• 基本信息
    导师姓名: 陈正侬 学科代码: 100213
    性别: 学科名称: 耳鼻咽喉科学
    培养单位: 附属第六人民医院 三级学科
    导师类型: 博士生导师 专业领域名称: 耳鼻咽喉科学 专业学位
    联系方式: 专业领域代码: 105117
    邮编: 200233 邮箱地址: jassey@126.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    中国医师协会显微外科分会常务委员
    中国医疗保健国际交流促进会耳鼻咽喉头颈外科分会青年委员会副主任委员
    上海市医学会耳鼻咽喉头颈外科专科分会青年委员会副主任委员
    中华耳科学杂志 编委
    中国医师协会显微外科分会耳神经及侧颅底显微修复委员会主任委员
    中华医学会耳鼻咽喉头颈外科分会青年委员会副主任委员
    World Skull Base Group Faculty
    中华医学会耳鼻咽喉头颈外科分会青年委员会副主任委员
    国际耳内科协会委员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    81770998Piccolino调控CaV1.3分布影响Ribbon突触的时间信息处理能力国家自然科学基金面上项目 2021-01~2024-12 56万元  课题负责人
    81770998VGLUT3改善低强度噪声所致的听觉功能障碍国家自然科学基金面上项目 2018-01~2021-12 70万元  课题负责人
    15PJD030FGF22防治噪声所致的Ribbon突触损伤上海市科委 2015-08~2017-07 20万元  课题负责人
    81371085Iduna通过拮抗Parthanatos防治噪声性聋国家自然科学基金 2014-01~2017-12 70万元  课题负责人
    30901669改良AAV2载体提高目的基因耳蜗毛细胞转染效率的研究国家自然科学基金 2010-01~2012-12 23万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Zong HQ,Lou ZH,Lou ZC,  Low-temperature plasma radiofrequency ablation tuboplasty and myringotomy: A preliminary report  American journal of pathology  2023  44(2):103766 
    Xu MX,Wang SM,Jiang YM,Wang JJ,Xiong YP,Dong WQ,Yao QX,Xing YZ,Liu F,  Single-Cell RNA-Seq Reveals Heterogeneity of Cell Communications between Schwann Cells and Fibroblasts within Vestibular Schwannoma Microenvironment  American journal of pathology  2022  192(9):1230-1249 
    Lou Z,Lou Z,Jin K,Sun J,  Excising or preserving perforation margins in endoscopic transtympanic cartilage myringoplasty does not affect surgical success  Clin Otolaryngol  2022  47(1):94-99 
    Liu YQ,Wu CP,Chen TT,Shen QY,Xiong YP,,Li CY  Evaluation of acoustic changes in and the healing outcomes of rat eardrums with pars tensa and pars flaccida perforations  Laryngoscope investigative otolaryngology  2022  7(3):816-824 
    Lou Z,Lou Z,Yu D,Wang J,Lv T,  Comparison of endoscopic over-underlay technique with and without packing for repairing chronic perforation  Eur Arch Otorhinolaryngol  2022  9(17):7-14 
    Jiang YM,Xu MX,Yao QX,Li ZZ,Wu YQ,,Yu DZ,Shi HB,Yin SK  Changes of Vestibular Symptoms in Menière's Disease After Triple Semicircular Canal Occlusion: A Long-Term Follow-Up Study  Frontiers in Neurology  2022  13:797699 
    Lou Z,Lou Z,Jiang Y,  FGF2 and EGF for the Regeneration of Tympanic Membrane: A Systematic Review  Stem Cells Int  2021  29;2021:2366291 
    Lou Z,Lou Z,Jin K,Sun J,  Comparison of long-term outcome of two endoscopic transtympanic myringoplasty without tympanomeatal flap elevating for repairing large chronic perforations.  Eur Arch Otorhinolaryngol  2021  279(5):2293-2301. 
    Liu M,Lou Z,Jin K,Sun J,  The feasibility of intranasal endoscopic microwave ablation on the removal of nasolabial cyst: Preliminary case series  Am J Otolaryngol  2021  42(3):103018 
    Lou Z,Lou Z,Sun J,,Yin S  Microwave ablation eustachian tuboplasty: a preliminary investigation with long-term follow-up  J Otolaryngol Head Neck Surg  2021  50(1):39 
    Tang Y,Lou Z,Lou Z,Jin K,Sun J,  Is no de-squamatization of the TM reliable for cartilage over-underlay myringoplasty without external auditory canal packing?  Am J Otolaryngol.  2021  42(5):103064 
    Li C,Zhou H,Feng Y,Zhao Y,Wang J,,Yin S  Coagulation States in Patients With Sudden Sensorineural Hearing Loss Evaluated by Thromboelastography  Otolaryngol Head Neck Surg  2021  164(6):1280-1286. 
