- 基本信息
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导师姓名：
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段俊丽
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学科代码：
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100201
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性别：
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女
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学科名称：
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内科学
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培养单位：
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附属新华医院
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三级学科
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心血管病
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导师类型：
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博士生导师
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专业领域名称：
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内科学 专业学位
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联系方式：
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duanjunli@xinhuamed.com.cn
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专业领域代码：
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105101
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邮编：
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200092
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邮箱地址：
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junlishanghai2005@yahoo.com.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中国老年学和老年医学学会智慧医疗与大健康分会 委员
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中国老年医学研究机构联盟 委员
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上海市高血压学会 委员
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中华医学会老年医学分会老年基础医学专业学组 委员
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中国中西医结合学会 虚症与老年医学专业委员会转化医学学组 组长
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中国老年医学学会基础与转化医学分会 委员
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中国老年保健医学研究会女性健康分会 副主任委员
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中华医学会中西医高血压学会 委员
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中华医学会老年医学分会基础学组 委员
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- 科研项目
| 12074253 | 超声相控阵声动力精准定位与靶向血管治疗机理和方法研究 | 国家自然科学基金
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2021-01~2024-12
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62万元
| 课题负责人 |
| YG2019ZDA21 | 超声相控阵智能模拟针刺手法系统 | 上海交通大学“交大之星”计划医工交叉研究基金 |
2020-01~2022-12
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100万元
| 课题负责人 |
| 18401900500 | 超声相控阵模拟针刺手法对脑梗死后遗症肢体活动障碍改善的疗效研究 | 上海市科学技术委员会医学引导类（中、西医）科技支撑项目 |
2018-09~2021-09
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25万元
| 课题负责人 |
| 11774232 | “健康样”血管新生的超声干预与光声评估方法研究 | 国家自然科学基金面上项目 |
2018-01~2021-12
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65万元
| 课题负责人 |
| 11574210 | 利用光谱移动效应对动脉硬化早期诊断的研究 | 国家自然科学基金 |
2016-01~2019-10
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75万元
| 课题负责人 |
| 15LC18 | 低强度连续超声波辅助治疗下肢动脉硬化闭塞症的临床研究 | 院基金 |
2016-01~2018-01
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6万元
| 课题负责人 |
| 11374213 | 单细胞内药物分布的扫描探针研究 | 国家自然科学基金 |
2014-01~2017-12
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90万元
| 课题负责人 |
| 11nm0503600 | 磷酸钙纳米载体负载Ang-VEGF双基因用于治疗性血管新生研究 | 上海市科学技术委员会科研计划项目纳米专项资助 |
2011-10~2014-09
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60万元
| 课题负责人 |
| 09JC1411100 | 计算机辅助血压、血糖动态特性与心血管疾病关联性的研究 | 上海市科委"创新行动计划"基础研究重点项目 |
2009-09~2011-08
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30万元
| 课题负责人 |
| | 胆碱能抗炎机制在限制热量摄入延缓脑梗死发生中的作用研究 | 上海交通大学医工合作专项 |
2009-06~2011-05
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5万元
| 课题负责人 |
| 2009CB521900 | 脑血管疾病发生和防治的基础研究 | 973项目课题中承担其中一部分 |
2009-01~2014-12
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60万元
| 主要责任人 |
| 08ZR1411200 | 凝聚态物理学方法对血压波动在老年血管损伤现象的研究 | 上海市科委，自然科学基金 |
~2010-09
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10万元
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- 学术论文
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Yang SW, Xuelian Wang XL, He P, Xu AL, Wang G,, Shi YQ, Ding GQ.
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Graphene Quantum Dots with Pyrrole N and Pyridine N: Superior Reactive Oxygen Species Generation Efficiency for Metal-Free Sonodynamic Tumor The17(10)
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Small.
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2021
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17(10)
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Huang GJ, Yu HP, Wang XL,Ning BB, Gao J, Shi YQ, Zhu YJ,
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Highly porous and elastic aerogel based on ultralong hydroxyapatite nanowires for high-performance bone regeneration and neovascularization.
