- 基本信息
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导师姓名：
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王群山
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学科代码：
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100201
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性别：
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男
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学科名称：
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内科学
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培养单位：
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附属新华医院
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三级学科
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心血管病
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导师类型：
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博士生导师
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专业领域名称：
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内科学 专业学位
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联系方式：
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mrqunshanwang@163.com；学术学位博士研究生；心脏电生理
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专业领域代码：
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105101
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邮编：
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200092
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邮箱地址：
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mrqunshanwang@163.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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国家卫计委心律失常介入诊治与左心耳封堵介入培训基地（培训导师）
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上海市医院综合评审专家库（评审专家）
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上海市医学会心血管病专科委员会（委员）、起搏电生理学组委员、心电学组（筹）组长
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中国房颤中心联盟左心耳封堵工作委员会全国副主任委员
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中华医学会心电生理与起搏分会中青年电生理工作委员会（全国副主任委员）
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上海交通大学医学院附属新华医院心血管科（行政副主任）
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荣获《医师报》主办的首届全国“中青年心律失常防治菁英（科学研究类）”荣誉
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教育部科技评价与评审信息系统专家库（评审专家）
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东方心脏病学会议心脏节律论坛（秘书长）
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《Journal of the Renin-Angiotensin-Aldosterone System》审稿人
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上海市医疗技术临床应用能力评估专家库（评审专家）
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上海市卫生计生系统文明委上海市房颤公益宣讲团（首批讲师）
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上海心律学会常委及心脏电生理学组副组长
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上海交通大学心律失常专病诊治中心（秘书长）
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中华医学会心脏起搏与电生理分会心电生理学组（全国委员）
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《中华心律失常杂志》通讯编委
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国家自然科学基金青年及面上项目（评审专家）
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《Pacing and Clinical Electrophysiology》审稿人
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中华医学会心脏起搏与电生理分会猝死防治工作委员会（全国委员）
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中国生物医学工程学会心律分会全国常委委员
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长城心脏病学大会学术委员兼左心耳封堵论坛坛主
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中华医学会心脏起搏与电生理分会左心耳封堵工作委员会（全国委员）
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中国博士后科学基金（评审专家）
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上海市中西医结合学会脑心同治专委会（副主任委员）
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中华医学会心脏起搏与电生理分会房颤工作委员会（全国委员）
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- 科研项目
| 82370316 | NDRG1调节心房肌细胞SERCA2a功能及其在房颤发病中的作用与机制研究 | 国自然面上项目 |
2024-01~2027-12
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49万元
| 课题负责人 |
| SHDC2022CRD044 | 基于人工智能的房颤早诊断新算法及房颤卒中预 防临床辅助决策系统的探索与转化研究 | 上海申康医院发展中心《促进市级医院临床技能与临床创新三年行动计划（2022-2024年）》示范性研究型病房建设以及研究型医师创新转化能力培训项目 |
2022-07~2024-09
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40万元
| 课题负责人 |
| 2021001 | 左心耳电隔离联合左心耳封堵一站式治疗持续性房颤前瞻性随机对照研究 | 广东省钟南山医学基金会 |
2021-01~2022-12
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50万元
| 课题负责人 |
| 2021005 | 新型心脏脉冲电场消融系统及导管的研发及应用 | 上海理工大学-上海交大医学院医工交叉重点支持项目 |
2021-01~2022-12
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20万元
| 课题负责人 |
| 91949127 | 染色质重塑相关蛋白EZH2调控心房肌细胞钙稳态与成纤维细胞分化在衰老伴发房颤中的作用和机制研究 | 国家自然科学基金重大研究计划 |
2020-01~2022-12
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68万元
| 课题负责人 |
| 81873485 | 核蛋白BRD4介导RNAPII停滞释放而调控心房电重构与结构重构在房颤发 | 国家自然科学基金面上项目 |
2019-01~2022-12
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57万元
| 课题负责人 |
