• 基本信息
    导师姓名： 赵任 学科代码： 100210
    性别： 男 学科名称： 外科学
    培养单位： 附属瑞金医院 三级学科 普外
    导师类型： 博士生导师 专业领域名称： 外科学 专业学位
    联系方式： zhaorensurgeon@aliyun.com/rjzhaoren@139.com 专业领域代码： 105111
    邮编： rjzhaoren@139.com 邮箱地址： zhaorensurgeon@aliyun.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    中国医师协会结直肠肿瘤专业委员会单孔腹腔镜学组主任委员
    中国医师协会结直肠肿瘤专业委员会机器人学组副主委
    上海交通大学医学院附属瑞金医院副院长
    上海交通大学医学院附属瑞金医院医用机器人研究所所长
    中国医师协会结直肠肿瘤专业委员会快速康复学组副主委
    Fellow of the American College of Surgeons（美国外科学院院士）
    国家卫健委结直肠癌诊疗规范专家组成员
    上海市医师协会结直肠外科学组组长
    中国医师协会肛门直肠疾病分会常委
    上海市抗癌协会副理事长
    中国医师协会外科学分会结直肠专业委员会常委
    中国抗癌协会大肠癌专委会委员
    上海市抗癌协会大肠癌专业委员会主任委员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    82271766HECTD1调控Th17细胞分化介导结直肠炎癌转变的机制国家自然科学基金面上项目 2023-01~2026-12 54万元  课题负责人
    SHDC2020CR1026B单孔腹腔镜与传统腹腔镜结直肠癌根治术肿瘤学疗效的多中心随机对照临床研究申康中心促进市级医院临床及技能及临床创新三年行动计划-重大临床研究项目 2020-10~2023-10 715万元  课题负责人
    2019SY058单孔腹腔镜技术在结直肠手术中应用及推广上海市卫健委 2019-07~2022-06 80万元  课题负责人
    18DZ1910104溶瘤病毒抗肿瘤药物安柯瑞上市后临床再评价研究上海市科学技术委员会 2018-10~2021-10 60万元  课题负责人
    18ZR1424300Cortactin蛋白脯氨酸富集结构域磷酸化修饰在结直肠癌肝转移中的作用与相关机制研究上海市科学技术委员会 2018-06~2021-05 30万元  课题负责人
    16CR3064B减孔腹腔镜和单孔腹腔镜技术在结直肠恶性肿瘤中的临床研究上海市申康中心市级医院临床技能与创新项目 2016-12~2019-06 30万元  课题负责人
    201540026上海市卫计委重点课题优化手术联合放疗治疗局部复发性直肠癌的应用研究 上海市卫计委重点课题 2016-01~2018-12 15万元  课题负责人
    14411950504晚期结直肠癌患者化疗疗效预测上海市科委项目 2014-06~2017-09 10万元  课题负责人
    /伺机性筛查和减孔腹腔镜手术在结直肠肿瘤中的应用上海市申康中心郊区三级医院临床能力建设项目 2013-10~2016-09 15万元  课题负责人
    81272751cortactin及相关肌动蛋白装配在大肠癌休眠/增殖转换中的作用研究国家自然基金委,面上项目 2013-01~2016-12 70万元  课题负责人
    30772106cortactin差异表达与大肠癌转移的相关性研究国家自然基金委,面上项目 2008-01~2010-12 30万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Cao Z, Gao W, Bao H, Feng H, Mei S, Chen P, Gao Y, Cui Z, Zhang Q, Meng X, Gui H, Wang W, Jiang Y, Song Z, Shi Y, Sun J, Zhang Y, Xie Q, Xu Y, Ning G, Gao Y,  VV116 versus Nirmatrelvir-Ritonavir for Oral Treatment of Covid-19.  N Engl J Med  2023  Feb 2;388(5):406-417. 
