• 基本信息
    导师姓名： 于晓巍 学科代码： 100210
    性别： 男 学科名称： 外科学
    培养单位： 附属第六人民医院 三级学科 骨外
    导师类型： 博士生导师 专业领域名称： 外科学 专业学位
    联系方式： yuxw@sjtu.edu.cn 专业领域代码： 105111
    邮编： yuxw@sjtu.edu.cn 邮箱地址： yuxw@sjtu.edu.cn
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    中国老年保健协会健康中国行动推进工作委员会副主任委员
    国际矫形与创伤外科学会(SICOT)中国部创伤学会委员
    《中华创伤杂志英文版》通讯编委
    白求恩公益基金会老年髋部骨折专业委员会委员
    上海市医学会骨科专科分会委员
    Annals of Translational Medicine 编委
    Medicine Research高级编辑委员会成员
    上海市医学会创伤专科分会委员
    中国医疗保健国际交流促进会创伤学会委员
    中华医学会骨科学分会运动医学学组青年委员
    中华医学会创伤学分会青年委员
    中华医学会医学工程学分会数字骨科学组工作委员会（数字骨科创伤与关节工作委员会）委员
    General Chemistry高级编辑委员会成员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    82372387激素性股骨头坏死中巨噬细胞-骨细胞间的时空通讯及靶点意义国自然面上项目 2024-01~2027-01 49万元  课题负责人
    22DZ2203600基于双平面数字X射线图像和人工智能赋能的扁平足检测技术标准研发上海市2022年度“科技创新行动计划”技术标准项目 2022-08~2024-07 15万元  课题负责人
    PKJ2019-Y02基于仿真分析软件为主体的人工智能用于单间室膝关节炎的截骨方案优化设计上海市浦东新区科技发展基金民生科研专项资金医疗卫生项目 2019-12~2022-11 36万元  课题负责人
    SHDC12019X24Anybody软件结合人工智能辅助截骨方案优化设计治疗内侧间室膝关节炎上海申康医院发展中心临床科技创新项目 2019-11~2022-11 30万元  课题负责人
    DYZD201803Anybody软件在闭合楔形胫骨高位截骨手术中的应用上海市第六人民医院东院临床研究重点专项 2019-01~2021-12 15万元  课题负责人
    81873993双控释骨支架的制备及其在感染性骨缺损中的应用及机制研究国自然面上项目 2019-01~2022-12 57万元  课题负责人
    2018BR38上海市卫生计生系统优秀学科带头人培养计划上海市卫计委 2018-09~2021-06 45万元  课题负责人
    81572155程序释放VEGF/BMP载药系统强化磷酸钙治疗股骨头缺血性坏死的研究国家自然科学基金委员会 2016-01~2019-12 68.4万元  课题负责人
    ZY3-CCCX-3-3044人参果治疗骨质疏松症及骨质疏松骨折的应用研究上海市进一步加快中医药事业发展三年行动计划（2014年-2016年） 2014-09~2016-12 50万元  课题负责人
    14ZR1431800同轴纳米PCL/PVA纤维载红霉素强化磷酸钙治疗骨髓炎的实验研究上海市自然科学基金项目 2014-07~2017-06 10万元  课题负责人
    81071487组织工程软骨-骨复合移植物的仿生构建国家自然科学基金面上项目 2011-01~2013-12 33万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Shan H, Lin Y, Yin F, Pan C, Hou J, Wu T, Xia W, Zuo R, Cao B, Jiang C, Zhou Z,  Effects of astragaloside IV on glucocorticoid-induced avascular necrosis of the femoral head via regulating Akt-related pathways  Cell Prolif  2023  e13485 
    Zhou Z, Chen Y, Min HS, Wan Y, Shan H, Lin Y, Xia W, Yin F, Jiang C,  Merlin functions as a critical regulator in Staphylococcus aureus-induced osteomyelitis  J Cell Physiol  2022  237(1):815-823 
    Wang F, Min HS, Shan H, Yin F, Jiang C, Zong Y, Ma X, Lin Y, Zhou Z,  IL-34 aggravates steroid-induced osteonecrosis of the femoral head via promoting osteoclast differentiation  Immune Netw  2022  22(3):e25 
    Liu X, Min HS, Chai Y,, Wen G  Masquelet technique with radical debridement and alternative fixation in treatment of infected bone nonunion  Front Surg  2022  9:1000340 
    Jiang C, Lin Y, Shan H, Xia W, Pan C, Wang N, Zhou L, Gao Y, Zhou Z,  miR-146a Protects against Staphylococcus aureus-Induced Osteomyelitis by Regulating Inflammation and Osteogenesis  ACS Infect Dis  2022  8(5):918-927 