| 17YJJ43 | Galectin-3基因在衰老相关房颤发病中的影响及其作用机制研究 | 新华医院院基金 |
2018-01~2020-12
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10万元
| 课题负责人 |
| 17411954600 | 建立一种多分子标记物联合的房颤早期诊断智能平台 | 上海市科委 |
2017-10~2020-09
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20万元
| 课题负责人 |
| 81270259 | 靶向心肌细胞骨架蛋白Yotiao 基因治疗房颤的机制研究 | 国家自然科学基金面上项目 |
2013-01~2016-12
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70万元
| 课题负责人 |
| 114119a8600 | 房颤发病机制与临床早期干预方法探讨 | 上海市科委 |
2011-01~2013-06
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10万元
| 课题负责人 |
| | 房颤相关KCNH2基因连锁的潜在功能SNP研究 | 新华医院院基金 |
2009-06~2011-05
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3万元
| 课题负责人 |
| 2006Y022 | 猪心梗后室速模型瘢痕识别和线性消融 | 上海市卫生局,青年基金 |
2007-01~2008-12
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2万元
| 课题负责人 |
- 学术论文
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Yuhan Chen, Xueze Jiang, Yuanyuan Chen, Yuchan Yuan, Sisi Wei, Ying Yu, Qing Zhou, Yi Yu, Hua Liu, Xuesheng Hua, Zhenwei Yang, Zhiyong Chen, Yigang Li,, Jie Chen, Yuepeng Wang
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Coptisine Inhibits Neointimal Hyperplasia through Attenuating PAK1/PAK2 Signaling in Vascular Smooth Muscle Cells without Retardation of Re-endothelialization
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Atherosclerosis
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2023
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minor revise
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Guojian Fang, Yingze Li, Jiali Yuan, Wei Cao, Shuai Song, Long Chen, Yuepeng Wang,
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Cadherin-11-Interleukin-6 Signaling between Cardiac Fibroblast and Cardiomyocyte Promotes Ventricular Remodeling in a Mouse Pressure Overload-Induced Heart Failure Model
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International Journal of Molecular Sciences
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2023
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2023, 24(7), 6549; https://doi.org/10.3390/ijms24076549
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Jiali Yuan, Hong Peng, Binfeng Mo, Chengye Yin, Guojian Fang, Yingze Li, Yuepeng Wang,Renhua Chen,
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Inhibition of Wdr5 Attenuates Ang-II-Induced Fibroblast-to-Myofibroblast Transition in Cardiac Fibrosis by Regulating Mdm2/P53/P21 Pathway
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biomolecules
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2022
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2022, 12, 1574. https://doi.org/10.3390/biom12111574
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Bin-Feng Mo1, Cheng-Qiang Wu2,, Yi-Gang Li1*
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Intrapericardial Thrombus Aspiration in Early Stage of Pericardial Thrombosis for Cardiac Tamponade Complicating Percutaneous Left Atrial Appendage Closure
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Frontiers in Cardiovascular Medicine
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2022
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DOI 10.3389/fcvm.2022.924570
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Yingze Li*, Guojian Fang*, Wei Cao*, Jiali Yuan*, Shuai Song, Hong Peng, Yuepeng Wang,
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Ezh2 Inhibits Replicative Senescence of Atrial Fibroblasts Through Promotion of H3K27me3 in the Promoter Regions of CDKN2a and Timp4 Genes
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Journal of Inflammation Research
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2022
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2022:15 4693–4708
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导管消融联合左心耳封堵一站式治疗心房颤动的临床应用
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中华心律失常学杂志
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2021
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2021;25（6）：498-503
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Bin-Feng Mo#, Yi Wan#, Abudushalamu Alimu, Jian Sun, Peng-Pai Zhang, Ying Yu, Mu Chen, Wei Li, Zhi-Quan Wang,, Yi-Gang Li
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Image Fusion of Integrating Fluoroscopy Into 3D Computed Tomography in Guidance of Left Atrial Appendage Closure
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European Heart Journal - Cardiovascular Imaging
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2021
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2021 Jan 1;22(1):92-101
