- 基本信息
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导师姓名：
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金玮
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学科代码：
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100201
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性别：
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女
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学科名称：
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内科学
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培养单位：
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附属瑞金医院
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三级学科
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心血管病
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导师类型：
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博士生导师
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专业领域名称：
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内科学 专业学位
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联系方式：
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上海交通大学医学院附属瑞金医院心脏科
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专业领域代码：
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105101
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邮编：
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200025
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邮箱地址：
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jinwei_ivy@126.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中国心衰中心联盟秘书长兼上海心衰中心副主席
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上海市医学会心血管病第十一届委员会，心衰学组副组长
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上海市医学会慢病管理第二届委员会，副主任委员
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中华医学会/中国医师协会心血管病分会心力衰竭学组，全国委员
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中国医疗保健国际交流促进会精准心血管病分会，常务委员
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国家心血管病中心心肌病专科联盟专家委员会工作组，副组长
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健康中国研究中心精准心血管病学专家委员会，副主任委员
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首批中国罕见病联盟ATTR心肌病诊疗中心，瑞金医院负责人
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中华医学会心血管病学分会首批“中国心衰中心示范基地”瑞金医院负责人
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中华医学会心血管病学分会精准心血管病学学组合作示范基地“瑞金医院心力衰竭/心肌病精准诊疗中心”负责人
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全国肥厚型心肌病联合诊疗首席专家
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《中华心血管病杂志》，第九届编辑委员会，通讯编委
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《中华心力衰竭和心肌病杂志（中英文）》，第一届编辑委员会，委员
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《中国分子心脏病学杂志》，第五届编辑委员会，编委
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- 科研项目
| 82270404 | 转酮醇酶核转位上调心肌细胞糖酵解代谢在心室重构中的作用机制研究 | 国家自然科学基金面上项目 |
2023-01~2026-12
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52万元
| 课题负责人 |
| 21XD1402100 | 心力衰竭中肠道菌代谢物ImP损伤心功能的作用及机制研究 | 上海市科学技术委员会 |
2021-09~2024-09
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40万元
| 课题负责人 |
| 201409005100 | 转甲状腺素蛋白淀粉样变心肌病人源化小鼠模型构建 | 上海市科学技术委员会 |
2020-06~2024-06
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20万元
| 课题负责人 |
| 81970337 | Chromogranin A-Catestatin失衡与再平衡 在射血分数降低型心力衰竭中的调控及机制探索 | 国家自然科学基金•面上项目 |
2020-01~2023-12
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55万元
| 课题负责人 |
| TM201802 | 儿茶酚抑素Catestatin作为心衰转归生物标志物的转化研究 | 转化医学协同创新中心合作研究项目 |
2018-08~2020-07
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15万元
| 课题负责人 |
| 17140902500 | 射血分数保留型心力衰竭小鼠模型构建 | 上海市科学技术委员会 |
2017-07~2019-06
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30万元
| 课题负责人 |
| 81670266 | Dectin-2/CCTη信号轴在心肌梗死后心室重构中的作用及机制探究 | 国家自然科学基金•面上项目 |
2017-01~2020-12
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65万元
| 课题负责人 |
| XBR2013100 | 第二批第一轮上海市卫生系统优秀学科带头人（简称：新百人计划） | 上海市卫生和计划生育委员会 |
2014-01~2016-12
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45万元
| 课题负责人 |
| 81370397 | Catestatin 蛋白肽段抑制动脉粥样硬化的作用及机制研究 | 国家自然科学基金•面上项目 |
2014-01~2017-12
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75万元
| 课题负责人 |
| 81070177 | 中国汉族人群冠心病相关拷贝数变异的鉴定 | 国家自然科学基金•面上项目 |
2011-01~2013-12
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35万元
| 课题负责人 |
| 06QA14033 | 从基因通路途径探索早发冠心病的分子遗传机制 | 上海市科委•启明星 |
2006-10~2008-09
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10万元
| 课题负责人 |
| 30500576 | 内源性抗氧化体系基因变异及SNPs单倍型与冠心病 | 国家自然科学基金•面上项目 |
2006-01~2008-12
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25万元
| 课题负责人 |
- 学术论文
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Yunjing Shi, Hao Zhang, Zeping Qiu, Yanjia Chen, Xiuxiu Su, Huihui Chi, Tienan Feng, Yue Sun, Honglei Liu, Xiaobing Cheng, Junna Ye, Hui Shi, Qiongyi Hu, Zhuochao Zhou, Jianfen Meng, Jialin Teng, Chengde Yang, Yutong Su,
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Value of the HFA-PEFF diagnostic algorithms for heart failure with preserved ejection fraction to the inflammatory myopathy population
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Arthritis Res Ther.
