• 基本信息
    导师姓名： 路丽明 学科代码： 100100
    性别： 女 学科名称： 基础医学
    培养单位： 基础医学院 三级学科
    导师类型： 博士生导师 专业领域名称：
    联系方式： 重庆南路280号5号楼1208 lulunew2003@163.com 专业领域代码：
    邮编： 200025 邮箱地址： lulunew2003@163.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    上海市免疫学会第十三届理事会 副秘书长
    中国病理生理学会实验血液学专业委员会常务委员
    中国遗传学会遗传诊断分会 委员
    上海市免疫学会免疫遗传分会 副主任委员
    上海市免疫学会第十三届理事会移植免疫专业委员会 常务委员
    上海市期刊协会理事
    中国细胞治疗质量控制与研究专业委员会 常务委员
    中国免疫学会健康委员会 常务委员
    亚太免疫生物治疗学会理事 常务委员
    中华医学会儿科学会疫苗接种委员会常务委员
    上海市免疫学会常务理事
    中华医学生物免疫学会常务理事
    中国免疫学会科学普及教育工作委员会 委员
    上海市免疫学会肿瘤分会 委员
    中华生物免疫治疗学会 理事,常务委员
    《现代免疫学》杂志 执行主编
    上海市医学会妊娠免疫专科分会副主任委员
    国自然面上项目评审专家
    教育部学位中心全国优秀博士论文 评审专家
    Clinic immunology，Stem cells，Journal of immunology等审稿人
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    2060302栝篓来源的中药天花粉蛋白及其生菜表达重组蛋白治疗炎症性肠病的应用探索名贵中药资源可持续利用能力建设项目 2024-10~2026-12 50万元  课题负责人
    22490760400中药天花粉蛋白作为干细胞来源新型冠状病毒疫苗高效能增强剂的可行性研究上海市科学技术委员会 2022-09~2025-08 30万元  课题负责人
    82071856中药天花粉蛋白作为A群流脑疫苗免疫增效剂的应用基础研究国家自然科学基金项目 2021-01~2024-12 52万元  课题负责人
    2020YFA0113101人脐带间充质干细胞治疗视神经脊髓炎谱系疾病的临床研究重点研发计划项目 2021-01~2025-12 83万元  课题参与人
    2020JP009组蛋白去甲基化酶LSD1对天花粉蛋白诱导的CD8+Treg谱系维持的作用上海市卫生健康委员会 2020-08~2022-08 4万元  课题负责人
    18140903800建立KRAS突变肺癌双人源化小鼠模型并用于临床患者药物治疗方案评估的探索上海市科学技术委员会 2018-05~2021-04 60万元  课题负责人
    2017YFA0104600单倍型相合移植（“北京方案”）后适应性免疫重建及调控机制国家重点研发计划重点专项项目 2017-07~2021-12 889万元  课题负责人
    16SG14中药天花粉蛋白衍生肽通过Treg细胞延缓肺移植术后闭塞性细支气管炎综合症的可行性研究上海市教委 2017-01~2019-12 15万元  课题负责人
    81671579Treg抑制同种异体肺移植慢性排斥的应用基础研究国家自然科学基金，面上项目 2017-01~2020-12 57万元  课题负责人
    15PJD021中药天花粉蛋白来源的生物活性多肽治疗Th1细胞主宰疾病的药效及作用机理研究上海市浦江人才计划（D类） 2015-09~2017-08 20万元  课题负责人
    15401900500Tk-PQ作为高效低毒免疫调节剂的成药性研究上海市科委中药新药候选药物研究 2015-07~2018-09 50万元  课题负责人
    14DZ1931003TIL细胞治疗肺癌的医学转化研究上海市科委产学研项目 2014-08~2017-09 10万元  课题负责人
    31370904CIITA通过NLR信号调控Th2应答的分子免疫学机制国家自然科学基金，面上项目 2014-01~2017-12 80万元  课题负责人
    C080102IL-9(+)IL-10(+)T细胞与Th9的免疫生物学特性比较研究国家自然基金，面上项目 2010-01~2012-12 28万元  课题负责人
    30700766CIITA突变体功能性剔除MHC及作用机制的研究国家自然基金委,面上项目 2008-01~2010-12 17万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Zhang D, Heng Y, Jin QY, Tang D, Zhu XK,, Wu CP, Tao L  Prognostic significance of cytotoxic-T-lymphocytes to immunosuppressive lymphocytes ratio (CIL) in laryngeal squamous cell carcinoma  Cancer Immunol Immunother  2025  74(5):157 
    Zhou D, Xu W, Ding X, Guo H, Wang J, Zhao G, Zhang C, Zhang Z, Wang Z, Wang P,, Yuan M  Transient inhibition of neutrophil functions enhances the antitumor effect of intravenously delivered oncolytic vaccinia virus  Cancer Sci  2024  115(4):1129-1140 
    Yangyang Ji , Yu Heng, Xiaoke Zhu , Duo Zhang, Di Tang, Jian Zhou , Hanqing Lin , Jingyu Ma , Xuping Ding , Lei Tao ,  Increased tumor-infiltrating plasmacytoid dendritic cells express high levels of PD-L2 and affect CD8+ lymphocyte infiltration in human laryngeal squamous cell carcinoma  Translational Oncology  2024  45:101936. 
