- 基本信息
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导师姓名：
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戴尅戎
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学科代码：
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100210
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性别：
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男
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学科名称：
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外科学
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培养单位：
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附属第九人民医院
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三级学科
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骨外
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导师类型：
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博士生导师
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专业领域名称：
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外科学 专业学位
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联系方式：
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021-63139920
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专业领域代码：
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105111
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邮编：
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200011
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邮箱地址：
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krdai@163.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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医用生物力学杂志主编
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中华创伤杂志英文版副总编辑
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临床骨科杂志主编
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上海交通大学荣誉讲席教授
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国家医管中心3D打印医学应用专家委员会顾问
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中华医学会数字医学分会终身名誉主任委员
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上海市增材制造协会名誉会长
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中国医疗器械行业协会3D打印医疗器械专委会会长
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- 科研项目
| 51631009 | 抗菌医用金属新材料的相关科学问题研究 | 国家自然科学基金 |
2017-01~2020-12
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142万元
| 子课题负责人 |
| 15411951100 | 老年人群糖皮质激素性骨质疏松骨折的防治新策略 | 上海市科委 |
2015-07~2018-09
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50万元
| 课题负责人 |
| 81190133 | 硬组织生物活性材料的宿主体内应答及其与宿主防御和再生体系的相互作用 | 国家自然科学基金重大项目 |
2012-01~2016-12
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350万元
| 课题负责人 |
| 11DJ1400303 | 镁合金降解产物的骨应答机制及安全性研究 | 上海市科委基础研究重大项目 |
2012-01~2014-12
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60万元
| 课题负责人 |
| XDA01030404 | 骨组织构建基础与临床应用 | 中国科学院战略性先导科技专项 |
2011-01~2015-12
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500万元
| 课题负责人 |
| 2006AA02Z344 | 国家重点基础研究计划（973） | 国家重点基础研究计划（973 |
2007-01~2010-01
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54.6万元
| 子课题负责人 |
- 学术论文
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Yiyun Wang, Jiajia Xu, Xudong Zhang, Chuandong Wang, Yan Huang,
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TNF-α-induced LRG1 promotes angiogenesis and mesenchymal stem cell migration in the subchondral bone during osteoarthritis
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CELL DEATH & DISEASE
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2017
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Mar 30;8(3):e2715
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Xudong Zhang, Chuandong Wang, Jingyu Zhao, Jiajia Xu, Yiyun Geng, Liming Dai, Yan Huang, Sai-Chuen Fu,
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miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2
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Cell Death and Disease
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2017
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8, e2734; doi:10.1038/cddis.2017.146
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Yuan Deng, Chuan Jiang, Cuidi Li, Tao Li, Mingzheng Peng, Jinwu Wang,
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3D printed scaffolds of calcium silicate-doped β-TCP synergize with co-cultured endothelial and stromal cells to promote vascularization and bone formation
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Scientific Reports
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2017
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Jul 17;7(1):5588
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Henghui Zhang, Yiping Wang, Songtao Ai, Xiaojun Chen, Liao Wang,
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Three-dimensional acetabular orientation measurement in a reliable coordinate system among one hundred Chinese.
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PLoS One
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2017
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Feb 16;12(2):e0172297.
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Yan Huang, Jing Wang, Fei Yang, Yingnan Shao, Xiaoling Zhang,
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Modification and evaluation of micro-nano structured porous bacterial cellulose scaffold for bone tissue engineering
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Mater Sci Eng C Mater Biol Appl
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2017
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Jun 1;75:1034-1041
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Li, Y; Liu, XQ; Tan, LL; Ren, L ; Wan, P; Hao, YQ; Qu, XH; Yang,, KR
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Enoxacin-loaded Poly (lactic-co-glycolic acid) Coating on Porous Magnesium Scaffold as a Drug Delivery System: Antibacterial Properties and Inhibition of Osteoclastic Bone Resorption
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2016
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32(9):865-873
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Wang YG, Qu XH, Yang Y, Han XG, Wang L, Qiao H, Fan QM, Tang TT,
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AMPK promotes osteogenesis and inhibits adipogenesis through AMPK-Gfi1-OPN axis.
