- 基本信息
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导师姓名：
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陈磊
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学科代码：
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100100
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性别：
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男
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学科名称：
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基础医学
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培养单位：
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附属仁济医院
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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联系方式：
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专业领域代码：
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邮编：
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邮箱地址：
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lei.chen@sjtu.edu.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
- 科研项目
| 2017年9月第十三批生命科学组 | 肠道微生物对人类慢性疾病的影响 | 海外高层次人才 |
2017-05~2020-12
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200万元
| 课题负责人 |
- 学术论文
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Wenyu Zhou, M. Reza Sailani, Kévin Contrepois, Yanjiao Zhou, Sara Ahadi, Shana R. Leopold, Martin J. Zhang, Varsha Rao, Monika Avina, Tejaswini Mishra, Jethro Johnson, Brittany Lee-McMullen, Songjie Chen, Ahmed A. Metwally, Thi Dong Binh Tran, Hoan Nguyen, Xin Zhou, Brandon Albright, Bo-Young Hong, Lauren Petersen, Eddy Bautista, Blake Hanson,, Daniel Spakowicz, Amir Bahmani, Denis Salins, Benjamin Leopold, Melanie Ashland, Orit Dagan-Rosenfeld, Shannon Rego, Patricia Limcaoco, Elizabeth Colbert, Candice Allister, Dalia Perelman, Colleen Craig, Eric Wei, Hassan Chaib, Daniel Hornburg, Jessilyn Dunn, Liang Liang, Sophia Miryam Schüssler-Fiorenza Rose, Kim Kukurba, Brian Piening, Hannes Rost, David Tse, Tracey McLaughlin, Erica Sodergren, George M. Weinstock & Michael Snyder
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Longitudinal multi-omics of host–microbe dynamics in prediabetes
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Nature
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2019
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2019, 569: 663-671.
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Li QZ1, Chang YZ, He ZM,, Zhou XW.
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Immunomodulatory activity of Ganoderma lucidum immunomodulatory protein via PI3K/Akt and MAPK signaling pathways in RAW264.7 cells.
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Journal of Cellular Physiology
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2019
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(2019)
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Jiyu Tong, Guangchao Cao, Ting Zhang, Esen Sefik, Maria Carolina Amezcua Vesely, James P Broughton, Shu Zhu, Huabin Li, Bin Li,, Howard Y Chang, Bing Su, Richard A Flavell, Hua-Bing Li1
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m6A mRNA methylation sustains Treg suppressive functions
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Cell Research
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2018
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(2018)
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Xiaoyan Yu, Yimin Lao, Xiao-Lu Teng, Song Li, Yan Zhou, Feixiang Wang, Xinwei Guo, Siyu Deng, Yuzhou Chang, Xuefeng Wu, Zhiduo Liu,, Li-Ming Lu, Jinke Cheng, Bin Li, Bing Su, Jin Jiang, Hua-Bing Li, Chuanxin Huang, Jing Yi,Qiang
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SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
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Nature Communications
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2018
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2018, 9(1)
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Qian Chen, Yiping Ren, Jihong Lu, Mark Bartlett,, Yan Zhang, Xiaokui Guo, Chang Liu
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A Novel Prebiotic Blend Product Prevents Irritable Bowel Syndrome in Mice by Improving Gut Microbiota and Modulating Immune Response
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Nutrients
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2017
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2017, 9(12).
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Staudová B, Strouhal M, Zobaníková M, Cejková D, Fulton LL,, Giacani L, Centurion-Lara A, Bruisten SM, Sodergren E, Weinstock GM, Smajs D
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Whole genome sequence of the Treponema pallidum subsp. endemicum strain Bosnia A: the genome is related to yaws treponemes but contains few loci similar to syphilis treponemes.
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PLoS Negl Trop Dis
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2014
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Nov 6,8(11):e3261
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Zhou Y, Burnham CA, Hink T,, Shaikh N, Wollam A, Sodergren E, Weinstock GM, Tarr PI, Dubberke ER
Devin P; Martin, John C; Chen, Lei; Mitreva, Makedonka; Miller, Jason R; Haub,
Kevin V; Dooling, David J; Mardis, Elaine R; Wilson, Richard K; Weinstock,
George M; Warren, Wesley C ,
(*)
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Phenotypic and genotypic analysis of Clostridium difficile isolates: a single-center study.
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Clin Microbiol
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2014
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Dec,52(12):4260-6
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Chen K,, Fan X, Wallis J, Ding L, Weinstock G.
