• 基本信息
    导师姓名： 姜丽岩 学科代码： 100201
    性别： 女 学科名称： 内科学
    培养单位： 附属胸科医院 三级学科 呼吸系病
    导师类型： 博士生导师 专业领域名称： 内科学 专业学位
    联系方式： 13916146759 专业领域代码： 105101
    邮编： 200030 邮箱地址： jiang_liyan2000@126.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    中华医学会上海市呼吸分会肺癌学组副组长
    国家科技专家库评审专家
    上海市医药青联委员
    上海市康复医学会呼吸康复专业委员会运动康复学组副组长
    CSCO会员
    人力资源社会保障（中国博士后科学基金评审专家）
    Shanghai Chest 杂志副主编
    Members of the IASLC Staging and Prognostic Factors Committee
    上海科学技术奖评审专家
    中华医学会呼吸分会肺癌学组委员
    中国医师协会中西医结合呼吸病专委会常委
    《Annals of oncology》中文版编委
    上海市抗癌协会肿瘤呼吸内镜专业委员会副主任委员
    上海市医学会第四届医疗鉴定专家库成员
    《Oncotarget》审稿人
    《国际呼吸杂志》编委
    中国医药教育协会常务理事
    中国医药教育协会肺部肿瘤专委会主任委员
    《The Clinical Respiratory Journal》审稿人
    ASCO会员
    上海市卫生系列高级专业技术职务任职资格评委会专家
    《Cancer Letters》审稿人
    中国康复医学会上海呼吸分会委员
    上海市知联会委员
    《中华现代内科学杂志》常务编委
    中国医药教育协会肺部肿瘤专委会主任委员
    《中国肺癌杂志》审稿人
    CFDA上海市胸科医院药物临床试验机构办公室主任
    上海市卫生局新苑新星
    中华医学会呼吸分会肺癌学组委员
    上海市青联委员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    82150005基于微肿瘤模型开展肿瘤异质性分子机制研究国自然 专项项目 专家推荐类远创探索计划项目 2022-06~2025-06 200万元  课题负责人
    Y-2019AZZD-0038基于多位点磁球富集CTC-高通量检测系统探讨非小细胞 肺癌EGFR-TKI获得性耐药的新机制：一项前瞻性、多中心临床研究希思科—领航肿瘤研究基金重点项目 2020-07~2023-07 100万元  课题负责人
    YS2018YFC130103慢阻肺康复体系和策略的建立及其临床应用性研究科技部 2018-07~2021-08 1250万元  子课题负责人
    2017YFC0907905肺癌专病队列研究--肺癌复发转移分子标志物监测队列科技部 2017-07~2020-12 20万元  课题参与人
    17411971100血清外泌体microRNA在肺结节良恶性辅助鉴别诊断中的临床研究上海市科委2017年度医学引导类（中、西医）科技项目 2017-06~2020-06 20万元  课题负责人
    0000000肺癌专病队列2017年度国家重点研发计划“精准医学研究”重点专项 2017-02~2021-02 35万元  课题参与人
    2016HP041肺癌患者门诊化疗模式的优化与管理上海市卫生和计划生育委员会卫生计生政策研究自选课题 2016-06~2016-12 10万元  课题负责人
    15411961500循环肿瘤细胞计数及其动态变化在肺腺癌化疗及EGFR-TKI靶向治疗预测领域的应用上海市科委2015年度医学引导类（中、西医）科技项目 2015-10~2018-09 30万元  课题负责人
    81472175非小细胞肺癌相关LncRNAs的发现及其对靶向mRNA的调控国家自然基金 2015-01~2018-12 54万元  课题负责人
    CCCX-3-3001养阴解毒方联合EGFR—TKI对晚期肺腺癌患者PFS影响的随机对照临床研究中医药传承和创新发展类-中医药创新内涵建设 2014-09~2016-12 50万元  子课题负责人
    2014YZDC10400反馈系统控制优化组合药物技术应用于NSCLC术后辅助化疗的研究院级重大课题 2014-07~2017-06 50万元  课题负责人
    20134007上海地区汉族人群肺腺癌EGFR-TKI靶向治疗预后预测研究 2013年度上海市卫生和计划生育委员会委级科研项目-重点项目 2014-01~2016-12 10万元  主要责任人
    134307205002013年IL-6/JAK/STAT3信号通路在间歇低氧所致胰岛素抵抗中的作用 2013年上海市国际科技合作基金项目 2013-06~2015-06 40万元  子课题负责人
    SCHEMESCHEME 肺癌的发病机制和分子分类的研究国际合作课题（中美合作转化医学课题） 2011-10~2017-12 520万元  课题负责人
    09JC1413000小分子代谢产物在肺癌早期诊断中的应用研究上海市科委基础重点项目 2009-09~2011-08 25万元  课题负责人
