基本信息

导师姓名：	葛盛芳	学科代码：	100212
性别：	男	学科名称：	眼科学
培养单位：	附属第九人民医院	三级学科
导师类型：	博士生导师	专业领域名称：
联系方式：	geshengfang@hotmail.com 021-53314247	专业领域代码：
邮编：	200011	邮箱地址：	geshengfang@hotmail.com

研究方向 (点击浏览详细信息)


眼恶性肿瘤发生机制及其靶向治疗

社会任职


中国生物物理学会辐射与环境专业委员会常务委员
上海市眼眶病眼肿瘤重点实验室副主任
上海法院知识产权技术咨询专家
曾兼任上海市生物化学与分子生物学学会理事。任<转化医学杂志>编委，《上海交通大学学报（医学版）》审稿人。
教育部学位与研究生教育发展中心评审专家

科研项目

项目编号	项目名称	课题来源	起止年月	批准经费	承担职责
12275178	药物清除放射诱导的衰老细胞提高葡萄膜黑色素瘤辐射效应的机制研究	国家自然科学基金项目	2023-01~2026-12	56万元	课题负责人
U1932135	富氧碳基纳米材料协同重离子放疗杀伤肿瘤的作用及机理研究	国家自然科学基金项目	2020-01~2023-12	60万元	课题负责人
81772875	LncRNA L12–PTPRZ1通路在葡萄膜黑色素瘤靶向治疗中的作用机理研究	国家自然科学基金项目	2018-01~2021-12	55万元	课题负责人
U1432117	lncRNA-29314916-CCNB2通路在重离子放疗中的辐射增敏机理研究	国家自然科学基金项目	2015-01~2017-12	68万元	课题负责人
201402014	常见眼恶性肿瘤诊疗新技术、规范及其应用研究	国家卫计委公益性行业科研专项项目	2014-06~2017-06	1262万元	课题参与人
13JC1406202	lncRNA-15:23930854通过调控有关蛋白参与低氧诱导的癌细胞恶性转化过程	上海市基础研究重点	2013-09~2016-08	30万元	课题负责人
XDA01040411	肿瘤干细胞分离、鉴定及特异标记物的研究及基于肿瘤干细胞特征的靶向药物研究	中国科学院战略性先导科技专项资助A类	2013-01~2017-12	200万元	课题参与人
81172323	导入PRC2基因修复肿瘤细胞IGF2遗传印迹丢失的作用及其机制研究	国家自然科学基金项目	2012-01~2015-12	64万元	课题负责人
10979034	重离子协同腺病毒载体靶向杀灭肿瘤细胞的机理研究	国家自然科学基金项目	2010-01~2012-12	54万元	课题负责人
2010CB529902	靶向基因治疗的应用基础研究	973计划	2010-01~2014-12	144万元	课题参与人
091024851	基因-MicroRNA共表达新型腺病毒对荷瘤鼠肿瘤生长的影响	第三期国家大学生创新性实验计划项目	2009-11~2011-06	3万元	课题负责人
09ZZ110	基因－小干扰RNA共表达肿瘤基因治疗新策略的研究	上海市教委	2009-01~2011-12	15万元	课题负责人
08ZR1412500	基因－小干扰RNA共表达策略在肿瘤基因治疗中的应用研究	上海市科委	2008-11~2010-12	10万元	课题负责人
ZD0702	Trail-siPROM1共表达双靶点胃肠肿瘤干细胞基因治疗新策略研究	仁济医院合作研究项目	2007-10~2010-09	25万元	课题负责人

学术论文

作者	论文标题	期刊名	出版年	卷期页码
Fu Y, Yu J, Li F, Ge S. （通讯作者）	Oncometabolites drive tumorigenesis by enhancing protein acylation: from chromosomal remodelling to nonhistone modification.	J Exp Clin Cancer Res（IF 12.658 ）	2022	41(1):144
Yao Y, Gu X, Xu X, Ge S （通讯作者）, Jia R	Novel insights into RB1 mutation	Cancer letters (IF 9.756)	2022	547:215870
Chai P, Jia R, Li Y, Zhou C, Gu X, Yang L, Shi H, Tian H, Lin H, Yu J, Zhuang A, Ge S, Jia R, Fan X.	Regulation of epigenetic homeostasis in uveal melanoma and retinoblastoma.	Prog Retin Eye Res（IF19.704）	2022	89:101030
Jia S, Zhu T, Shi H, Zong C, Bao Y, Wen X, Ge S, Ruan J, Xu S, Jia R, Fan X.	American Joint Committee on Cancer Tumor Staging System Predicts the Outcome and Metastasis Pattern in Conjunctival Melanoma.	Ophthalmology（IF14.277）	2022	129(7):771-780.
