- 基本信息
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导师姓名：
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李彦欣
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学科代码：
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100214
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性别：
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女
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学科名称：
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肿瘤学
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培养单位：
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附属儿童医学中心
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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联系方式：
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02138087418
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专业领域代码：
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邮编：
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200127
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邮箱地址：
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liyanxin@scmc.com.cn
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- 研究方向 (点击浏览详细信息)
- 社会任职
- 科研项目
| 23ZR1441000 | 胚系RAS突变抑制幼年型粒单核细胞白血病（JMML）恶性增殖的分子机制 | 上海市自然科学基金面上项目 |
2023-04~2026-03
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20万元
| 课题负责人 |
| 32271007 | KAP1调控启动子近端暂停-释放在儿童高危神经母细胞瘤发展中的作用及分子机制 | 国家自然科学基金面上项目 |
2023-01~2026-12
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54万元
| 课题负责人 |
| 81972341 | TRIM24在MYCN调控的高危儿童神经母细胞瘤增殖中的作用及机制 | 国家自然基金面上项目 |
2020-10~2023-12
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55万元
| 课题负责人 |
| 2018YFC1313005 | 高危神经母细胞瘤发生、复发及转移的分子基础研究 | 重大慢性非传染性疾病防控研究 |
2018-01~2020-12
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1200万元
| 课题参与人 |
| 81772663 | 泛素连接酶TRIM59调控胶质瘤发生发展的分子机制 | 国家自然基金面上项目 |
2018-01~2022-12
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55万元
| 课题负责人 |
| YG2017MS32 | 泛素连接酶在肿瘤及肿瘤干细胞中的作用 | “医工交叉研究基金” |
2018-01~2020-12
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21万元
| 课题负责人 |
- 学术论文
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Qiqi Shi, Bo Yu, Yingwen Zhang, Yi Yang, Chenxin Xu, Mingda Zhang, Guoyu Chen, Fei Luo, Bowen Sun, Ru Yang,, Haizhong Feng*
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Targeting TRIM24 promotes neuroblastoma differentiation and decreases tumorigenicity via LSD1/CoREST complex
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Cell Oncol (Dordr)
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2023
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doi: 10.1007/s13402-023-00843-4
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Wanqiao Wang#, Xin Li#, Xia Qin#, Yan Miao#, Yingwen Zhang, Shanshan Li, Ruen Yao, Yi Yang, Lisha yv, Hua Zhu, Lili Song, Shengqiao Mao, Xiumin Wang*, Jing Chen*, Haizhong Feng*,
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Germline Neurofibromin 1 mutation enhances the antitumor immune response and decreases juvenile myelomonocytic leukemia tumorigenicity
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British Journal of Haematology
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2023
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202(2):328-343
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Hui Xiao#, Siqi Wang, Yuejia Tang, Shanshan Li, Yufeng Jiang, Yi Yang, Yinwen Zhang, Yali Han, Xiaoyu Wu, Liang Zheng,, Yijin Gao*
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Absence of terminal deoxynucleotidyl transferase expression in T-ALL/LBL accumulates chromosomal abnormalities to induce drug resistance
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Int J Cancer
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2023
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152(11):2383-2395
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Yi Yang#, Siqi Wang#, Jiaoyang Cai#, Jianwei Liang#, Yingwen Zhang, Yangyang Xie, Fei Luo, Jingyan Tang, Yijin Gao*, Shuhong Shen*, Haizhong Feng*,
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Targeting ARHGEF12 promotes neuroblastoma diferentiation, MYCN degradation, and reduces tumorigenicity
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Cell Oncol (Dordr)
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2023
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46(1):133-143
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Li S#, Song L, Zhang Y, Zhan Z, Yang Y, Yu L, Zhu H, Huang W, Wang W, Feng H*,
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Optimizing the Method for Differentiation of Macrophages from Human Induced Pluripotent Stem Cells
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Stem Cells Int
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2022
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2022: 6593403
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Yi Yang#, Lili Song#, Xia Huang#, Yanan Feng#, Yingwen Zhang, Yanfeng Liu, Shanshan Li, Zhiyan Zhan, Liang Zheng*, Haizhong Feng*,
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PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness
