• 基本信息
    导师姓名： 代杰文 学科代码： 100302
    性别： 男 学科名称： 口腔临床医学
    培养单位： 口腔医学院 三级学科
    导师类型： 博士生导师 专业领域名称： 口腔医学 专业学位
    联系方式： 专业领域代码： 105200
    邮编： 邮箱地址： daijiewen@163.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    中华口腔医学会口腔遗传病与罕见病专委会常委
    中华口腔医学会口腔生物医学专委会青年委员
    上海市口腔医学会口腔遗传病与罕见病专委会 常委，学术秘书
    上海市口腔医学会口腔颌面外科专委会委员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    8237090622q11.2染色体微重复影响TOP3B表达并导致腭裂发生的机制研究国家自然科学基金面上项目 2024-01~2027-12 48万元  课题负责人
    20234Z0006评价Zingg A型颧骨上颌骨骨折患者眶下神经受压损伤早期手术与保守治疗有效性及安全性的随机、平行对照、开放性研究上海市卫健委卓越项目（含上海市杰出青年医师项目） 2023-01~2025-12 50万元  课题负责人
    82071097组织特异性增强子调控Sox9在下颌骨精确性时空表达及参与Pierre-Robin综合征发生的机制研究国家自然科学基金面上项目 2021-01~2024-12 58万元  课题负责人
    81741028胎儿第一、二鳃弓局部出血、血肿在半侧颜面发育不全发生中的致畸作用及分子机制研究国家自然科学基金应急管理项目 2018-01~2018-12 20万元  课题负责人
    YG2016MS08三维虚拟正颌手术中下颌骨运动的精确模拟与应用研究上海交通大学医工交叉面上项目 2017-01~2019-12 21万元  课题负责人
    /上海市青年拔尖人才上海市委组织部 2016-12~2019-12 15万元  课题负责人
    /Fibulin-7在腭裂和心血管畸形发生中的作用及机制研究上海交通大学晨星学者奖励计划（C类） 2016-07~2017-06 2万元  课题负责人
    /上海市青年医师培养资助计划上海市卫生与计划生育委员会 2016-01~2018-12 6万元  课题负责人
    YB150619“5+3”模式下口腔医学本科生外科临床能力培养的教学探索:以颌面部创伤与畸形整复病房实习为例上海交通大学医学院 2015-07~2016-12 0.8万元  课题负责人
    /Fibulin-7基因敲除小鼠的初步分析上海交通大学医学院附属第九人民医院-第七届院优青 2015-01~2017-12 6万元  课题负责人
    81300842Dlx2/Fgf9/p53信号通路在颅神经嵴细胞发育中的作用研究国家自然科学基金青年项目 2014-01~2016-12 23万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Liu H, Tsai H, Yang M, Li G, Bian Q, Ding G, Wu D,  Three-dimensional genome structure and function  MedComm  2023  4(4):e326 
    Hanjiang Zhao, Xiangyu Wang, Anting Jin, Minjiao Wang, Zeying Wang, Xingtai Huang,, Xudong Wang, Dan Lin, Steve GF. Shen  Reducing relapse and accelerating osteogenesis in rapid maxillary expansion using an injectable mesoporous bioactive glass/fibrin glue composite hydrogel   Bioact Mater  2022  18:507-525 
    Huang X, Wang Q, Mao R, Wang Z, Shen SGF, Mou J,  Two-dimensional nanovermiculite and polycaprolactone electrospun fibers composite scaffolds promoting diabetic wound healing  J Nanobiotechnology  2022  26;20(1):343 
    Qiming Chen,, Qian Bian  Integration of 3D genome topology and local chromatin features uncovers enhancers underlying craniofacial-specific cartilage defects  SCIENCE ADVANCES  2022  8(47): eabo3648 
    Ouyang N, Zhao Y, Chen Q, Chen L, Fang B,, Shen G.  The Effect of Celecoxib in Traumatic Heterotopic Ossification around Temporomandibular Joint in Mice.  Osteoarthritis and Cartilage  2020  DOI: https://doi.org/10.1016/j.joca.2020.01.014 
    Zhao Y, Chen Q, Chen L, Shen SGF,  Thalidomide leads to mandible hypoplasia through inhibiting angiogenesis and secondary hemorrhage in the fetal craniofacial region in rabbits  Toxicol Lett  2020  2020;319:250-255. 
    Zhao Y, Liu P, Chen Q, Ouyang N, Lin Y, Zhang W,, Shen G  Development process of traumatic heterotopic ossification of the temporomandibular joint in mice  J Craniomaxillofac Surg  2019  47(7):1155-1161 
    Wu D, Chen Y, Chen Q, Wang G, Xu X, Peng A, Hao J, He J, Huang L,  Clinical presentation and genetic profiles of Chinese patients with velocardiofacial syndrome in a large referral centre  J Genet  2019  98(2). pii: 8. 
