- 基本信息
导师姓名:
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陈楠
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学科代码:
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100201
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性别:
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女
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学科名称:
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内科学
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培养单位:
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附属瑞金医院
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三级学科
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肾病
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导师类型:
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博士生导师
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专业领域名称:
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内科学 专业学位
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联系方式:
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专业领域代码:
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105101
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邮编:
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邮箱地址:
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chen-nan@medmail.com.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
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editorial board member of American Journal of Kidney Disease
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上海市肾脏病医师协会副会长
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ISN East Asian Committee member
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上海市医学会罕见病分会副主任委员
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亚太地区CKD防治委员会委员
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中华医学会肾脏病分会常委
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中国医师协会肾脏病医师分会副会长
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editorial board member of Nephrology Dialysis Transplantation
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- 科研项目
2013SY017 | 系统性血管炎标准化筛查与诊断在基层医院的应用 | 上海卫生系统先进适宜技术推广项目 |
2014-01~2016-01
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50万元
| 课题负责人 |
13430720800 | 联合应用多种内源性标记物建立准确性更高的肾小球滤过率评估公式 | 上海市科学技术委员会国际合作项目 |
2013-01~2016-01
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30万元
| 课题负责人 |
2012CB517604 | 常见肾小球疾病发病机制及其早期诊断(肾小球损伤的遗传学研究) | 国家重点基础研究发展计划(973计划) |
2012-01~2015-12
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630万元
| 课题负责人 |
2011BAI10B06 | 肾脏疾病的防治与国产血液净化产品研发及临床应用评价(高血压肾损害及缺血性肾脏病的研究) | 十二五攻关项目 |
2012-01~2016-12
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288万元
| 课题负责人 |
201002010 | 泌尿系统重大疾病的防治研究 | 卫生行业科研专项项目 |
2011-01~2013-12
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122万元
| 课题负责人 |
11DZ1950307 | 法布雷病研究、诊治规范 | 上海市科委基金 |
2011-01~2014-12
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18万元
| 课题负责人 |
81070568 | 中国汉族人家族性局灶节段肾小球硬化症致病基因定位及功能研究 | 国家自然科学基金 |
2011-01~2013-12
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30万元
| 课题负责人 |
08dz1900502 | 慢性肾脏病的筛查及生物学标志物的研究 | 上海市科学技术委员会科研计划项目 |
2009-01~2011-12
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251万元
| 课题负责人 |
| Clinical and Basic Study on the Fabry Disease | Genzyme 合作基金 |
2008-06~2011-05
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18万元
| 课题负责人 |
| Valsartan联合钙三醇干预肾小管间质纤维化的研究 | 诺华科研基金 |
2008-01~2011-12
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10万元
| 课题负责人 |
07JC14037 | 慢性肾脏病分子标识物研究及其应用探讨 | 上海市科委重点项目 |
2007-11~2009-10
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30万元
| 课题负责人 |
30670814 | 特异性阻断IgG-FcγRIIa/IIIb相互作用的新型短肽研究及其在原发性小血管炎中的保护作用 | 国家自然基金委,面上项目 |
2007-01~2009-12
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27万元
| 课题负责人 |
LJ06037 | 遗传性肾脏疾病的筛查和诊断体系的建立及相关基因研究 | 上海市卫生局,医学领军人才 |
2006-01~2010-12
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50万元
| 课题负责人 |
- 学术论文
Xu T, Xie J, Zong X, Wang W, Ren H,
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Pulse Wave Velocity: A Valuable Predictor for Cardio-Cerebrovascular Disease and Death in PD Patients
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Blood Purif
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2015
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40(3):203-8.
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Chen XN, Chen ZJ, Ma XB, Ding B, Ling HW, Shi ZW,
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Aortic Artery and Cardiac Valve Calcification are Associated with Mortality in Chinese Hemodialysis Patients: A 3.5 Years Follow-up.
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Chin Med J (Engl)
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2015
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128(20):2764-2771.
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Zhang C, Ren H, Shen P, Xu Y, Zhang W, Wang W, Li X, Ma Y,
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Clinical evaluation of Chinese patients with primary distal renal tubular acidosis.
