- 基本信息
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导师姓名：
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陈冰
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学科代码：
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100700
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性别：
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男
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学科名称：
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药学
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培养单位：
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附属瑞金医院
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三级学科
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导师类型：
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硕士生导师
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专业领域名称：
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药学硕士 专业学位
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联系方式：
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上海交通大学医学院附属瑞金医院药剂科
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专业领域代码：
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105500
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邮编：
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200025
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邮箱地址：
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chchenbing@hotmail.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中国药理学会定量药理专业委员会委员
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上海药理学会临床药理专业委员会委员
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中国药理学会治疗药物监测研究专业委员会委员
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上海药理学会药物代谢专业委员会委员
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《中国医院药学杂志》通讯编委
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- 科研项目
| 81973387 | 肾移植患者钙调磷酸酶抑制剂在外周血淋巴细胞中药动与药效个体变异 | 国家自然科学基金 |
2020-01~2023-12
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54万元
| 课题负责人 |
| 81473275 | 霉酚酸对中国肝移植患者IMPDH与淋巴细胞活化影响的个体差异机制研究 | 国家自然科学基金（面上项目） |
2015-01~2018-12
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50万元
| 课题负责人 |
| 12ZR141890 | 肝移植患者霉酚酸及代谢物肝肠循环中转运体调控机制研究 | 上海自然科学基金 |
2012-06~2015-06
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10万元
| 课题负责人 |
- 学术论文
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Rui WB, An HM, Shao K, Zhai XH, Lu JQ, Hu SS,, Zhou PJ.
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Limited Sampling Strategy for the Estimation of the Area under the Concentration-Time Curve for Ganciclovir in Chinese Adult Renal Allograft Recipients.
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Eur J Clin Pharmol.
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2019
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75(5):677-686
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, Shao K, An HM, Shi HQ, Lu JQ, Zhai XH, Liu XX, Wang XH, Xu D, Zhou PJ.
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Population Pharmacokinetics and Bayesian Estimation of Mycophenolic Acid Exposure in Chinese Renal Allograft Recipients After Administration of EC-MPS.
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J Clin Pharmacol.
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2019
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59(4): 578-589
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夏 琴,姜慧婷,支建明,
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霉酚酸在大鼠体内的肠肝循环模型
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药学服务与研究
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2018
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18(1): 21-24
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陆佳倩,刘晓雪,陈皓,
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有限取样法估算中国肝移植患者服用霉酚酸钠肠溶片后霉酚酸及其代谢物的体内暴露量
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中国临床药学杂志
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2018
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27(1): 8-11
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Ouyang Y,, Pan X, Wang Z, Ren H, Xu Y, Ni L, Yu X, Yang L, Chen N.
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Clinical significance of plasma globotriaosylsphingosine levels in Chinese patients with Fabry disease.
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Exp Ther Med.
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2018
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15(4): 3733-3742.
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石浩强,何娟,陆佳倩,毛恩强,车在前,
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LC-MS/MS及HPLC法检测利奈唑胺血药浓度及临床应用
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中国药师
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2017
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20(10): 1718-23
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, Shi HQ, Liu XX, Zhang WX, Lu JQ, Xu BM, Chen H.
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Population pharmacokinetics and Bayesian estimation of tacrolimus exposure in Chinese liver transplant patients.
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J Clin Pharm Ther.
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2017
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42(6):679-688.
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许倍铭,
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新型抗癫痫药物的药物监测进展
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中国药房
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2017
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28(35): 5036-5037
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Shi HQ, Zhang Y, Cheng MH, Fan BS, Tian JS, Yu JG, Yu JG,
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Sodium sulfide, a hydrogen sulfide-releasing molecule, attenuates acute cerebral ischemia in rats.
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CNS neuroscience & Therapeutics
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2016
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22(7): 625-32.
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Shi HQ, Yang J, Zhang LQ, Xu BM, Lu HL, Chen EZ,
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The population pharmacokinetics of sirolimus and CYP3A5*3 polymorphism in Chinese renal transplant patients.
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Int J Clin Exp Med.
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2016
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9(3): 5354-66
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刘晓雪,黄菁菁,夏琴,杨婉花,
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LC-MS/MS法同时测定人血浆中霉酚酸及其代谢物浓度及其在肝移植患者药动学研究中应用
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中国医院药学杂志
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2015
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35(23): 2096-2101
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刘晓雪,黄菁菁,夏琴,杨婉花,
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LC-MS/MS法同时测定人血浆中霉酚酸及其代谢物浓度及其在肝移植患者药动学研究中应用
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中国医院药学杂志
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2015
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35(23): 2096-2101
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夏琴,,刘晓雪,黄菁菁,支建明
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中国肝移植患者服用霉酚酸钠肠溶片后霉酚酸及其代谢物的药动学研究
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中国药师
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2015
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18(4):533-537
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刘晓雪,
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CYP3A5和MDR1基因多态性对中国肝移植患者他克莫司药代动力学参数的影响
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中国临床药学杂志
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2014
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23(5): 283-7
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Chen H,
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Clinical mycophenolic acid monitoring in liver transplant recipients
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World J Gastroenterol
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2014
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20(31): 10715-28
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刘晓雪,
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与肝肠循环相关的转运体及其基因多态性
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中国药师
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2013
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16(4): 618-621
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, Xu YP, Jiang T, Feng R, Sun J, Zhang WX, Yang WH, Li J, Adeniyi O, Chen HZ.