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Cell Signal.
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2016
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Sep;28(9):1270-82
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Xin M, Qiao Z, Li J, Liu J, Song S, Zhao X, Miao P,Tang T, Wang L, Liu W, Yang X,, Huang G
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miR-22 inhibits tumor growth and metastasis by targeting ATP citrate lyase: evidence in osteosarcoma, prostate cancer, cervical cancer and lung cancer.
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Oncotarget.
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2016
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Jun 14. doi: 10.18632/oncotarget.10020. [Epub ahead of print]
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Li Y, Liu L, Wan P, Zhai Z, Mao Z, Ouyang Z, Yu D, Sun Q, Tan L, Ren L, Zhu Z, Hao Y1, Qu X, Yang K,
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Biodegradable Mg-Cu alloy implants with antibacterial activity for the treatment of osteomyelitis: In vitro and in vivo evaluations
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Biomaterials
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2016
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Nov;106:250-63
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He T, Chi G, Tian B, Tang T,
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Lentivirus transduced interleukin?1 receptor antagonist gene expression in murine bone marrow?derived mesenchymal stem cells in? vitro
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Mol Med Rep.
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2015
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Sep;12(3):4063-70
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Zhai Z, Qu X, Li H, Ouyang Z, Yan W, Liu G, Liu X, Fan Q, Tang T,
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Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by andrographolide via suppression of nuclear factor-κB-dependent matrix metalloproteinase-9 expression.
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Mol Med Rep.
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2015
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2015 Feb;11(2):1139-45.
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Ouyang Z, Zhai Z, Qin AN, Li H, Liu X, Qu X,
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Limitations of Gram staining for the diagnosis of infections following total hip or knee arthroplasty
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Exp Ther Med.
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2015
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2015 May;9(5):1857-1864.
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Zhai Z, Li H, Liu G, Qu X, Tian B, Yan W, Lin Z, Tang T, Qin A,
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Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo.
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Br J Pharmacol.
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2014
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2014 Feb;171(3):663-75
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Qu X, Zhang X, Zhai Z, Li H, Liu X, Li H, Liu G, Zhu Z, Hao Y,
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Association between physical activity and risk of fracture.
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J Bone Miner Res,
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2014
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2014 Jan;29(1):202-11
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Zhai Z, Qu X, Yan W, Li H, Liu G, Liu X, Tang T, Qin A,
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Andrographolide prevents human breast cancer-induced osteoclastic bone loss via attenuated RANKL signaling
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Breast Cancer Res Treat
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2014
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2014 Feb;144(1):33-45
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Zhai Z, Qu X,
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Reply to "Diagnostic value of a PCR-based technique for prosthetic joint infection"
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J Clin Microbiol
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2014
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2014 Jun;52(6):2283-4
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Ouyang Z, Zhai Z, Li H, Liu X, Qu X, Li X, Fan Q, Tang T, Qin A,
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Hypericin suppresses osteoclast formation and wear particle-induced osteolysis via modulating ERK signalling pathway
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Biochem Pharmacol.
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2014
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2014 Aug 1;90(3):276-87
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Li Y, Liu G, Zhai Z, Liu L, Li H, Yang K, Tan L, Wan P, Liu X, Ouyang Z, Yu Z, Tang T, Zhu Z, Qu X,
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Antibacterial properties of magnesium in an in vitro and in vivo model of implant-associated MRSA infection
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Antimicrob Agents Chemother.
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2014
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2014 Oct 6. pii: AAC.03936-14.
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Zhai Z, Qu X, Li H, Yang K, Wan P, Tan L, Ouyang Z, Liu X, Tian B, Xiao F, Wang W, Jiang C, Tang T, Fan Q, Qin A,
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The effect of metallic magnesium degradation products on osteoclast-induced osteolysis and attenuation of NF-κB and NFATc1 signaling
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Biomaterials
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2014
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2014 Aug;35(24):6299-310
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Liu X, Qu X, Wu C, Zhai Z, Tian B, Li H, Ouyang Z, Xu X, Wang W, Fan Q, Tang T, Qin A,
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The effect of enoxacin on osteoclastogenesis and reduction of titanium particle-induced osteolysis via suppression of JNK signaling pathway
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Biomaterials
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2014
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2014 Jul;35(22):5721-30
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Zhai Z, Li H, Qin A, Liu G, Liu X, Wu C, Li H, Zhu Z, Qu X,
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Meta-analysis of sonication fluid samples from prosthetic components for diagnosis of infection after total joint arthroplasty
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J Clin Microbiol
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2014
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2014 May;52(5):1730-6
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Sheng J, Qu X, Zhang X, Zhai Z, Li H, Liu X, Li H, Liu G, Zhu Z, Hao Y, Qin A,
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Coffee, tea, and the risk of hip fracture: a meta-analysis.