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Intern Med.
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2015
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54(7):725-30.
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Tong J, Xie J, Ren H, Liu J, Zhang W, Wei C, Xu J, Zhang W, Li X, Wang W, Lv D, He JC,
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Comparison of Glomerular Transcriptome Profiles of Adult-Onset Steroid Sensitive Focal Segmental Glomerulosclerosis and Minimal Change Disease.
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PLoS One
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2015
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10(11):e0140453
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Zhang W, Wen D, Zou YF, Shen PY, Xu YW, Shi H, Xu J, Chen XN,
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One-year survival and renal function recovery of acute kidney injury patients with chronic heart failure.
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Cardiorenal Med
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2015
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5(1):40-7.
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Xie J, Hao X, Azeloglu EU, Ren H, Wang Z, Ma J, Liu J, Ma X, Wang W, Pan X, Zhang W, Zhong F, Li Y, Meng G, Kiryluk K, He JC, Gharavi AG,
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Novel mutations in the inverted formin 2 gene of Chinese families contribute to focal segmental glomerulosclerosis.
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Kidney Int.
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2015
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88(3):593-604
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Li X, Zhang W, Yu HJ, Pan XX, Shen PY, Ren H, Wang WM,
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Clinical and pathological study on patients with primary antineutrophil cytoplasmic autoantibody-associated vasculitis with renal immune complex deposition.
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J Clin Rheumatol.
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2015
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21(1):3-9
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Xie J, Wu X, Ren H, Wang W, Wang Z, Pan X, Hao X, Tong J, Ma J, Ye Z, Meng G, Zhu Y, Kiryluk K, Kong X, Hu L,
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COL4A3 mutations cause focal segmental glomerulosclerosis.
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J Mol Cell Biol
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2014
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6(6):498-505
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Wu X, Zhang W, Ren H, Chen X, Xie J,
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Diuretics associated acute kidney injury: clinical and pathological analysis.
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Ren Fail.
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2014
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36(7):1051-5.
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Zhang Q, Ren H, Xie J, Li X, Huang X,
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Causes of death in peritoneal dialysis patients with different kidney diseases and comorbidities: a retrospective clinical analysis in a Chinese center.
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Int Urol Nephrol.
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2014
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46(6):1201-7.
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Zhang Q, Ren H, Xie J, Li X, Huang X,
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Causes of death in peritoneal dialysis patients with different kidney diseases and comorbidities: a retrospective clinical analysis in a Chinese center.
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Int Urol Nephrol.
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2014
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46(6):1201-7.
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Shi H, Zhang W, Li X, Ren H, Pan X,
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Application of RIFLE criteria in patients with multiple myeloma with acute kidney injury: a 15-year retrospective, single center, cohort study.
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Leuk Lymphoma.
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2014
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55(5):1076-82
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, Wu X, Ding X, Mei C, Fu P, Jiang G, Li X, Chen J, Liu B, La Y, Hou F, Ni Z, Fu J, Xing C, Yu X, Huang C, Zuo L, Wang L, Hunter J, Dillon M, Plone M, Neylan J.
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Sevelamer carbonate lowers serum phosphorus effectively in haemodialysis patients: a randomized, double-blind, placebo-controlled, dose-titration study.
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Nephrol Dial Transplant.
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2014
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29(1):152-60.
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Zhang W, Zhang L, Chen YX, Xie YY, Zou YF, Zhang MJ, Gao YH, Liu Y, Zhao Q,, Chen N.
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Identification of nestin as a urinary biomarker for acute kidney injury.
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Am J Nephrol.
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2014
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2014;39(2):110-21.
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Chen YX, Zhang W, Wang WM, Yu XL, Wang YM, Zhang MJ,
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Role of moesin in renal fibrosis.
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PLoS One.
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2014
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18;9(11):e112936.
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Chen YX, Zhang W, Chen XN, Ni LY, Shen PY, Wang WM,
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Clinical analysis of ANCA-associated renal vasculitis patients with chronic dialysis.
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Clin Exp Rheumatol.
