• 基本信息
    导师姓名： 牟姗 学科代码： 100201
    性别： 女 学科名称： 内科学
    培养单位： 附属仁济医院 三级学科 肾病
    导师类型： 博士生导师 专业领域名称： 内科学 专业学位
    联系方式： 上海市浦东新区浦建路160号 专业领域代码： 105101
    邮编： 200127 邮箱地址： shan_mou@126.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    上海中西医结合学会肾病专业委员会副主任委员兼秘书
    中国中西医结合学会肾病青年委员会副主任委员
    中华中医药学会肾病分会委员
    上海市浦东新区医学会肾内科专委会主任委员
    上海市医学会肾病分会副主任委员
    上海市医师协会中西医结合科医师分会副会长
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    81970574SENP1调控CD4+T细胞分化及在缺血再灌注肾损伤中的作用及机制国家自然基金面上项目 2020-01~2023-12 55万元  课题负责人
    81770668SENP1通过HIF1α调控巨噬细胞极化在缺血再灌注肾损伤中的作用及机制国家自然基金面上项目 2018-01~2021-12 55万元  课题负责人
    16XD1401900基于KIM-1调控巨噬细胞 功 能探索黄芪防治急性肾损伤后肾纤维化的机制研究上海市科技委员会上海市优秀学术带头人 2016-05~2019-04 40万元  课题负责人
    81573748黄芪甲苷调控Th17和Treg细胞分化防治肾损伤的机制研究国家自然基金面上项目 2016-01~2019-12 68.4万元  课题负责人
    14140903200急性肾损伤后肾纤维化小鼠模型的构建研究上海市科委项目资助 2014-07~2016-06 40万元  课题负责人
    2014DFT30090急性肾损伤防治的超声集成技术评价体系的建立和应用港澳台科技合作专项项目 2014-04~2017-04 100万元  课题负责人
    81373865基于内源性KIM-1/TIM-4 通路探讨黄芪甲苷防治肾纤维化的机制国家自然基金面上项目 2014-01~2017-12 73万元  课题负责人
    12401906400益气通络法防治急性肾损伤后肾脏纤维化的前瞻性研究上海市科委中医引领项目 2012-10~2015-09 10万元  课题负责人
    81102700从黄芪干预肾纤维化的分子机制探讨“久病入络”的理论基础国家自然基金 2012-01~2014-12 25万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Yao Xu, Xiao Dong Yuan, Jia Jin Wu, Ruo Yang Chen, Lei Xia, Ming Zhang, Cong Hui Han,  The N6-methyladenosine mRNA Methylase METTL14 Promotes Renal Ischemic Reperfusion Injury via Suppressing YAP1  J Cell Biochem  2020  121 (1), 524-533 
    Tian L, Shao X,Xie Y,Wang Q,Che X, Zhang M, Xu W, Xu Y, Ni Z,  Kidney Injury Molecule-1 is Elevated in Nephropathy and Mediates Macrophage Activation via the Mapk Signalling Pathway  Cell Physiol Biochem  2017  41 2 769~783 
    Wei Yan, Yao Xu, Yanhong Yuan, Lei Tian, Qin Wang, Yuanyuan Xie, Xinghua Shao, Ming Zhang, Zhaohui Ni,  Renoprotective Mechanisms of Astragaloside IV in Cisplatin-Induced Acute Kidney Injury  Free Radic Research  2017  51 (7-8), 669-683 
    Wu H, Huang T, Ying L, Han C, Li D, Xu Y, Zhang M,, Dong Z  MiR-155 is Involved in Renal Ischemia-Reperfusion Injury via Direct Targeting of FoxO3a and Regulating Renal Tubular Cell Pyroptosis  Cell Physiol Biochem  2016  40 6 1692~1705 
    Yuan Y, Wang C, Shao X, Wang Q, Che X, Zhang M, Xie Y, Tian L, Ni Z,  Urinary retinol-binding protein as a risk factor of poor prognosis in acute-on-chronic renal injury  J Nephrol  2016  Jul 7 
    Xie Y, Wang Q,Wang C, Qi C, Ni Z,  igh urinary excretion of kidney injury molecule-1 predicts adverse outcomes in acute kidney injury: a case control study  Crit Care  2016  20 1 286 
    Tian L, Shao X, Xie Y, Wang L, Wang Q, Che X, Ni Z,  The long-term efficacy and safety of immunosuppressive therapy on the progression of IgA nephropathy: a meta-analysis of controlled clinical trials with more than 5-year follow-up.   Expert Opin Pharmacother.   2015  16(8):1137-47. 