Tian H, Shi H, Yu J, Ge S （通讯作者）, Ruan J	Biophysics Role and Biomimetic Culture Systems of ECM Stiffness in Cancer EMT	Global challenges (IF 5.135)	2022	6(6):2100094
Huang Y, Zhang L, Ji Y, Deng H, Long M, Ge S, Su Y, Chan SY, Loh XJ, Zhuang A, Ruan J	A non-invasive smart scaffold for bone repair and monitoring.	Bioactive materials (IF 16.874)	2022	19:499-510
Yu J, Chai P, Xie M, Ge S, Ruan J, Fan X, Jia R	Histone lactylation drives oncogenesis by facilitating m6A reader protein YTHDF2 expression in ocular melanoma.	Genome biology (IF 17.906)	2021	22(1):85
Lin H, Yu J, Gu X, Ge S （通讯作者）, Fan X	Novel insights into exosomal circular RNAs: Redefining intercellular communication in cancer biology.	Clinical and translational medicine (IF 8.554)	2021	11(12):e636
Yang L, Gu X, Yu J, Ge S （通讯作者）, Fan X.	Oncolytic Virotherapy: From Bench to Bedside	Frontiers in cell and developmental biology (IF 6.081)	2021	9:790150
Wang S, Chen B, Ouyang L, Wang D, Tan J, Qiao Y, Ge S, Ruan J, Zhuang A, Liu X, Jia R	A Novel Stimuli-Responsive Injectable Antibacterial Hydrogel to Achieve Synergetic Photothermal/Gene-Targeted Therapy towards Uveal Melanoma.	Advanced science (IF 17.521)	2021	8(18):e2004721
Chai P, Yu J, Wang X, Ge S （通讯作者）, Jia R	BMP9 promotes cutaneous wound healing by activating Smad1/5 signaling pathways and cytoskeleton remodeling.	Clinical and translational medicine (IF 8.554)	2021	11(1):e271
Gu X, Xie M, Jia R, Ge S （通讯作者）	Publication Trends of Research on Retinoblastoma During 2001-2021: A 20-Year Bibliometric Analysis.	Frontiers in medicine (IF 5.058)	2021	8:675703
Ding Y, Yu J, Chen X, Wang S, Tu Z, Shen G, Wang H, Jia R, Ge S, Ruan J, Leong KW, Fan X	Dose-Dependent Carbon-Dot-Induced ROS Promote Uveal Melanoma Cell Tumorigenicity via Activation of mTOR Signaling and Glutamine Metabolism.	Advanced science (IF17.521)	2021	8(8):2002404
Li P, He J, Yang Z, Ge S, Zhang H, Zhong Q, Fan X	ZNNT1 long noncoding RNA induces autophagy to inhibit tumorigenesis of uveal melanoma by regulating key autophagy gene expression.	Autophagy (IF 13.391)	2020	16(7), 1186–1199
Fan J, Xu Y, Wen X, Ge S, Jia R, Zhang H, Fan X	A Cohesin-Mediated Intrachromosomal Loop Drives Oncogenic ROR lncRNA to Accelerate Tumorigenesis.	Molecular therapy : the journal of the American Society of Gene Therapy (IF 12.910)	2020	27(12), 2182–2194
Wen X, Wang H, Chai P, Fan J, Zhang X, Ding T, Jia R, Ge S （通讯作者）, Zhang H, Fan X	An Artificial CTCF Peptide Triggers Efficient Therapeutic Efficacy in Ocular Melanoma.	Molecular therapy oncolytics (IF 6.311)	2020	18:317-325
Liu T, Zhang H, Fang J, Yang Z, Chen R, Wang Y, Zhao X, Ge S （通讯作者）, Yu J, Huang J	AGO2 phosphorylation by c-Src kinase promotes tumorigenesis.	Neoplasia (IF 6.218)	2020	22(3):129-141