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2014
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32(2):S5-10
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Kiryluk K, Li Y, Scolari F, Sanna-Cherchi S, Choi M, Verbitsky M, Fasel D, Lata S, Prakash S, Shapiro S, Fischman C, Snyder HJ, Appel G, Izzi C, Viola BF, Dallera N, Del Vecchio L, Barlassina C, Salvi E, Bertinetto FE, Amoroso A, Savoldi S, Rocchietti M, Amore A, Peruzzi L, Coppo R, Salvadori M, Ravani P, Magistroni R, Ghiggeri GM, Caridi G, Bodria M, Lugani F, Allegri L, Delsante M, Maiorana M, Magnano A, Frasca G, Boer E, Boscutti G, Ponticelli C, Mignani R, Marcantoni C, Di Landro D, Santoro D, Pani A, Polci R, Feriozzi S, Chicca S, Galliani M, Gigante M, Gesualdo L, Zamboli P, Battaglia GG, Garozzo M, Maixnerová D, Tesar V, Eitner F, Rauen T, Floege J, Kovacs T, Nagy J, Mucha K, P?czek L, Zaniew M, Mizerska-Wasiak M, Roszkowska-Blaim M, Pawlaczyk K, Gale D, Barratt J, Thibaudin L, Berthoux F, Canaud G, Boland A, Metzger M, Panzer U, Suzuki H, Goto S, Narita I, Caliskan Y, Xie J, Hou P,, Zhang H, Wyatt RJ, Novak J, Julian BA, Feehally J, Stengel B, Cusi D, Lifton RP, Gharavi AG.
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Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.
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Nat Genet.
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2014
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46(11):1187-96.
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Qian Y, Ren H, Wang ZH, Li X, Chen XN,
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Staging and risk factors of chronic kidney disease of outpatients in Shanghai.
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Ren Fail.
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2014
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36(7):1018-22.
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Pan X, Xu J, Ren H, Zhang W, Xu Y, Shen P, Li X, Wang W, Chen X, Wu P, Feng X, Hao C,
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Changing spectrum of biopsy-proven primary glomerular diseases over the past 15 years: a single-center study in China.
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Contrib Nephrol.
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2013
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181:22-30.
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Hao X, Liu X, Wang W, Ren H, Xie J, Shen P, Lin D,
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Distinct metabolic profile of primary focal segmental glomerulosclerosis revealed by NMR-based metabolomics.
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PLoS One.
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2013
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8(11):e78531.
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Xie J,
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Primary glomerulonephritis in mainland China: an overview.
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Contrib Nephrol.
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2013
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181:1-11.
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Chen X,
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Plasma exchange in the treatment of rapidly progressive glomerulonephritis.
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Contrib Nephrol.
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2013
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181:240-7.
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Ren H, Shen P, Li X, Pan X, Zhang W,
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Tacrolimus versus cyclophosphamide in steroid-dependent or steroid-resistant focal segmental glomerulosclerosis: a randomized controlled trial.
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Am J Nephrol.
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2013
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37(1):84-90
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Jin Y, Liu R, Xie J, Xiong H, He JC,
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Interleukin-10 deficiency aggravates kidney inflammation and fibrosis in the unilateral ureteral obstruction mouse model.
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Lab Invest.
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2013
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93(7):801-11.
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Hao X, Xie J, Ma J, Wang Z, Zhou Q, Yang L, Pan X, Ren H,
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Increased risk of treatment failure and end-stage renal disease in familial focal segmental glomerular sclerosis.
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Contrib Nephrol.
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2013
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181:101-8.
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Wang W,
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Treatment of progressive IgA nephropathy: an update.
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Contrib Nephrol.
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2013
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181:75-83.
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Ren H, Qin L, Wang W, Ma J, Zhang W, Shen PY, Shi H, Li X,
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Abnormal glucose metabolism and insulin sensitivity in Chinese patients with Gitelman syndrome.
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Am J Nephrol.
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2013
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37(2):152-7.
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Lu Y, Shen P, Li X, Xu Y, Pan X, Wang W, Chen X, Zhang W, Ren H,
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Re-evaluation of the classification system for membranoproliferative glomerulonephritis.
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Contrib Nephrol.
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2013
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181:175-84.