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Osteoporos Int
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2014
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2014 Jan;25(1):141-50
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Qu X, Zhai Z, Liu X, Li H, Ouyang Z, Wu C, Liu G, Fan Q, Tang T, Qin A,
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Dioscin inhibits osteoclast differentiation and bone resorption though down-regulating the Akt signaling cascades.
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Biochem Biophys Res Commun.
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2014
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2014 Jan 10;443(2):658-65.
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Han D,
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Prefabrication of a vascularized bone graft with Beta tricalcium phosphate using an in vivo bioreactor.
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Artif Organs
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2013
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2013;37-10:884-93.
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Xinhua Qu, Xiaolu Huang, Fangchun Jin, Hao Wang, Yongqiang Hao, Tingting Tang,
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Bone mineral density and all-cause, cardiovascular and stroke mortality: A
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International journal of cardiology
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2013
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2013;166:385-93.
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An BC, Wang Y, Jiang X, Lu HS, Fang ZY, Wang Y,
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Effects of Baduanjin (八段锦) exercise on knee osteoarthritis: A one-year study.
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Chin J Integr Med.
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2013
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2013 Feb;19(2):143-8
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Liu S, Jin F, Lin K, Lu J, Sun J, Chang J,, Fan C
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The effect of calcium silicate on in vitro physiochemical properties and in vivo osteogenesis, degradability and bioactivity of porous beta-tricalcium phosphate bioceramics
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Biomed Mater
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2013
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2013, 8(2):025008
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Qu X, Zhai Z, Wu C, Jin F, Li H, Wang L, Liu G, Liu X, Wang W, Li H, Zhang X, Zhu Z,
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Preoperative aspiration culture for preoperative diagnosis of infection in total hip or knee arthroplasty
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J Clin Microbiol
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2013
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2013;51-11:3830-4.
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Jin F, Qu X, Fan Q, Wang L, Tang T, Hao Y,
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Regulation of prostate cancer cell migration toward bone marrow stromal cell-conditioned medium by Wnt5a signaling.
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Mol Med Rep
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2013
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2013;8(5):1486-92.
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Jin F, Xie Y, Wang N, Qu X, Lu J, Hao Y,
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Poor osteoinductive potential of subcutaneous bone cement-induced membranes for tissue engineered bone.
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Connect Tissue Res
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2013
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2013;54-4-5:283-9.
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Li H, Zhai Z, Liu G, Tang T, Lin Z, Zheng M, Qin A,
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Sanguinarine inhibits osteoclast formation and bone resorption via suppressing RANKL-induced activation of NF-kappaB and ERK signaling pathways.
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Biochem Biophys Res Commun
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2013
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2013;430-3:951-6.
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Xinhua Qu, Fangchun Jin, Yongqiang Hao, Huiwu Li, Tingting Tang, Hao Wang, Weili Yan,
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Magnesium and the risk of cardiovascular events: A meta-analysis of prospective cohort studies
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Plos one,
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2013
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2013;8(3):e57720
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Ling-jie FU, Ting-ting TANG, Yong-qiang HAO,
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Long-term effects of alendronate on fracture healing and bone remodeling of femoral shaft in ovariectomized rats
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Acta Pharmacologica Sinica
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2013
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2013: 1–6
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FU Ling-jie,
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Simultaneous double dislocation of the interphalangeal joint in one finger
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Chin Med J
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2013
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2013;126 (5)974-975
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Chunming Ding, Zhiguang Qiao, Wenbo Jiang, Haowei Li, Jianhe Wei,
Guangdong Zhou*,
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Regeneration of a goat femoral head using a tissue-specific, biphasic
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Biomaterial
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2013
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2013 Sep;34(28):6706-16
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Qu X, Zhai Z, Li H, Li H, Liu X, Zhu Z, Wang Y, Liu G,
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PCR-based diagnosis of prosthetic joint infection.
