• 基本信息
    导师姓名: 徐健 学科代码: 100202
    性别: 学科名称: 儿科学
    培养单位: 附属国际和平妇幼保健院 三级学科
    导师类型: 博士生导师 专业领域名称: 儿科学 专业学位
    联系方式: sonia0616@sina.com 专业领域代码: 105102
    邮编: 200092 邮箱地址: sonia0616@sina.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    中国毒理学会神经毒理学分会会员
    中华医学会公共卫生分会青年委员会副主任委员
    国际环境流行病学会会员
    上海预防医学会青年委员
    上海市微量元素学会秘书长
    上海市微量元素学会理事
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    81974486发育期过度学习负担对神经行为发育影响的流行病学和相关基础研究国家自然基金面上项目 2020-01~2023-12 54万元  课题负责人
    2017生命早期维生素A暴露对婴幼儿神经发育的影响高峰高原计划 2017-07~2020-06 100万元  课题负责人
    201640363铅和精神压力复合暴露对育龄女性生殖功能的影响及易感性研究上海市卫计委 2017-01~2019-12 5万元  课题负责人
    81673189BDNF-TrkB-ERK通路在妊娠期铅和精神压力复合暴露影响子代认知发育中的作用机制研究国家自然基金面上项目 2017-01~2020-12 45万元  课题负责人
    81373016基于铅的骨血转化模式探讨不同年龄段铅中毒儿童治疗的差异性 国家自然基金面上项目 2014-01~2017-12 70万元  课题负责人
    124119a1400KXRF技术测定骨铅在铅中毒儿童诊疗中的应用探讨上海市科委 2012-10~2015-09 10万元  课题负责人
    SQ2010CB053224我国儿童铅中毒机制及防治策略研究国家973计划 2012-03~2016-09 476万元  课题参与人
    10QA1405700妊娠期过度压力对仔鼠学习记忆的影响及影响机制的研究上海市科委 2010-04~2012-04 15万元  课题负责人
    20901205妊娠期压力对子代神经发育影响的流行病学及相关基础研究国家自然基金青年基金 2010-01~2012-12 19万元  课题负责人
    06BZ002青少年网络成瘾的神经生物学机制探讨上海市教委,发展基金 2007-01~2008-12 6万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Huang L, Jiang S,, Lei X, Zhang J.  Associations between prepregnancy body mass index, gestational weight gain and weight catch-up in small-for-gestational-age children  Maternal & Child Nutrition  2021  Jul 22:e13235.  
    Guo X, Zhou L,, Liu Z, Liu J, Yan C.  Prenatal Maternal Low Selenium, High Thyrotropin, and Low Birth Weights.   Biol Trace Elem Res.  2021  199(1):18-25. 
    Jiang S, Yang B,, Liu Z, Yan C, Zhang J, Li S, Shen X.  Associations of Internal-Migration Status with Maternal Exposure to Stress, Lead, and Selenium Deficiency Among Pregnant Women in Shanghai, China.  Biol Trace Elem Res.  2019  190(2):309-317. 
    Lin Y, Huang L,, Specht AJ, Yan C, Geng H, Shen X, Nie LH, Hu H.  Blood lead, bone lead and child attention-deficit-hyperactivity-disorder-like behavior.  Sci Total Environ.   2019  659:161-167.  
    ,邱晓露主译  自闭症谱系障碍儿童学习风格简介(第一版)  世界图书出版社  2019  译著 
    , Hu H, Wright R, Schnaas L, Bellinger DC, Park SK, Wright RO, Téllez-Rojo MM.  Prenatal lead exposure modifies the association of maternal self-esteem with child adaptive ability.  Int J Hyg Environ Health.  2019  222(1):68-75. 
    Zhang Y, Zhou L, Li S, Liu J, Sun S, Ji X, Yan C,  Impacts of lead exposure and chelation therapy on bone metabolism during different developmental stages of rats.  Ecotoxicol Environ Saf.   2019  183:109441.  