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Estimation of CYP2D6*10 genotypes on citalopram disposition in Chinese subjects by population pharmacokinetic assay
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J Clin Pharm Ther.
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2013
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38: 504-11
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Gu ZD,, Song YY, Shen BY, Zhang WX,2 Xie JJ, Deng XX, Fan QS, Chen H
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Pharmacokinetics of Free Mycophenolic Acid and Limited Sampling Strategy for the Estimation of Area Under the Curve in Liver Transplant Patients
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European Journal of Pharmaceutical ciences
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2012
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47:636-41
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,蔡卫民,杨婉花
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CYP2D6基因多态性与抗精神病药物的个体化应用
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中国临床药理学与治疗学杂志
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2012
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17(9):1067-1074
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,杨婉花
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群体药动学在万古霉素治疗药物监测的应用
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中国临床药理学杂志
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2011
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27(9):13-17
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, Zhang WX, Gu ZD, Li J, Zhang YX, Cai WM
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Population pharmacokinetic study of cyclosporine in Chinese renal transplant recipients
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Eur J Clin Pharmacol
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2011
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67(6):601-612
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, Gu ZD, Chen H, Zhang WX, Fen XJ,Cai WM, Fan QS
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Establishment of HPLC fluorescence and EMIT methods for determination of free mycophenolic acid and its application in Chinese liver transplant recipients
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Ther Drug Monit
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2010
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32(5):653-670
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石浩强, 许倍铭,
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中国肾移植患者中不同的 CYP3A5*3 基因型与西罗莫司血药浓度的关系
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中国医药工业杂志
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2010
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41(9):678-682
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, 蔡卫民
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群体药动学在免疫抑制剂合理用药中的应用
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中国药理学通报
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2010
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26(2):159-62
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, Fang J, Zhang WX, Jin Z, Yu ZC, Cai WM.
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Detection of C1236T, G2677T/A and C3435T polymorphism of MDR1 by amplification refractory mutation system PCR.
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Journal of Clinical laboratory analysis
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2009
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23:110-6.
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Shen BY,, Zhang WX, Mao HR, Shen C, Deng XX, Zhan X, Chen H.
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Comparison of pharmacokinetics of mycophenolic acid and its metabolites between living donor liver transplant recipients and deceased donor liver transplant recipients.
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Liver Transpl
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2009
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15(11):1473-80
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, Cai WM, Li JH, Cao XM.
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Estimating N-acetyltransferase metabolic activity and pharmacokinetic parameters of isoniazid from genotypes in Chinese subjects.
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Clinica Chimica Acta
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2009
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405:23-9
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, Zhang W, Fang J, Jin Z, Li J, Cai WM.
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Influence of the MDR1 haplotype and CYP3A5 genotypes on cyclosporine blood level in Chinese renal transplant recipients.
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Xenobiotica
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2009
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39(12):931-8
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Zhang WX,, Jin Z, Yu Z, Wang X, Chen H, Mao A, Cai W.
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Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients.
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Xenobiotica
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2008
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38(11):1422-36.
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, Zhang WX, Yu ZC, Cai WM.
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Determination of Mycophenolic Acid (MPA) and Its Acyl and Phenol Glucuronide Metabolits Simultaneously in Human Plasma by a Simplified HPLC Method.
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Analytical Letter
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2007
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40(13):2465-75
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Cai WM,, Zhang WX.
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Frequency of CYP2D6 *10 and *14 alleles and their influence on the metabolic activity of CYP2D6 in a healthy Chinese population.
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Clin Pharmacol Ther
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2007
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81(1):95-8
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, Li JH, Xu YM, Wang J, Cao XM
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The influence of NAT2 genotypes on the plasma concentration of isoniazid and acetylisoniazid in Chinese pulmonary tuberculosis patients.
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Clinica Chimica Acta
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2006
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365:104-8
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, Zhang WX, Cai WM
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The influence of various genotypes on the metabolic activity of NAT2 in a Chinese population.
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Eur J Clin Pharmacol
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2006
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62:355-9
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, Cai WM.
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Influence of CYP2D6*10B genotype on pharmacokinetics of propafenone enantiomers in Chinese subjects.
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Acta Pharmacol Sin
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2003
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24(12):1277-80
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