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J Clin Microbiol
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2013
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2013;51-8:2742-6.
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Jiao Li, Ning Zhang, Xiaoju Huang, Jiake Xu, Julio C. Fernandes,, Xiaoling Zhang
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Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation.
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Cell Death Dis.
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2013
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2013 Oct 3;4:e832
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Qu X, Zhang X, Qin A, Liu G, Zhai Z, Hao Y, Li H, Zhu Z,
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Bone mineral density and risk of breast cancer in postmenopausal women
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Breast Cancer Res Treat.
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2013
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2013; 138(1): 261-71
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Qu X, Jin F, Hao Y, Zhu Z, Li H, Tang T,
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Nonlinear association between magnesium intake and the risk of colorectal cancer
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Eur J Gastroenterol Hepatol
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2013
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2013 Mar;25(3):309-18
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Qu X, Zhang X, Qin A, Liu G, Zhai Z, Hao Y, Li H, Zhu Z,
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Bone mineral density and risk of breast cancer in postmenopausal women
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Breast Cancer Res Treat.
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2013
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2013; 138(1): 261-71
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Cao L, Liu G, Gan Y, Fan Q, Yang F, Zhang X, Tang T,
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The use of autologous enriched bone marrow MSCs to enhance osteoporotic bone defect repair in long-term estrogen deficient goats
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Biomaterial
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2012
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Jul;33(20):5076-84. Epub 2012 Apr 13
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Jing Li, Jingang Huang, Liming Dai, Degang Yu, Qian Chen, Xiaoling Zhang,
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miR-146a, an IL-1b responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4
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Arthritis Research & Therapy
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2012
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Apr 16;14(2):R75
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Qin A, Cheng TS, Pavlos NJ, Lin Z,, Zheng MH
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V-ATPases in osteoclasts: Structure, function and potential inhibitors of bone resorption
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Int J Biochem Cell Biol.
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2012
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2012 Sep;44(9):1422-35. Epub 2012 May 29
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孙晓江,,谢幼专,汤亭亭,于志锋,张书红
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灌注型生物反应器中流速对人骨髓间充质干细胞增殖及成骨分化的影响
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医用生物力学
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2012
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2012,27(5):582~587
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Liao Wang, Robert T. Trousdale, Songtao Ai, Kai-Nan An,, and Bernard F. Morrey
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Dislocation After Total Hip Arthroplasty Among Patients With Developmental Dysplasia of the Hip
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The Journal of Arthroplasty
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2012
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May;27(5):764-9
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Xinhua Qu, Xiaolu Huang, Weili Yan, Lianming Wu,
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A meta-analysis of (18)FDG-PET–CT, (18)FDG-PET, MRI and bone scintigraphy for diagnosis of bone metastases in patients with lung cancer
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European Journal of Radiology
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2012
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May;81(5):1007-15
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Shi Y, Fu Y, Tong W, Geng Y, Lui PP, Tang T, Zhang X,
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Uniaxial mechanical tension promoted osteogenic differentiation of rat tendon-derived stem cells (rTDSCs) via the Wnt5a-RhoA pathway
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J Cell Biochem
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2012
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2012 Oct;113(10):3133-42
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Yan Huang, Xiaoling Zhang, Kewei Du, Fei Yang, Yu Shi, Jingang Huang, Tingting Tang, Di Chen,
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Inhibition of b-Catenin Signaling in Chondrocytes Induces Delayed Fracture Healing in Mice
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J Orthop Res
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2012
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Feb;30(2):304-10
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Qin A, Cheng TS, Lin Z, Cao L, Chim SM, Pavlos NJ, Xu J, Zheng MH,
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Prevention of wear particle-induced osteolysis by a novel V-ATPase inhibitor saliphenylhalamide through inhibition of osteoclast bone resorption
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PLoS One.