    Zhu X, Heng Y, Zhang D, Tang D, Zhou J, Lin H, Ma J, Ding X, Tao L,  Prognostic significance and immune escape implication of tumor-infiltrating neutrophil plasticity in human head and neck squamous cell carcinoma  Hum Cell  2024  37(3):714-728 
    Ma J, Zhu X, Heng Y, Ding X, Tao L,  Establishment and characterization of a novel hypopharyngeal squamous cell carcinoma cell line CZH1 with genetic abnormalities  Hum Cell  2024  37(2):546-559 
    Yunbin Zhang, Xuping Ding, Qian Zhang, Cong Zeng, Hongzhuan Chen,  Trichosanthin elicits antitumor activity via MICU3 mediated mitochondria calcium influx  J Adv Res  2024  S2090-1232(24)00493-4 
    Xiaoke Zhu, Yu Heng , Jingyu Ma, Duo Zhang , Di Tang , Yangyang Ji , Changding He , Hanqing Lin, Xuping Ding, Jian Zhou , Lei Tao ,  Prolonged Survival of Neutrophils Induced by Tumor-Derived G-CSF/GM-CSF Promotes Immunosuppression and Progression in Laryngeal Squamous Cell Carcinoma  Adv Sci (Weinh)  2024  24:e2400836  
    Heng Y,Zhu XK,Lin HQ,Ma JY,Ding XP,Zhang D,Tang D,Tao L,  CD206+ tumor-associated macrophages interact with CD4+ tumor-infiltrating lymphocytes and predict adverse patient outcome in human laryngeal squamous cell carcinoma  Journal of Translational Medicine  2023  21(1):167 
    Heng Y, Zhu X, Wu Q, Lin H, Ding X, Tao L,  High Expression of Tumor HLA-DR Predicts Better Prognosis and Response to Anti-PD-1 Therapy in Laryngeal Squamous Cell Carcinoma  Transl Oncol  2023  33:101678 
    Lv QM, Lei HM, Wang SY, Zhang KR, Tang YB, Shen Y,, Chen HZ, Zhu L  Cancer cell-autonomous cGAS-STING response confers drug resistance  Cell Chem Biol  2023  30(6):591-605 
    Jie Shu, Kefan Wang, Yuting Liu, Jie Zhang, Xuping Ding, Hanxiao Sun, Jiaoxiang Wu, Biao Huang, Ju Qiu, Huiming Sheng,  Trichosanthin alleviates streptozotocin-induced type 1 diabetes mellitus in mice by regulating the balance between bone marrow-derived IL6+ and IL10+ MDSCs  Heliyo  2023  10(1):e22907 
    Yuting Liu,Kefan Wang,Shuofei Yang,Guanhua Xue,  Mulberry extract upregulates cholesterol efflux and inhibits p38 MAPK-NLRP Mediated inflammation in foam cells  Food Science&Nutrition  2023  11(6):3141-3153 
    Zhang D,Tang D,Liu PT,Tao L,  Isolation of tumor stem-like cells from primary laryngeal squamous cell carcinoma cells (FD-LS-6)  Hum Cell  2023  2023 Sep 27 
    Zhou L, Hou Y, Pan X, Wang X, Jin H, Yang X, Wang K, Ding X, Wang K, Zhu M, Pan Y, Wang W,  Trichosanthin-derived peptide Tk-PQ attenuates immune rejection in mouse tracheal allotransplant model by suppressing PI3K-Akt and inducing type II immune polarization   Int Immunopharmacol  2023  125(Pt A):111081 
