- 基本信息
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导师姓名：
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龚伟
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学科代码：
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100210
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性别：
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男
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学科名称：
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外科学
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培养单位：
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附属新华医院
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三级学科
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普外
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导师类型：
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博士生导师
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专业领域名称：
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外科学 专业学位
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联系方式：
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13651819806@163.com
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专业领域代码：
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105111
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邮编：
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200092
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邮箱地址：
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13651819806@163.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中华医学会外科学分会全国中青年委员
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中华实验外科杂志专家委员会委员
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中国医师协会胆道外科委员会委员
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上海市医学会外科学会胆道学组委员
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Journal of Digestive Disease, PlosOne等杂志审稿专家
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中华肝胆外科杂志通讯编委
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国家自然基金评议专家
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中华医学会外科学分会胆道学组委员
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- 科研项目
| 8217101747 | PLA2G16/GPD2-Wnt/β-catenin正反馈环路对胆囊癌增殖、转移及铁死亡的功能和机制研究 | 国家自然基金 |
2022-01~2025-12
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55万元
| 课题负责人 |
| YG2022ZD009 | 新型光偶联水凝胶在肝胆胰外科中的应用研究 | 上海交通大学“交大之星”计划医工交叉研究基金重点项目 |
2022-01~2024-12
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100万元
| 课题负责人 |
| 21XHDB10 | 胆道恶性肿瘤多组学全息数据库的建立 | 上海交通大学医学院附属新华医院院级临床支撑培育项目 |
2022-01~2023-12
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30万元
| 课题负责人 |
| 81974371 | IMP3介导的lncRNA-LEMD1促进胆囊癌细胞侵袭转移的功能及机制研究 | 国家自然基金 |
2020-01~2023-12
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55万元
| 课题负责人 |
| TT-00420 | 多激酶抑制剂TT-00420的临床与多中心篮式实验 | 国家重大科技专项子项目 |
2019-01~2020-12
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41.6万元
| 课题负责人 |
| 58949349 | MALAT1通过负调控 miR-31促进胆囊癌发生发展的分子机制研究 | 国家自然基金 |
2017-01~2020-01
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56万元
| 课题负责人 |
| 20151001 | 上海交通大学医学院高原高峰计划 | 上海交大医学院 |
2015-10~2018-10
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100万元
| 课题负责人 |
| 124119a0600 | 胆囊癌中微小RNA（miRNA）对化疗敏感性调控的研究 | 上海市科委 |
2012-10~2015-09
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20万元
| 课题负责人 |
| 2009064 | 抑癌基因ING1在表观遗传学调控中的作用 | 上海市卫生局 |
2010-12~2012-12
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4万元
| 课题负责人 |
| 81172026 | 胆囊癌长链非编码RNA的功能及其相关分子机制研究 | 国家自然基金 |
2010-12~2012-12
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28万元
| 课题参与人 |
| 10410700100 | 粘液瘤病毒对胃癌的治疗作用及其机制研究 | 上海市科委国际合作 |
2010-06~2012-06
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20万元
| 课题负责人 |
- 学术论文
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Yang Z, Wu Z, Xiong Y, Liu S, Cai C, Shao Z, Zhu Y, Song X, Shen W, Wang X, Wu X,
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Successful conversion surgery for locally advanced gallbladder cancer after gemcitabine and nab-paclitaxel chemotherapy
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Frontiers in Oncology
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2022
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Aug 16;12:977963
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Liu S, Li H, Zhu Y, Ma X, Shao Z, Yang Z, Cai C, Wu Z, Li M,, Wu X.
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LncRNA MNX1-AS1 sustains inactivation of Hippo pathway through a positive feedback loop with USP16/IGF2BP3 axis in gallbladder cancer
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Cancer Letters
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2022
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2022 Oct 28;547:215862.
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Shilei Liu, Bingfeng Chu, Chen Cai, Xiangsong Wu, Wenyan Yao, Ziyou Wu, Ziyi Yang, Fengnan Li, Yingbin Liu, Ping Dong,
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DGCR5 Promotes GallbladderCancer by Sponging MiR-3619-5p via MEK/ERK1/2 and JNK/p38 MAPK Pathways
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J Cancer.
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2020
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2020; 11(18): 5466–5477.