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2012
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2012;7(4):e34132. Epub 2012 Apr 11
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An Qin, Tak S. Cheng, Zhen Lin, Nathan J. Pavlos, Qing Jiang, Jiake Xu,, Ming H.Zheng*
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Versatile Roles of V-ATPases Accessory Subunit Ac45 inOsteoclast Formation
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PLoS ONE
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2011
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6(11): e27155
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Chunxi Yang, Chuan Gao, Yizao Wan, Tingting Tang, Shuhong Zhang,
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Preparation and Characterization of Three-Dimensional Nanostructured Macroporous Bacterial Cellulose/Agarose Scaffold for Tissue Engineering
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J Porous Mater
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2011
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18:545-552
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Shi Y, Li H, Zhang X, Fu Y, Huang Y, Lui PP, Tang T,
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Continuous cyclic mechanical tension inhibited Runx2 expression in mesenchymal stem cells through RhoA-ERK1/2 pathway
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J Cell Physiol
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2011
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226(8),2159-2169
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Xinhua Qu, Xiaolu Huang,
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Metal-on-metal or metal-on-polyethylene for total hip arthroplasty: a meta-analysis of prospective randomized studies
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Arch Orthop Trauma Surg
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2011
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Nov;131(11):1573-83
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Cao L, Yang F, Liu G, Yu D, Li H, Fan Q, Gan Y, Tang T,
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The promotion of cartilage defect repair using adenovirus mediated Sox9 gene transfer of rabbit bone marrow mesenchymal stem cells
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Biomaterials
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2011
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32(16) :3910 - 3920
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Jinwu Wang, Juliet Hou, Qi Li, Jian Tang, Biyu Rui, Shangchun Guo, Haitao Jiang, Cunyi Fan, You Wang, Zhenan Zhu,, Guang H Yue
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Establishment of an animal model of extra-vertebral foramen cervical nerve entrapment by local electrical stimulation and selection of suitable stimulation parameters
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NEURAL REGEN RES.
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2011
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.2011;6(29):2284-2289
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Fei Yang, WenWu, Lei Cao, Yan Huang, Zhenan Zhu, Tingting Tang,
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Pathways of macrophage apoptosis within the interface membrane in aseptic loosening of prostheses
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Biomaterials
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2011
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Dec;32(35):9159-9167
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Yang F, Xie Y, Li H, Tang T, Zhang X, Gan Y, Zheng X,
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Human bone marrow-derived stromal cells cultured with a plasma sprayed CaO-ZrO2-SiO2 coating
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J Biomed Mater Res B Appl Biomater
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2010
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Oct;95(1):192-201
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Yang C, Yuan G, Zhang J, Tang Z, Zhang X,
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Effects of magnesium alloys extracts on adult human bone marrow-derived stromal cell viability and osteogenic differentiation
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Biomed Mater
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2010
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Aug;5(4):045005. Epub 2010 Jun 23
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Yan MN,, Tang TT, Zhu ZA, Lou JR
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Reconstruction of peri-implant bone defects using impacted bone allograft and BMP-2 gene-modified bone marrow stromal cells
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J Biomed Mater Res A
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2010
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93A:304-313
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Mengning Yan,, Tingting Tang, Zhenan Zhu, Jue-ren Lou
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Reconstruction of peri-implant bone defects using impacted bone allograft and BMP-2 gene-modified bone marrow stromal cells
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J Biomed Mater Res
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2010
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93A:304-313
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Sun H,, Tang T, Zhang X
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Regulation of Osteoblast Differentiation by Slit2 in Osteoblastic Cells.
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Cells Tissues Organs
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2009
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190(2):69-80
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Yan Huang, Xiaogang Jin, Xiaoling, Zhang, Hongli Sun, Jinwen Tu, Tingting Tang, Jiang Chang,
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In vitro and in vivo evaluation of akermanite bioceramics for bone regeneration
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Biomaterials
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2009
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30(28):5041-8
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Wu W, Zhang X, Zhang C, Tang T, Ren W,
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Expansion of CD14(+)CD16 (+) peripheral monocytes among patients with aseptic loosening.