    Di Tang, Duo Zhang, Yu Heng, Xiao-ke Zhu, Han-qing Lin, Jian Zhou, Lei Tao,  Tumor-infiltrating PD-L1+ Neutrophils Induced by GM-CSF Suppress T Cell Function in Laryngeal Squamous Cell Carcinoma and Predict Unfavorable Prognosis  Journal of Inflammation Research  2022  16;15:1079-109 
    Wang T,Zhang D,Tang D,Heng Y,,Tao L  The role of systemic inflammatory response index (SIRI) and tumor-infiltrating lymphocytes (TILs) in the prognosis of patients with laryngeal squamous cell carcinoma  J Cancer Res Clin Oncol  2022  149(9):5627-5636 
    Han Y,Ouyang X,Chen Y,Lai S,Sun H,Wu N,Ruan C,,Su B  scRNA-seq profiling of neonatal and adult thymus-derived CD4+ T cells by a T cell origin-time tracing model.  J Mol Cell Biol  2022  14(12):mjac072 
    Ruan D,Ye ZW,Yuan S,Li Z,Zhang W,Ong CP,Tang K,Ka Ki Tam TT,Guo J,Xuan Y,Huang Y,Zhang Q,Lee CL,,Chiu PCN,Yeung WSB,Liu F,Jin DY,Liu P  Human early syncytiotrophoblasts are highly susceptible to SARS-CoV-2 infection  Cell Rep Med  2022  3(12):100849 
    Di Tang,Duo Zhang,Yu Heng,Xiao-ke Zhu,Han-qing Lin,Jian Zhou,Lei Tao,  Tumor-infiltrating PD-L1+ Neutrophils Induced by GM-CSF Suppress T Cell Function in Laryngeal Squamous Cell Carcinoma and Predict Unfavorable Prognosis.  Journal of Inflammation Research  2022  15:1079-1097  
    Rui Guo,Shun-Yuan Lu,Jin-Xia Ma,Qian-Lan Wang,Lu Zhang,Ling-Yun Tang,Yan Shen,Chun-Ling Shen,Jin-Jin Wang,,Zhu-GangWang,Hong-Xin Zhang  RIG-I acts as a tumor suppressor in melanoma via regulating the activation of the MKK/p38MAPK signaling pathway  Hum Cell  2022  35(4):1071-1083. 
    ZongAn Chen, Zhen Gao, LingLing Xia, XiaoQing Wang,, XiaoLi Wu  Dysregulation of DPP4-CXCL12 balance by TGF-β1/SMAD pathway promotes CXCR4+ inflammatory cell infiltration in keloid scars  Journal of Inflammation Research  2021  14:4169-4180. 
    Duo Zhang, Di Tan, Yu Heng, Xiao-Ke Zhu, Liang Zhou, Lei Tao,  Prognostic Impact of Tumor-Infiltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma Patients  Laryngoscop  2021  131(4):E1249-E1255. 
    Kai Wang, Man Zhang, Jiao Wang, Jizhuang Luo, Pan Sun, Haizhen Jing, Rong Li, Changqing Pan,  A systematic analysis identifies key regulators involved in cell proliferation and potential drugs for the treatment of human lung adenocarcinoma  Frontiers in Oncology-Thoracic Oncology  2021  11:4-15 
    Zhang Yu,Zhou Lin,Gu Xiang,Feng Xuan,Ding Ping,Xia Qiang,  CXCL8high inflammatory B cells in the peripheral blood of patients with biliary atresia are involved in disease progression  Immunology & Cell Biology  2020  98(8):682-692 
    Zhang Na, Sun Pan, Jin Haizhen, Yang Yuqin, Zhao Qingya, Zhou Lin, Guo Lili, Yang Xiaohua,  Chidamide combined with paclitaxel effectively reverses the expression of histone deacetylase in lung cancer  Anti-Cancer Drugs  2020  31(7):702-708 
