• 基本信息
    导师姓名: 杨泽勇 学科代码: 100217
    性别: 学科名称: 麻醉学
    培养单位: 附属国际和平妇幼保健院 三级学科
    导师类型: 硕士生导师 专业领域名称: 麻醉学 专业学位
    联系方式: 上海交通大学医学院附属国际和平妇幼保健院 麻醉科 地址:上海市衡山路910号 / 华山路1961号 200030 专业领域代码: 105118
    邮编: 200030 邮箱地址: yankylge@aliyun.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    YG2022ZD029 丙泊酚联合东莨菪碱介导PVT-Orexin通路改善失眠小鼠的神经环路机制研究上海交通大学医工交叉重点项目 2022-01~2024-12 100万元  课题负责人
    18ZR1443100YAP/TEAD信号通路反式激活调节氯胺酮所致胚胎神经干细胞毒性的分子机制上海自然基金 2018-01~2020-12 20万元  课题负责人
    TM201729子痫前期及相关神经毒性早期诊断模型构建上海交通大学转化医学项目 2017-11~2020-11 11万元  课题负责人
    81401279自噬对七氟醚致神经细胞损伤的保护作用分子机制 国家自然科学基金青年项目 2015-01~2017-12 23万元  课题负责人
    20140706自噬调节InsIP3R 途径在七氟醚引起胚胎神经干细胞损伤的机制研究上海市麻醉学会培育基金 2015-01~2017-12 3万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Wu Y, Yang M, Xu X, Gao Y, Li X, Li Y, Su S, Xie X,, Ke C.   Thrombospondin 4, a mediator and candidate indicator of pain.  Eur J Cell Biol.  2024  Feb 6;103(2):151395. 
    Yin D, Zhao L, Deng S, Xie Y, Ro KS,, Du L, Xie J, Wei D.   Lactiplantibacillus plantarum X7022 Plays Roles on Aging Mice with Memory Impairment Induced by D-Galactose Through Restoring Neuronal Damage, Relieving Inflammation and Oxidative Stress.  Probiotics Antimicrob Proteins.  2024  Jan 6. 
    Yi Jin,Xiaoxue Hu,Fanhua Meng,Qing Luo,Henry Liu,  Sevoflurane Exposure of Clinical Doses in Pregnant Rats Induces Vcan Changes without Significant Neural Apoptosis in the Offspring  Medicina   2023  2023, 59(2), 190; https://doi.org/10.3390/medicina59020190 
    Wei Y, Wang Y, Zhao Y, Wu C, Liu H,  High Dosage of Patient-Controlled Epidural Analgesia (PCEA) with Low Background Infusion during Labor: A Randomized Controlled Trial  J Pers Med .   2023  2023 Mar 29;13(4):600. 
    Chen L,, Liu H.   Hemoglobin-Based Oxygen Carriers: Where Are We Now in 2023?  Medicina (Kaunas).  2023  Feb 17;59(2):396. 
    Wang Y,  METTL3 relieved the injury of SH-SY5Y cells treated with lipopolysaccharide and exposed to sevoflurane through regulating the m6A levels of Sox2.  Brain Behav.  2023  May;13(5):e2936.  
    Wang Y, Zuo S, Ma Y, Shen J, Chu Q,  Effect of Ultrasound-guided Erector Spinae Plane Block on Recovery After Laparoscopic Sleeve Gastrectomy in Patients With Obesity: A Randomized Controlled Trial  Clin Ther.   2023  Sep;45(9):894-900. 
    , Zhang W, Lu H, Cai S.  Methylglyoxal in the Brain: From Glycolytic Metabolite to Signalling Molecule.  Molecules.   2022  Nov 15;27(22):7905 
    Lv J, Cheng H, Yao W, Liu C, Chen Y, Jin X,, Li Y.   4.8% sevoflurane induces activation of autophagy in human neuroblastoma SH-SY5Y cells by the AMPK/mTOR signaling pathway.  Neurotoxicology  2022  May;90:256-264.  
    Xuan W, Lu X,, Li J, Jin W, Li Y.   Propofol Protects Against Erastin-Induced Ferroptosis in HT-22 Cells.  Journal of Molecular Neuroscience  2022  Sep;72(9):1797-1808. 
    Wu Y,, Su S, Xu X, Li Y, Li X, Gao Y, Sun D, Wan S, Pen M, Jin W, Ke C.   Differential epitranscriptome and proteome modulation in the brain of neonatal mice exposed to isoflurane or sevoflurane.  Cell Biology and Toxicology  2022  Mar 6. doi: 10.1007/s10565-022-09701-9.  