     肺癌信息化管理平台建设上海交大医工（理）交叉基金 ~ 5万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Mao X, Hu F, Peng J, Zhao Y, Gu A, Fang W, Wang M, Zheng D, Chen G, Dong X, Tan X, Chen Y, Liu X, Cheng X, Zhang X, Hong Q, Hu J, Wang J, Xu Y, Li F, Liang X, Li S,  Expert consensus on multi-disciplinary treatment, whole-course pulmonary rehabilitation management in patients with lung cancer and chronic obstructive lung disease.  Ann Palliat Med  2022  2022 May;11(5):1605-1623 
    Mao Xiaowei,Liu Jiabing,Hu Fang et al  Serum NSE is Early Marker of Transformed Neuroendocrine Tumor After EGFR-TKI Treatment of Lung Adenocarcinoma  Cancer Manag Res  2022  2022, 14: 1293-1302 
    Hu F, Peng J, Mao X, Niu Y, Ma M, Zhao Y, Gu A,  Prognosis of different extrathoracic metastasis patterns in patients with M1c lung adenocarcinoma receiving immunotherapy  J Cancer Res Clin Oncol  2022  2022 Jul 27 
    Xiaowei Mao,Wei Zhang,Qiang Wang et al  Assessment of systemic immune-inflammation index in predicting postoperative pulmonary complications in patients undergoing lung cancer resection.[J] ., 2022, 172: 365-370  Surgery  2022  Surgery, 2022, 172: 365-370 
    Mao Xiaowei, Ni Yiqian, Niu Yanjie,  Using T Stage and Tumor Thrombus as Predictive Factors for Patients with Resected I-IIA Small Cell Lung Cancer: A Retrospective Study,   Translational Cancer Research,   2021  2021 accept 
    Hai Zhang#, Yun Song#, Xiaowei Mao#, Feng Pan, Yan Pan,  Cognitive status of nurses in Shanghai on pulmonary rehabilitation  Ann Palliat Med  2021  2021 Feb;10(2):2184-2194.  
    Botai Li#, Lili Zhu#, Chunlai Lu#, Cun Wang, Hui Wang, Haojie Jin, Xuhui Ma, Zhuoan Cheng, Chengtao Yu, Siying Wang, Qiaozhu Zuo, Yangyang Zhou, Jun Wang, Chen Yang, Yuanyuan Lv, Liyan Jiang*,  circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity  Nat Commun  2021  2021 Jan 12;12(1):295 
    Tao Jiang#,, Xiaorong Dong#, Kangsheng Gu#, Yueyin Pan, Qin Shi, Guojun Zhang, Huijuan Wang, Xiaochun Zhang, Nong Yang, Yuping Li, Jianping Xiong, Tienan Yi, Min Peng, Yong Song, Yun Fan, Jiuwei Cui, Gongyan Chen, Wei Tan, Aimin Zang, Qisen Guo, Guangqiang Zhao, Ziping Wang, Jianxing He, Wenxiu Yao, Xiaohong Wu, Kai Chen, Xiaohua Hu, Chunhong Hu, Lu Yue, Da Jiang, Guangfa Wang, Junfeng Liu, Guohua Yu, Junling Li, Henghui Zhang, Lihong Wu, Lu Fang, Dandan Liang, Yi Zhao, Weihong Zhao, Wenmin Xie, Shengxiang Ren*, Caicun Zhou*  Utilization of circulating cell-free DNA profiling to guide first-line chemotherapy in advanced lung squamous cell carcinoma  Theranostics  2021  2021 Jan 1;11(1):257-267. 