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J. Mater. Chem. B, 2021,
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2021
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9, 1277-87.
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Xue-Lian Wang, Jia Qi1, Yi-Qin Shi, Zhao-Yang Lu, Rui-Lin Li, Gao-Jian Huang, Bing-Bing Ning,
Liang-Shi Hao, Huan Wang, Chang-Ning Hao, Yue Li, Hong-Sheng Zhou,
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Atorvastatin plus therapeutic ultrasound improve postnatal neovascularization in response to hindlimb ischemia via the PI3K-Akt pathway
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Am J Transl Res
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2019
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11(5):2877-2886
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Zhi-Xiao Su,Yi-Qin Shi,Zhao-Yang Lu, Rui-Lin Li, Xue-Lian Wang, Bing-Bing Ning,, Liang-Shi Hao, Jun-Hui Duan, Yue Li, Ying-Jie Zhu, Chang-Ning Hao, Rui Wang
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Comparative study of nanostructured carriers of calcium phosphate and magnesium phosphate loaded with SRT1720 for the protection of H2O2-induced senescent endothelium.
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Am J Transl Res
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2018
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10(7): 2068–2077
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Jia Qi, Feng Wang, Ping Yang,Xuelian Wang, Renjie Xu, Jihui Chen, Yanggang Yuan, Zhaoyang Lu,
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Mitochondrial Fission Is Required for Angiotensin II-Induced Cardiomyocyte Apoptosis Mediated by a Sirt1-p53 Signaling Pathway
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Front Pharmacol.
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2018
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9:176
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Lu ZY, Zhou HS, Su ZX, Qi J, Zhang J, Xue GH, Li Y, Hao CN, Shi YQ ,
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Therapeutic ultrasound plus pulsed electromagnetic field improves recovery from peripheral arterial disease in hypertension.
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Am J Transl Res
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2017
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9: 4184-4194
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An Hu,Jing-Juan Huang,Jing-Fei Zhang,Wei-Jun Dai, Rui-Lin Li,Zhao-Yang Lu,,Ji-Ping Li, Xiao-Ping Chen,Jing-Ping Fan,Wei-Hua Xu,Hong-Liang Zheng
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Curcumin induces G2/M cell cycle arrest and apoptosis of head and neck squamous cell carcinoma in vitro and in vivo through ATM/Chk2/p53-dependent pathway
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Oncotarget
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2017
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8:50747-50760
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Huang JJ, Shi YQ, Li RL, Hu A, Lu ZY, Weng L, Han YP, Wang SQ, Zhang L, Hao CN ,
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Therapeutic ultrasound protects HUVECs from ischemia/hypoxia-induced apoptosis via the PI3K-Akt pathway.
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Am J Transl Res
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2017
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9: 1990-1999
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Qi J,Wang JJ,, Lu ZY, Yuan YG
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Leonurine Improves Age-Dependent Impaired Angiogenesis: Possible Involvement of Mitochondrial Function and HIF-1α Dependent VEGF Activation
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Front Pharmacol.