    Chen Q, Zhao Y, Qian Y, Lu C, Shen G,  A genetic-phenotypic classification for syndromic micrognathia  J Hum Genet  2019  64(9):875-883 
    Yu J, Yang T,, Wang X.  Histopathological features of condylar hyperplasia and condylar Osteochondroma: a comparison study  Orphanet J Rare Dis  2019  14(1):293 
    Zhang J, Zhang W, Shi J,, Shen SG  Dlx2 overexpression enhanced accumulation of type II collagen and aggrecan by inhibiting MMP13 expression in mice chondrocytes  Biochem Biophys Res Commun  2018  503(2):528-535 
    Ouyang N, Zhu X, Li H, Lin Y, Shi J,, Shen G  Effects of a single condylar neck fracture without condylar cartilage injury on traumatic heterotopic ossification around the temporomandibular joint in mice  Oral Surg Oral Med Oral Pathol Oral Radiol  2018  125(2):120-125 
    Chen Q, Zhao Y, Shen G,  Etiology and Pathogenesis of Hemifacial Microsomia  J Dent Res  2018  97(12):1297-1305 
    , Si J, Ouyang N, Zhang J, Wu D, Wang X, Shen G  Dental and periodontal phenotypes of Dlx2 overexpression in mice  Mol Med Rep   2017  15(5):2443-2450 
    Wu D, Wang G, Ouyang N, Lin Y, Chen Y,  Subcutaneous C Shape Muscular Flap for Correcting the Depression of Alar Base in Affected Side in Patients With Unilateral Complete Cleft Lip/Palate During Primary Surgery  J Craniofac Surg   2017  28(4):1078-1080 
    , Ouyang N, Zhu X, Huang L, Shen G.  Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis  J Craniomaxillofac Surg  2016  44(3):294-300 
    , Wu J, Wang X, Yang X, Wu Y, Xu B, Shi J, Yu H, Cai M, Zhang W, Zhang L, Sun H, Shen G, Zhang S.  An excellent navigation system and experience in craniomaxillofacial navigation surgery: a double-center study  Sci Rep  2016  16;6:28242 
    , Shen G, Yuan H, Zhang W, Shen S, Shi J  Titanium Mesh Shaping and Fixation for the Treatment of Comminuted Mandibular Fractures  J Oral Maxillofac Surg  2016  74(2):337.e1-337.e11 
    , Si J, Wang M, Huang L, Fang B, Shi J, Wang X, Shen G  Tcof1-Related Molecular Networks in Treacher Collins Syndrome  J Craniofac Surg   2016  27(6):1420-6 
    , Si J, Zhu X, Zhang L, Wu D, Lu J, Ouyang N, Wang X, Shen G  Overexpression of Dlx2 leads to postnatal condyle degradation  Mol Med Rep  2016  14(2):1624-30 
    , Yu H, Si J, Fang B, Shen SG.  Irf6-Related Gene Regulatory Network Involved in Palate and Lip Development  J Craniofac Surg  2015  26(5):1600-5 
    , Li H, Yu H, Si J, Fang B, Shen SG  A correlational study of serum alkaline phosphatase level and developmental mandibular laterognathism  J Craniofac Surg   2015  26(2):553-6 
    Si J,, Zhang J, Liu S, Gu J, Shi J, Shen SG, Guo L  Comparative investigation of human amniotic epithelial cells and mesenchymal stem cells for application in bone tissue engineering  Stem Cells Int  2015  2015:565732 
    , Yu H, Wu J, Yu D, Shen SG, Xu B, Zhang S  Le Fort I osteotomy combined with endoscopic assistance for treatment of compound fracture of maxilla, zygoma, and orbital floor  J Craniofac Surg   2014  25(2):495-8 
    , Tang M, Xin P, Hu G, Si J, Dong Y, Xiao C, Shen SG  Accurate movement of jaw segment in virtual 3D orthognathic surgery  J Craniofac Surg   2014  25(2):e140-3 
    , Mou Z, Shen S, Dong Y, Yang T, Shen SG  Bioinformatic analysis of Msx1 and Msx2 involved in craniofacial development  J Craniofac Surg   2014  25(1):129-34 
    , Dong Y, Xin P, Hu G, Xiao C, Shen S, Shen SG  A novel method to determine the potential rotational axis of the mandible during virtual three-dimensional orthognathic surgery  J Craniofac Surg   2013  24(6):2014-7 
    , Shen SG, Zhang S, Wang X, Zhang W, Zhang L  Rapid and accurate identification of cut ends of facial nerves using a nerve monitoring system during surgical exploration and anastomosis  J Oral Maxillofac Surg  2013  71(10):1809.e1-5 
    , Kuang Y, Fang B, Gong H, Lu S, Mou Z, Sun H, Dong Y, Lu J, Zhang W, Zhang J, Wang Z, Wang X, Shen G.  The effect of overexpression of Dlx2 on the migration, proliferation and osteogenic differentiation of cranial neural crest stem cells  Biomaterials  2013  34(8):1898-910 
    , Wang X, Hu G, Shen SG  A new method to move mandible to intercuspal position in virtual three-dimensional orthognathic surgery by integrating primary occlusion model  J Oral Maxillofac Surg   2012  70(9):e484-9