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2023
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Aug 4;25(1):141.
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Fanyi Huang, Yawei Du, Yanjia Chen, Zeping Qiu, Zhiyan Wang, Yingze Fan, Yunjing Shi, Zhuojin Li, Ke Yang, Wenguo Cui,
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Cellular Membrane-Engineered Nanovesicles as Three-Stage Booster to Target Lesion Core.
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Adv Mater.
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2023
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Aug 17:e2302801.
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Sha Hua, Bomin Lv, Zeping Qiu, Zhuojin Li, Zhiyan Wang, Yanjia Chen, Yanxin Han, KL Tucker, Hao Wu,
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Microbial metabolites in chronic heart failure and its common comorbidities
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EMBO Mol Med.
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2023
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May 8:e16928.
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Yunjing Shi, Zeping Qiu, Jing Yu, Zhuojin Li, Sha Hua, Yanjia Chen, Xiaosong Chen, Kunwei Shen,
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Association between insulin resistance and cardiac remodeling in HER2-positive breast cancer patients: a real-world study
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BMC Cancer
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2023
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615 (2023)
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Zeping Qiu, Yingze Fan, Zhiyan Wang, Fanyi Huang, Zhuojin Li, Zhihong Sun, Sha Hua,, Yanjia Chen
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Catestatin Protects Against Diastolic Dysfunction by Attenuating Mitochondrial Reactive Oxygen Species Generation
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J Am Heart Assoc.
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2023
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Apr 29:e029470.
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Zhiyan Wang, Zeping Qiu, Sha Hua, Wenbo Yang, Yanjia Chen, Fanyi Huang, Yingze Fan, Lingfeng Tong, Tianle Xu, Xuemei Tong, Ke Yang,
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Nuclear Tkt promotes ischemic heart failure via the cleaved Parp1/Aif axis.
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Basic Res Cardiol.
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2022
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117(1):18.
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Yulong Sun, Yanxin Han, Yannong Dou, Xinqi Gong, Haimang Wang, Xiaoyu Yu, Qiang Wang, Yixin Wang, Yue Dai, Fangfu Ye,, Hongyu Zhang
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Polymeric coating lubricates nanocontainers to escape macrophage uptake for bioreceptor recognition
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Bioact Mater.
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2022
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14:120-133.
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Fanyi Huang, Lingyu Sun, Cheng Zhao, Zeping Qiu, Yuanjin Zhao,
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Protein microcapsules integrated hierarchical scaffolds for local treatment of acute myocardial infarction model
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Appl Mater Today.
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2021
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22:100901
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Yanjia Chen, Zeping Qiu, Jie Jiang, Xiuxiu Su, Fanyi Huang, Jing Tang,
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Outcomes of Spironolactone Withdrawal in Dilated Cardiomyopathy With Improved Ejection Fraction
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Front Cardiovasc Med.
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2021
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8:725399.
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Zeping Qiu, Jingwen Zhao, Fanyi Huang, Luhan Bao, Yanjia Chen, Ke Yang, Wenguo Cui,
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Myocardial fibrosis reversion via rhACE2-electrospun fibrous patch for ventricular remodeling prevention
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NPJ Regen Med.