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2017
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:284
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Lu ZY, Li RL, Zhou HS, Huang JJ, Qi J, Su ZX, Zhang L, Li Y, Shi YQ, Hao CN,
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Rescue of hypertension-related impairment of angiogenesis by therapeutic ultrasound
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Am J Transl Res
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2016
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8(7):3087-3096
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Li RL, Lu ZY,Huang JJ, Qi J, Hu A, Su ZX, Zhang L, Shi YQ, Hao CN,
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SRT1720, a SIRT1 specific activator, protected H2O2-induced senescent endothelium
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Am J Transl Res
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2016
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8(7):2876-2888
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An Hu, Jing-Juan Huang, Rui-Lin Li, Zhao-Yang Lu,, Wei-Hua Xu,Xiao-Ping Chen,Jing-Ping Fan
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Curcumin as therapeutics for the treatment of head and neck squamous cell carcinoma by activating SIRT1
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Sci Rep
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2015
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5:13429. doi: 10.1038/srep13429
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An Hu, Jing-Juan Huang, Wei-Hua Xu, Xiao-Jie Jin, Ji-Ping Li, Yuan-Jia Tang, Xin-Fang Huang, Hui-Juan
Cui, Guang-Bin Sun, Rui-Lin Li,
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MiR-21/miR-375 ratio is an independent prognostic factor in patients with laryngeal squamous cell carcinoma
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Am J Cancer Res
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2015
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5(5):1775-1785
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Wei-Ming Wang, Zhao Liu,Ai-Jun Liu,Yu-Xiang Wang,Hong-Gang Wang, Di An,Bin Heng,Lai-Hua Xie,,Yan-Qiang Liu
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The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation
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CNS Neuroscience & Therapeutics
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2015
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21(9):708-717
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Li YING, Gang LI, Si-si WEI, Hong WANG1, An PEI, Xun WANG, Kai GUO, Xian-jin LUO, Ji-min GAO, Qing ZHOU, Wei
LI, Ying YU, Yi-gang LI,, Yue-peng WANG
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Sanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation
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Acta Pharmacologica Sinica
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2015
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36(2):229-240
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Jing-Juan Huang, Yi-Qin Shi, Rui-Lin Li, An Hu, Zhao-Yang Lu, Liang Weng, Shen-Qi Wang, Yi-Peng Han, Lan Zhang, Bao Li, Chang-Ning Hao,
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Angiogenesis effect of therapeutic ultrasound on HUVECs through activation of the PI3K-Akt-eNOS signal pathway
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Am J Transl Res
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2015
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7(6):1106-1115
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Rui-Lin Li, Jing-Juan Huang, Yi-Qin Shi, An Hu, Zhao-Yang Lu, Liang Weng, Shen-Qi Wang, Yi-Peng Han, Lan Zhang, Chang-Ning Hao,
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Pulsed electromagnetic field improves postnatal neovascularization in response to hindlimb ischemia
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Am J Transl Res
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2015
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7(3):430-444
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Huang ZY, Xiong DY, Zhang GX, Shi YQ, Hao CN,
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Nonnegative Matrix Factorization Numerical Method for Integrated Photonic Cavity Based Spectroscopy
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Hindawi Publishing Corporation Journal of Nanomaterials
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2014
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310601, 1-5
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Hao CN, Huang ZH, Song SW, Shi YQ, Cheng XW , Lu W, Su DF,
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Arterial Baroreflex Dysfunction Impairs Angiogenesis: A Murine Model of Hindlimb Ischemia
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J Am Heart Assoc.
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2014
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3:e000804 doi: 10.1161
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Chao Qi,Jing-Juan Huang,Feng Chen,Jin Wu, Chang-Ning Hao, Yi-Qin Shi,,Ying-Jie Zhu
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Synthesis, characterization and applications of calcium carbonate/fructose 1,6-bisphosphate composite nanospheres and carbonated hydroxyapatite porous nanospheres
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J. Mater. Chem. B
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2014
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2(47). DOI: 10.1039/C4TB01342E
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Hao CN, Huang JJ, Shi YQ, Li HY, Guo XG, Cheng XW,Li RL, Lu W, Zhu YZ,
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Pulsed Electromagnetic Field Improves Cardiac Function in Response to Myocardial Infarction
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Am J Transl Res
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2014
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6(3):281-290
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Jing-Juan Huang,Yi-Qin Shi, Rui-Lin Li, An Hu, Hong-Sheng Zhou, Qian Cheng, Zheng Xu, Zhi-Ming
Yang, Chang-Ning Hao,
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Angiogenesis effect of therapeutic ultrasound on ischemic hind limb in mice
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Am J Transl Res
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2014
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6(6):703-713
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Guo JM, Liu AJ, Zang P, Dong WZ, Ying L, Wang W, Xu P, Song XR, Cai J, Zhang SQ,, Mehta JL, Su DF
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ALDH2 protects against stroke by clearing 4-HNE
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Cell Res
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2013
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23:915-30
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Sun Y, Gui H, Li Q, Luo ZM, Zheng MJ,, Liu X
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MicroRNA-124 protects neurons against apoptosis in cerebral ischemic stroke
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CNS Neurosci Ther
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2013
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19 :813-9.
