• 基本信息
    导师姓名: 段俊丽 专业代码: 100201
    性别: 专业名称: 内科学
    培养单位: 附属新华医院 三级学科/
    专业领域:
    心血管病
    导师类型: 博士生导师 专业学位导师:
    联系方式:
    邮编: 邮箱地址: junlishanghai2005@yahoo.com.cn
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    中华医学会中西医分会高血压学会委员
    中华医学会老年医学分会基础学组委员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    YG2019ZDA21超声相控阵智能模拟针刺手法系统上海交通大学“交大之星”计划医工交叉研究基金 2020-01~2022-12 100万元  课题负责人
    18401900500超声相控阵模拟针刺手法对脑梗死后遗症肢体活动障碍改善的疗效研究上海市科学技术委员会医学引导类(中、西医)科技支撑项目 2018-09~2021-09 25万元  课题负责人
    11774232“健康样”血管新生的超声干预与光声评估方法研究国家自然科学基金面上项目 2018-01~2021-12 65万元  课题负责人
    11574210利用光谱移动效应对动脉硬化早期诊断的研究国家自然科学基金 2016-01~2019-10 75万元  课题负责人
    15LC18 低强度连续超声波辅助治疗下肢动脉硬化闭塞症的临床研究院基金 2016-01~2018-01 6万元  课题负责人
    11374213单细胞内药物分布的扫描探针研究国家自然科学基金 2014-01~2017-12 90万元  课题负责人
    11nm0503600磷酸钙纳米载体负载Ang-VEGF双基因用于治疗性血管新生研究上海市科学技术委员会科研计划项目纳米专项资助 2011-10~2014-09 60万元  课题负责人
    09JC1411100计算机辅助血压、血糖动态特性与心血管疾病关联性的研究上海市科委"创新行动计划"基础研究重点项目 2009-09~2011-08 30万元  课题负责人
     胆碱能抗炎机制在限制热量摄入延缓脑梗死发生中的作用研究上海交通大学医工合作专项 2009-06~2011-05 5万元  课题负责人
    2009CB521900脑血管疾病发生和防治的基础研究973项目课题中承担其中一部分 2009-01~2014-12 60万元  主要责任人
    08ZR1411200凝聚态物理学方法对血压波动在老年血管损伤现象的研究上海市科委,自然科学基金 ~2010-09 10万元   
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Xue-Lian Wang, Jia Qi1, Yi-Qin Shi, Zhao-Yang Lu, Rui-Lin Li, Gao-Jian Huang, Bing-Bing Ning, Liang-Shi Hao, Huan Wang, Chang-Ning Hao, Yue Li, Hong-Sheng Zhou,  Atorvastatin plus therapeutic ultrasound improve postnatal neovascularization in response to hindlimb ischemia via the PI3K-Akt pathway  Am J Transl Res   2019  11(5):2877-2886 
    Zhi-Xiao Su,Yi-Qin Shi,Zhao-Yang Lu, Rui-Lin Li, Xue-Lian Wang, Bing-Bing Ning,, Liang-Shi Hao, Jun-Hui Duan, Yue Li, Ying-Jie Zhu, Chang-Ning Hao, Rui Wang  Comparative study of nanostructured carriers of calcium phosphate and magnesium phosphate loaded with SRT1720 for the protection of H2O2-induced senescent endothelium.  Am J Transl Res  2018  10(7): 2068–2077 
    Jia Qi, Feng Wang, Ping Yang,Xuelian Wang, Renjie Xu, Jihui Chen, Yanggang Yuan, Zhaoyang Lu,  Mitochondrial Fission Is Required for Angiotensin II-Induced Cardiomyocyte Apoptosis Mediated by a Sirt1-p53 Signaling Pathway  Front Pharmacol.   2018  9:176 
    Lu ZY, Zhou HS, Su ZX, Qi J, Zhang J, Xue GH, Li Y, Hao CN, Shi YQ ,  Therapeutic ultrasound plus pulsed electromagnetic field improves recovery from peripheral arterial disease in hypertension.  Am J Transl Res  2017  9: 4184-4194 
    An Hu,Jing-Juan Huang,Jing-Fei Zhang,Wei-Jun Dai, Rui-Lin Li,Zhao-Yang Lu,,Ji-Ping Li, Xiao-Ping Chen,Jing-Ping Fan,Wei-Hua Xu,Hong-Liang Zheng  Curcumin induces G2/M cell cycle arrest and apoptosis of head and neck squamous cell carcinoma in vitro and in vivo through ATM/Chk2/p53-dependent pathway  Oncotarget  2017  8:50747-50760 
    Huang JJ, Shi YQ, Li RL, Hu A, Lu ZY, Weng L, Han YP, Wang SQ, Zhang L, Hao CN ,  Therapeutic ultrasound protects HUVECs from ischemia/hypoxia-induced apoptosis via the PI3K-Akt pathway.   Am J Transl Res  2017  9: 1990-1999 
    Qi J,Wang JJ,, Lu ZY, Yuan YG  Leonurine Improves Age-Dependent Impaired Angiogenesis: Possible Involvement of Mitochondrial Function and HIF-1α Dependent VEGF Activation  Front Pharmacol.  2017  :284 
    Lu ZY, Li RL, Zhou HS, Huang JJ, Qi J, Su ZX, Zhang L, Li Y, Shi YQ, Hao CN,  Rescue of hypertension-related impairment of angiogenesis by therapeutic ultrasound  Am J Transl Res   2016  8(7):3087-3096 
