• 基本信息
    导师姓名： 李百文 学科代码： 100201
    性别： 男 学科名称： 内科学
    培养单位： 附属第一人民医院 三级学科 消化系病
    导师类型： 博士生导师 专业领域名称： 内科学 专业学位
    联系方式： 专业领域代码： 105101
    邮编： 邮箱地址： libaiwen@163.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    上海市消化内镜学会委员，上海市消化内镜学会EUS学组副组长，上海市消化内镜学会ERCP学组委员，日本消化管学会 (JGA)国际委员，世界华人内镜医师协会委员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    82270568EGR1通过抑制幽门肌间神经丛中氮能神经元/nNOS信号网络参与糖尿病胃轻瘫发生的机制研究国家自然科学基金面上项目 2023-01~2026-12 50万元  课题负责人
    SHDC2022CRT011胃转流支架系统研发及对非酒精性脂肪肝的临床转化研究3. 上海市申康“促进市级医院临床技能与临床创新三年行动”计划 2023-01~2025-12 200万元  子课题负责人
    22Y11907800经口内镜下胃幽门肌切开术(G-POEM)治疗胃轻瘫的有效性与安全性研究 上海市科委“科技创新行动“计划 2022-07~2025-06 30万元  课题负责人
    81570475高脂饮食诱导高脱氧胆酸通过内质网应激损害潘氏细胞功能导致肠道菌群紊乱的机制研究国家自然科学基金面上项目 2016-01~2019-12 70万元  课题参与人
    81572316miR-21通过Ras-MAPKs信号通路介导负调控Net基因表达在胰腺导管腺癌发生中的作用机制研究国家自然科学基金面上项目 2016-01~2019-12 53万元  课题负责人
    81470904一种新型的溶石药物控释金属支架治疗难治性胆总管结石的实验研究国家自然科学基金面上项目 2015-01~2018-12 73万元  课题参与人
    YG2014MS24镁合金生物可降解胆管支架的研制及在胆道良性狭窄疾病中的应用研究上海交通大学医工交叉面上项目 2015-01~2017-12 15万元  课题负责人
    14411966900镁合金生物可降解胆管支架的研制及在胆道良性狭窄疾病中的应用研究上海市科委医学引导面上项目 2014-07~2017-12 20万元  课题负责人
    11ZR1429000胰腺癌中Net基因差异表达的分子机制及功能研究的初步探讨上海市自然科学基金面上项目 2011-01~2013-12 10万元  课题负责人
    81072006基于胰腺癌内皮细胞的 miRNAs 差异表达及治疗性 AngiomiRs 的筛选国家自然科学基金面上项目 2011-01~2013-12 30万元  课题参与人
    10PJ1408500MicroRNA-196与胰腺癌侵袭转移关系的实验研究上海市浦江人才计划 2010-04~2013-04 15万元  课题参与人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Xie N, Fan X, Xie H, Lu J, Yu L, Liu H, Wang H, Yin X,  Preoperative Extrapancreatic Extension Prediction in Patients with Pancreatic Cancer Using Multiparameter MRI and Machine Learning-Based Radiomics Model  Acad Radiol  2023  2023;30(7):1306-1316. 