Yu J, Loh XJ, Luo Y, Ge S （通讯作者）, Fan X, Ruan J	Insights into the epigenetic effects of nanomaterials on cells.	Biomaterials science (IF 7.590)	2020	8(3), 763–775
Chai P, Yu J, Ge S （通讯作者）, Jia R, Fan X	Genetic alteration, RNA expression, and DNA methylation profiling of coronavirus disease 2019 (COVID-19) receptor ACE2 in malignancies: a pan-cancer analysis.	Journal of hematology & oncology (IF 23.168)	2020	13(1):43
Wang H, Yang J, Pan H, Tai MC, Maher MH, Jia R, Ge S （通讯作者）, Lu L	Dinutuximab Synergistically Enhances the Cytotoxicity of Natural Killer Cells to Retinoblastoma Through the Perforin-Granzyme B Pathway.	OncoTargets and therapy (IF 4.345)	2020	13:3903-3920
Li F, Xu Y, Xu X, Ge S, Zhang F, Zhang H, Fan X	lncRNA HotairM1 Depletion Promotes Self-Renewal of Cancer Stem Cells through HOXA1-Nanog Regulation Loop.	Molecular therapy. Nucleic acids (IF 10.183)	2020	22:456-470
Gu X, Yu J, Chai P, Ge S （通讯作者）, Fan X	Novel insights into extrachromosomal DNA: redefining the onco-drivers of tumor progression.	Journal of experimental & clinical cancer research : CR (IF 12.658)	2020	39(1):215
Ding X, Cao Y, Xing Y, Ge S （通讯作者）, Lin M, Li J	TIMP-1 Mediates Inflammatory and Immune Response to IL-6 in Adult Orbital Xanthogranulomatous Disease.	Ocular immunology and inflammation (IF 3.728)	2020	28(2), 288–297
Chai P, Yu J, Ge S* （通讯作者）, Jia R, Fan X.	Genetic alteration, RNA expression, and DNA methylation profiling of coronavirus disease 2019 (COVID-19) receptor ACE2 in malignancies: a pan-cancer analysis.	J Hematol Oncol (IF 23.168)	2020	13(1):43
Xie M, Yu J, Ge S （通讯作者）, Huang J, Fan X	SUMOylation homeostasis in tumorigenesis.	Cancer letters (IF 9.756)	2020	469:301-309
Ji Y, Zhou Y, Shen Q, Xu W, Ge S （通讯作者）, Gu L, Fan X	Prediction of late displacement of the globe in orbital blowout fractures.	Acta ophthalmologica (IF 3.988)	2020	98(2), e197–e202
He X, Chai P, Li F, Zhang L, Zhou C, Yuan X, Li Y, Yang J, Luo Y, Ge S, Zhang H, Jia R, Fan X	A novel LncRNA transcript, RBAT1, accelerates tumorigenesis through interacting with HNRNPL and cis-activating E2F3.	Molecular cancer (IF 41.444)	2020	19(1):115
Chai P, Yu J, Jia R, Wen X, Ding T, Zhang X, Ni H, Jia R, Ge S （通讯作者）, Zhang H, Fan X	Generation of onco-enhancer enhances chromosomal remodeling and accelerates tumorigenesis.	Nucleic acids research (IF 19.160)	2020	48(21):12135-12150
Li Y, He J, Qiu C, Shang Q, Qian G, Fan X, Ge S （通讯作者）, Jia R*.	The oncolytic virus H101 combined with GNAQ siRNA-mediated knockdown reduces uveal melanoma cell viability.	J Cell Biochem. (IF 4.480)	2019	120(4):5766-5776.