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2021
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6(1):44.
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Zhuochao Zhou, Junna Ye, Jialin Teng, Honglei Liu, Xiaobing Cheng,Yue Sun, Yutong Su, Huihui Chi, Fan Wang, ChengdeYang,
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Clinical characteristics of infective endocarditis in patients with antineutrophil cytoplasmic antibody or antiphospholipid antibody: a retrospective study in Shanghai.
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BMJ OPEN
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2020
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10(2): e31512.
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Wenbo Yang, Andi Zhang, Yanxin Han, Xiuxiu Su, Yanjia Chen, Weilin Zhao, Ke Yang,
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Cyclin dependent kinase inhibitor-2b controls fibrosis and functional changes in ischemia-induced heart failure via the BMI1-p15-Rb signaling pathway.
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Canadian journal of cardiology
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2020
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Epub ahead of print.
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Wenbo Yang, Xuemei Wei, Xiuxiu Su, Yan Shen,, Yuehua Fang
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Depletion of β3-adrenergic receptor induces left ventricular diastolic dysfunction via potential regulation of energy metabolism and cardiac contraction.
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Gene
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2019
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697:1-10.
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Yanjia Chen, Xiaoqun Wang, Chendie Yang, Xiuxiu Su, Wenbo Yang, Yang Dai, Hui Han, Jie Jiang, Lin Lu, Haibo Wang, Qiujing Chen,
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Decreased circulating catestatin levels are associated with coronary artery disease: the emerging anti-inflammatory role.
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Atherosclerosis
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2019
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281:78-88.
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Wenbo Yang, Yanxin Han, Chendie Yang, Yanjia Chen, Weilin Zhao, Xiuxiu Su, Ke Yang,
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MicroRNA-19b-1 reverses ischaemia-induced heart failure by inhibiting cardiomyocyte apoptosis and targeting Bcl2 l11/BIM.
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Heart Vessels
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2019
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34(7): 1221-1229.
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Chendie Yang, Ying Shen, Lin Lu, Fenghua Ding, Zhenkun Yang, Ruiyan Zhang, Weifeng Shen,, Xiaoqun Wang
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Insulin resistance and dysglycemia are associated with left ventricular remodeling after myocardial infarction in non-diabetic patients.
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Cardiovascular Diabetology
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2019
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18(1).
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Yixuan Shang, Zhuoyue Chen, Fanfan Fu, Lingyu Sun, Changmin Shao,, Hong Liu, Yuanjin Zhao
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Cardiomyocyte-Driven Structural Color Actuation in Anisotropic Inverse Opals.
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ACS Nano
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2019
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13(1):796-802.
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Wenbo Yang, Zhijun Wu, Ke Yang, Yanxin Han, Yanjia Chen, Weilin Zhao, Fanyi Huang, Yao Jin,
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BMI1 Promotes Cardiac Fibrosis in Ischemia-Induced Heart Failure via the PTEN-PI3K/AKT-mTOR Signaling Pathway.
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American Journal of Physiology-Heart and Circulatory Physiology
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2019
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316(1):H61-H69.
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Zhijun Wu, Haihui Sheng, Xiuxiu Su, Xiang Gao, Lin Lu,
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Mediating Effect of Diabetes Mellitus on the Association Between Chromosome 9p21.3 Locus and Myocardial Infarction Risk: A Case-Control Study in Shanghai, China.
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Front Endocrinol
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2018
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9:362.
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Zhijun Wu,Xiuxiu Su,Haihui Sheng,Yanjia Chen, Xiang Gao,Le Bao,
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Conditional Inference Tree for Multiple Gene-Environment Interactions on Myocardial Infarction Among Chinese Men.
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Arch Med Res
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2017
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48(6):546-552
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Jie Liu#, Hongxin Zhang, Zhijun Wu, Jing Tang, Xiuxiu Su, Yanjia Chen,
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Association between ApoE gene and myocardial bridge in Chinese Han population: A case-control study.