    Fang Hu#, Yanjie Niu#, Xiaowei Mao, Jiangtao Cui, Xiaoting Wu, Wenxin Qin*,  tsRNA-5001a promotes proliferation of lung adenocarcinoma cells and is associated with postoperative recurrence of lung adenocarcinoma patients  Translational Lung Cancer Research  2021  2021 accept 
    Xiaowei Mao, Wei Zhang, Yiqian Ni, Yanjie Niu,  A prediction model for postoperative pulmonary complication in pulmonary function-impaired patients following lung resection.   Journal of Multidisciplinary Healthcare .   2021  2021 accept 
    Mao Xiaowei, Ni Yiqian, Niu Yanjie,  The clinical value of pulmonary rehabilitation in reducing postoperative complications and mortality of lung cancer resection- a systematic review and meta-analysis  Frontiers in Surgery  2021  2021 accept 
    Yu C#, Cheng Z#, Cui S#, Mao X, Li B, Fu Y, Wang H, Jin H, Ye Q, Zhao X, Jiang L*,  circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D.   J Exp Clin Cancer Res.   2020  2020 Mar 30;39(1):55 
    Jie-Qiong Song#,, Cui-Ping Fu#, Xu Wu, Zi-Long Liu, Liang Xie, Xiao-Dan Wu, Sheng-Yu Hao*, Shan-Qun Li*  Heterozygous SOD2 deletion deteriorated chronic intermittent hypoxia-induced lung inflammation and vascular remodeling through mtROS-NLRP3 signaling pathway  Acta Pharmacol Sin.  2020  2020 Sep;41(9):1197-1207 
    Cui S, Ni Y, Zhao Y, Li Z, Xiong L, Liu J, Liang X,  Epidermal growth factor receptor-targeted immunomagnetic liposomes for circulating tumor cell enumeration in non-small cell lung cancer treated with epidermal growth factor receptor-tyrosine kinase inhibitors  Lung Cancer  2019  132: 45-53. 
    Xiong L, Li R, Sun J, Lou Y, Zhang W, Bai H, Wang H, Shen J, Jing B, Shi C, Zhong H, Gu A,, Shi J, Fang W, Zhao H, Zhang J, Wang J, Ye J, Han B  Erlotinib as Neoadjuvant Therapy in Stage IIIA (N2) EGFR Mutation-Positive Non-Small Cell Lung Cancer: A Prospective, Single-Arm, Phase II Study  Oncologist  2019  24(2):157-e64. 
    Yan B, Zhang W, Mao XW,  Circular RNA ciRS-7 correlates with advance disease and poor prognosis, and its down-regulation inhibits cells proliferation while induces cells apoptosis in non-small cell lung cancer  Eur Rev Med Pharmacol Sci  2018  22 (24): 8712-8721. 
    Cui S, Dong L, Qian J, Ye L,  Classifying Non-Small Cell Lung Cancer by Status of Programmed Cell Death Ligand 1 and Tumor-Infiltrating Lymphocytes on Tumor Cells  Journal of Cancer  2018  9(1): 129-134. 
    Liu J, Cui S, Pan F, Ni Y, Zhong H, Xiong L, Jin B, Chu T, Gu A,  Feasibility of continuing crizotinib therapy after RECIST-PD in advanced non-small cell lung cancer patients with ALK/ROS-1 mutations  Journal of Cancer  2018  9(10):1863-1869. 
    Wang C, Yin R, Dai J, Gu Y, Cui S, Ma H, Zhang Z, Huang J, Qin N, Jiang T, Geng L, Zhu M, Pu Z, Du F, Wang Y, Yang J, Chen L, Wang Q, Jiang Y, Dong L, Yao Y, Jin G, Hu Z,, Xu L, Shen H  Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients  Nature Communications  2018  9(1):2054. 