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Bin-Feng Mo 1, Rui Zhang 1, Jia-Li Yuan 1, Jian Sun 1, Peng-Pai Zhang 1, Wei Li 1, Mu Chen 1, Xing-Xing Cai 1, Yi-Chi Yu 1,, Yi-Gang Li 1
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.Left Atrial Appendage Closure for Primary and Secondary Stroke Prevention in Patients With Hypertrophic Cardiomyopathy and Atrial Fibrillation
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Frontiers in Cardiovascular Medicine
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2021
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doi: 10.3389/fcvm.2021.719755
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Guojian Fang 1*,Wei Cao 1*, Long Chen 2*,Shuai Song 1, Yingze Li 1, Jiali Yuan 1, Yudong Fei 1, Zhuowang Ge 1, Yuhan Chen 1, Lei Zhou 3, Ying Xiao 1, Yi Wan 1, Yuepeng Wang 1,
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Foxm1 promotes TGF-β1-induced EndMT in endothelial cells through Smad2/3 and binds to the Snail promoter
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Journal of Cellular Physiology
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2021
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https://doi.org/10.1002/jcp.27583
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Wei Cao # 1, Shuai Song # 1, Guojian Fang # 1, Yingze Li 1, Yuepeng Wang 1,
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Cadherin-11 Deficiency Attenuates Ang-II-induced Atrial Fibrosis and Susceptibility to Atrial Fibrillation
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Journal of Inflammation Research
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2021
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2021 Jul 2;14:2897-2911
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Guojian Fang 1, Wei Cao 1, Long Chen 2, Shuai Song 1, Yingze Li 1, Jiali Yuan 1, Yudong Fei 1, Zhuowang Ge 1, Yuhan Chen 1, Lei Zhou 3, Ying Xiao 1, Yi Wan 1, Yuepeng Wang 1,
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Cadherin-11 deficiency mitigates high-fat diet-induced inflammatory atrial remodeling and vulnerability to atrial fibrillation
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Journal of Cellular Physiology
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2021
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2021 Aug;236(8):5725-5741
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Bin-Feng Mo, Jian Sun, Peng-Pai Zhang,, and Yi-Gang Li
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Transient Complete Left Bundle Branch Block During Left Fascicular Ventricular Tachycardia
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EP Europace
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2021
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2021 Sep 8;23(9):1349
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Jia-Li Yuan 1, Cheng-Ye Yin, Ying-Ze Li, Shuai Song, Guo-Jian Fang,
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EZH2 as an epigenetic regulator of cardiovascular development and diseases
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Journal of Cardiovascular Pharmacology
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2021
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2021 Aug 1;78(2):192-201
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Bin-Feng Mo,Ying Yu,,and Yi-Gang Li
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Deformation of left pulmonary vein ridge closely resembles device-related thrombus afterWatchman implantation
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European Heart Journal - Cardiovascular Imaging
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2020
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2020 Jul 1;21(7):819
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Bin-Feng Mo,Jian Sun,Peng-Pai Zhang,Wei Li,Mu Chen,Jia-Li Yuan,Yi Yu,,and Yi-Gang Li
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Combined Therapy of Catheter Ablation and Left Atrial Appendage Closure for Patients with Atrial Fibrillation: A Case-Control Study
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Journal of Interventional Cardiology
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2020
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2020 Jun 25;2020:8615410
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Bin-Feng Mo,Peng-Pai Zhang,Mu Chen,,Yi-Gang Li
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Complete atrioventricular block caused by pacing from proximal coronary sinus:What is the mechanism?