    Zhang W, Lin Y, Zong Y, Ma X, Jiang C, Shan H, Xia W, Yin L, Wang N, Zhou L, Zhou Z,  Staphylococcus aureus Infection Initiates Hypoxia-Mediated Transforming Growth Factor-β1 Upregulation to Trigger Osteomyelitis  mSystems  2022  7(4):e0038022 
    Wang M, Min HS, Shan H, Lin Y, Xia W, Yin F, Jiang C,  Bone morphogenetic protein 2 controls steroid-induced osteonecrosis of the femoral head via directly inhibiting interleukin-34 expression  J Mol Endocrinol  2021  68(1):1-9 
    Zhang W, Hu C, Zhang C, Luo C, Zhong B,  MiRNA-132 regulates the development of osteoarthritis in correlation with the modulation of PTEN/PI3K/AKT signaling  BMC Geriatr  2021  21(1):175 
    Zong Y, Shan H, Yin F, Ma X, Jiang C, Wang N, Zhou L, Lin Y, Zhou Z,  Ddb1-Cullin4-Associated-Factor 1 in Macrophages Restricts the Staphylococcus aureus-Induced Osteomyelitis  J Inflamm Res  2021  14:1667-1676 
    Xia W, Li N, Shan H, Lin Y, Yin F,, Zhou Z  Gallium Porphyrin and Gallium Nitrate Reduce the High Vancomycin Tolerance of MRSA Biofilms by Promoting Extracellular DNA-Dependent Biofilm Dispersion  ACS Infect Dis  2021  . 
    Liu Y, Shan H, Zong Y, Lin Y, Xia W, Wang N, Zhou L, Gao Y, Ma X, Jiang C,  IKKe in osteoclast inhibits the progression of methylprednisolone-induced osteonecrosis  Int J Biol Sci  2021  17(5):1353-1360 
    Jiang C, Zhou Z, Lin Y, Shan H, Xia W, Yin F, Wang N, Zhou L, Gao Y,  Astragaloside IV ameliorates steroid-induced osteonecrosis of the femoral head by repolarizing the phenotype of pro-inflammatory macrophages  Int Immunopharmacol  2021  107345 
    Jiang F, Zong Y, Ma X, Jiang C,Shan H, Lin Y, Xia W, Yin F, Wang N, Zhou L, Zhou Z,  MiR-26a attenuated bone-specific insulin resistance and bone quality in diabetic mice  Mol Ther Nucleic Acids  2020  20:459-467 
    Zhang W, Liu J, Shan H, Yin F, Zhong B, Zhang C,  Machine learning-guided evolution of BMP-2 knuckle Epitope-Derived osteogenic peptides to target BMP receptor II  J Drug Target  2020  1-9 
    Zhou Z, Lin Y, Pan C, Wang N, Zhou L, Shan H, Gao Y,  IL-15 deficiency alleviates steroid-induced osteonecrosis of the femoral head by impact osteoclasts via RANKL-RANK-OPG system  Immun Ageing  2020  17:19 
    Wu T, Yin F, Wang N, Ma X, Jiang C, Zhou L, Zong Y, Shan H, Xia W, Lin Y, Zhou Z,  Involvement of mechanosensitive ion channels in the effects of mechanical stretch induces osteogenic differentiation in mouse bone marrow mesenchymal stem cells  J Cell Physiol  2020  doi: 10.1002/jcp.29841 
    Zhang W, Zhang C, Hu C, Luo C, Zhong B,  Circular RNA-CDR1as acts as the sponge of microRNA-641 to promote osteoarthritis progression  J Inflamm (Lond)  2020  17:8 
    Jiang C, Xia W, Wu T, Pan C, Shan H, Wang F, Zhou Z,  Inhibition of microRNA-222 up-regulates TIMP3 to promotes osteogenic differentiation of MSCs from fracture rats with type 2 diabetes mellitus  J Cell Mol Med  2020  24(1):686-694 