    Cui S, Cheng Z, Qin W,  Exosomes as a liquid biopsy for lung cancer  Lung Cancer  2018  116: 46-54. 
    Pan F, Cui S, Wang W, Gu A,  Survival analysis for lung adenosquamous carcinoma patients with brain metastasis  Journal of Cancer  2018  9(20):3707-3712. 
    Cui S, Ye L, Wang H, Chu T, Zhao Y, Gu A, Xiong L, Shi C,  Use of SuperARMS EGFR Mutation Detection Kit to Detect EGFR in Plasma Cell-free DNA of Patients With Lung Adenocarcinoma  Clinical Lung Cancer  2018  19(3): e313-e322. 
    , Su X, Zhang T, Yin X, Zhang M, Fu H, Han H, Sun Y, Dong L, Qian J, Xu Y, Fu X, Gavine PR, Zhou Y, Tian K, Huang J, Shen D, Jiang H, Yao Y, Han B, Gu Y  PD-L1 expression and its relationship with oncogenic drivers in non-small cell lung cancer (NSCLC)  Oncotarget  2017  8(16):26845-26857 
    Cui S,  Factors associated with efficacy of first-generation epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer  Tumour Biology  2017  39(5):1010428317705340 
    Cui S, Zhang W, Xiong L, Pan F, Niu Y, Chu T, Wang H, Zhao Y,  Use of capture-based next-generation sequencing to detect ALK fusion in plasma cell-free DNA of patients with non-small-cell lung cancer  Oncotarget  2017  8(2): 2771-2780 
    Xiong L, Cui S, Ding J, Sun Y, Zhang L, Zhao Y, Gu A, Chu T, Wang H, Zhong H, Ye X, Gu Y, Zhang X, Hu M,  Dynamics of EGFR mutations in plasma recapitulates the clinical response to EGFR-TKIs in NSCLC patients  Oncotarget  2017  8(38): 63846-63856. 
    Cui S, Su X, Dong L, Qian J, Ye L, Zhang T, Fu H, Han H, Huang J, Yao Y, Gu Y,  Programmed cell death ligand 1 protein levels predicted survival of non-small cell lung cancer  Journal of Cancer  2017  8(19):4075-4082. 
    , Huang J, Higgs BW, Hu Z, Xiao Z, Yao X, Conley S, Zhong H, Liu Z, Brohawn P, Shen D, Wu S, Ge X, Jiang Y, Zhao Y, Lou Y, Morehouse C, Zhu W, Sebastian Y, Czapiga M, Oganesyan V, Fu H, Niu Y, Zhang W, Streicher K, Tice D, Zhao H, Zhu M, Xu L, Herbst R, Su X, Gu Y, Li S, Huang L, Gu J, Han B, Jallal B, Shen H, Yao Y  Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer  PLoS Genet  2016  12(4):e1005895 
    Wang B, Zhang J, Song F, Tian M, Shi B, Jiang H, Xu W, Wang H, Zhou M, Pan X, Gu J, Yang S,, Li Z  EGFR Regulates Iron Homeostasis to Promote Cancer Growth through Redistribution of Transferrin Receptor 1  Cancer Letters  2016  381(2):331-340 
    Cui S, Xiong L, Lou Y, Shi H, Gu A, Zhao Y, Chu T, Wang H, Zhang W, Dong L,  Clinical model to predict progression-free survival in EGFR-mutant lung adenocarcinoma patients treated with first-generation EGFR-TKIs  Transl Cancer Res  2016  5(4):476-85 
    Wu X, Liu Z, Chang SC, Fu C, Li W, Jiang H,, Li S  Screening and managing obstructive sleep apnoea in nocturnal heart block patients: an observational study  Respir Res  2016  2016 Feb 16;17:16. 