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Pacing Clin Electrophysiol
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2020
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2020 Mar;43(3):350-352
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,陈牧,孙健,张澎湃,李威,莫斌峰,郁怡,冯向飞,陆秋芬,李毅刚
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心房颤动导管消融联合左心耳封堵一站式 手术的可行性和围术期安全性分析
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中华心血管病杂志
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2020
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48(10): 842-847
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Shuai Song,Rui Zhang,Wei Cao,Guojian Fang,Yi Yu,Yi Wan,
Chuanhui Wang,Yigang Li,
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Foxm1 is a critical driver of TGF‐β‐induced EndMT in endothelial cells through Smad2/3 and binds to the Snail promoter
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Journal of Cellular Physiology(IF=4.522)
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2019
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2018:1-13
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Shuai Song, Rui Zhang, Binfeng Mo, Long Chen, Liang Liu, Yi
Yu, Wei Cao, Guojian Fang, Yi Wan, Yue Gu, Yuepeng Wang,
Yigang Li, Ying Yu,
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EZH2 as a novel therapeutic target for atrial fibrosis and atrial fibrillation
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Journal of Molecular and Cellular Cardiology(IF=5.68)
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2019
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2019 Aug 10;135:119-133
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Shuai Song,Liang Liu, Yi Yu, Rui Zhang, Yigang Li, Wei Cao, Ying Xiao, Guojian Fang,Zhen Li, Xuelian Wang, Qi Wang, Xin Zhao, Long Chen, Yuepeng Wang,
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Inhibition of BRD4 attenuates transverse aortic constriction- and TGF-β-induced endothelial-mesenchymal transition and cardiac fibrosis
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Journal of Molecular and Cellular Cardiology (IF=5.68)
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2019
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2019；127:83–96
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Yi Wan, Bin-Feng Mo, Arslan Salam, Jian Sun, Peng-Pai Zhang, Ying Yu, Mu Chen, Wei Li, Zhi-Quan Wang, Yi-Gang Li,
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Integration Of Fluoroscopy Into Multidetector Computed Tomography With Cartounivu For Left Atrial Appendage Occlusion Procedures.
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Heart Rhythm Annual Scientific Session 2019 Poster Presentation
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2019
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HRSPO03-033
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Shuai Song, Wei Cao, Guojian Fang, Yi Wan, Yue Gu,
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Brd4 As A Novel Therapeutic Target For Atrial Fibrosis And Atrial Fibrillation.
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Heart Rhythm Annual Scientific Session 2019 Poster Presentation
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2019
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HRSPO03-044
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, Jian Sun, Yi Yu, Pengpai Zhang, Yigang Li
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A Rare Cause For Refractory Cardiac Tamponade In A Patient After Atrial Fibrillation Ablation
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Heart Rhythm2018 Poster Presentation
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2018
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2018; May:B-PO02 -234 B-PO02 -234
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Tingfan Zhia,, Zuyun Liu, Yinsheng Zhu, Yong Wang, Rui Shi, Zhengdong Wang,Xuefeng Chu, Xiaofeng Wang and Xiaoyan Jiang
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Body mass index, waist circumference and waist-hip ratio are associated with depressive symptoms in older Chinese women: results from the Rugao Longevity and Ageing Study (RuLAS)
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Aging Ment Health
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2017
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2017 May;21(5):518-523
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, Peng-Pai Zhang, Da-Xin Zhou, Jian-Hua Yan, Jian Sun, Yi-Gang Li
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Successful retrieval of a broken circular mapping catheter after entrapment in the tricuspid valve apparatus
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Heart Rhythm Case Reports
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2016
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2016;2:187–189
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肖滢,
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心腔内超声在复杂性心律失常导管消融中的应用进展
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《中国心脏起搏与心电生理杂志》
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2016
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2016；6：543-546
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王传慧,郁怡,,孙健,冯向飞,刘博,张澎湃,王君,张睿,汪智全,李毅刚
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导管消融术联合心腔内电复律治疗非阵发性心房颤动的远期复发因素研究
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中国介入心脏病学杂志
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2016
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24（6）：301-304
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张源,
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达比加群酯在器质性心脏病心房颤动中的应用进展
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心血管病学进展
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2016
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37（1):27-31
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Liu Z1,, Zhi T, Zhu Y, Wang Y, Wang Z, Shi J, Xie X, Chu X, Wang X, Jiang X.