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Int J Clin Exp Pathol
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2016
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9(4):4587-4594
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Hui Han, Yanjia Chen, Zhengbin Zhu1, Xiuxiu Su1, Jingwei Ni1, Run Du1, Ruiyan Zhang,
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p-Cresyl sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascular smooth muscle cells.
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Front. Med.
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2016
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10(3):320-329.
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Yanjia Chen, Hui Han, Xiaoxiang Yan, Fenghua Ding, Xiuxiu Su, Haibo Wang,Qiujing Chen, Lin Lu, Ruiyan Zhang,
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Tetranectin as a Potential Biomarker for Stable Coronary Artery Disease.
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Scientific Reports
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2015
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5:17632-17639.
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Zhijun Wu, Haihui Sheng, Yanjia Chen, Jing Tang, Yan Liu, Qiujing Chen, Lin Lu,
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Copy number variation of the Lipoprotein(a) (LPA) gene is associated with coronary artery disease in a southern Han Chinese population.
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Int J Clin Exp Med.
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2014
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7(10):3669-3677.
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Zhijun Wu, Min Xu, Haihui Sheng, Yuqing Lou, Xiuxiu Su, Yanjia Chen, Lin Lu, Yan Liu,
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Association of natriuretic peptide polymorphisms with left ventricular dysfunction in southern Han Chinese coronary artery disease patients.
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Int J Clin Exp Pathol.
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2014
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7(10):7148-7157.
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Zhijun Wu, Yuqing Lou, Xiaochun Qiu, Yan Liu, Lin Lu, Qiujing Chen,
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Association of cholesteryl ester transfer protein (CETP) gene polymorphism, high density lipoprotein cholesterol and risk of coronary artery disease: a meta-analysis using a Mendelian randomization approach.
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BMC Medical Genetics
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2014
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15(1):118-120.
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Wenquan Niu, Yan Liu, Yue Qi, Zhijun Wu, Dingliang Zhu,
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Association of interleukin-6 circulating levels with coronary artery disease: a meta-analysis implementing mendelian randomization approach.
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Int J Cardiol.
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2012
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157(1):243-252.
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Yan Liu, Wenquan Niu, Zhijun Wu, Xiuxiu Su, Qiujin Chen, Lin Lu,
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Variants in exon 11 of MEF2A gene and coronary artery disease: evidence from a case-control study, systematic review, and meta-analysis.
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PLoS ONE
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2012
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7(2):e31406.
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, Xiuxiu Su, Min Xu , Yan Liu, Jingyi Shi, Lin Lu, Wenquan Niu.
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Interactive Association of Five Candidate Polymorphisms in Apelin/APJ Pathway with Coronary Artery Disease among Chinese Hypertensive Patients.
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PLoS ONE
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2012
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7(12):511-23.
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Wenquan Niu, Yan Liu, Yue Qi, Zhijun Wu, Dingliang Zhu, Wei Jin
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Association of interleukin-6 circulating levels with coronary artery disease: a meta-analysis implementing mendelian randomization approach
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International Journal of Cardiology
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2012
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157(2): 243-252.
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Wenquan Niu,Yue Qi,Zhijun Wu,Yan Liu,Dingliang Zhu,
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A meta-analysis of receptor for advanced glycation endproducts gene: four well-evaluated polymorphisms with diabetes mellitus.
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Mol Cell Endocrinol.
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2012
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358(1):9-17.
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刘艳,陆林,吴志俊,陈秋静,沈卫峰,
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肿瘤坏死因子a基因与上海地区汉族人群冠心病发病风险的关系
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上海交通大学学报(医学版)
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2011
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31(5):592-597.
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Yan Liu, Haihui Sheng, Lin Lu, Zhijun Wu, Qiujin Chen, Huasheng Xiao,
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Haplotype-based association of four lymphotoxin-alpha gene polymorphisms with the risk of coronary artery disease in Han Chinese
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Tohoku J.Exp.Med.