    Li RL, Lu ZY,Huang JJ, Qi J, Hu A, Su ZX, Zhang L, Shi YQ, Hao CN,  SRT1720, a SIRT1 specific activator, protected H2O2-induced senescent endothelium  Am J Transl Res   2016  8(7):2876-2888 
    An Hu, Jing-Juan Huang, Rui-Lin Li, Zhao-Yang Lu,, Wei-Hua Xu,Xiao-Ping Chen,Jing-Ping Fan  Curcumin as therapeutics for the treatment of head and neck squamous cell carcinoma by activating SIRT1  Sci Rep  2015  5:13429. doi: 10.1038/srep13429 
    An Hu, Jing-Juan Huang, Wei-Hua Xu, Xiao-Jie Jin, Ji-Ping Li, Yuan-Jia Tang, Xin-Fang Huang, Hui-Juan Cui, Guang-Bin Sun, Rui-Lin Li,  MiR-21/miR-375 ratio is an independent prognostic factor in patients with laryngeal squamous cell carcinoma  Am J Cancer Res  2015  5(5):1775-1785 
    Wei-Ming Wang, Zhao Liu,Ai-Jun Liu,Yu-Xiang Wang,Hong-Gang Wang, Di An,Bin Heng,Lai-Hua Xie,,Yan-Qiang Liu  The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation  CNS Neuroscience & Therapeutics  2015  21(9):708-717 
    Li YING, Gang LI, Si-si WEI, Hong WANG1, An PEI, Xun WANG, Kai GUO, Xian-jin LUO, Ji-min GAO, Qing ZHOU, Wei LI, Ying YU, Yi-gang LI,, Yue-peng WANG  Sanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation  Acta Pharmacologica Sinica  2015  36(2):229-240 
    Jing-Juan Huang, Yi-Qin Shi, Rui-Lin Li, An Hu, Zhao-Yang Lu, Liang Weng, Shen-Qi Wang, Yi-Peng Han, Lan Zhang, Bao Li, Chang-Ning Hao,  Angiogenesis effect of therapeutic ultrasound on HUVECs through activation of the PI3K-Akt-eNOS signal pathway  Am J Transl Res  2015  7(6):1106-1115 
    Rui-Lin Li, Jing-Juan Huang, Yi-Qin Shi, An Hu, Zhao-Yang Lu, Liang Weng, Shen-Qi Wang, Yi-Peng Han, Lan Zhang, Chang-Ning Hao,  Pulsed electromagnetic field improves postnatal neovascularization in response to hindlimb ischemia  Am J Transl Res  2015  7(3):430-444 
    Huang ZY, Xiong DY, Zhang GX, Shi YQ, Hao CN,  Nonnegative Matrix Factorization Numerical Method for Integrated Photonic Cavity Based Spectroscopy  Hindawi Publishing Corporation Journal of Nanomaterials  2014  310601, 1-5 
    Hao CN, Huang ZH, Song SW, Shi YQ, Cheng XW , Lu W, Su DF,  Arterial Baroreflex Dysfunction Impairs Angiogenesis: A Murine Model of Hindlimb Ischemia  J Am Heart Assoc.  2014  3:e000804 doi: 10.1161 
    Chao Qi,Jing-Juan Huang,Feng Chen,Jin Wu, Chang-Ning Hao, Yi-Qin Shi,,Ying-Jie Zhu  Synthesis, characterization and applications of calcium carbonate/fructose 1,6-bisphosphate composite nanospheres and carbonated hydroxyapatite porous nanospheres  J. Mater. Chem. B  2014  2(47). DOI: 10.1039/C4TB01342E 
    Hao CN, Huang JJ, Shi YQ, Li HY, Guo XG, Cheng XW,Li RL, Lu W, Zhu YZ,  Pulsed Electromagnetic Field Improves Cardiac Function in Response to Myocardial Infarction  Am J Transl Res  2014  6(3):281-290 
    Jing-Juan Huang,Yi-Qin Shi, Rui-Lin Li, An Hu, Hong-Sheng Zhou, Qian Cheng, Zheng Xu, Zhi-Ming Yang, Chang-Ning Hao,  Angiogenesis effect of therapeutic ultrasound on ischemic hind limb in mice  Am J Transl Res  2014  6(6):703-713 
    Guo JM, Liu AJ, Zang P, Dong WZ, Ying L, Wang W, Xu P, Song XR, Cai J, Zhang SQ,, Mehta JL, Su DF  ALDH2 protects against stroke by clearing 4-HNE  Cell Res  2013  23:915-30 
    Sun Y, Gui H, Li Q, Luo ZM, Zheng MJ,, Liu X  MicroRNA-124 protects neurons against apoptosis in cerebral ischemic stroke  CNS Neurosci Ther  2013  19 :813-9. 