    Yi Hu, Lin Ji, Yan Zhang, Rong Shi, Wenchao Han, Lap Ah Tse, Rui Pan, Yiwen Wang, Guodong Ding,, Qingying Zhang, Yu Gao, Ying Tian, Shanghai Birth Cohort Study.   Organophosphate and Pyrethroid Pesticide Exposures Measured before Conception and Associations with Time to Pregnancy in Chinese Couples Enrolled in the Shanghai Birth Cohort.  Environ Health Perspect.   2018  126(7): 077001.  
    副主译  公共卫生实践中的流行病学  人民卫生出版社  2018  译著 
    Huo X, Chu S, Hua L, Bao Y, Du L,, Zhang J.  The effect of breastfeeding on the risk of asthma in high-risk children: a case-control study in Shanghai, China.  BMC Pregnancy Childbirth.  2018  18(1):341. 
    Specht AJ, Lin Y,, Weisskopf M, Nie LH.   Bone lead levels in an environmentally exposed elderly population in shanghai, China.  Sci Total Environ.   2018  626:96-98.  
      妊娠期压力与子代发育.  中华围产医学杂志  2018  21(2) : 90-93. 
    Ying XL, Gao ZY, Yan J, Zhang M, Wang J,, Markowitz M, Yan CH.  Sources, symptoms and characteristics of childhood lead poisoning: experience from a lead specialty clinic in China.  Clin Toxicol (Phila).  2018  56(6):397-403.  
    颜崇淮(主译),李廷玉(主译),,赵勇(副主译)  环境与儿童健康(美国儿科学会环境健康委员会主编,第三版)  世界图书出版社  2017  译著 
    Zhou L,, Zhang J, Yan C, Lin Y, Jia Y, Hu W.  Prenatal maternal stress in relation to the effects of prenatal lead exposure on toddler cognitive development.  Neurotoxicology.   2017  59:71-78. 
    Lin Y,, Huang J, Jia Y, Zhang J, Yan C, Zhang J.  Effects of prenatal and postnatal maternal emotional stress on toddlers' cognitive and temperamental development.  J Affect Disord.  2017  207:9-17.  
    Lin Y, Zhou L,, Luo Z, Kan H, Zhang J, Yan C, Zhang J.  The impacts of air pollution on maternal stress during pregnancy.  Sci Rep  2017  7:40956. 
    Specht AJ, Mostafaei F, Lin Y,, Nie LH.  Measurements of Strontium Levels in Human Bone In Vivo Using Portable X-ray Fluorescence (XRF).  Appl Spectrosc.  2017  71(8):1962-1968. 
    Lin Y, Hu W,, Luo Z, Ye X, Yan C, Liu Z, Tong S.  Association between temperature and maternal stress during pregnancy.  Environ Res.   2017  158:421-430 
    Specht AJ, Lin Y, Weisskopf M, Yan C, Hu H,, Nie LH.  XRF-measured bone lead (Pb) as a biomarker for Pb exposure and toxicity among children diagnosed with Pb poisoning.  Biomarkers.  2016  21(4):347-52. 
    , Yan CH, Hu H, Wu MQ, Shen XM.  Prenatal Maternal Occupational Exposure and Postnatal Child Exposure to Elemental Mercury.  Pediatr Emerg Care  2016  32(3):175-9.  
      第四节:新生儿硒代谢与功能,第七章:新生儿其他微量元素代谢与功能  《新生儿营养学》第2版第十章第四节和第七节,人民卫生出版社  2016  专著 
    Li S,, Liu Z, Yan CH.  The non-linear association between low-level lead exposure and maternal stress among pregnant women  Neurotoxicology.   2016  2016 Jul 7. pii: S0161-813X(16)30123-1. 