Chen J, Li F, Xu Y, Zhang W, Hu Y, Fu Y, Xu W, Ge S （通讯作者）, Fan X, Lu L	Cholesterol modification of SDF-1-specific siRNA enables therapeutic targeting of angiogenesis through Akt pathway inhibition.	Experimental eye research (IF 3.770)	2019	184:64-71
Ding Y, Yang J, Ma Y, Yao T, Chen X, Ge S （通讯作者）, Wang L, Fan X	MYCN and PRC1 cooperatively repress docosahexaenoic acid synthesis in neuroblastoma via ELOVL2.	Journal of experimental & clinical cancer research : CR (IF 12.658)	2019	38(1), 498
Jia R, Chai P, Wang S, Sun B, Xu Y, Yang Y, Ge S, Jia R, Yang YG, Fan X	m6A modification suppresses ocular melanoma through modulating HINT2 mRNA translation.	Molecular cancer (IF 41.444)	2019	18(1), 161
Shang Q, Li Y, Wang H, Ge S （通讯作者）, Jia R.	Altered expression profile of circular RNAs in conjunctival melanoma.	Epigenomics. (4.357)	2019	11(7):787-804.
Zhao H, Pan H, Wang H, Chai P, Ge S （通讯作者）, Jia R, Fan X.	SKP2 targeted inhibition suppresses human uveal melanoma progression by blocking ubiquitylation of p27.	Onco Targets Ther. (IF 4.345)	2019	12:4297-4308
Shang Q, Yang Z, Jia R, Ge S （通讯作者）	The novel roles of circRNAs in human cancer.	Mol Cancer (IF 41.444)	2019	18(1):6
Yang Z, Gu Q, Wang Y, Liu B, Zhou G, Shao C, Ruan J, Jia R, Ge S （通讯作者）	Heavy-Ion Carbon Radiation Regulates Long Non-Coding RNAs in Cervical Cancer HeLa Cells.	Journal of Cancer (IF 4.478)	2019	10(21), 5022–5030
Chai P, Jia R, Jia R, Pan H, Wang S, Ni H, Wang H, Zhou C, Shi Y, Ge S, Zhang H, Fan X.	Dynamic chromosomal tuning of a novel GAU1 lncing driver at chr12p13.32 accelerates tumorigenesis.	Nucleic Acids Res(IF 19.160)	2018	46(12):6041-6056
Li Y, Shang Q, Li P, Cao J, Zhu L, Jager MJ, Fan X, Ge S, Jia R	Characterization of a conjunctival melanoma cell line CM-AS16, newly-established from a metastatic Han Chinese patient.	Exp Eye Res (IF 3.770)	2018	173:51-63
Ruan J, Wang Y, Li F, Jia R, Zhou G, Shao C, Zhu L, Cui M, Yang DP, Ge S. （通讯作者）	Graphene Quantum Dots for Radiotherapy.	ACS Appl Mater Interfaces.(IF10.383)	2018	10(17):14342-14355
Li P, Li Y, Zhu L, Yang Z, He J, Wang L, Shang Q, Pan H, Wang H, Ma X, Li B, Fan X, Ge S* （通讯作者）, Jia R, Zhang H.	Targeting secreted cytokine BMP9 gates the attenuation of hepatic fibrosis.	Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (IF 6.633)	2017	864(3):709-720
Li G, Wang L, Jiang Y, Kong X, Fan Q, Ge S, Hao Y.	Upregulation of Akt signaling enhances femoral fracture healing by accelerating atrophic quadriceps recovery.	Biochim Biophys Acta	2017	1863(11):2848-2861
Li Y, Jia R, Ge S （通讯作者）	Role of Epigenetics in Uveal Melanoma.	Int J Mol Med (IF 5.314)	2017	40(4):979-986
Bi J, Li P, Li C, He J, Wang Y, Zhang H, Fan X, Jia R, Ge S （通讯作者）	The SDF-1/CXCR4 chemokine axis in uveal melanoma cell proliferation and migration	Tumour Biol	2016	37(3):4175-82
Zhang L, Jia R, Zhao J, Fan J, Zhou Y, Han B, Song X, Wu L, Zhang H, Song H, Ge S* （通讯作者）, Fan X*	Novel mutations in the RB1 gene from Chinese families with a history of retinoblastoma	Tumour Biol.	2015	36(4):2409-20