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TIGRA: a targeted iterative graph routing assembler for breakpoint assembly. Genome Res
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Genome Res
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2014
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Feb,24(2):310-7
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Zhou, Yanjiao ; Burnham, Carey-Ann D; Hink,, Lei; Shaikh, Nurmohammad; Wollam, Aye; Sodergren, Erica; Weinstock, George M; Tarr,Phillip I; Dubberke, Erik R
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Phenotypic and genotypic analysis of Clostridium difficile isolates: a single-center study.
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J Clin Microbiol
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2014
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52(12): 4260~4266
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Cejková D, Zobaníková M,, Pospí?ilová P, Strouhal M, Qin X, Mikalová L, Norris SJ, Muzny DM, Gibbs RA, Fulton LL, Sodergren E, Weinstock GM, Smajs D.
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Whole genome sequences of three Treponema pallidum ssp. pertenue strains: yaws and syphilis treponemes differ in less than 0.2% of the genome sequence.
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PLoS Negl Trop Dis
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2012
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Jan,6(1):e1471
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e L, Hillier LW, Minx P, Thane N, Locke DP, Martin JC,, Mitreva M, Miller JR, Haub KV, Dooling DJ, Mardis ER, Wilson RK, Weinstock GM, Warren WC.
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A vertebrate case study of the quality of assemblies derived from next-generation sequences
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Genome Biol
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2011
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12(3):R31
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Nelson, Karen E ; Weinstock, George M; Highlander, Sarah K; Worley,Kim C; Creasy, Heather Huot; Wortman, Jennifer Russo; Rusch, Douglas B;Mitreva, Makedonka; Sodergren, Erica; Chinwalla, Asif T; Feldgarden, Michael;Gevers, Dirk; Haas, Brian J; Madupu, Ramana; Ward, Doyle V; Birren, Bruce W;Gibbs, Richard A; Methe, Barbara; Petrosino, Joseph F; Strausberg, Robert L;Sutton, Granger G; White, Owen R; Wilson, Richard K; Durkin, Scott; Giglio,Michelle Gwinn; Gujja, Sharvari; Howarth, Clint; Kodira, Chinnappa D; Kyrpides,Nikos; Mehta, Teena; Muzny, Donna M; Pearson, Matthew; Pepin, Kymberlie; Pati,Amrita; Qin, Xiang; Yandava, Chandri; Zeng, Qiandong; Zhang, Lan; Berlin,,Lei; Hepburn, Theresa A; Johnson, Justin; McCorrison, Jamison;Miller, Jason; Minx, Pat; Nusbaum, Chad; Russ, Carsten; Sykes, Sean M;Tomlinson, Chad M; Young, Sarah; Warren, Wesley C; Badger, Jonathan; Crabtree,Jonathan; Markowitz, Victor M; Orvis, Joshua; Cree, Andrew; Ferriera, Steve;Fulton, Lucinda L; Fulton, Robert S; Gillis, Marcus; Hemphill, Lisa D; Joshi,Vandita; Kovar, Christie; Torralba, Manolito; Wetterstrand, Kris A;Abouellleil, Amr; Wollam, Aye M; Buhay, Christian J; Ding, Yan; Dugan, Shannon;FitzGerald, Michael G; Holder, Mike; Hostetler, Jessica; Clifton, Sandra W;Allen-Vercoe, Emma; Earl, Ashlee M; Farmer, Candace N; Liolios, Konstantinos;Surette, Michael G; Xu, Qiang; Pohl, Craig; Wilczek-Boney, Katarzyna; Zhu,Dianhui
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A catalog of reference genomes from the human microbiome.
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Scienc
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2010
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328(5981): 994~999
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Ding L, Ellis MJ, Li S, Larson DE, Chen K, Wallis JW, Harris CC, McLellan MD, Fulton RS, Fulton LL, Abbott RM, Hoog J, Dooling DJ, Koboldt DC, Schmidt H, Kalicki J, Zhang Q,, Lin L, Wendl MC, McMichael JF, Magrini VJ, Cook L, McGrath SD, Vickery TL, Appelbaum E, Deschryver K, Davies S, Guli T, Lin L, Crowder R, Tao Y, Snider JE, Smith SM, Dukes AF, Sanderson GE, Pohl CS, Delehaunty KD, Fronick CC, Pape KA, Reed JS, Robinson JS, Hodges JS, Schierding W, Dees ND, Shen D, Locke DP, Wiechert ME, Eldred JM, Peck JB, Oberkfell BJ, Lolofie JT, Du F, Hawkins AE, OLaughlin MD, Bernard KE, Cunningham M, Elliott G, Mason MD, Thompson DM Jr, Ivanovich JL, Goodfellow PJ, Perou CM, Weinstock GM, Aft R, Watson M, Ley TJ, Wilson RK, Mardis ER.
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Genome remodelling in a basal-like breast cancer metastasis and xenograft
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Nature
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2010
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Apr 15,464(7291):999-1005.
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