    Cui S, Zhao Y, Dong L, Gu A, Xiong L, Qian J, Zhang W, Niu Y, Pan F,  Is There a Progression-free Survival Benefit of First-line Crizotinib versus Standard Chemotherapy and Second-line Crizotinib in ALK-positive Advanced Lung Adenocarcinoma? A Retrospective Study of Chinese Patients  Cancer Med  2016  5(6):1013-1021 
    Cui S, Xiong L, Lou Y, Shi H, Gu A, Zhao Y, Chu T, Wang H, Zhang W, Dong L,  Factors that Predict Progression-free Survival in Chinese Lung Adenocarcinoma Patients Treated with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors  J Thorac Dis  2016  8(1):68-78 
    Liu X, Lin Q, Fu C, Liu C, Zhu F, Liu Z, Li S,  Association between XPA Gene rs1800975 Polymorphism and Susceptibility to Lung Cancer: A meta-analysis.   Clin Respir J  2016  2016 Jul 27. doi: 10.1111/crj.12535. 
    崔少华,  肺癌ERCC1基因多态性的转化研究进展  世界临床药物  2015  36(4):232-35 
    张薇,  肺癌术前肺功能评估的意义  世界临床药物  2015  36(4):223-6 
    崔少华,  表皮生长因子受体-酪氨酸激酶抑制剂联合全脑放疗同步治疗肺癌多发脑转移的研究进展  世界临床药物  2015  36(4):227-31 
    崔少华,白皓, 董莉莉, 赵怡卓, 顾爱琴, 张伟, 楼煜清,  肺癌脑转移生存预测因素分析  中国肺癌杂志  2015  18(7): 435-42 
    董莉莉,  基于反馈系统控制优化组合药物技术的应用进展  世界临床药物  2015  36（9）：587-590 
    Cui S, Zhao Y, Gu A, Ge X, Song Y, Zhang W, Lou Y, Dong L, Han B,  Efficacy and tolerability of crizotinib in the treatment of ALK-positive, advanced non-small cell lung cancer in Chinese patients  Med Oncol  2015  32(6):180 
    Zilong liu,, Fen Zhu, Cuiping Fu, Shenyuan Lu, Jing Zhou, Xiaodan Wu, Chunxue Bai, Shanqun Li  Chronic intermittent hypoxia and the expression of orexin and its receptors in the brains of rats  Sleep and Biology Rhythms  2014  12:22-9 
    Fu C, Liu Z, Zhu F, Li S,  A meta-analysis: is low-dose computed tomography a superior method for risky lung cancers screening population?  Clin Respir J  2014  doi: 10.1111/crj.12222. [Epub ahead of print] 
    Zhu F, Wang W, Hou Y, Shi J, Liu Z, He D, Bai C, Li S,  MAML2 rearrangement in primary pulmonary mucoepidermoid carcinoma and the correlation with FLT1 expression  PLoS One  2014  9(4):e94399 
    崔少华,  非小细胞肺癌ERCC1表达的转化研究现状  中国肺癌杂志  2014  17(5):428-32 
    , Zhu W, Streicher K, Morehouse C, Brohawn P, Ge X, Dong Z, Yin X, Zhu G, Gu Y, Ranade K, Higgs BW, Yao Y1, Huang J  Increased IR-A/IR-B ratio in non-small cell lung cancers associates with lower epithelial-mesenchymal transition signature and longer survival in squamous cell lung carcinoma  BMC Cancer  2014  14:131 
    葛晓晓,  肺癌与TTF-1分子标志物研究进展  中国肺癌杂志  2014  17(6):491-5 