Pan H, Jia R, Zhang L, Xu S, Wu Q, Song X, Zhang H, Ge S* （通讯作者）, Xu XL, Fan X	BAP1 regulates cell cycle progression through E2F1 target genes and mediates transcriptional silencing via H2A monoubiquitination in uveal melanoma cells.	Int J Biochem Cell Biol (5.652)	2015	60(3):176-84
Fan J, Xing Y, Wen X, Jia R, Ni H, He J, Ding X, Pan H, Qian G, Ge S （通讯作者）, Hoffman AR, Zhang H, Fan X	Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis	Genome Biol (IF 17.906)	2015	16(1):139-156
Bi J, Ge S （通讯作者）	Potential roles of BMP9 in liver fibrosis	Int J Mol Sci (IF 6.208)	2014	15(11):20656-67
Zhang H, Zeitz MJ, Wang H, Niu B, Ge S, Li W, Cui J, Wang G, Qian G, Higgins MJ, Fan X, Hoffman AR, Hu JF.	Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus	J Cell Biol (IF8.077)	2014	204(1):61-75
Jia R, Xu S, Huang X, Song X, Pan H, Zhang L, He F, Lin M, Ge S* （通讯作者）, Fan X*.	Pingyangmycin as First-Line Treatment for Low-Flow Orbital or Periorbital Venous Malformations: Evaluation of 33 Consecutive Patients	JAMA Ophthalmol (IF 8.253)	2014	132(8):942-8
Wang J, Jia R, Zhang Y, Xu X, Song X, Zhou Y, Zhang H, Ge S* （通讯作者）, Fan X*.	The role of Bax and Bcl-2 in gemcitabine-mediated cytotoxicity in uveal melanoma cells	Tumour Biol	2014	35(2):1169-75
Ye L, Zhao X, Lu J, Qian G, Zheng JC, Ge S. （通讯作者）	Knockdown of TIGAR by RNA interference induces apoptosis and autophagy in HepG2 hepatocellular carcinoma cells.	Biochem Biophys Res Commun (IF 3.322)	2013	436(9):1-6
Zhang H, Jiao W, Sun L, Fan J, Chen M, Wang H, Xu X, Shen A, Li T, Niu B, Ge S, Li W, Cui J, Wang G, Sun J, Fan X, Hu X, Mrsny RJ, Hoffman AR, Hu JF	Intrachromosomal Looping Is Required for Activation of Endogenous Pluripotency Genes during Reprogramming	Cell Stem Cell (IF25.269)	2013	13(1):30-5
Cun B, Song X, Jia R, Wang H, Zhao X, Liu B, Ge S （通讯作者）, Fan X	Cell growth inhibition in HPV 18 positive uveal melanoma cells by E6/E7 siRNA	Tumour Biol	2013	34(3):1801-6
Zhang Y, Jia R, Wang J, Xu X, Yao Y, Ge S* （通讯作者）, Fan X*	Targeted Silencing of MART-1 Gene Expression by RNA Interference Enhances the Migration Ability of Uveal Melanoma Cells	Int. J. Mol. Sci (IF 6.208)	2013	14(4):15092-15104
Li C, Chen P, Zhang J, Zhang L, Huang X, Yao Y, Che X, Fan X, Ge S （通讯作者）, Wang Z.	Enzyme-induced vitreolysis can alleviate the progression of diabetic retinopathy through the HIF-1α pathway.	Invest Ophthalmol Vis Sci (IF 4.925)	2013	54(12):1-12
Li C, Wu Q, Liu B, Yao Y, Chen Y, Zhang H, Wang C, Cao J, Ge S （通讯作者）	Detection and Validation of Circulating Endothelial Cells, a Blood-based Diagnostic Marker of Acute Myocardial Infarction	PLoS ONE (IF 3.752)	2013	8(3):58478-0
Zhang J, Sun Q, Zhang Z, Ge S, Han ZG, Chen WT	Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop	Oncogene (IF 8.756)	2012	32(1):61-69
Hao Y, Ma Y, Wang X, Jin F, Ge S.	Short-term muscle atrophy caused by botulinum toxin-A local injection impairs fracture healing in the rat femur.	J Orthop Res (IF 3.102)	2012	30(4):574-80