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Chen Z, Chen X, Xie J, Ma X, Zhong F, Hou L, Ling H, Li X, Ren H,
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Fibroblast growth factor 23 is a predictor of aortic artery calcification in maintenance hemodialysis patients.
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Ren Fail.
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2013
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35(5):660-6.
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Li Y, Zhang W, Ren H, Wang W, Shi H, Li X, Chen X, Shen P, Wu X, Xie J,
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Evaluation of anemia and serum iPTH, calcium, and phosphorus in patients with primary glomerulonephritis.
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Contrib Nephrol.
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2013
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181:31-40.
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Xu J, Zhang W, Xu Y, Shen P, Ren H, Wang W, Li X, Pan X,
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Tacrolimus combined with corticosteroids in idiopathic membranous nephropathy: a randomized, prospective, controlled trial.
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Contrib Nephrol.
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2013
|
181:152-62.
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Zhang Q, Ma J, Xie J, Wang Z, Zhu B, Hao X, Yang L, Ren H,
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Screening of ACTN4 and TRPC6 mutations in a Chinese cohort of patients with adult-onset familial focal segmental glomerulosclerosis.
|
Contrib Nephrol.
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2013
|
181:91-100.
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Ren H, Shen P, Li X, Pan X, Zhang Q, Feng X, Zhang W,
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Treatment and prognosis of primary focal segmental glomerulosclerosis.
|
Contrib Nephrol.
|
2013
|
181:109-18.
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Li X,
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Management of crescentic glomerulonephritis: what are the recent advances?
|
Management of crescentic glomerulonephritis: what are the recent advances?Li X, Chen N. Contrib Nephrol. 2013;181:229-39. doi: 10.1159/000348479.Epub 2013 May 8.Review.PMID: 23689584 Similar articles. [PMID:23689584]
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2013
|
181:229-39.
|
Chen YX,
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Pathogenesis of rapidly progressive glomerulonephritis: what do we learn?
|
Contrib Nephrol.
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2013
|
181:207-15.
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, Pan XX, Gu Y, Mao PJ, Ni ZH, Ding XQ, Zhang JH, Wang NS, Yuan WJ, Zhang JY
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Analysis of early kidney damage in hospitalized patients with chronic kidney disease: a multicenter study
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Ren Fail
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2012
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34(3):329-33
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Jin Y, Ratnam K, Chuang PY, Fan Y, Zhong Y, Dai Y, Mazloom AR, Chen EY, D'Agati V, Xiong H, Ross MJ,, Ma'ayan A, He JC
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A systems approach identifies HIPK2 as a key regulator of kidney fibrosis
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Nat Med
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2012
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18(4):580-8
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Shao L, Lang Y, Wang Y, Gao Y, Zhang W, Niu H, Liu S,
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High-frequency variant p.T60M in NaCl cotransporter and blood pressure variability in Han Chinese
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Am J Nephrol
|
2012
|
35(6):515-9.
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Zhang L, Wang F, Wang L, Wang W, Liu B, Liu J, Chen M, He Q, Liao Y, Yu X,, Zhang JE, Hu Z, Liu F, Hong D, Ma L, Liu H, Zhou X, Chen J, Pan L, Chen W, Wang W, Li X, Wang H
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Prevalence of chronic kidney disease in China: a cross-sectional survey
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Lancet
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2012
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379(9818):815-22
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Li X, Ren H, Zhang Q, Zhang W, Wu X, Xu Y, Shen P,
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Mycophenolate mofetil or tacrolimus compared with intravenous cyclophosphamide in the induction treatment for active lupus nephritis
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Nephrol Dial Transplant
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2012
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27(4):1467-72
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Chen YX, Zhang W, Chen XN, Yu HJ, Ni LY, Xu J, Pan XX, Ren H,