    Liu YR, Zhu W, Zhang JL, Huang JQ, Zhao YZ, Zhang W, Han BH, Yao YH,, Li SQ  The evaluation of efficacy and safety of sunitinib on EGFR-TKI pretreated advanced non-small cell lung cancer patients in China  Clin Respir J  2014  8(2):206-12 
    Chu T, Teng J,, Zhong H, Han B  Lung cancer-derived Dickkopf1 is associated with bone metastasis and the mechanism involves the inhibition of osteoblast differentiation  Biochem Biophys Res Commun  2014  443(3):962-8 
    Li S, Liu Z, Zhu F, Fan X, Wu X, Zhao H,  Curcumin lowers erlotinib resistance in small cell lung carcinoma cells with mutated EGF receptor  Oncol Res  2013  21(3):137-44 
    , Huang J, Morehouse C, Zhu W, Korolevich S, Sui D, Ge X, Lehmann K, Liu Z, Kiefer C, Czapiga M, Su X, Brohawn P, Gu Y, Higgs BW, Yao Y  Low frequency KRAS mutations in colorectal cancer patients and the presence of multiple mutations in oncogenic drivers in non-small cell lung cancer patients  Cancer Genet  2013  206(9-10):330-9 
    Zhang W, Yan B,  Predictive effect of XRCC3 Thr241Met polymorphism on platinum-based chemotherapy in lung cancer patients: meta-analysis  Tumour Biol  2013  34(6):3989-93 
    Zhu F, Liu Z, Hou Y, He D, Ge X, Bai C, Jiang L*,  Primary salivary gland-type lung cancer: clinicopathological analysis of 88 cases from China  J Thorac Oncol  2013  8(12):1578-84 
    牛艳洁,江银玲,许长江,王向迎,刘友如,赵珩,韩宝惠,  代谢组学方法分析肺癌患者血清和尿液小分子代谢产物的初步研究  中国肺癌杂志  2012  15(4):195-201 
    王向迎,刘友如,牛艳洁,江银玲,韩宝惠,  非小细胞肺癌EGFR基因突变检测技术进展  国际呼吸杂志  2012  32(10):793-7 
    葛晓晓,澹台冀澂,刘友如,赵珩,  TTF-1在I期非小细胞肺癌中的表达与预后  中华胸心血管外科杂志  2012  28(11):662-4 
    王向迎,刘友如,高志强,江银玲,韩宝惠,  晚期肺腺癌EGFR-TKIs对后续培美曲赛化疗的影响  中国肺癌杂志  2012  15(5):294-8 
    卢芳,陈仲林,顾广羽,韩宝惠,李颖则,  对加强药物临床试验院内质量管理的探讨  中国药房  2011  22(45):4235-7 
    江银铃,赵珩,牛艳洁,韩宝惠,  胸内结节病的临床特征及治疗分析  上海交通大学学报（医学报）  2011  31(3):353-6 
    刘友如,江银铃,高志强,王向迎,韩宝惠,  培美曲赛单药与培美曲赛联合奥沙利铂用于Ⅳ期肺腺癌挽救性治疗的比较  中国肺癌杂志  2011  14(9):704-9 
    潘峰,  非小细胞肺癌靶向治疗的最新进展  中国临床医学  2011  18(6):892-6 
    夏金晶,,张杰,苗茜,忻宇,钟润波,赵怡卓,韩宝惠  原发性肺淋巴上皮瘤样癌21例手术患者临床分析  中国肺癌杂志  2009  12(11):1169-73 
    Gu P,Zhao YZ,,Zhang W,Xin Y,Han BH  Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a systematic review and meta-analysis  Eur J Cancer  2009  45(8):1389-96 
    Guo Z,Li X,,Xu LF  Extracorporeal membrane oxygenation for the management of respiratory failure caused by diffuse alveolar hemorrhage  J Extra Cprpor Technol  2009  41(1):37-40 
    苗茜,  小细胞肺癌二线治疗进展  中国肺癌杂志  2008  11(4):591-4 
    苗茜,,牛艳洁,忻宇,赵怡卓,沈洁,卢芳,韩宝惠  97例小细胞肺癌预后的多因素分析  中国癌症杂志  2008  18(10):765-9 
    Zhong H,Chen JH,Li SQ,,Li X,Han BH   Extracorporeal membrane oxygenation for pulmonary hemorrhage in microscopic polyangiitis  Chin Med J(Engl)  2008  121(24):2622-3