wenkang Huang, Jian Zhang, Li Wang, Yue Sun, Baihua Shen,
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Total Glucosides of Paeony Attenuated Functional Maturation of Dendritic Cells via Blocking TLR4/5 Signaling in vivo.
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International Immunopharmacology
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2012
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12:275-282
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Li Wang, Jinpiao Lin, Zhou Zhou, Rongfen Huo, Baihua Shen,Yue Sun,
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Up-regulation of Th17 cells may underlie inhibition of Treg development caused by immunization with activated syngeneic T cells
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PloS ONE
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2011
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6(11):27289-27300
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Yan Zhang, Li Wang, Dangsheng Li,
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Taming regulatory T cells by autologous T cell immunization: a potential new strategy for cancer immune therapy
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Int Immuunopharm
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2009
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9:593-595
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Qiuyu Zhang, Juanjuan Wu, Qi Cao, Lianbo Xiao, Li Wang, Dongyi He, Guilin Ouyang, Jinpiao Lin, Baihua Shen, Yuan Shi, Yan Zhang, Dangsheng Li,
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A Critical Role of Cyr61 in IL-17-dependent Proliferation of Fibroblast-like Synoviocytes in Rheumatoid Arthritis
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Arthritis & Rheumatology
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2009
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60(12):3602-3612
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Fang Dua,Li Wang,Yan Zhang, Wei Jiang, Huiming Sheng, Qi Cao,Juanjuan Wu, Baihua Shen, Tianwei Shen, Jingwu Z. Zhang,Chunde Bao, Dangsheng Li,
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Role of GADD45β in the regulation of synovial fluid T cell apoptosis in rheumatoid arthritis
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Clinical Immunology
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2008
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128:238-247
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Huiming Sheng, Ying Wang, Yuqing Jin, Qiuyu Zhang, Yan Zhang, Li Wang, Baihua Shen, Shuo Yin, Wei Liu, Lei Cui,
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A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1
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Cell Reseaerch
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2008
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18:846-857
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Qi Cao, Li Wang, Fang Du, Huiming Sheng, Yan Zhang, Juanjuan Wu, Baihua Shen, Tianwei Shen, Jingwu Zhang, Dangsheng Li,
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Down-regulation of CD4+CD25+ regulatory T cells may underlie enhanced anti-tumor immunity caused by immunization with activated autologous T cells
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Cell Reseaerch
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2007
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17:627-637
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Li Wang,Fang Du, Qi Cao, Huiming Shen, Baihua Shen, Yan Zhang, Yingna Diao, Jingwu Zhang,
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Immunization with Autologous T Cells Enhances in vivo Anti-tumor Immune Responses mediated by up-regulation of GADD45β
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Cell Reseaerch
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2006
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16:702-712
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