    , Hu H, Wright R, Sánchez BN, Schnaas L, Bellinger DC, Park SK, Martínez S, Hernández-Avila M, Téllez-Rojo MM, Wright RO.  Prenatal Lead Exposure Modifies the Impact of Maternal Self-Esteem on Children's Inattention Behavior  J Pediatr  2015  共同通讯(排第一),167(2):435-41 
    Cao J, Gao Z, Yan J, Li M, Su J,, Yan CH  Evaluation of Trace Elements and Their Relationship with Growth and Development of Young Children.  Biol Trace Elem Res  2015  共同通讯作者(排第一),2015 Oct 19. [Epub ahead of print] 
    Li MM, Wu MQ,, Du J, Yan CH  Body burden of hg in different bio-samples of mothers in shenyang city, china.  PLoS One.  2014  9(5):e98121-2 
    Li MM, Cao J,, Cai SZ, Shen XM, Yan CH.  The national trend of blood lead levels among Chinese children aged 0-18years old, 1990-2012.  Environ Int.  2014  4;71C:109-117 
    , Shen LX, Yan CH, Hu H, Yang F, Wang L, Kotha SR, Ouyang F, Zhang LN, Liao XP, Zhang J, Zhang JS, Shen XM.  Parent-adolescent interaction and risk of adolescent internet addiction: a population-based study in Shanghai.  BMC Psychiatry.  2014  2014 Apr 15;14:112.  
    Guo BQ, Cai SZ, Guo JL,, Wu W, Li H, Zhou X, Kim DS, Yan CH, Lü HD.  Levels of prenatal mercury exposure and their relationships to neonatal anthropometry in Wujiang City, China.  Environ Pollut.  2013  182:184-9. 
    , Yang B, Yan CH, Hu H, Cai S, Liu J, Wu M, Ouyang F, Shen X.  Effects of duration and timing of prenatal stress on hippocampal myelination and synaptophysin expression  Brain Res  2013  共同通讯作者(排第一)1527:57-66 
    Wu MQ, Yan CH#,, Wu W, Li H, Zhou X  Umbilical cord blood mercury levels in China  J Environ Sci  2013  25:1–7 
    Yan CH,, Shen XM.  Childhood Lead Poisoning in China: Challenges and Opportunities.  Environ Health Perspect  2013  121:294-295 
    , Shen LX, Yan CH, Hu H, Yang F, Wang L, Kotha SR, Zhang LN, Liao XP, Zhang J, Ouyang FX, Zhang JS, Shen XM.  Personal characteristics related to the risk of adolescent internet addiction: a survey in Shanghai, China.  BMC Public health  2012  12(1):1106 
    ,颜崇淮,沈晓明.  妊娠期压力对子代神经发育影响的流行病学及相关机制研究.   中华预 防医学杂志  2010  44(5):455-457 
    颜崇淮,,沈晓明.   第 59 章:铅中毒性神经系统损害.  《小儿神经系统疾病:基础与临床》 第 2 版,人民卫生出版社  2009  专著 
    , Yan CH,Yang B,Tong SL, Zou XY, Tian Y.  Effects of lead exposure on hippocampal metabotropic glutamate receptor subtype 3 and 7 in developmental rats.   Journal of Negative Results in BioMedicine.  2009  Apr 20;8:5. 
    , Yan CH,Yang B, Xie HF, Zou XY, Zhong L, Gao Y, Tian Y, Shen XM.  The role of metabotropic glutamate receptor 5 in developmental lead neurotoxicity  Toxicology Letters  2009  191: 223-230. 
    , 颜崇淮, 沈晓明, 余高妍, 余晓刚, 张燕萍.   小儿中重度铅中毒25例发病原因及疗效分析.  中国实用儿科杂志  2008  23(9): 670-672 
    , 沈理笑, 颜崇淮, 吴增强, 马珍珍, 金星明, 沈晓明.   上海市青少年互联网使用现状调查.  中华预 防医学杂志  2008  42(10):735-738 
    李筑英, 颜崇淮,, 黄华, 邹向宇.  妊娠压力与铅联合暴露对大鼠子代空间学习记忆的影响.  中华预防医学杂志  2008  42(10): 717-721 
    , 颜崇淮, 沈晓明  基因芯片筛查出生前后铅暴露对幼鼠海马基因表达的影响  中国公共卫生  2008  24(3): 317-319 
    , Yan CH, Wu SH, Yu XD, Yu XG, Shen XM.   Developmental lead exposure alters gene expression of metabotropic glutamate receptors in rat hippocampal neurons.  neuroscience lett  2007  413:222-226