Xin Song, Haibo Wang, Renbing Jia, Biyun Cun, Xiaoping Zhao, Yixiong Zhou, Xiaofang Xu, Guanxiang Qian, Shengfang Ge and Xianqun Fan （通讯作者）	Combined treatment with an oncolytic adenovirus and vincristine antitumor activity against retinoblastoma cells	Int. J. Mol. Sci. (IF 6.208)	2012	13(0):10736-10749
Wang H, Song X, Zhang H, Zhang J, Shen X, Zhou Y, Fan X, Dai L, Qian G, Hoffman AR, Hu JF, Ge S （通讯作者）	Potentiation of tumor radiotherapy by a radiation-inducible oncolytic and oncoapoptotic adenovirus in cervical cancer xenografts	Int J Cancer(IF 7.316)	2012	15;130 (2):443-53
Sun J, Zhou J, Zhao P, Lian J, Zhu H, Zhou Y, Sun Y, Wang Y, Zhao L, Wei Y, Wang L, Cun B, Ge S, Fan X	High Prevalence of Myopia and High Myopia in 5060 Chinese University Students in Shanghai	Invest Ophthalmol Vis Sci. (IF 4.925)	2012	53(12):7504-9
Huang X, Jia R, Zhao X, Liu B, Wang H, Wang J, Zhou Y, Cun B, Ge S （通讯作者）, Fan X.	Recombinant oncolytic adenovirus H101 combined with siBCL2: cytotoxic effect on uveal melanoma cell lines	Br J Ophthalmol (IF 5.908)	2012	96(10):1331-8
Wang Z, Jia R, Ge S, He T, Zhang Y, Yang Y, Wang Y, Shi W, Ji Y, Ye F, Chen P, Lu J, Sun J, Xu X, Zhou Y, Gu P, Luo M, Lu H, Fan X	Ocular Complications of Human Immunodeficiency Virus Infection in Eastern China	Am J Ophthalmol (IF 5.488)	2012	153(2):363-369
Cun B, Song X, Jia R, Zhao X, Wang H, Ge S, Fan X	Combination of oncolytic adenovirus and dacarbazine enhances antitumor ability against uveal melanoma cells via cell cycle block	Cancer Biology & Therapy (IF 4.875)	2012	13(2):77-84
Guo H, Hu X, Ge S, Qian G, Zhang J	Regulation of RAP1B by miR-139 suppresses human colorectal carcinoma cell proliferation	Int J Biochem Cell Biol (IF 5.652)	2012	44(9):1465-72
Huang X, Wang L, Zhang H, Wang H, Zhao X, Qian G, Hu J, Ge S （通讯作者）, Fan X	Therapeutic efficacy by targeting correction of notch1-induced aberrants in uveal tumors	PLoS ONE (IF 3.752)	2012	7(8):44301-0
Yao Y, Wang L, Zhang H, Wang H, Zhao X, Zhang Y, Zhang L, Fan X, Qian G, Hu J, Ge S （通讯作者）	A Novel Anticancer Therapy That Simultaneously Targets Aberrant p53 and Notch Activities in Tumors	PLoS ONE (IF 3.752)	2012	7(10):46627-0
Fan J, Zhou Y, Huang X, Zhang L, Yao Y, Song X, Chen J, Hu J, Ge S, Song H, Fan X.	The combination of polyalanine expansion mutation and a novel missense substitution in transcription factor FOXL2 leads to different ovarian phenotypes in blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) patients.	Hum Reprod (IF 6.353)	2012	27(11):3347-57
Zhang H, Niu B, Hu JF, Ge S, Wang H, Li T, Ling J, Steelman BN, Qian G, Hoffman AR.	Interruption of intrachromosomal looping by CTCF decoy proteins abrogates genomic imprinting of human insulin-like growth factor II	Journal of Cell biology (IF 8.077)	2011	193(3):475-87
Zhang J, Guo H, Zhang H, Wang H, Qian G, Fan X, Hoffman AR, Hu JF, Ge S （通讯作者）	Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene Friend leukemia virus integration 1.	Cancer (IF 6.921)	2011	117(1):86-95
Xu H, Ni P, Chen C, Yao Y, Zhao X, Qian G, Fan X, Ge S （通讯作者）	SP1 suppresses phorbol 12-myristate 13-acetate induced up-regulation of human regucalcin expression in liver cancer cells.	Mol Cell Biochem (IF 3.842)	2011	355(1):9-15