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Propylthiouracil-induced antineutrophil cytoplasmic antibody (ANCA)-associated renal vasculitis versus primary ANCA-associated renal vasculitis: a comparative study
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J Rheumatol
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2012
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39(3):558-63
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Shao L, Lang Y, Wang Y, Gao Y, Zhang W, Niu H, Liu S,
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High-frequency variant p.T60M in NaCl cotransporter and blood pressure variability in Han Chinese
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Am J Nephrol
|
2012
|
35(6):515-9
|
Zhong F, Liu X, Zhou Q, Hao X, Lu Y, Guo S, Wang W, Lin D,
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1H NMR spectroscopy analysis of metabolites in the kidneys provides new insight into pathophysiological mechanisms: applications for treatment with Cordyceps sinensis
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Nephrol Dial Transplant
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2012
|
27(2):556-65
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Kong X, Zhang L, Zhang L,, Gu Y, Yu X, Liu W, Chen J, Peng L, Yuan W, Wu H, Chen W, Fan M, He L, Ding F, Chen X, Xiong Z, Zhang J, Jia Q, Shi W, Xing C, Tang X, Hou F, Shu G, Mei C, Wang L, Xu D, Ni Z, Zuo L, Wang M, Wang H
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High-frequency variant p.T60M in NaCl Mineral and bone disorder in Chinese dialysis patients: a multicenter study
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BMC Nephrol
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2012
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13:116-122
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Wang J, Long Q, Zhang W,
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Protective effects of exogenous interleukin 18-binding protein in a rat model of acute renal ischemia-reperfusion injury
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Shock
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2012
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37(3):333-40
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Xie J, Kiryluk K, Wang W, Wang Z, Guo S, Shen P, Ren H, Pan X, Chen X, Zhang W, Li X, Shi H, Li Y, Gharavi AG,
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Predicting progression of IgA nephropathy: new clinical progression risk score
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PLoS One
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2012
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7(6):1-8
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Zeng CH, Le W, Ni Z, Zhang M, Miao L, Luo P, Wang R, Lv Z, Chen J, Tian J,, Pan X, Fu P, Hu Z, Wang L, Fan Q, Zheng H, Zhang D, Wang Y, Huo Y, Lin H, Chen S, Sun S, Wang Y, Liu Z, Liu D, Ma L, Pan T, Zhang A, Jiang X, Xing C, Sun B, Zhou Q, Tang W,
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A multicenter application and evaluation of the oxford classification of IgA nephropathy in adult chinese patients
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Am J Kidney Dis
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2012
|
60(5):812-20.
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Zhang W, Shen PY, Chen YX, Zhu P, Shi H, Li X, Xu YW, Ren H,
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Analyzing Chinese patients with post-operative acute kidney injury
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Ren Fail
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2011
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33(8):795-800
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Xie J, Kiryluk K, Ren H, Zhu P, Huang X, Shen P, Xu T, Chen X,
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Coiled versus straight peritoneal dialysis catheters: a randomized controlled trial and meta-analysis
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Am J Kidney Dis
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2011
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58(6):946-55
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Xu J, Wang W, Shi H, Chen S, Liu Z, Li W, Zhang J, Li Y,
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Chronic kidney disease is prevalent in Chinese patients admitted with verified cerebrovascular lesions and predicts short-term prognosis
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Nephrol Dial Transplant
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2011
|
26(8):2590-4
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Ma J, Pan X, Wang Z, Wang Y, Feng X, Ren H, Zhang W, Chen X, Wang W,
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Twenty-one novel mutations identified in the COL4A5 gene in Chinese patients with X-linked Alport's syndrome confirmed by skin biopsy
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Nephrol Dial Transplant
|
2011
|
26(12):4003-10.