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Huang ZH, Guo W, Zhang LL, Song SW, Hao CN,
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Donepezil Protect Endothelial Cells against Hydrogen Peroxide Induced Cell Injury
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CNS Neuroscience & Therapeutics
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2012
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18:185-7
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Hao CN, Geng YJ, Li F, Yang T, Su DF,,Li Y
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Insulin-like growth factor-1 receptor activation prevents hydrogen peroxide-induced oxidative stress, mitochondrial dysfunction and apoptosis. Apoptosis
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Apoptosis
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2011
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16: 1118-27
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Ma K, Liu Y, Zhu Q, Liu CH,,Tan BK, Zhu YZ
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H2S Donor, S-Propargyl-Cysteine, Increases CSE in SGC-7901 and Cancer-Induced Mice: Evidence for a Novel Anti-Cancer Effect of Endogenous H2S?
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PLoS One
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2011
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6:1-7
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Hao CN, Huang ZH, Shi YQ, Lu W,
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A New Index to Predict the Incidence of Cerebral Infarction
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CNS Neuroscience & Therapeutics.
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2011
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17:783-4
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Huang ZH, Hao CN, Zhang LL, Huang YC, Shi YQ, Jiang GR,
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Non-invasive blood glucose sensing on human body with near-infrared reflection spectroscopy
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Interational Symposium on Photoelectronic Detection and Imaging
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2011
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8193: 1-10
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Song SW, Liu AJ, Bai B, Ma XJ, Shen FM,,Su DF
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Blood pressure reduction combining baroreflex restoration for stroke prevention in hypertension in rats
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Original Research Article
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2010
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30:1–7
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,Hao CN, Lu W, Han L, Pan ZH, Gu Y, Liu BJ, Tao R, Shi YQ, Du YY
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A new method for assessing variability of 24-h blood pressure and its first application in 1526 elder men
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Clin Exp Pharmacol Physiol
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2009
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36: 1093–1098
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Li L, Zhao L, Yi-Ming W, Yu YS, Xia CY,, Su DF
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Sirt1 hyperexpression in SHR heart related to left ventricular hypertrophy
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Can J Physiol Pharmacol
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2009
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87: 56-62
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Li DJ, Tang Q, Shen FM, Su DF,, X Tao
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Overexpressed α7 nicotinic acetylcholine receptor inhibited proinflammatory cytokine release in NIH3T3 cells
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Journal of Bioscience and Bioengineering
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2009
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108（2）: 85–91
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Sasaki K,,Murohara T, Ikeda H, Shintani S, Shimada T, Akita T, K Egami, Imaizumi T
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Rescue of hyercholesterolemia-related impairment of angiogenesis by oral folate supplementation
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J Am Coll Cardiol
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2003
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42(2):364-372
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Shintani S, Murohara T, Ikeda H, Ueno T,, Imaizumi T
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Augmentation of postnatal neovascularization with autologous bone marrow transplantation
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Circulation
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2001
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103: 897-903
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, Murohara T, Ikeda H, Kotoh A, Kawada H, Yamamoto N, Ueno T, Imaizumi T
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Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: Nitric oxide-dependent mechanism.
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circulation
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2000
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102:370-6
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, Murohara T, Ikeda H, Kotoh A, Kawada H, Yamamoto N, Ueno T, Imaizumi T
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Hyperhomocysteinemia impairs angiogenesis and collateral vessel formation in response to hindlimb ischemia
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Arterioscler Thromb Vasc Biol.
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2000
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20:2579-85
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Murohara T, Ikeda H,,Shintani S, Sasaki K, Eguchi H, Onitsuka I, Matsui K, Imaizumi T
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Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization
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J. clin. Invest
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1999
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105: 1527-36
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