- 基本信息
导师姓名:
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张雁云
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学科代码:
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100100
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性别:
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男
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学科名称:
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基础医学
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培养单位:
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基础医学院
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三级学科
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导师类型:
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博士生导师
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专业领域名称:
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联系方式:
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上海市黄浦区重庆南路225号健康科学研究所1号楼306室
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专业领域代码:
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邮编:
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200025
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邮箱地址:
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yyzhang@sibs.ac.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
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美国血液学学会会员
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美国免疫学学会会员
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《现代免疫学》期刊主编
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中国免疫学学会理事
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美国免疫学学会会员
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- 科研项目
81373164 | 组蛋白乙酰化/去乙酰化表观调控效应型记忆CD8+T细胞及其防治GVHD的研究 | 国家自然科学基金 |
2014-01~2017-12
|
70万元
| 课题负责人 |
81130057 | 间充质干细胞治疗肝衰竭的细胞与分子机制研究 | 国家自然科学基金重点项目 |
2012-01~2016-12
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240万元
| 课题负责人 |
11JC1411400 | 诱导抑制性树突状细胞干预多发性硬化的机制及新策略 | 上海市科委基础研究重点项目 |
2012-01~2014-12
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50万元
| 课题负责人 |
11431920900 | 利尿钠肽等心衰治疗药物的研究 | 上海市科委重点科技攻关 |
2011-11~2014-09
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80万元
| 课题负责人 |
81071748 | 肿瘤干细胞自噬性死亡中趋化因子受体CXCR4调控及干预机制研究 | 国家自然基金委,面上项目 |
2011-01~2013-12
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38万元
| 课题负责人 |
2011CB966200 | 组织干细胞在器官衰老与再生中的作用及调控机制研究 | 973项目重大科学研究计划 |
2011-01~2015-12
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2500万元
| 课题负责人 |
09431901000 | 长效重组人胰高血糖素样多肽-1药物的临床前研究 | 上海市科委,重点科技攻关 |
2009-11~2012-10
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50万元
| 课题负责人 |
30873045 | IDO/TTS平衡格局与肿瘤干细胞免疫逃逸调控机制关系研究 | 国家自然基金委,面上项目 |
2009-01~2011-12
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30万元
| 课题负责人 |
074319102 | 胚胎肝造血干细胞分离纯化新策略和实验性治疗应用的研究 | 上海市科委,重点科技攻关 |
2007-11~2009-10
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70万元
| 课题负责人 |
30670911 | 趋化因子及其受体介导异体效应型记忆CD8+ T细胞致移植物抗宿主病作用及靶向干预研究 | 国家自然基金委,面上项目 |
2007-01~2009-12
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27万元
| 课题负责人 |
08JC1413300 | 类风湿性关节炎遗传相关性、免疫病理机制及新型免疫调节剂实验性治疗策略研究 | 上海市科委,基础重点项目 |
~2010-09
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25万元
| |
09431901000 | 长效重组人胰高血糖素样多肽-1药物的临床前研究 | 上海市科委,生物医药重点重大项目资助 |
~
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0万元
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- 学术论文
Dang S, Xu H, Xu C, Cai W, Li Q, Cheng Y, Jin M, Wang RX, Peng Y, Zhang Y, Wu C, He X, Wan B,
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Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis
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Autophagy
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2014
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10(7):1301-1315
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Zhang Y, Cai W, Huang Q, Gu Y, Shi Y, Huang J, Zhao F, Liu Q, Wei X, Jin M, Wu C, Xie Q, Zhang Y, Wan B,
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Mesenchymal Stem Cells Alleviate Bacteria-Induced Liver Injury in Mice by Inducing Regulatory Dendritic Cells
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Hepatology
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2014
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59(2):671-682
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Tan W, Meng Y, Li H, Chen Y, Han S, Zeng J, Huang A, Li B,, Guo Y
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A bispecific antibody against two different epitopes on hepatitis B surface antigen has potent hepatitis B virus neutralizing activity
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mAbs
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2013
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6():945-953
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Wu Q, Wang H, Zhao X, Shi Y, Jin M, Wan B, Xu H, Cheng Y, Ge H,
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Identification of G-protein-coupled receptor 120 as a tumor-promoting receptor that induces angiogenesis and migration in human colorectal carcinoma
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Oncogene
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2013
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32():5541-5550
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Xu J, Zhang Y, Xiao Y, Ma S, Liu Q, Dang S, Jin M, Shi Y, Wan B,
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Inhibition of 12/15-lipoxygenase by baicalein induces microglia PPARβ/δ: a potential therapeutic role for CNS autoimmune disease
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Cell Death & Disease
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2013
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2013(86):-
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Gu Q, Wu Q, Jin M, Xiao Y, Xu J, Mao C, Zhao F, Zhang Y,
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Heme oxygenase-1 alleviates mouse hepatic failure through suppression of adaptive immune responses
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J Pharmacol Exp Ther
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2012
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340(1):2-10
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Mao C , Wang S , Xiao Y , Xu J , Jiang Q , Jin M , Jiang X , Guo H , Ning G ,
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Impairment of Regulatory Capacity of CD4+CD25+ Regulatory T Cells Mediated by Dendritic Cell Polarization and Hyperthyroidism in Graves’ Disease
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The Journal of Immunology
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2011
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186(8): 4734-43
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Zhao F, Zhang Y, Wang H, Jin M, S, He S, Shi Y, Guo Y,
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Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host disease
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Blood
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2011
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1179(5):1723-33
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Xu H, Wu Q, Dang S, Jin M, Xu J, Cheng Y, Pan M, Wu Y, Zhang C,
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Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma
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PLoS One
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2011
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6(12):27398-e27399
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Cao Q, Jin Y, Jin M, He S, Gu Q, He S, Qiu Y, Ge H, Yoneyama H,
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Therapeutic effect of MIP-1alpha-recruited dendritic cells on preestablished solid and metastatic tumors
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Cancer Letters
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2010
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295(1):17-26
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Xiao Y, Xu J, Wang S, Mao C, Jin M, Ning G, Xu J,
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Genetic ablation of steroid receptor coactivator-3 promotes PPAR-beta-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis
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Glia
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2010
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58(8):932-42
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Zhang C, Hao L, Wang L, Xiao Y, Ge H, Zhu Z, Luo Y, Zhang Y,