    Ni J, Peng K, Yu L, Xi H, Luo S, Xu K, Xia Y, Xie N, Lu J, Lu L, Hu D, Wan X,  Transpapillary Stenting Improves Treatment Outcomes in Patients Undergoing Endoscopic Transmural Drainage of Ductal Disruption-Associated Pancreatic Fluid Collections  Am J Gastroenterol  2023  2023;118(6):972-982 
    Xie N, Fan X, Chen D, Chen J, Yu H, He M, Liu H, Yin X,, Wang H  eritumoral and Intratumoral Texture Features Based on Multiparametric MRI and Multiple Machine Learning Methods to Preoperatively Evaluate the Pathological Outcomes of Pancreatic Cancer  J Magn Reson Imaging  2023  2023 Aug;58(2):379-391 
    Lu J, Yang P, Yu L, Xie N, Wu Y,  Identification of m7G-Related LncRNA Signature for Predicting Prognosis and Evaluating Tumor Immune Infiltration in Pancreatic Adenocarcinoma  Diagnostics (Basel)  2023  2023;13(10):1697 
    Chen D, Ren Y, Chen S, Jin Y, Xie H, Yu L, Peng K, Xia Y, Pan D, Lu J, Lu L, Wan X, Hu D,  The Wet Suction Technique Enhances the Diagnostic Efficacy and Aspirate Quality of EUS-FNA for Solid Lesions: A Multicenter Retrospective Study in China  J Clin Gastroenterol  2023  2023;57(4):417-422 
    Mao Y, Wan S,  "Homemade cap"-assisted ultrafine gastroscope for palliative stenting for extreme gastrojejunal anastomotic stenosis (with video)  Gastrointest Endosc  2023  S0016-5107(23)02686 
    Lu J, Yu L, Xie N, Wu Y,  METTL14 Facilitates the Metastasis of Pancreatic Carcinoma by Stabilizing LINC00941 in an m6A-IGF2BP2-Dependent Manner  J Cancer  2023  2023;14(7):1117-1131 
    Ni J, Xie N,  Endoscopic diagnosis of Santoriniceles with reverse pancreas divisum  Gastrointest Endosc  2022  2022;95(5):1015-1016 
    Xie H, Zhao Q, Yu L, Lu J, Peng K, Xie N, Ni J,  Circular RNA circ_0047744 suppresses the metastasis of pancreatic ductal adenocarcinoma by regulating the miR-21/SOCS5 axis  Biochem Biophys Res Commun  2022  2022;605:154-161 
    Fu S, Mao Y, Yu Y, Hu B,  A Novel Technique for Endoscopic Removal of a Large Foreign Body Incarcerated in the Colon Using a Modified Diameter-Adjustable Snare  Am J Gastroenterol  2022  2022;117(12):1906 
    Yu L, Lu J, Xie H, Ni J, Chen S, Zhao Q, Xie N, Lu L, Wang X,  RELA-induced MiR-21 Exerts Oncogenic Effects on PDAC via Targeting of ARHGAP24  J Cancer  2022  2022;13(9): 2781-2797 
    Mao Y, Hu B, Gong X, Luo S, Xia Y, Fu C,  Endoscopic extraction of a gastric submucosal foreign body after precise location with endoscopic ultrasound combined with endoscopic submucosal dissection  Endoscopy  2022  2022 Aug;54(8):E415-E416 
    Xie H, Xu J, Xie Z, Xie N, Lu J, Yu L,, Cheng L  Identification and validation of prognostic model for pancreatic ductal adenocarcinoma based on necroptosis-related genes  Front. Genet  2022  2022;13:919638 
    Zhao Q, Ren Y, Xie H, Yu L,  ELK3 mediated by ZEB1 facilitates the growth and metastasis of pancreatic carcinoma by activating the Wnt/β-catenin pathway  Frot Cell Dev Biol  2021  2021;9:700192 
    Guo L, Yu L, Zhao Q, Gong X, Xie H, Yuan G,, Wan X  Biodegradable JDBM coating stent has the potential to be used in the treatment of benign biliary strictures.  Biomed Mater  2021  2021;16(2) 
    Abdelfatah MM, Noll A, Kapil N, Shah R, Li L, Nustas R,, Luo H, Chen H, Xia L, Mekaroonkamol P, Shahnavaz N, Keilin S, Willingham F, Christie J, Cai Q  Long-term Outcome of Gastric Per-Oral Endoscopic Pyloromyotomy in Treatment of Gastroparesis  Clin Gastroenterol Hepatol  2021  2021, 19(4):816-824 