    Xu Y, Jin MZ,, Jin WL. 2021   Microglia in neurodegenerative diseases. 高被引论文  Neural Regeneration Research  2021  Feb;16(2):270-280. 
    Qiu G, Wu Y,, Li L, Zhu X, Wang Y, Sun W, Dong H, Li Y, Hu J.  Dexmedetomidine Activation of Dopamine Neurons in the Ventral Tegmental Area Attenuates the Depth of Sedation in Mice.  Anesthesiology  2020  Anesthesiology. 2020 May 12.  
    , Lei Zhou, Qiong Meng, Hong Shi, Yuanhai Li   An appropriate level of autophagy reduces emulsified isoflurane-induced apoptosis in fetal neural stem cells  Neural Regeneration Research  2020  15(12):2278-2285. 
    Wang H,, Li X, Huang D, Yu S, He J, Li Y, Yan J.  Single-cell in vivo imaging of cellular circadian oscillators in zebrafish.  PLOS Biology  2020  Mar 13;18(3):e3000435.  
    Chen Y,, Wei L, Wang J, Xuan W, Wang Y, Li J, Ke Z, Li Y.  Yes associated protein protects and rescues SH?SY5Y cells from ketamine?induced apoptosis  Molecular Medicine Reports  2020  Sep;22(3):2342-2350.  
    Xiaoxue Hu, Yi Jin, Jiansong Li, Jiechen Xin,  Efficacy and safety of videolaryngoscopy versus direct laryngoscopy in paediatric intubation: A meta-analysis of 27 randomized controlled trials  Journal of Clinical Anesthesia  2020  S0952-8180(20)30592-4 
    Wu C, Chen X, Cai Y, Xia J, Zhou X, Xu S, Huang H, Zhang L, Zhou X, Du C, Zhang Y, Song J, Wang S, Chao Y,, Xu J, Zhou X, Chen D, Xiong W, Xu L, Zhou F, Jiang J, Bai C, Zheng J, Song Y.  Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China.热点论文  JAMA Internal Medicine  2020  Mar 13. doi: 10.1001/jamainternmed.2020.099 
    Zhong HY,, Zhang W, Cai S.  Effects of Adding Oxycodone to Ropivacaine on Labor Analgesia: A Randomized Controlled Trial.  Clin J Pain.  2020  Feb;36(2):96-100 
    Cai S, Zheng J, Meng Q, Chai J, Ma R, Wang Y, Zhang W,  Investigation of the Minimum Local Analgesic Concentration of Epidural Sufentanil Combined With Ropivacaine for Labor Analgesia.  Clin Ther.  2020  Jan;42(1):210-219. 
    Wang Y, An X, Zhang X, Liu J, Wang J,  Lithium chloride ameliorates cognition dysfunction induced by sevoflurane anesthesia in rats.  FEBS Open Bio  2019  2019 Dec 22. 
    Ji C, Ni Q, Chen W,, Ma D.  General anesthetic neurotoxicity in the young: Mechanism and prevention.  Neurosci Biobehav Rev.   2019  2019, Oct 10. pii: S0149-7634(19)30500-7. 
    , Lv J, Lu X, Li X, An X, Wang J, Weng H, Li Y.  Emulsified isoflurane induces release of cytochrome C in human neuroblastoma SHSY-5Y cells via JNK (c-Jun N-terminal kinases) signaling pathway.  Neurotoxicol Teratol.  2018  2018 Jan - Feb;65:19-25 
    , Lv J, Li X, Meng Q, Yang Q, Ma W, Li Y, Ke ZJ.  Sevoflurane decreases self-renewal capacity and causes c-Jun N-terminal kinase-mediated damage of rat fetal neural stem cells.  Sci Rep.  2017  2017 Apr 10;7:46304. doi: 10.1038/srep46304 
    Jiang J, Li S, Wang Y, Xiao X, Jin Y, Wang Y,, Yan S, Li Y.  Potential neurotoxicity of prenatal exposure to sevoflurane on offspring: Metabolomics investigation on neurodevelopment and underlying mechanism.  Int J Dev Neurosci.   2017  2017 Nov; 62:46-53 
    , Meng Q, Xu YH, Wang JW, Yu DS, Wei HF.  Supraglottic jet oxygenation and ventilation during colonoscopy under monitored anesthesia care: a controlled randomized clinical trial.  Eur Rev Med Pharmacol Sci.  2016  20(6):1168-73. 
    Zhao X,, Liang G, Wu Z, Peng Y, Joseph DJ, Inan S, Wei H.  Dual Effects of Isoflurane on Proliferation, Differentiation, and Survival in Human Neuroprogenitor Cells.  Anesthesiology.  2013  2013 Mar;118(3):537-549.