    Jiang F, Shan H, Pan C, Zhou Z, Cui K, Chen Y, Zhong H, Lin Z, Wang N, Yan L,  ATP6V1H facilitates osteogenic differentiation in MC3T3-E1 cells via Akt/GSK3β signaling pathway  Organogenesis  2019  15(2):43-54 
    Jiang F, Yin F, Lin Y, Xia W, Zhou L, Pan C, Wang N, Shan H, Zhou Z,  The promotion of bone regeneration through CS/GP-CTH/antagomir-133a/b sustained release system  Nanomedicine  2019  24:102116 
    Pan C, Shan H, Wu T, Liu W, Lin Y, Xia W, Wang F, Zhou Z,  20(S)-Protopanaxadiol Inhibits Titanium Particle-Induced Inflammatory Osteolysis and RANKL-Mediated Osteoclastogenesis via MAPK and NF-κB Signaling Pathways  Front Pharmacol  2019  9:1538 
    Zhou Z, Pan C, Wang N, Zhou L, Shan H, Gao Y,  A high-fat diet aggravates osteonecrosis through a macrophage-derived IL-6 pathway  Int Immunol  2019  31(4):263-273 
    Pan C, Zhou Z,  Coatings as the useful drug delivery system for the prevention of implant-related infections  J Orthop Surg Res  2018  13(1):220 
    Zhou Z, Seta J, Markel DC, Song W, Yurgelevic SM,, Ren W.  Release of vancomycin and tobramycin from polymethylmethacrylate cements impregnated with calcium polyphosphate hydrogel  J Biomed Mater Res B Appl Biomater.  2018  106(8):2827-2840 
    Chen F, Ni Y, Liu B, Zhou T, Yu C, Su Y, Zhu X,, Zhou Y  Self-crosslinking and injectable hyaluronic acid/RGD-functionalized pectin hydrogel for cartilage tissue engineering  Carbohydr Polym  2017  166:31-44 
    Zhou W, Yuan T, Gao Y, Yin P, Liu W, Pan C, Liu Y,  IL-1β-induces NF-κB and upregulates microRNA-372 to inhibit spinal cord injury recovery  J Neurophysiol  2017  117(6):2282-2291 
    Wang N, Wang F, Gao Y, Zhou Z, Liu W, Pan C, Yin P, Tang M,  Solanum Muricatum Promotes Osteogenic Differentiation of Rat Bone Marrow Stromal Cells  J Food Sci  2017  82(7):1775-1780 
    Zhou Z, Pan C, Lu Y, Gao Y, Liu W, Yin P,  Combination of Erythromycin and Curcumin Alleviates Staphylococcus aureus Induced Osteomyelitis in Rats  Front Cell Infect Microbiol  2017  7:379 
    Wang F, Wang N, Gao Y, Zhou Z, Liu W, Pan C, Yin P,, Tang M  β-Carotene suppresses osteoclastogenesis and bone resorption by suppressing NF-κB signaling pathway  Life Sci  2017  174:15-20 
    Wang F, Guan X, Wu T, Qiao J, Han Z, Wu J,, You Q  Acellular Endocardium as a Novel Biomaterial for the Intima of Tissue-Engineered Small-Caliber Vascular Grafts  Artif Organs  2016  40(12):E253-E265 
    Chen C, Lu J, Yu Q, Xiao JR, Wei HF, Song XJ, Ge JB, Tao WD, Qian R,, Zhao J  Expression of CDc6 after acute spinal cord injury in adult rats  Neuropeptides  2016  56:59-67 