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Aging-US
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2021
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13(3), 4063-4078
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Bo Yu#, Fei Luo, Bowen Sun, Wenxue Liu, Qiqi Shi, Shi-Yuan Cheng, Ceshi Chen, Guoqiang Chen,, Haizhong Feng*
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KAT6A acetylation of SMAD3 regulates myeloid-derived suppressor cell recruitment, metastasis, and immunotherapy in triple-negative breast cancer
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Advanced Science
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2021
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2021 Oct;8(20):e2100014
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Jin Wook Kang#, Zhiyan Zhan#, Guangzhen Ji#, Youzhou Sang, Daohong Zhou,, Haizhong Feng*, and Tao Cheng*
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PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells
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Signal Transduction and Targeted Therapy
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2021
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6(1):129
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Lili Song#, Bo Yu#, Yi Yang, Jianwei Liang, Yingwen Zhang, Lixia Ding, Tianyi Wang, Xinyu Wan, Xiaomin Yang, Jingyan Tang, Shengyue Wang*, Benshang Li*,, Haizhong Feng*
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Identification of functional cooperative mutations of GNAO1 in human acute lymphoblastic leukemia
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Blood
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2021
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137(9):1181-1191
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Yang Li#, Ting Li#, Yuejia Tang#, Zhiyan Zhan, Lixia Ding, Lili Song, Tingting Yu, Yi Yang, Jing Ma, Yingwen Zhang, Ying Zhou, Song Gu, Min Xu*, Yijin Gao*,
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The function of a heterozygous p53 mutation in a Li-Fraumeni syndrome patient
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Plos One
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2020
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9;15(6):e0234262
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Ting Li*, Lili Song*, Yingwen Zhang*, Yali Han*, Zhiyan Zhan, Zhou Xv, Yang Li, Yuejia Tang, Yi Yang, Siqi Wang, Shanshan Li, Liang Zheng#,, Yijin Gao#
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Molecular mechanism of c-Myc and PRPS1/2 against thiopurine resistance in Burkitt's lymphoma
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Journal of cellular and molecular medicine
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2020
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24(12):6704-6715
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Yinfang Wang, Yanli Hou, Weiwei Zhang, Angel A. Alvarez, Yongrui Bai, Bo Hu, Shi-Yuan Cheng, Kun Yang*,, and Haizhong Feng*
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Lipolytic inhibitor G0S2 modulates glioma stem-like cell radiation response
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Journal of Experimental & Clinical Cancer Research
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2019
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38:147
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Youzhou Sang# , Yanli Hou# , Rongrong Cheng, Liang Zheng, Angel A. Alvarez, Bo Hu, Shi-Yuan Cheng, Weiwei Zhang* ,, and Haizhong Feng*
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Targeting PDGFR -activated Glioblastoma through Specific Inhibition of SHP-2-mediated Signaling
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Neuro Oncol
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2019
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21(11):1423-1435
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Zhiyan Zhan#, Lili Song#, Weiwei Zhang#, Haihui Gu, Haizi Cheng, Yingwen Zhang, Yi Yang, Guangzhen Ji , Haizhong Feng*, Tao Cheng*,
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Absence of cyclin-dependent kinase inhibitor p27 or p18 increases efficiency of iPSC generation without induction of iPSC genomic instability
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Cell Death & Desease
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2019
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10(4):271
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Cai Jiaoyang#, Huang Xia#, Yin Minzhi#, Pa Ci, Song Lili, Zhan Zhiyan, Chen Jing, Gao Yijin, Tang Jingyan,, Shen Shuhong*
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A novel fusion gene PLEKHA6-NTRK3 in langerhans cell histiocytosis
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International Journal of Cancer
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2019
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144(1):117-124
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