- 基本信息
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导师姓名：
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曹禹
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学科代码：
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100100
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性别：
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男
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学科名称：
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基础医学
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培养单位：
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附属第九人民医院
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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联系方式：
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专业领域代码：
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邮编：
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邮箱地址：
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yu.cao@shsmu.edu.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
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Science Bulletin, Associate Editor
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中国生物物理学会纳米生物学分会，理事
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- 科研项目
| 82072468 | 骨骼天然免疫信号通路与成骨作用关键分子过程的互联机制研究 | 国家自然科学基金 |
2021-01~2024-12
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55万元
| 课题负责人 |
| 2018YFC1004700 | 基于代谢偶联的生殖细胞发生障碍研究与生育力重塑 | 科技部国家重点研发计划 |
2018-12~2021-12
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438万元
| 子课题负责人 |
| 2017YFC1001301 | 人类早期胚胎发育中细胞编程与重编程的过程及机制 | 科技部国家重点研发计划 |
2017-07~2020-12
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539万元
| 课题参与人 |
| U1632132 | 甾类激素合成途径中生物大分子功能簇的结构与功能研究 | 国家自然科学基金委员会 联合基金项目 |
2017-01~2019-12
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70万元
| 课题负责人 |
| 31670849 | 胰高血糖素样肽受体的结构与功能研究 | 国家自然科学基金委员会 面上项目 |
2017-01~2020-12
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60万元
| 课题负责人 |
| 无 | 千人计划（青年项目） | 中组部 |
2015-07~2017-12
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300万元
| 课题负责人 |
| 15PJ1409100 | II型糖尿病治疗靶点的结构研究与药物开发 | 上海市科学技术委员会 浦江人才计划 |
2015-07~2017-06
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20万元
| 课题负责人 |
- 学术论文
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Li Zhang,Deqiang Yao,Ying Xia,Fu Zhou,Qing Zhang,Qian Wang,An Qin,Jie Zhao,Dianfan Li,Yan Li,Lu Zhou,
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The structural basis for glycerol permeation by human AQP7
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Science Bulletin
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2021
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66(15): 1550-1558
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Qing Zhang,Deqiang Yao,Bing Rao,Liyan Jian,Yang Chen,Kexin Hu,Ying Xia,Shaobai Li,Yafeng Shen,An Qin,Jie Zhao,Lu Zhou,Ming Lei,Xian-Cheng Jiang,
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The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3
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NATURE COMMUNICATIONS
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2021
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12: 6869
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Bing Rao,Shaobai Li,Deqiang Yao,Qian Wang,Ying Xia,Yi Jia,Yafeng Shen,
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The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1
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Science Advances
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2021
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7: eabe8591
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F. Zhou, D. Yao, B. Rao, L. Zhang, W., Nie, Y.,, J, Zhao, Y. Cao
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Crystal structure of a bacterial homolog to human lysosomal transporter, spinster
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Science Bulletin
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2019
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64(18): 1310-1317
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Lou B, Liu Q, Hou J, Kabir I, Liu P, Ding T, Dong J, Mo M, Ye D, Chen Y, Bui HH, Roth K,, Jiang XC
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2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity.
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J Biol Chem
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2019
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293(47):18328-18336
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Yang Chen, Ying Xia,
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A Historical Perspective of G Protein-Coupled Receptor Structural Biology
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Advances in Membrane Proteins
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2019
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Vol 2: 31-47
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Ying Xia,
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Membrane As the Barrier of Life
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Advances in Membrane Proteins
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2018
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Vol 1: 1-16
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Yang Chen and Yu Cao
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The sphingomyelin synthase family: proteins, diseases and inhibitors.
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Biological Chemistry
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2017
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Epub
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, Yaping Pan, Hua Huang, Xiangshu Jin, Elena Levin, Ming Zhou
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Gating of the TrkH ion channel by its associated RCK protein, TrkA
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Nature
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2013
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496:317–322
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Elena Levin,, Giray Enkavi, Matthias Quick, Yaping Pan, Emad Tajkhorshid, Ming Zhou
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Structure and permeation mechanism of a mammalian urea transporter
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Proc Natl Acad Sci U S A
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2012
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109(28):11194-9
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, Xiangshu Jin, Elena Levin, Hua Huang, Yinong Zong, Matthias Quick, Jun Weng, Yaping Pan, James Love, Marco Punta, Burkhard Rost, Wayne Hendrickson, Jonathan Javitch, Ming Zhou
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Crystal structure of a phosphorylation-coupled saccharide transporter
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Nature
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2011
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473:50-54
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, Xiangshu Jin, Hua Huang, Mehabaw Derebe, Elena Levin, Venkataraman Kabaleeswaran, Yaping Pan, Marco Punta, James Love, Jun Weng, Matthias Quick, Sheng Ye, Brian Kloss, Renato Bruni, Erik Martinez-Hackert, Wayne Hendrickson, Burkhard Rost, Jonathan Javitch, Kanagalaghatta Rajashankar, Youxing Jiang, Ming Zhou
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Crystal structure of a potassium ion transporter TrkH
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Nature
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2011
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471:336-340
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