- 基本信息
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导师姓名：
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钟捷
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学科代码：
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100201
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性别：
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男
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学科名称：
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内科学
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培养单位：
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附属瑞金医院
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三级学科
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消化系病
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导师类型：
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博士生导师
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专业领域名称：
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内科学 专业学位
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联系方式：
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专业领域代码：
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105101
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邮编：
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邮箱地址：
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jimmyzj64@medmail.com.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中华医学会全国小肠疾病学组委员
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中国癌症协会（CSCO）胃肠道间质瘤学组委员
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中华医学会消化道肿瘤协作组（小肠肿瘤组）成员
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中华医学会全国消化内镜学会委员
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上海炎症性肠病学组副组长
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上海消化内镜学会小肠镜学组副组长
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中华医学会消化病协会炎症性肠病学组委员
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- 科研项目
| 81970489 | 血小板P2RY12介导Sin1-mTORC2/Akt通路促进IBD进展的机制研究 | 国家自然科学基金 |
2020-01~2023-12
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57万元
| 课题负责人 |
| 81670503 | Vimentin及其磷酸化修饰促进克罗恩病发生发展的机制研究 | 国家自然科学基金 |
2017-01~2020-12
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58万元
| 课题负责人 |
| ZHYY-ZXYJHZX-201608 | 清肠栓联合水杨酸制剂SASP在溃疡性直肠炎诱导及维持缓解的疗效评价 | 上海市综合医院中西医结合专项项目 |
2016-12~2018-12
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10万元
| 课题负责人 |
| 13411950901 | 基于不同部位及基因突变特征的胃肠道间质瘤临床诊治方案的优化 | 上海市科委医学重点项目 |
2013-06~2016-09
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30万元
| 课题负责人 |
| | 制定小肠检查新技术(胶囊内镜、单或双气囊小肠镜、CT小肠重建)在炎症性肠病应用的规范 | 卫生行业科研专项项目 |
2011-09~2013-12
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0万元
| 子课题负责人 |
| | 溃疡性结肠炎癌变风险及监测 | 卫生行业科研专项项目 |
2011-09~2013-12
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0万元
| 子课题负责人 |
| | 英夫利昔单抗早期干预治疗中国汉族克罗恩病患者的疗效及对其肠粘膜修复影响 | 横向项目 |
2011-06~2014-12
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5万元
| 课题负责人 |
| | 舒尼替尼治疗分化良好的晚期胰腺NET的疗效及安全性评价 | 吴阶平癌症基金项目 |
2011-06~2014-12
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5万元
| 课题负责人 |
| 2007099 | 小肠GIST的规范性诊断流程的探索 | 上海市卫生局,局级课题 |
2008-01~2009-12
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3万元
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| 08YZ44 | 小肠间质瘤基因突变与预后的关系研究及分子标记物探索 | 上海市教委,发展基金 |
2008-01~2010-12
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8万元
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- 学术论文
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Juntao Sun,Tianyu Zhang,Mengmeng Cheng,Liwen Hong,Mengfan Xie,Peijun Sun,Rong Fan,Zhengting Wang,Lei Wang,
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TRIM29 facilitates the epithelial-to-mesenchymal transition and the progression of colorectal cancer via the activation of the Wnt/β-catenin signaling pathway
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Journal of Experimental & clinical Cancer Research
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2019
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38(104):1-15
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Maochen Zhang,Tianyu Zhang,Liwen Hong,Chen Zhang,Jie Zhou,Rong Fan,Lei Wang,Zhengting Wang,Bin Xu,
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Improvement of psychological status after infliximab treatment in patients with newly diagnosed Crohn’s disease
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Patient Preference and Adherence
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2018
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12:879-885
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Liwen Hong, Tianyu Zhang , Yun Lin, Rong Fan,Maochen Zhang,Mengmeng Cheng, Xiaolin Zhou , Juntao Sun, Peijun Sun, Qiangqiang Wu,Lei Wang, Zhengting Wang,
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Prognostic Analysis of Duodenal Gastrointestinal Stromal Tumors
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Gastroenterology Research and Practice
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2018
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2018：1-7
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Maochen Zhang,Tianyu Zhang,Liwen Hong,Qiangqiang Wu,Yun Lin,Mengfan Xie,Rong Fan,Zhengting Wang,Jie Zhou,
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Comparison of patients’tolerance between computed tomography enterography and double-balloon enteroscopy
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Patient Preference and Adherence
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2017
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11:1755-1766
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Maochen Zhang,Liwen Hong,Tianyu Zhang,Yun Lin,Sichang Zheng,Xiaolin Zhou,Rong Fan,Zhengting Wang,Chenli Zhang,
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Illness perceptions and stress: mediators between disease severity and psychological well-being and quality of life among patients with Crohn’s disease
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Patient Preference and Adherence
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2016
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10:2387-2396
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Shurong Hu, Mengmeng Chen, Yilin Wang, Zhengting Wang, Yaofei Pei,
Rong Fan, Xiqiang Liu, Lei Wang, Jie Zhou, Sichang Zheng, Tianyu Zhang,Yun Lin, Maochen Zhang, Ran Tao,
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mTOR Inhibition Attenuates Dextran Sulfate Sodium-Induced Colitis by Suppressing T Cell Proliferation and Balancing TH1/TH17/Treg Profile
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Plos One
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2016
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2016：1-19
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Tianyu Zhang, ZhengtingWang, Rong Fan, Maochen Zhang, Yun Lin, Liwen Hong, Xiaolin Zhou, Shurong Hu, Mengmeng Cheng,
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The Efficacy of Infliximab Monotherapy versus Infliximab-Azathioprine Sequential Treatment in Crohn’s Disease: Experience from a Tertiary Medical Center in China
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BioMed Research International
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2016
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2016:1-6
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Tian-Yu Zhang, Yun Lin, Rong Fan, Shu-Rong Hu, Meng-Meng Cheng, Mao-Chen Zhang, Li-Wen Hong,Xiao-Lin Zhou, Zheng-Ting Wang,
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Potential model for differential diagnosis between Crohn's disease and primary intestinal lymphoma
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World Journal of Gastroenterol
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2016
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22（42）：9411-9418
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Fan R,, Zheng S, Wang Z, Xu Y, Li S, Zhou J, Yuan F.