    Chen F, Yu S, Liu B, Ni Y, Yu C, Su Y, Zhu X,, Zhou Y, Yan D  An Injectable Enzymatically Crosslinked Carboxymethylated Pullulan/Chondroitin Sulfate Hydrogel for Cartilage Tissue Engineering  Sci Rep  2016  6:20014 
    Zhao J, Chen C, Xiao JR, Wei HF, Zhou XH, Mao XX, Zhang WD, Qian R, Chen XL, He MQ,, Zhao J  An Up-regulation of IRF-1 After a Spinal Cord Injury: Implications for Neuronal Apoptosis  J Mol Neurosci  2015  57(4):595-604 
    Wu T, Zhou Z, Ren W, He Z,, Huang Y  Reinforcement of A New Calcium Phosphate Cement with RGD-chitosan-fiber  J Biomed Mater Res A  2014  102(1): 68-75 
    , Ai ZS, Gao YS, Zhang CQ  Blood loss closely correlates with body mass index in total hip arthroplasty performed through direct lateral approach  Saudi Med J  2013  34(7):709-13 
    , Jiang W, Pan Q, Wu T, Zhang Y, Zhou Z, Du D  Umbrella-shaped, memory alloy femoral head support device for treatment of avascular osteonecrosis of the femoral head  Int Orthop  2013  37(7):1225-32 
    , Wen H, Cao J, Sun B, Ding T, Li M, Wu H, Long L, Cheng X, Xu G, Zhang F  Temporal and Spatial Expression of KIF3B after Acute Spinal Cord Injury in Adult Rats  J Mol Neurosci  2013  49(2):387-94 
    Song W,, Markel DC, Shi T, Ren W  Coaxial PCL/PVA electrospun nanofibers: osseointegration enhancer and controlled drug release device  Biofabrication  2013  5(3):035006 
    Wu T, Zhang Q, Ren W, Yi X, Zhou Z, Peng X,, Lang M  Controlled release of gentamicin from gelatin/genipin reinforced beta-tricalcium phosphate scaffold for the treatment of osteomyelitis  J Mater Chem B  2013  3304-3313 
    , Zhao X, Wu T, Zhou Z, Gao Y, Wang X, Zhang CQ  Inhibiting wear particles-induced osteolysis with naringin  Int Orthop  2013  37(1):137-43 
    , Tang M, Zhou Z, Peng X, Wu T, Sun Y  Minimally invasive treatment for pubic ramus fracture combined with sacroiliac joint complex injury  Int Orthop  2013  37(8):1547-54 
    Wu T, Hua X, He Z, Wang X,, Ren WP  The bactericidal and biocompatible characteristics of reinforced calcium phosphate cements  Biomed Mater  2012  7(4):045003 
    , Zhong Y, Zhu Z, Wu T, Shen A, Huang Y  Increased expression of nitric oxide synthase interacting protein (NOSIP) following traumatic spinal cord injury in rats  J Mol Histol  2012  43(6):661-8 
    Zhong Y, Huang Y, Cao J, Lu X, Feng M, Shen G, Shen A,  Increase in phosphorylation of PDK1 and cell survival after acute spinal cord injury  J Neurol Sci  2012  320(1-2):38-44 
    Xie XH,, Zeng SX, Du RL, Hu YH, Yuan Z, Lu EY, Dai KR, Tang TT  Enhanced osteointegration of orthopaedic implant gradient coating composed of bioactive glass and nanohydroxyapatite  J Mater Sci Mater Med  2010  21(7):2165-73 
    , Xie XH, Yu ZF, Tang TT  Augmentation of Screw Fixation with Injectable Calcium Sulfate Bone Cement in Ovariectomized Rats  J Biomed Mater Res B Appl Biomater  2009  89(1):36-44