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Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node etastasis in human colorectal cancer
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BMC Cancer
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2010
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10:184-95
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Xiao Y, Xu J, Mao C, Jin M, Wu Q, Zou J, Gu Q, Zhang Y,
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18β-glycyrrhetinic acid ameliorated Propionibacterium acnes-induced acute liver injury through inhibition of MIP-1α
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The Journal of Biological Chemistry
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2010
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285(2):1128-37
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Xiao Y,
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Suppressor of cytokine signaling-1, a possible cause for regulatory T cells in hepatitis
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Hepatology
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2008
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48(4):1353-53
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He S, Cao Q, Qiu Y, Mi J, Zhang J Z, Matsushima K, Jin M, Ge H, Emerson S, Zhang Y,
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A new approach of blocking alloreactive T cell-mediated GVHD by in vivo administration of anti-CXCR3 neutralizing antibody
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The Journal of Immunology
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2008
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181(11):7581-92
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Xu J, Zhou T,
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Role of dendritic cells and chemokines in acute graft-versus-host disease
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Frontiers in bioscience
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2008
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13:2065-74
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He S, Cao Q, Yoneyama H, Ge H,
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MIP-3(alpha) and MIP-1(alpha) rapidly mobilize dendritic cell precursors into the peripheral blood
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Journal of Leukocyte Biology
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2008
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84(6):1549-56
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Hao L, Zhang C, Qiu Y, Wang L, Luo Y, Jin M, Zhang Y, Guo B, Matsushima K,
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Recombination of CXCR4, VEGF, and MMP-9 predicting lymph node metastasis in human breast cancer
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Cancer Letters
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2007
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253(1):34-42
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Zhu L, Ji F, Wang Y, Zhang Y, Liu Q, Zhang J Z, Matsushima K, Zhang D,
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Synovial autoreactive T cells in rheumatoid arthritis resist indoleamine IDO-mediated inhibition
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The Journal of Immunology
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2006
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177(11):8226-33
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, Yoneyama H, Wang Y, Onai N, Ishikawa S
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Mobilization of dendritic cell precursors into the circulation by administration of MIP-1alpha in mice
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Journal of the National Cancer Institute
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2004
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96(3):201-9
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Yoneyama H, Matsuno K,, Nishiwaki T, Kitabatake M
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Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules
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International Immunology
|
2004
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16(7):915-28
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Yoneyama H, Narumi S,, Murai M, Baggiolini M
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Pivotal role of dendritic cell-derived CXCL 10 in the retention of T helper cell 1 lymphocytes in the secondary lymph nodes
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Journal of Experimental Medicine
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2002
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195(10):1257-66
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Onai N, Kitabatake M,, Kitamura T, Ishikawa H
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Pivotal role of CCL25 (TECK)/CCR9 in the formation of gut cryptopatches and consequent appearance of intestinal intraepithelial T lymphocytes
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International Immunology
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2002
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14(7):687-694
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Wang Y,, Onai N, Yoneyama H, Hashimoto S
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Pivotal role of dendritic cell-derived CXCL 10 in the retention of T helper cell 1 lymphocytes in the secondary lymph nodes
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Blood
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2002
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96(3):201-9
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Yoneyama H, Matsuno K,, Murai M, Itakura M
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Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue in a granulomatous liver disease
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Journal of Experimental Medicine
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2001
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193(1):35-49
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, Wang Y, Ogata M, Hashimoto S
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Development of dendritic cells in vitro from murine fetal liver-derived lineage phenotype-negative c-kit+ hematopoietic progenitor cells
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Blood
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2000
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95(1):138-46
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Onai N,, Yoneyama H, Kitamura T and Matsushima K
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Impairment of Lymphopoiesis and myelopoiesis in mice reconstituted with bone marrow-hematopoietic progenitor cells expressing SDF-1-Intrakine
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Blood
|
2000
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96(6):2074-80
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Ogata M, Zhang Y, Wang Y, Itakura M,
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Chemotactic response toward chemokines and its regulation by transforming growth factor-β1 of bone marrow hematopoietic progenitor cell-derived different subset of dendritic cells
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Blood
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1999
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93(10):3225-32
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Zhang Y,, Ogata M, Chen P, Harada A
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Transforming growth factor-polarizes murine hematopoietic progenitor cells to generate Langerhans cell-like dendritic cells through monocyte/macrophage differentiation pathway
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Blood
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1999
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93(4):1208-20
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Zhang Y, Harada A, Wang J-B,, Hashimoto S
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Bifurcated dendritic cell differentiation in vitro from murine lineage phenotype-negative c-kit+ bone marrow hematopoietic progenitor cells
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Blood
|
1998
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92(1):118-28
|
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