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Frailty Index and Its Relation to Falls and Overnight Hospitalizations in Elderly Chinese People: A Population-based Study
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J Nutr Health Aging(IF=2.996)
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2016
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2016;20(5):561-8
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王传慧,
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对心房颤动电复律治疗的认识
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中国介入心脏病学杂志
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2016
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24（4）：221-224
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Zhi TF, Sun XM, Li SJ,, Cai J, Li LZ, Li YX, Xu MJ, Wang Y, Chu XF, Wang ZD, Jiang XY
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Associations of sleep duration and sleep quality with life satisfaction in elderly Chinese: The mediating role of depression.
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Arch Gerontol Geriatr(IF=1.853)
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2016
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Jul-Aug;65:211-7
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李颖怡,
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心房颤动的生活质量评估和最新症状分级方法
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中国循环杂志
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2015
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30(7):708-710
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,汪智全,孙健,冯向飞,刘博,张澎湃,王君,张睿,李毅刚
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经导管射频消融术治疗心房颤动并发心脏压塞与HAS-BLED评分的相关性研究
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中国介入心脏病学杂志
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2015
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23(12):673-676
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, Hu X, Li S, Wang X, Wang J, Zhang R, Sun J, Zhang P, Feng X, Li YG.
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Association of the angiotensinogen M235T polymorphism with recurrence after catheter ablation of acquired atrial fibrillation
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Journal of the Renin-Angiotensin Aldosterone System (IF=2.400)
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2015
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16(4) 888 –897
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胡晓峰,,孙健,冯向飞,张澎湃,刘博,王君,张睿,李毅刚
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心房颤动患者CHADS2评分与导管消融术远期疗效的关系
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中华心血管病杂志
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2014
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42(5):1-6
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, Madhavan M, Viqar-Syed M, Asirvatham SJ.
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Successful ablation of a narrow complex tachycardia arising from a left ventricular false tendon: mapping and optimizing energy delivery.
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Heart Rhythm (IF=5.076)
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2014
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11(2):321-4.
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胡晓锋,
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线粒体与心房颤动
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国际心血管病杂志
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2013
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40(2)：65-68
|
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, Li YG, Chen XD, Yu JF, Wang J, Sun J, Lu SB, Jin L, Wang XF
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Angiotensinogen polymorphisms and acquired atrial fibrillation in Chinese
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J Electrocardiol (IF=1.36)
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2010
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2010;43(4):373-7
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, Samuel J. Asirvatham, Thomas M. Munger
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Eliminating premature ventricular complexes for ablation of polymorphic ventricular tachycardia and ventricular fibrillation
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Europace (IF=3.05)
|
2009
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2009 Feb;11(s1):4
|
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,XF WANG,XD CHEN, JF YU, J WANG, J SUN, SB LU, MY SHEN, M U,YG LI, L JIN
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Genetic Polymorphism of KCNH2 Confers Predisposition of Acquired Atrial Fibrillation in Chinese
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J Cardiovasc Electrophysiol (3.708)
|
2009
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2009; 20:1158-1162
|
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,李毅刚
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室速的治疗进展
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国际心血管病杂志
|
2007
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2007,34(4):227-232
|
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, Li YG, Lu SB, et al
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Clinical Application of Integrated Electroanatomical Mapping with Multislice CT Images In the Ablation of Atrial Fibrillation.
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Clinical Cardiology (IF=2.586)
|
2006
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2006Nov.29(S IV):136
|
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