    Yi Xue , Di Tang , Sheng-Jie Li , Jian Zhou , Chi-Yao Hsueh , Dan-Dan Zhao , Yu Heng , Lei Tao,  Link Between CIITA rs3087456 Polymorphism and the  Pathol Res Pract  2020  216(1):152793 
    Jian Zhou, Liang Zhou, Duo Zhang, Wei-Jing Tang, Di Tang, Xiao-Ling Shi, Yue Yang, Lin Zhou, Fei Liu, Yong Yu, Pentao Liu, Lei Tao,  BCL11A promotes the progression of laryngeal squamous cell carcinoma  Frontiers in  2020  10:375 
    He Yu-Bin,Guo Jiang-Hong,Wang Chong,Zhu Dan,  IL-33 promotes the progression of nonrheumatic aortic valve stenosis via inducing differential phenotypic transition in valvular interstitial cells.  Journal of cardiology.  2020  75(2):124-133 
    Christopher D Nishimura, Marc C Pulanco, Wei Cui,, Xingxing Zang  PD-L1 and B7-1 Cis-Interaction: New Mechanisms in Immune Checkpoints and Immunotherapies  Trends Mol Med  2020  27(3):207-219 
    Jun Lu, Hua Zhong, Tianqing Chu, Xueyan Zhang, Rong Li, Jiayuan Sun, Runbo Zhong, Yuqin Yang, Mohammad Shah Alam, Yuqing Lou, Jianlin Xu, Yanwei Zhang, Jun Wu, Xiaowei Li, Xiaodong Zhao, Kai Li,, Baohui Han  Role of anlotinib-induced CCL2 decrease in anti-angiogenesis and response prediction for non-small cell lung cancer therapy  European Respiratory Journal  2019  53(3) 
    Yi xue, Huai-Dong Du, Di Tang, Duo Zhang, Jian Zhou, Chang-Wen Zhai, Cun-Cun Yuan, Chi-Yao Hsueh, Sheng-Jie Li, Yu Heng, Lei Tao,  Correlation Between the NLRP3 Inflammasome and the Prognosis of Patients With LSCC  FRONTIERS IN ONCOLOGY  2019  2:9:588. 
    Gao Xuefei, Nowak-Imialek Monika, Chen Xi, Chen Dongsheng, Herrmann Doris, Ruan Degong, Chen Andy Chun Hang, Eckersley-Maslin Melanie A, Ahmad Shakil, Lee Yin Lau,Kobayashi Toshihiro, Ryan David, Zhong Jixing, Zhu Jiacheng, Wu Jian, Lan Guocheng, Petkov Stoyan, Yang Jian, Antunes Liliana, Campos Lia S, Fu Beiyuan, Wang Shengpeng, Yong Yu, Wang Xiaomin, Xue Song-Guo, Ge Liangpeng, Liu Zuohua, Huang Yong, Nie Tao, Li Peng, Wu Donghai, Pei Duanqing, Zhang Yi,, Yang Fengtang. Kimber Susan J, Reik Wolf, Zou Xiangang, Shang Zhouchun, Lai Liangxue, Surani Azim, Tam Patrick P L, Ahmed Asif, Yeung William Shu Biu, Teichmann Sarah A, Niemann Heiner, Liu Pentao,  Establishment of porcine and human expanded potential stem cells  Nature cell biology  2019  21(6): 687 
    Guo-wei Tu ,Min-jie Ju, Guang-wei Hao,Guo-guang Ma, Jun-yi Hou, Xue-peng Zhang,Zhe Luo,  CXCL16/CXCR6 Is Involved in LPS-induced Acute Lung Injury via P38 Signaling  Cell Physiol Biochem  2019  23(8):5380-5389 
    陈广洁, 谢长宜, 钮晓音, 蒋黎华, 聂红,, 席晔斌, 葛海良  机体防御与免疫整合课程的实践与研究  中国高等医学教育  2018  (4): 16-17 
    Yue Wang, Qing Li, Lin Zhou, Xueping Ding,  Peptede TK-PQ induces immunosuppression in skin allogeneic transplantation via increasing Foxp3+ Treg and impeding nuclear translocation of NF-κB   Molecular Immunology  2018  101:597-607. 