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microRNA-218 increase the sensitivity of gastrointestinal stromal tumor to imatinib through PI3K/AKT pathway.
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Clin Exp Med.
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2015
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15(2):137-44.
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Wang Z, Xu B, Zhang H, Fan R, Zhou J,
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Association between STAT3 gene Polymorphisms and Crohn's disease susceptibility: a case-control study in a Chinese Han population
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Diagn Pathol.
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2014
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29;9:104
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Fan R,, Wang ZT, Li SY, Zhou J, Tang YH..
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Evaluation of "top-down" treatment of early Crohn's disease by double balloon enteroscopy
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World J Gastroenterol.
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2014
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21;20(39):14479-87.
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Yu LF,, Cheng SD, Tang YH, Miao F.L
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ow-dose azathioprine effectively improves mucosal healing in Chinese patients with small bowel Crohn's disease.
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J Dig Dis.
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2014
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15(4):180-7.
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Wang L, Wang ZT, Zhang HX, Liu J, Lu SY, Fan R, Zhou J, Xia L, Sun YW,, Yuan YZ.
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Association between STAT3 gene polymorphisms and ulcerative colitis susceptibility: a case-control study in the Chinese Han population.
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Genet Mol Res.
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2014
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3;13(2):2343-8
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Wang L,WangZT, Hu JJ, Fan R, Zhou J,
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Polymorphisms of the vitamin D receptor gene and the risk of inflammatory bowel disease: a meta-analysis.
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Genet Mol Res.
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2014
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8;13(2):2598-610.
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Wang ZT, Hu JJ, Fan R, Zhou J,
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RAGE gene three polymorphisms with Crohn's disease susceptibility in Chinese Han population.
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World J Gastroenterol
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2014
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7;20(9):2397-402
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Fan R,, Zheng S, Wang Z, Xu Y, Li S, Zhou J, Yuan F.
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MicroRNA-218 inhibits gastrointestinal stromal tumor cell and invasion by targeting KIT.
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Tumour Biol.
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2014
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35(5):4209-17
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Hu JJ, Wang ZT,
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Lack of association between the interleukin 6 gene -174G>C polymorphism and colorectal cancer: evidence from a meta-analysis.
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Genet Mol Res.
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2013
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8;12(3):2205-14.
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Wang Z, Hu J, Fan R, Zhou J,
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Association between CD14 gene C-260T polymorphism and inflammatory bowel disease: a meta-analysis.
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PLoS One.
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2012
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2012;7(9):e45144.
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Wang Z, Hu J,
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Association between CD14 gene C-260T Meta-analysis of the NAD(P)H: quinine oxidoreductase 1 gene 609 C>T polymorphism with esophageal cancer risk.
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DNA Cell Biol.
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2012
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31(4):560-7.
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Zhang Y, Wang ZT,
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Lack of association between the 8-Meta-analysis demonstrates that the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene 609 C>T polymorphism is associated with increased gastric cancer risk in Asians.
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Genet Mol Res.
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2012
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13;11(3):2328-37.
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Fan R,, Wang ZT, Yu LF,Tang YH, Hu WG, Zhu YB, Jin XL.
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Prognostic factors and outcome of resected patients with gastrointestinal stromal tumors of small intestine.
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Med Oncol.
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2011
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28 Suppl 1:S185-8.
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Wang Z, Hu J, Cai W,
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Lack of association between the 8-oxoguanine DNA glycosylase gene Ser326Cys polymorphism and gastric cancer: evidence from a meta-analysis.
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Asian Pac J Cancer Prev.
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2011
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12(12):3427-31
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