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Inflamm Res
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2009
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58(9):561-570
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Li D, Tang T, Lu J,
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Effects of flow shear stress and mass transport on the construction of a large-scale tissue-engineered bone in a perfusion bioreactor.
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Tissue Eng Part A
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2009
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15(10):2773-83
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Lingjie Fu, Tingting Tang, Yanying Miao, Yongqiang Hao,
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Effect of 1,25-dihydroxy vitamin D3 on fracture healing and bone remodeling in ovariectomized rat femora
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Bone
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2009
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(44):893-898
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Hou H, Zhang X, Tang T,, Ge R
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Enhancement of bone formation by genetically-engineered bone marrow stromal cells expressing BMP-2, VEGF and angiopoietin-1
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Biotechnol Lett
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2009
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31:1183-1189
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Zhang X, Tang T, Shi Q, Fernandes JC,
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The immunologic properties of undifferentiated and osteogenic differentiated mouse mesenchymal stem cells and its potential application in bone regeneration.
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Immunobiology
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2009
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214(3):179-86
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Fang B, Wan YZ, Tang TT, Gao C,
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Proliferation and Osteoblastic Differentiation of Human Bone Marrow Stromal Cells on Hydroxyapatite/Bacterial Cellulose Nanocomposite Scaffolds.
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Tissue Eng Part A
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2009
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15(5):1091-8
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ZhiHu Qu, Huajie Wang, Tingting Tang, XiaoLing Zhang, JinYe Wang,
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Evaluation of the zein/inorganics composite on biocompatibility and osteoblastic differentiation.
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Acta Biomater
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2008
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4(5):1360-8
|
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富灵杰, 汤亭亭,
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骨质疏松性骨折用药选择的研究进展
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中华老年医学杂志
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2008
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27(10):793-795
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Chao Zhang, Tingting Tang, Weiping Ren, Xiaoling Zhang,
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Influence of mouse genetic background on wear particle-induced
in vivo inflammatory osteolysis
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Inflamm Res
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2008
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57(5):211-5
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Deqiang.Li,, Tingting Tang
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Effects of dextran on proliferation and osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells
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Informa cytortherapy
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2008
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10(6):587-596
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Yaokai Gan,, Pu Zhang, Tingting Tang, Zhenan Zhu, Jianxi Lu
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The clinical use of enriched bone marrow stem cells combined with porous beta-tricalcium phosphate in posterior spinal fusion
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Biomaterials
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2008
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29(29):3973-3982
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Dong yun Gu, Yazhu Chen,, Su Zhang, Jianbin Yuan
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Ectopic Osteogenesis by Ex Vivo Gene Therapy Using Beta
Tricalcium Phosphate as a Carrier
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Connective Tissue Research
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2008
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49:343–350
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XiaoJiang Sun, Yaokai Gan, Tingting Tang, Xiaoling Xhang,
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Immunomodulatory and osteogenic differentiation effects of mesenchymal stem cells by adenovirus-mediated coexpression of CTLA4Ig and BMP2
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Tissue Engineering
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2008
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14(3):391-400
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ZhiHu Qu, XiaoLing Zhang, Tingting Tang,
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Promotion of osteogenesis through β-catenin signaling by desferrioxamine
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BBRC
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2008
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370(2):332-7.
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Yaokai Gan,, Pu Zhang, Tingting Tang, Zhenan Zhu, Jianxi Lu
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The clinical use of enriched bone marrow stem cells combined with porous beta-tricalcium phosphate in posterior spinal fusion
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Biomaterials
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2008
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29(29):3973-3982
|
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Xiaoling Zhang, Chao Zhang, Tingting, Zhihu Qu, Jueren Lou,
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Immunomodulatory and osteogenic differentiation effects of mesenchymal stem cells by adenovirus-mediated coexpression of CTLA4Ig and BMP2
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Journal of Orthopedic Research
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2008
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26(3):314-21
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Lingjie Fu, Tingting Tang, Yanying Miao, Shuhong Zhang, Zhihu Qu,
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Stimulation of osteogenic differentiation and inhibition of adipogenic differentiation in bone marrow stromal cells by alendronate via ERK and JNK activation
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Bone
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2008
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43(1):40–47
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