    Xiaoyan Yu, Yimin Lao, Xiao-Lu Teng, Song Li, Yan Zhou, Feixiang Wang, Xinwei Guo, Siyu Deng, Yuzhou Chang, Xuefeng Wu, Zhiduo Liu, Lei Chen,, Jinke Cheng, Bin Li, Bing Su, Jin Jiang, Hua-Bing Li, Chuanxin Huang, Jing Yi & Qiang Zou  SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation  Nature communications  2018  9(1): 3157 
    李健,郭震,,李欣  无血预充大鼠体外循环模型的建立  中国体外循环杂志  2018  Vol．16 No． 3  
    衡宇, 查亚芳, 顾燕妮, 沈朝斌,  2018 年美国儿童预防接种最新指南解读及其与我国现状比较  现代免疫学  2018  38(04): 350-353 
    Xiao-yang Zhang, Lin Zhou, Zhen Guo, Ye Kong, Wei Zhang,,Xin Li*  Regulatory T Cells may Play an Protection Role in Lung Injury after Operation in Rheumatic Heart Disease  Journal of Thoracic Disease  2018  10(6) 
    Weimin Fan, Yali Xu, Yue Liu, Zhengqing Zhang,,Zhide Ding   Obesity or Overweight, a Chronic Inflammatory Status in Male Reproductive System, Leads to Mice and Human Subfertility   Frontiers in Physiology   2018  8:1117 
    Xiaoyan Yu, XiaoLu Teng, Feixiang Wang, Yuhan Zheng, Guojun Qu, Yan?Zhou, Zhilin Hu, Zhongqiu Wu, Yuzhou Chang, Lei Chen,HuaBing Li, Bing Su,, Zhiduo Liu, ShaoCong Sun, and Qiang Zou  Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome  J Exp Med  2018  3;215(9):2463-2476 
    李健,郭震,,李欣  无血预充大鼠体外循环模型的建立  中国体外循环杂志  2018  16(03):184-188 
    ZongAn Chen, Lin Zhou, TaeHao Won, Zhen Gao, XiaoLi Wu,  Characterization of CD45RO+ Memory T Lymphocytes in Keloid Disease  British Journal of Dermatology  2017  178(4):940-950 
    Yang J, Ryan DJ, Wang W, Tsang JC, Lan G, Masaki H, Gao X, Antunes L, Yu Y, Zhu Z, Wang J, Kolodziejczyk AA, Campos LS, Wang C, Yang F, Zhong Z, Fu B, Eckersley-Maslin MA, Woods M, Tanaka Y, Chen X, Wilkinson AC, Bussell J, White J, Ramirez-Solis R, Reik W, G?ttgens B, Teichmann SA, Tam PPL, Nakauchi H, Zou X,, Liu P  Establishment of mouse expanded potential stem cells  Nature   2017  550（7676） 
    Zhang D, Zhou J, Tang D, Zhou L, Chou L, Chou KY, Tao L,  Neutrophil infiltration mediated by CXCL5 accumulation in the laryngeal squamous cell carcinoma microenvironment: A mechanism by which tumour cells escape immune surveillance  Clin Immunol  2017  175:34-40 
    万建伟,周琳,赵丹丹,杨玉琴,  联烯化合物PHPO 对肺癌细胞株A549 增殖及凋亡的影响  上海交通大学学报（医学版）  2017  37（10）：1433-1439 
    张晓阳,,李 欣  调节性T细胞和辅助性T细胞与体外循环后肺损伤相关性 的研究  中国体外循环杂志  2017  15（2）：81-84 
    WEIJING TANG, LEI TAO,, DI TANG,XIAOLIN SHI  Role of T helper 17 cytokines in the tumour immune inflammation  ONCOLOGY LETTERS  2017  14（1）: 561-568 
    Zhao AM, Xu HJ, Kang XM, Zhao AM,  New insights into myeloid-derived suppressor cells and their roles in feto-maternal immune cross-talk  J Reprod Immunol  2016  113:35-41 
    Yu Y, Tsang JC, Wang C, Clare S, Wang J, Chen X, Brandt C, Kane L, Campos LS,, Belz GT, McKenzie AN, Teichmann SA, Dougan G, Liu P  Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway  Nature  2016  539(7627):102-106 
    于浩然,张柳蕙,刘威,周琳,丁旭苹,蒋黎华,  RBL教学对临床医学本科生综合能力培养的作用  中华医学教育探索杂志  2016  15.10（2016）；1034-1038 
    Zhou J, Zhang D, Zhou L, Yang Y, Liu F, Tao L,  Association of the recurrence and canceration rate of vocal leukoplakia with interleukin-10 promoter variants over a 2-year period  Acta Oto-Laryngologica  2016  2016 Jun 14:1-7 
    Zhang D, Tang WJ, Tang D, Zhou J, Chou L, Tao L,  The ratio of CD4/CD8 T-cells in human papillomavirus-positive laryngeal squamous cell carcinoma accounts for improved outcome  Acta Otolaryngol   2016  136(8):826-33 
    Zhou J, Yang Y, Zhang D, Zhou L, Liu F, Tao L,  Association of the recurrence of vocal leukoplakia with MDM2-309 variants over a 2-year period: a prospective study  Acta Otolaryngol  2016  136(1):95-9 