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Shilei Liu, Fengnan Li, Lijia Pan, Ziyi Yang, Yijun Shu, Wenjie Lv, Ping Dong,
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BRD4 inhibitor and histone deacetylase inhibitor synergistically inhibit the proliferation of gallbladder cancer in vitro and in vivo
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Cancer Science
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2019
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00:1-14
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Fei Zhang, Qiang Ma1,Zihang Xu3, Haibin Liang,Huaifeng Li, Yuanyuan Ye, Shanshan Xiang,Yijian Zhang, Lin Jiang, Yunping Hu, Zheng Wang, Xuefeng Wang, Yong Zhang,,Yingbin Liu1
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Dihydroartemisinin inhibits TCTPdependent metastasis in gallbladder cancer
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Journal of Experimental & Clinical Cancer Research
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2017
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DOI 10.1186/s13046-017-0531-3
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Fa-Yong Ke, Xiang-Song Wu, Yong Zhang, Hong-Cheng Zhang, Ming-Zhe Weng, Ying-Bin Liu, Christopher Wolfgang,
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Comparison of postoperative complications between internal and external pancreatic duct stenting during pancreaticoduodenectomy: a meta-analysis.
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Chinese Jouranl of Cancer Research
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2015
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27(4):397-407
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Hongchen Zhang, Jian Zhu, Fayong Ke, Mingzhe Weng, Xiangsong Wu, Maolan Li, Zhiwei Quan, Yingbin Liu, Yong Zhang,
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Radiological Imaging for Assessing the Respectability of Hilar Cholangiocarcinoma: A Systematic Review and Meta-Analysis
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Biomed Research International
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2015
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2015
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Mingzhe Weng,, Mingzhe Ma, Bingfeng Chu, Yiyu Qin, Mingdi Zhang, Xueqing Lun,Grant McFadden, Peter Forsyth, Yong Yang and Zhiwei Quan
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Targeting gallbladder cancer: oncolytic virotherapy with myxoma virus is enhanced by rapamycin in vitro and further improved by hyaluronan in vivo.
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Molecular Cancer
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2014
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13(1):1-15
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,刘颖斌
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胰腺囊性占位的诊断和处理
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肝胆外科杂志
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2013
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21(4):253-255
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p33ING1b蛋白在胆囊癌中表达的研究
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肝胆外科杂志
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2011
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12:541-457.
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Zhou D, Zhang Y,, Mohamed SO, Ogbomo H, Wang X, Liu Y, Quan Z.
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Are Helicobacter pylori and other Helicobacter species infection asso ciated with human biliary lithiasis? A meta-analysis.
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Plos one
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2011
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6(11):e27390.
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胰腺假性囊肿治疗的选择
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肝胆外科杂志
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2011
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42:49-250
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先天性胆总管囊肿与胆管癌
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肝胆外科杂志
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2010
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5:333-334
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, Russell M, Suzuki K, Riabowol K.
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Subcellular Targeting of p33ING1b by Phosphorylation-Dependent 14-3-3 Binding Regulates p21WAF1 Ex pressions.
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Mol Cell Bio.
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2006
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26(8):2947-54.
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Russell M, Berardi P,, Riabowol K.
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Grow-ING, Age-ING and Di e-ING: ING proteins link cancer, senescence and apoptosis.
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Experimental Cell Research.
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2006
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312:6951–6961
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, Qin YY, Li SG, Quan ZW, Li JY, Zhuang PY, Wan ZW. Zhonghua Yi Xue Za Zhi.
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Somatostatin enhanced anti-tumor effect of doxorubicin on gallbladder cancer cells through the regulation of intracellular drug co ncentration.
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中华医学杂志
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19;90(38):2718-22.
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Chivers JE,, King EM, Seybold J, Mak JC, Donnelly L E, Holde n NS, Newton R.
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Analysis of the dissociated steroid RU24858 does not excl ude a role for inducible genes in the anti-inflammatory actions of glucoc orticoids.
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Mol Pharmacol.
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70(6):2084-95.
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Qin Y, Zhang S,, Li J, Jia J, Quan Z.
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Adenovirus-mediated gene transfer of TFPI-2 inhibits gallbladder carcinoma growth in vitro and in vivo.
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Cancer Sci
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10：1349-7006
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Mingzhe Weng., Yong Zhang., Di Zhou, Yong Yang, Zhaohui Tang, Mingning Zhao, Zhiwei Quan*,
Wei Gong(龚伟)*
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Radiofrequency Ablation versus Resection for Colorectal
Cancer Liver Metastases: A Meta-Analysis
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Plos One
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7(9): e45493-45501
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Jia J, Li S,, Ding J, Fang C, Quan Z.
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mda-7/IL-24 induces a poptosis in human GBC-SD gallbladder carcinoma cells via mitochondrial a poptotic pathway.
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Oncol Rep.
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25(1):195-201.
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, W(龚伟), Suzuki K, Russell M, Riabowol K.
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Function of the ING family of PHD proteins in cancer.
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Int J Biochem Cell Biol.
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37(5):1054-1065.
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Suzuki K, Boland D,, Riabowol K.
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Adenovirus-mediated gene transfer of TFPI-Domain recognition of the ING1 tumor suppressor by a panel of monoclonal antibodies.
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Hybridoma
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30(3):239-45
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