    Huang ZH, Guo W, Zhang LL, Song SW, Hao CN,  Donepezil Protect Endothelial Cells against Hydrogen Peroxide Induced Cell Injury  CNS Neuroscience & Therapeutics  2012  18:185-7 
    Hao CN, Geng YJ, Li F, Yang T, Su DF,,Li Y  Insulin-like growth factor-1 receptor activation prevents hydrogen peroxide-induced oxidative stress, mitochondrial dysfunction and apoptosis. Apoptosis  Apoptosis  2011  16: 1118-27 
    Ma K, Liu Y, Zhu Q, Liu CH,,Tan BK, Zhu YZ  H2S Donor, S-Propargyl-Cysteine, Increases CSE in SGC-7901 and Cancer-Induced Mice: Evidence for a Novel Anti-Cancer Effect of Endogenous H2S?  PLoS One  2011  6:1-7 
    Hao CN, Huang ZH, Shi YQ, Lu W,  A New Index to Predict the Incidence of Cerebral Infarction  CNS Neuroscience & Therapeutics.  2011  17:783-4 
    Huang ZH, Hao CN, Zhang LL, Huang YC, Shi YQ, Jiang GR,  Non-invasive blood glucose sensing on human body with near-infrared reflection spectroscopy  Interational Symposium on Photoelectronic Detection and Imaging  2011  8193: 1-10 
    Song SW, Liu AJ, Bai B, Ma XJ, Shen FM,,Su DF  Blood pressure reduction combining baroreflex restoration for stroke prevention in hypertension in rats  Original Research Article  2010  30:1–7 
    ,Hao CN, Lu W, Han L, Pan ZH, Gu Y, Liu BJ, Tao R, Shi YQ, Du YY   A new method for assessing variability of 24-h blood pressure and its first application in 1526 elder men  Clin Exp Pharmacol Physiol  2009  36: 1093–1098 
    Li L, Zhao L, Yi-Ming W, Yu YS, Xia CY,, Su DF  Sirt1 hyperexpression in SHR heart related to left ventricular hypertrophy  Can J Physiol Pharmacol  2009  87: 56-62 
    Li DJ, Tang Q, Shen FM, Su DF,, X Tao  Overexpressed α7 nicotinic acetylcholine receptor inhibited proinflammatory cytokine release in NIH3T3 cells  Journal of Bioscience and Bioengineering  2009  108(2): 85–91 
    Sasaki K,,Murohara T, Ikeda H, Shintani S, Shimada T, Akita T, K Egami, Imaizumi T  Rescue of hyercholesterolemia-related impairment of angiogenesis by oral folate supplementation   J Am Coll Cardiol  2003  42(2):364-372 
    Shintani S, Murohara T, Ikeda H, Ueno T,, Imaizumi T  Augmentation of postnatal neovascularization with autologous bone marrow transplantation  Circulation  2001  103: 897-903 
    , Murohara T, Ikeda H, Kotoh A, Kawada H, Yamamoto N, Ueno T, Imaizumi T  Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: Nitric oxide-dependent mechanism.   circulation  2000  102:370-6 
    , Murohara T, Ikeda H, Kotoh A, Kawada H, Yamamoto N, Ueno T, Imaizumi T  Hyperhomocysteinemia impairs angiogenesis and collateral vessel formation in response to hindlimb ischemia  Arterioscler Thromb Vasc Biol.  2000  20:2579-85 
    Murohara T, Ikeda H,,Shintani S, Sasaki K, Eguchi H, Onitsuka I, Matsui K, Imaizumi T  Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization  J. clin. Invest  1999  105: 1527-36