    Tang.D, W. J. Tang, X. L. Shi, W. P. Li, H. Zhou,, L. Tao  Association of the microsatellite (GT)n repeat polymorphisms of the HO-1 gene promoter and corresponding serum levels with the risk of laryngeal squamous cell carcinoma  Acta Otolaryngol  2016  136, 806-11 
    周琳,高文,  肺移植后闭塞性细支气管炎免疫学发病机制及治疗新策略  现代免疫学  2016  36(1):67-71 
    Li Z, Yang N, Zhou L, Gu P, Wang H, Zhou Y, Zhou P,, Chou KY  A peptide tetramer Tk-tPN induces tolerance of cardiac allografting by conversion of type 1 to type 2 immune responses via the Toll-like receptor 2 signal-promoted activation of the MCP1 gene  Immunology  2016  147(3):355–366 
    Zhang D, Chen B, Zhou J, Zhou L, Li Q, Liu F, Chou KY, Tao L,  Low concentrations of trichosanthin induce apoptosis and cell cycle arrest via c-Jun N-terminal protein kinase/mitogen-activated protein kinase activation  Mol Med Rep  2015  11(1):349-56 
    Yang J, Wang W, Ooi J, Campos LS,, Liu P   Signalling Through Retinoic Acid Receptors is Required for Reprogramming of Both Mouse Embryonic Fibroblast Cells and Epiblast Stem Cells to Induced Pluripotent Stem Cells  Stem Cells  2015  33(5):1390-404.  
    Jason C. H. Tsang, Yong Yu, Shannon Burke, Florian Buettner, Cui Wang, Aleksandra A. Kolodziejczyk, Sarah A. Teichmann,, and Pentao Liu  Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells  Genome Biology  2015  16(1):178 
    Yu Y, Wang C, Clare S, Wang J, Lee SC, Brandt C, Burke S,, He D, Jenkins NA, Copeland NG, Dougan G, Liu P  The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development  J Exp Med  2015  212(6):865-74 
    Zhou J, Zhang D, Chen B, Li Q, Zhou L, Liu F, Chou KY, Tao L,  Association of interleukin-10 promoter polymorphisms and corresponding plasma levels with susceptibility to laryngeal squamous cell carcinoma  Oncol Lett  2014  7(5):1721-1727 
    Yang N, Li Z, Jiao Z, Gu P, Zhou Y,, Chou KY  A Trichosanthin-derived peptide suppresses type 1 immune responses by TLR2-dependent activation of CD8(+)CD28(-) Tregs  Clin Immunol.  2014  153(2):277-87 
    Jason CH Tsang, Xuefei Gao,, Pentao Liu  Cellular reprogramming by transcription factor engineering  Current Opinion in Genetics & Development  2014  28:1-9 
    Xuefei Gao, Jason C.H. Tsang, Fortis Gaba, Donghai Wu,, Pentao Liu  Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers  Nucleic Acids Research  2014  42（20）：Pp. e155 
    Liu F, Pan X, Zhou L, Zhou J, Chen B, Shi J, Gao W,  Genetic polymorphisms and plasma levels of interleukin-22 contribute to the development of nonsmall cell lung cancer  DNA Cell Biol  2014  33(10):705-14 
    Chen B, Zhang D, Zhou J, Li Q, Zhou L, Li SM, Zhu L, Chou KY, Zhou L, Tao L,  High CCR6/CCR7 expression and Foxp3+ Treg cell number are positively related to the progression of laryngeal squamous cell carcinoma  Oncol Rep  2013  30(3):1380-90 
    周琳 周光炎 路丽明  IL-10 的双向免疫调节作用  细胞与分子免疫学杂志  2012  28(10):1100-1102 
    李青 周光炎 路丽明  天花粉蛋白抑制同种异体混合淋巴细胞反应与诱导IL9+IL10+IL24Th9细胞间关系的初步探讨  现代免疫学  2012  32(2): 94-98 
    Zhiqiang Yang, Peng Gu, Xiaoyi Shao, Zuoqing Li, Yun Zhou,, Kuang-Yen Chou  Mutated MHC class II transactivator upregulates IL-33-dependent differentiation of Th2 subset through Nod2 binding for NLR signaling initiation  J Biological Chemistry  2012  Mar 23;287(13) :9972-9981 
    邵晓轶 周云 路丽明 马妍慧杨志强 周光炎  p38MAPK信号通路在B7H1-Ig融合蛋白诱导Tr1细胞分化中的作用   上海交通大学学报（医学版）  2012  32（11）：1448－1454 
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