    Abdelfatah MM,, Kapil N, Noll A, Li L, Luo H, Chen H, Xia L, Chen X, Patel V, Mekaroonkamol P, Massaad J, Keilin S, Cai Q  Short-term Outcomes of Double Pyloromyotomy Versus Single Pyloromyotomy at Peroral Endoscopic Pyloromyotomy in Treatment of Gastroparesis (With Video)  Gastrointest Endosc.  2020  2020;92(3):603-609 
    , Dafan Chen and Xinjian Wan  Endoscopic purse-string suture technique: An effective remedy for a large iatrogenic rectal perforation  Dig Endosc  2019  e9-e10 
    Chen H,, Li L, Vachaparambil CT, Lamm V, Chu Y, Xu M, Cai Q  Current Status of Endoscopic Resection of Gastric Subepithelial Tumors  Am J Gastroenterol  2019  2019;114(5):718-725 
    Mekaroonkamol P, Patel V, Shah R,, Luo H, Shen S, Chen H, Shahnavaz N, Dacha S, Keilin S, Willingham FF, Christie J, Cai Q  Association between duration or etiology of gastroparesis and clinical response after gastric per-oral endoscopic pyloromyotomy.  Gastrointest Endosc  2019  89(5):969-976, 
    Chen H,, Li L, Vachaparambil CT, Lamm V, Chu Y, Xu M, Cai Q  Current Status of Endoscopic Resection of Gastric Subepithelial Tumors  Am J Gastroenterol  2019  114(5):718-725 
    Ren YC, Huang CL, Chen SM, Zhao QY, Wan XJ,  Dilation catheter-guided mini-forceps biopsy improves the diagnostic accuracy of malignant biliary strictures  Endoscopy.  2018  50(8): 809-812 
    Zhao Q, Luo H,  An unusual biliary "pearl".  Gastroenterology  2018  5085(18): 34610-9,  
    Wan X, Chen S, Zhao Q, Li T, Luo S, Cai X, Ren Y, Yu L,  The efficacy of temporary placement of nasobiliary drainage following endoscopic metal stenting to prevent post-ERCP cholangitis in patients with cholangiocarcinoma  Saudi J Gastroenterol  2018  2018 Jul 9. doi: 10.4103/sjg.SJG_94_18. 
    Fan H,Zheng L,Lai Y,Lu W,Yan Z,Xiao Q,,Tang M,Huang D,Wang Y,Li Z,Mei Y,Jiang Z,Liu X,Tang Q,Zuo D,Ye J,Yang Y,Huang H,Tang Z,Xiao J; China Irritable Bowel Syndrome Consortium  Tongxie Formula Reduces Symptoms of Irritable Bowel Syndrome.   Clin Gastroenterol Hepatol.  2017  15(11):1724-1732 
    Ren Y, Chen S, Cai X, Wan X,  Endoscopic ultrasonography-guided drainage combined with trans-duodenoscope cyclic irrigation technique for walled-off pancreatic necrosis  Dig Liver Dis  2017  49(1): 38-44 
    Zheng L,Lai Y,Lu W,,Fan H,Yan Z,Gong C,Wan X,Wu J,Huang D,Wang Y,Mei Y,Li Z,Jiang Z,Liu X,Ye J,Yang Y,Huang H,Xiao J.  Pinaverium Reduces Symptoms of Irritable Bowel Syndrome in a Multi- Center, Randomized Controlled Trial  Clin Gastroenterol Hepatol  2015  2015;13:1285–1292 
    ,Xiao J.  letter to the GGH  Clin Gastroenterol Hepatol  2015  2015 Jan  
    Cai XB,Zhang WX,Zhang RL,Dong Yuan X,Yang Q,Qi XS,,Qin Qian Y,Wang XP,Lu LG,Xu ZJ,Wan XJ.   Safety and efficacy of a novel plastic stent coated with stone-dissolving agents for the treatment of biliary stones in a porcine model.   Endoscopy,  2014  2014 Dec 5 
    Xu X,, Huang P, Wan X, Qin Y, Zhou L, Liu H, Bai H, Gao Y, Wang C, Meng X  Citrate induces apoptosis of the acute monocytic leukemia U937 cell line through regulation of HIF-1α signaling  Mol Med Rep  2013  2013; 8(5):1379-84 
    , Zheng P, Zhu Q, Lin J  Accurate preoperative staging of gastric cancer with combined endoscopic ultrasonography and PET-CT  Tohoku J.Exp.Med  2012  228(1): 9-16, 2012 
    Cao H, Zhu Q, Huang J,, Zhang S, Yao W, Zhang Y.   Regulation and functional role of eEF1A2 in pancreatic carcinoma  Biochem Biophys Res Commun,  2009  380(1): 11-6, 2009  
    , Ni P, Zhu Q, Cao H, Xu H, Zhang S, Chris Au, Zhang Y  Growth inhibitory effect of ternary complex factor Net on human pancreatic carcinoma cell lines.  Tohoku J.Exp.Med  2008  216(2):139-47, 2008