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2011
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224(2):119-125.
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潘佳君,石川,刘艳,陈秋静,陆林,
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发热诱导的Brugada波与SCN5A基因变异的研究
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内科理论与实践
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2010
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5(2):173-176.
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,吴志俊,陆林,陈秋静,刘艳
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肾素基因启动子区单倍型与原发性高血压的关系
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诊断学理论与实践
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2010
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9(2):166-169.
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刘艳,,陆林,陈秋静,沈卫峰
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肿瘤坏死因子-α基因启动子区域多态与冠心病的相关性
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诊断学理论与实践
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2009
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8(5):506-509.
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刘艳,,陆林, 陈秋静,沈卫峰
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肿瘤坏死因子a基因启动子区域一1031T／C多态与不稳定性心绞痛的相关性
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中华医学遗传学杂志
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2009
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26(5):571-573.
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刘艳,,陆林, 陈秋静,沈卫峰
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肿瘤坏死因子a基因启动子区域一1031T／C多态与不稳定性心绞痛的相关性
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中华医学遗传学杂志
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2009
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26(5):571-573.
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石川,,王玲洁,璩斌,张凤如
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急性心肌梗死合并双下肢动脉栓塞1例伴遗传易感性分析
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内科理论与实践
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2009
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4(3):200-204.
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石川,,邓钰蕾,季旻晔,张凤如
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窦性静止合并癫痫一例报道
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上海交通大学学报(医学版)
|
2009
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29(3):363-364.
|
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刘艳,,陆林,陈秋静,沈卫峰
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肿瘤坏死因子β基因A80C多态与原发性高血压
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内科理论与实践
|
2009
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4(2):121-124.
|
|
吴志俊,
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拷贝数变异：基因组多样性的新形式
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遗传
|
2009
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31(4): 339-47.
|
|
吴志俊,,陆国平
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心肌梗死易感基因:高通量研究的新进展
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国际心血管杂志
|
2008
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35(2):65-68.
|
|
潘佳君,,吕安康
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贫血与急性冠脉综合征的关系
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国际心血管杂志
|
2008
|
35(3):143-146.
|
|
刘艳,沈卫峰,,等
|
男性早发冠心病与血管紧张素原基因启动子区域-217G/A和-152G/A多态
|
内科理论与实践
|
2007
|
2(3):168-171.
|
|
Li Y, Zhang D,, Shao C, Yan P, Xu C, Sheng H, Liu Y, Yu J, Xie Y, Zhao Y, Lu D, Nebert DW, Harrison DC, Huang W, Jin L
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Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin
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J Clin Invest
|
2006
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116(2):506-511.
|
|
,盛海辉,刘艳,等
|
诱导型一氧化氮合酶基因启动子区微卫星多态与急性冠状动脉综合征
|
诊断学理论与实践
|
2006
|
5(3):214-216.
|
|
,沈卫峰,刘艳,等
|
肾素基因单核苷酸多态与心肌梗死的关系
|
上海第二医科大学学报
|
2005
|
25(8):768-771.
|
|
刘艳,,盛海辉,等
|
血管紧张素原基因核心启动子区域的单核苷酸多态与冠心病的关系
|
临床心血管病杂志
|
2005
|
21(1):43-45.
|
|
,刘艳,盛海晖,等
|
AT1基因启动子区单核苷酸多态与原发性高血压合并冠心病相关
|
诊断学理论与实践
|
2005
|
4(1):44-88.
|
|
刘艳,陶蓉,,等
|
白细胞介素-1a基因启动子区域C-889T多态与冠心病的相关性
|
诊断学理论与实践
|
2005
|
4(2):130-132.
|
|
, Liu Y, Sheng HH,et al
|
Single nucleotide polymorphisms in promoter of angiotensin II type 1 receptor gene associated with essential hypertension and coronary heart disease in Chinese population
|
Acta Pharmacol Sin
|
2003
|
24(11):1083-1088.
|
|