    Lou Z,Lou Z,Jin K,Sun J,  Topical Application of bFGF Alone for the Regeneration of Chronic Tympanic Membrane Perforations: A Preliminary Case Series  Stem Cells Int  2021  15;2021:5583046 
    Zheng Z, Shen Y, Xia L, Wu H, Zhou H, Tang X, Meng L, Wang H, Wu Y, Shi H, Yin S, Feng Y,  Glucocorticoid and Breviscapine Combination Therapy Versus Glucocorticoid Alone on Sudden Sensorineural Hearing Loss in Patients with Different Audiometric Curves  Adv Ther  2020  37(12):4959-4968 
    Zhang Z, Fan L, Xing Y, Wang J, Aiken S,, Wang J*  Temporary Versus Permanent Synaptic Loss from Repeated Noise Exposure in Guinea Pigs and C57 Mice.  Neuroscience  2020  28;432:94-103 
    He S, Hu J, Zheng Z, Wang J, Chen J, Zhang C, Li L, Wang J,, Shi H, Wang J  Establishment of an induced pluripotent stem cell line from a patient with CHARGE syndrome carrying a CHD7 (p.L1151Gfs*17) mutation.  Stem Cell Res  2020  May;45:101774 
    Zhuang Q, Wei N, Zhou Q, Wang H, Wu Y,, Yu D, Wang P*, Shi H.   Efficacy and Timing of Neonatal Ear Correction Molding.  Aesthetic Plast Surg  2020  21 
    Fan L, Zhang Z, Wang H, Li C, Xing Y, Yin S,, Wang J.  Pre-exposure to Lower-Level Noise Mitigates Cochlear Synaptic Loss Induced by High-Level Noise  Front Syst Neurosci.  2020  12;14:25. 
    Li C, Zhou H, Feng Y, Zhao Y, Wang J,, Yin S.  Coagulation States in Patients With Sudden Sensorineural Hearing Loss Evaluated by Thromboelastography  Otolaryngol Head Neck Surg  2020  3:194599820965240 
    Zhang Z,,Fan L,Landry T,Brown J,Yu Z,Yin S,Wang J.  Ultrasound-microbubble cavitation facilitates adeno-associated virus mediated cochlear gene transfection across the round-window membrane  Bioeng Transl Med  2020  6(1):e10189 
    Wang J, Feng Y, Wang H, Li C, Wu Y, Shi H,, Chen Z.  Prevalence of High Jugular Bulb across Different Stages of Adulthood in A Chinese Population  Aging Dis  2020  23;11(4):770-776 
    Huang S, Wang D, Zhou H,, Wang H*, Li Y, Yin S*  Neuroimaging consequences of cerebral small vessel disease in patients with obstructive sleep apnea-hypopnea syndrome.  Brain Behav  2019  9(8):e01364 
    Wang JJ, Feng YM, Wang H, Wu YQ, Shi HB,, Yin SK*  Changes in tinnitus after vestibular schwannoma surgery.  Sci Rep  2019  11;9(1):1743 
    Wang JJ, Feng YM, Wang H, Wu YQ, Shi HB,, Yin SK  Postoperative efficacy analysis of patients with facial nerve palsy associated with cholesteatoma otitis media: Our experience with 32 patients.  Clin Otolaryngol.  2018  43(2):732-735 
    Sun Y, Guo Y, Wang H,, Wu Y, Shi H, Feng Y*, Yin S  Differences in platelet-related parameters among patients with audiographically distinct sudden sensorineural hearing loss: A retrospective study.  Medicine (Baltimore)  2017  96(36):e7877 
    Zeng S, Sun X,, Yu D, Chen B, Yin S  Low, but Not High, Doses of Cisplatin Damage Cochlear Hair Cells in C57 Mouse Organotypic Cultures.  ORL J Otorhinolaryngol Relat Spec  2016  78(4):177-186. 