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Chen XN, Pan XX, Yu HJ, Shen PY, Zhang QY, Zhang W, Ren H, Qian Y, Zhu P,
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Analysis of cardiovascular disease in Chinese inpatients with chronic kidney disease
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Intern Med
|
2011
|
50(17):1797-801
|
Ratnam KK, Feng X, Chuang PY, Verma V, Lu TC, Wang J, Jin Y, Farias EF, Napoli JL,, Kaufman L, Takano T, D'Agati VD, Klotman PE, He JC
|
Role of the retinoic acid receptor-α in HIV-associated nephropathy
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Kidney Int
|
2011
|
79(6):624-34
|
Wang J, Du Z, Zhang W, Han B, Peng C,
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Post liver transplantation acute kidney injury in a rat model of syngeneic orthotopic liver transplantation
|
Lab Invest
|
2011
|
91(8):1158-69
|
Chen YX, Zhang W, Chen XN, Shen PY, Shi H, Xu YW, Ren H,
|
Application of RIFLE criteria in Chinese patients with ANCA-associated renal vasculitis
|
Clin Exp Rheumatol
|
2011
|
29(6):951-7
|
Zhang W, Chen X, Chen Y,
|
Clinical experience with nadroparin in patients undergoing dialysis for renal impairment
|
Hemodial Int
|
2011
|
27(2):556-65
|
Zhang C, Wang Z, Xie J, Yan F, Wang W, Feng X, Zhang W,
|
Identification of a novel WNK4 mutation in Chinese patients with pseudohypoaldosteronism type II
|
Nephron Physiol
|
2011
|
118(3):p53-61
|
Chen YX, Li Y, Wang WM, Zhang W, Chen XN, Xie YY, Lu J, Huang QH,
|
Phosphoproteomic study of human tubular epithelial cell in response to transforming growth factor-beta-1-induced epithelial-to-mesenchymal transition
|
Am J Nephrol
|
2010
|
31(1):24-35
|
, Hsu CC, Yamagata K, Langham R
|
Challenging chronic kidney disease: experience from chronic kidney disease prevention programs in Shanghai, Japan, Taiwan and Australia
|
Nephrology (Carlton)
|
2010
|
15 Suppl 2:31-6
|
Wang Y, Wang Z, Wang W, Ren H, Zhang W,
|
Analysis of factors associated with renal function in Chinese adults with congenital solitary kidney
|
Intern Med
|
2010
|
49(20):2203-9
|
Xie JY, Ren H, Kiryluk K,
|
Peritoneal dialysis outflow failure from omental wrapping diagnosed by catheterography
|
Am J Kidney Dis
|
2010
|
56(5):1006-11
|
Dai S, Wang Z, Pan X, Wang W, Chen X, Ren H, Hao C, Han B,
|
Functional analysis of promoter mutations in the ACTN4 and SYNPO genes in focal segmental glomerulosclerosis
|
Nephrol Dial Transplant
|
2010
|
25(3):824-35
|
Xie JY,, Ren H, Wang WM
|
Angiotensin II-mediated activation of fibrotic pathways through ERK1/2 in rat peritoneal mesothelial cells
|
Ren Fail
|
2010
|
32(7):871-9
|
Xie JY,, Ren H, Wang WM
|
Angiotensin II-mediated activation of fibrotic pathways through ERK1/2 in rat peritoneal mesothelial cells
|
Ren Fail
|
2010
|
32(7):871-9
|
Ling Qin, Leping Shao, Hong Ren, Weiming Wang, Xiaoxia Pan, Wen Zhang, Zhaohui Wang, Pingyan Shen,
|
Identification of five novel variants in the thiazide-sensitive NaCl co-transporter gene in Chinese patients with Gitelman syndrome
|
Nephrology
|
2009
|
14(1):52-58
|
Dai S, Wang Z, Pan X, Wang W, Chen X, Ren H, Hao C, Han B, Chen N.
|
Functional analysis of promoter mutations in the ACTN4 and SYNPO genes in focal segmental glomerulosclerosis
|
Nephrol Dial Transplant
|
2009
|
112(3):177-83
|
Zhu B,, Wang ZH, Pan XX, Ren H, Zhang W, Wang WM.
|
Identification and functional analysis of a novel TRPC6 mutation associated with late onset familial focal segmental glomerulosclerosis in Chinese patients
|
Mutat Res
|
2009
|
664(1-2):84-90
|
Dai S, Wang Z, Pan X, Chen X, Wang W, Ren H, Feng Q, He JC, Han B,
|
ACTN4 Gene Mutations and Single Nucleotide Polymorphisms in Idiopathic Focal Segmental Glomerulosclerosis
|
Nephron Clin Pract
|
2009
|
111(2):c87-c94
|
Wang WM, Zhang HD, Jin YM, Zhu BB,
|
PPAR-gamma agonists inhibit TGF-beta1-induced chemokine expression in human tubular epithelial cells
|
Acta Pharmacol Sin
|
2009
|
30(1):107-112
|
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