    Yuan Y, Che X, Ni Z, Zhong Y, Qi Y, Shao X, Wang Q, Cao L, Zhang M, Xie Y, Qi C, Tian L,  Association of Relapse with Renal Outcomes under the Current Therapy Regimen for IgA Nephropathy: A Multi-Center Study  PLoS One  2015  10(9):e0137870 
    Xu Y, Xie Y, Shao X, Ni Z,  L-FABP: A novel biomarker of kidney disease.   Clin Chim Acta. .  2015  20;445:85-90 
    Che X, Wang Q, Xie Y, Xu W, Shao X,, Ni Z.  Astragaloside IV suppresses transforming growth factor-β1 induced fibrosis of cultured mouse renal fibroblasts via inhibition of the MAPK and NF-κB signaling pathways.   Biochem Biophys Res Commun.   2015  464(4):1260-6 
    Yuan Y, Wang Q, Ni Z, Che X, Cao L, Shao X, Zhang M, Xie Y, Qi C, Zhou W, Tian L,  Long-term kidney survival analyses in IgA nephropathy patients under steroids therapy: a case control study.   J Transl Med.   2015  13:186 
    Wang Q, Shao XH, Xu WJ, Qi CJ, Gu LY, Ni ZH,  Astragalosides IV inhibits high glucose-induced cell apoptosis through HGF activation in cultured human tubular epithelial cells  Ren Fail  2014  36(3):400-6 
    Xie Y, Xue W, Shao X, Che X, Xu W, Ni Z,  Analysis of a Urinary Biomarker Panel for Obstructive Nephrology and Clinical Outcomes  Plos One  2014  9(11):e112865 
    Xie YY, Xu WJ, Wang Q, Shao XH, Ni ZH,  Urinary excretion of liver-type FABP as a new clinical marker for the progression of obstructive nephropathy  Biomarkers Med  2014  8(4)：543–556 
    Che X, Xie Y, Wang C, Wang Q, Zhang M, Qi C, Ni Z,  Blood HCO3- concentration predicts the long-term prognosis of acute kidney injury patients  Biomarkers in Medicine  2014  8(10):1219-26 
    Xue W, Xie YY, Wang Q, Xu WJ,  Diagnostic performance of urinary kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin for acute kidney injury in an obstructive nephropathy patient  Nephrology  2014  19:186–194 
    Ni Z, Yuan Y, Wang Q, Cao L, Che X, Zhang M, Xie Y, Qi C,  Time-averaged albumin predicts the long-term prognosis of IgA nephropathy patients who achieved remission  Journal of Translational Medicine  2014  10;12(1):194 
    Xu W, Shao X, Tian L, Gu L, Zhang M, Wang Q, Wu B, Wang L, Yao J, Xu X,, Ni Z  Astragaloside IV Ameliorates Renal Fibrosis via the Inhibition of Mitogen-Activated Protein Kinases and Antiapoptosis In Vivo and In Vitro  Journal of Pharmacology and Experimental Therapeutics  2014  350(3):552-562 
    Shao XH, Tian L, Xu WJ, Zhang Z, Wang CL, Qi CJ,  Diagnostic Value of Urinary Kidney Injury Molecule 1 for Acute Kidney Injury: A Meta-Analysis  PLoS ONE  2014  9(1): e84131 
    Wang Q,, Xu W, Qi C, Ni Z.   Predicting mortality in microscopic polyangiitis with renal involvement: a survival analysis based on 64 patients.   Ren Fail.   2013  35(1):82-87.  
    , Li J, Yu Z, Wang Q, Ni Z.  Keto acid-supplemented low-protein diet for treatment of adult patients with hepatitis B virus infection and chronic glomerulonephritis.   J Int Med Res.  2013  41(1):129-137. 
    , Wang Q, Fang W, Lin A, Shi B, Cao L, Zhou W, Qian J, Ni Z  Change in cardiovascular disease status in peritoneal dialysis patients: a 5-year single-center experience  Ren Fail  2012  34(1):28-34 
    Qin Wang,, Weijia Xu, Chaojun Qi and Zhaohui Ni  Predicting Mortality in Microscopic Polyangiitis with Renal Involvement:A Survival Analysis Based on 64 Patients  Ren Fail  2012  35(1):82-7 
    , Wang Q, Li J, Shi B, Ni Z  Urinary excretion of liver-type fatty acid-binding protein as a marker of progressive kidney function deterioration in patients with chronic glomerulonephritis  Clin Chim Acta  2012  413(1-2):187-91 
    , Wang Q, Liu J, Che X, Zhang M, Cao L, Zhou W, Ni Z  Prevalence of non-diabetic renal disease in patients with type 2 diabetes  Diabetes Res Clin Pract  2010  87(3):354-9