    王菁菁, 冯艳梅, 吴雅琴, 王慧, 时海波,, 殷善开  影响面神经减压术疗效的因素  上海交通大学学报(医学版)  2016  36(09): 1329-1331 
    , Prasad SC, Di Lella F, Medina M, Piccirillo E, Taibah A, Russo A, Yin S, Sanna M  The behavior of residual tumors and facial nerve outcomes after incomplete excision of vestibular schwannomas  J Neurosurg  2014  120(6):1278-87 
    Ruan Q, Ao H, He J,, Yu Z, Zhang R, Wang J, Yin S  Topographic and quantitative evaluation of gentamicin-induced damage to peripheral innervation of mouse cochleae  Neurotoxicology  2014  40:86-96 
    Ruan Q, Zeng S, Liu A,, Yu Z, Zhang R, He J, Bance M, Robertson G, Yin S, Wang J  Overexpression of X-Linked Inhibitor of Apoptotic Protein (XIAP) reduces age-related neuronal degeneration in the mouse cochlea  Gene Ther  2014  21(11):967-74 
    Zhou H, Sun X,, Shi H, Zhang W, Yin S.  Evaluation of cochlear implantation in children with inner ear malformation  B-ENT  2014  10: 265-269 
    , Zhou H, Shi H, Wu Y, Yin S  Comparison of hearing results of MVP and TORP for chronic otitis media patients with a mobile stapes footplate  Ann Otol Rhinol Laryngol  2014  123(5):343-6 
    Xia L,, Su K, Yin S  Comparison of cochlear cell death caused by cisplatin, alone and in combination with furosemide  Toxicol Pathol  2014  42(2):376-85 
    Zhou H,, Shi H, Wu Y, Yin S  Categories of Auditory Performance and Speech Intelligibility Ratings of Early-Implanted Children without Speech Training  PLoS One  2013  8(1):e53852 
    Xia L,, Yin S  Ototoxicity of cisplatin administered to guinea pigs via the round window membrane  J Toxicol Sci  2012  37(4):823-30 
    , Yin SK.  Cochlear implantation in a patient with bilateral temporal bone fractures resulting from temporomandibular joint surgery  Chin Med J (Engl)  2012  125(22):4160 
    Ye HB, Shi HB, Wang J, Ding DL, Yu DZ,, Li CY, Zhang WT, Yin SK  Bilirubin induces auditory neuropathy in neonatal guinea pigs via auditory nerve fiber damage  J Neurosci Res  2012  90(11):2201-13 
    Zhou H,, Shi H, Wu Y, Yin S  Comparisons of auditory performance and speech intelligibility in children with cochlear implants placed using different approaches  Otol Neurotol  2012  33(1):26-9 
    Li CY, Shi HB,, Ye HB, Song NY, Yin SK  Protein kinase A and C signaling induces bilirubin potentiation of GABA/glycinergic synaptic transmission in rat ventral cochlear nucleus neurons  Brain Res  2010  12:1348:30-41 
    Chen B, Yu D,, Yin S.  Fos expression in the rat vestibular nucleus complex after plugging the three semicircular canals  Audiol Neurootol  2009  14(4):209-213 
    , Jian Wang, Yin S.  Off-channel effect of High Frequency Overstimulation on Duration Tuning of low-frequency Inferior Colliculus neurons of Guinea Pigs  Acta Otolaryngol  2009  129(12):1451-5 
    Yu D,, Yin S  Effect of baclofen on neuronal activity in the medial vestibular nucleus after unilateral surgical labyrinthectomy in rats  Acta Oto-Laryngologica  2009  129:735-740 
    , Yu D, Wu Y, Shi H, Zhou H, Yin S  The indications and common surgical approaches for cochlear implantation in China  ORL J Otorhinolaryngol Relat Spec  2009  71(4):187-91 
    , Yu D, Wu Y, Shi H, Zhou H, Wang J, Yin S  Surgical treatment of labyrinthine fistula caused by cholesteatoma with semicircular canal occlusion  Acta Otolaryngol  2009  1:1-4 
    Yin S,, Wang L, Wu Y,.   Suprameatal approach for cochlear implantation in 45 Chinese Children  Int J Pediatr Otorhinolaryngol  2008  72(3):397-403 
    , Yu D, Wu Y, Yin S, Wang J.  Horizontal Semicircular Canal Occlusion in a Patient with Benign Paroxysmal Positional Vertigo  J Otolaryngol Head Neck Surg  2008  37(3):E69-72 
    Yin S,, Feng Y, Wang J  Local Inhibition Shapes Duration Tuning in The Inferior Colliculus of Guinea Pigs  Hear Res  2008  237(1-2):32-48 
    Yin S, Feng Y,,Wang J  The effect of noise-induced sloping high-frequency hearing loss on the gap response in the inferior colliculus and auditory cortex of guinea pigs  Hear Res  2008  239(1-2):126-40 
    Yin S,,Yu D, Wu Y, Shi H, Zhou H  Triple Semicircular Canal Occlusion for the Treatment of Ménière’s Disease  Acta Oto-Laryngologica  2008  128(7):739-43 
    Yin S,, Feng Y, Wang J.  The roles of local inhibition mediated by aminobutyric acid (GABA)-A receptor in duration tuning in the inferior colliculus of guinea pigs  Acta Otolaryngol  2008  128(10):1101-9. 
    Yin S, Yu D,, Cao Z, Wang J  Important factors for the hearing loss caused by the triple semicircular canal occlusion in guinea pigs.  Otol Neurotol.   2007  28(4):513-9. 
    Wang J, van Wijhe R,, Yin S  Is duration tuning a transient behavior in the inferior colliculus of guinea pigs?   Brain Res  2006  1114(1):63-74 
    Wang LE, Cao KL, Yin SK, Wang Z,  Cochlear function after selective spiral ganglion cells degeneration induced by ouabain.  Chin Med J (Engl)  2006  119(12):974-9