Song X, Zhou Y, Jia R, Xu X, Wang H, Hu J, Ge S, Fan X	Inhibition of retinoblastoma in vitro and in vivo with conditionally replicating oncolytic adenovirus H101.	Investigative Ophthalmology and Vision Science(IF 4.925)	2010	51(5):2626-35
Zhang P, Ying L, Xu R, Ge S （通讯作者）, Mei W, Li F, Dai B, Lu J, Qian G	Tumor-Specific, Hypoxia-Regulated WWOX Expression Adenovirus Inhibits Human Non-Small Cell Lung Cancer Growth in Vivo.	Human Gene Therapy (IF 4.793)	2010	21(1):27-39
Zhang J, Huang S, Zhang H, Wang H, Guo H, Qian G, Fan X, Lu J, Hoffman AR, Hu JF, Ge S （通讯作者）	Targeted knockdown of Bcl2 in tumor cells using a synthetic TRAIL 3’-UTR microRNA.	Int J Cancer (IF 7.316)	2010	126(9):2229-2239
Zhang J, Guo H, Qian G, Ge S, Ji H, Hu X, Chen W.	MiR-145, a new regulator of the DNA Fragmentation Factor-45 (DFF45)-mediated apoptotic network	Mol Cancer(IF 41.444)	2010	9(1):211-220
Zhou Y, Song X, Jia R, Wang H, Dai L, Xu X, Gu P, Ge S （通讯作者）, Fan X	Radiation-inducible human tumor necrosis factor-related apoptosis inducing ligand (TRAIL) gene therapy：a novel treatment for radioresistant uveal melanoma.	Pigment Cell & Melanoma Research(IF 4.159)	2010	23:661-674
Zhang H, Wang H, Zhang J, Qian G, Niu B, Fan X, Lu J, Hoffman AR, Hu JF, Ge S （通讯作者）	Enhanced Therapeutic Efficacy by Simultaneously Targeting Two Genetic Defects in Tumors.	Mol Ther(IF 12.910)	2009	17 (1):57-64
Zhang X, Mei W, Zhang L, Yu H, Zhao X, Fan X, Qian G, Ge S （通讯作者）	Co-expression of P1A35-43/β2m fusion protein and co-stimulatory molecule CD80 elicits effective anti-tumor immunity in the P815 mouse mastocytoma tumor model.	Oncol Rep. (IF 4.136)	2009	22（5）:1213-1220
Fang L, Wang K, Liu X, Zhang L, Zhang X, Qian L, Lu J, Qian G, Ge S （通讯作者）	A Study on the Anti-Tumor Immunity Induced by Gene-Modified Melanoma B16 Cells.	Oncol Rep. (IF 4.136)	2008	19(6):1589-95
Zhao X, Wang L, Sun Y, Ye L, Lu J, Yuan Y, Qian G, Ge S （通讯作者）	The endoplasmic reticulum (ER)-target protein Bik induces Hep3B cells apoptosis by the depletion of the ER Ca(2+) stores.	Mol Cell Biochem. (IF 3.842)	2008	312(1-2):33-8
Zhao X, Sun Y, Yu H, Ye L, Zhang L, Lu J, Yuan Y, Qian G, Ge S （通讯作者）	Apoptosis induced by BIK was decreased with RNA interference of caspase-12.	Biochem Biophys Res Commun. (IF 3.322)	2007	359(4):896-901.
X. Liu, L. Zhang, X. Zhang, H. Yu, X. Zhao, J. Lu, G. Qian ,S. Ge （通讯作者）	The effect of co-expression costimulatory molecule CD80 on uptake of antigen peptide-MHC class I-GFP complex by specific T cells.	Int J Oncol. (IF 5.884)	2007	30（6）:1389-1396
Yu H, Zhao X, Huang S, Lu J, Qian G, Ge S （通讯作者）	Blocking Notch1 Signaling by RNA Interference can Induce Growth Inhibition in Hela Cells.	Int J Gynecol Cancer. (IF 4.661)	2007	17(2):511-6.
Jia RB, Zhang P, Zhou YX, Song X, Liu HY, Wang LZ, Luo M, Lu J, Ge SF （通讯作者）, Fan XQ.	VEGF-Targeted RNA Interference Suppresses Angiogenesis and Tumor Growth of Retinoblastoma.	Ophthalmic Res. (IF 3.031)	2007	39(2):108-115.