    Liu J, Pan X, Zhang S, Li M, Ma K, Fan C, Lv Y, Guan X, Yang Y, Ye X, Deng X, Wang Y, Qin L, Xia Z, Ge Z, Zhou Q, Zhang X, Ling Y, Qi T, Wen Z, Huang S, Zhang L, Wang T, Liu Y, Huang Y, Li W, Du H, Chen Y, Xu Y, Zhao Q,, Annane D, Qu J, Chen D.  Efficacy and safety of Paxlovid in severe adult patients with SARS-Cov-2 infection: a multicenter randomized controlled study  Lancet Reg Health West Pac  2023  33:100694. 
    Guo Z, Shi Y, Song Z, Jia W, Wang S, Zhang Y, Ji X, Liu K, Zhang T, Cheng X,  Single-incision robotic assisted surgery: a non-randomized cohort pilot study on a novel surgical platform in colorectal surgery  Int J Surg  2023  Aug 1. 
    Cao Z, Gao Y,  VV116 or Nirmatrelvir-Ritonavir for Oral Treatment of Covid-19. Reply.  N Engl J Med  2023  22;388(25):2396-2397. 
    Li C, Guo Z, Pu S, Zhou C, Cheng X,, Jia N.  Molybdenum Disulfide-Integrated Iron Organic Framework Hybrid Nanozyme-Based Aptasensor for Colorimetric Detection of Exosomes  Biosensors   2023  9;13(8):800 
    Feng H, Guo Z, Chen X, Liu K, Li H, Jia W, Wang C, Luo F, Ji X, Zhang T,, Cheng X.  Excessive HSP70/TLR2 activation leads to remodeling of the tumor immune microenvironment to resist chemotherapy sensitivity of mFOLFOX in colorectal cancer.  Clin Immunol  2022  Dec;245:109157. 
    Zhang Y, Feng H, Wang S, Gu Y, Shi Y, Song Z, Deng Y, Ji X, Cheng X, Zhang T,  Short- and long-term outcomes of robotic- versus laparoscopic-assisted right hemicolectomy: A propensity score-matched retrospective cohort study.  Int J Surg  2022  Sep;105:106855. 
    Shen X, Zhou C, Feng H, Li J, Xia T, Cheng X,, Zou D.  ETV1 Positively Correlated With Immune Infiltration and Poor Clinical Prognosis in Colorectal Cancer.  Front Immunol  2022  Jul 4;13:939806 
    Zhao Q, Feng H, Yang Z, Liang J, Jin Z, Chen L, Zhan L, Xuan M, Yan J, Kuang J, Cheng X,, Qiu W.  The central role of a two-way positive feedback pathway in molecular targeted therapies-mediated pyroptosis in anaplastic thyroid cancer.  Clinical and Translational Medicine  2022  Feb;12(2):e727.  
    Feng Q, Yuan W, Li T, Tang B, Jia B, Zhou Y, Zhang W,, Zhang C, Cheng L, Zhang X, Liang F, He G, Wei Y, Xu J  Robotic versus laparoscopic surgery for middle and low rectal cancer (REAL): short-term outcomes of a multicentre randomised controlled trial.  Lancet Gastroenterol Hepatol  2022  Nov;7(11):991-1004. 
    Li H, Huang H, Zhang T, Feng H, Wang S, Zhang Y, Ji X, Cheng X,  Apatinib: A Novel Antiangiogenic Drug in Monotherapy or Combination Immunotherapy for Digestive System Malignancies.  Front Immunol  2022  Jun 29;13:937307. 
    Guo Z, Ji X, Wang S, Zhang Y, Liu K, Wang C, Deng Y, Zhang T, Cheng X,  Clinical Status and Future Prospects of Transanal Total Mesorectal Excision.  Frontiers in Oncology  2022  Jan 3;11:752737. 
    Wu Z, Huang H, Han Q, Hu Z, Teng XL, Ding R, Ye Y, Yu X,, Wang Z, Zou Q.  SENP7 senses oxidative stress to sustain metabolic fitness and antitumor functions of CD8+ T cells.  J Clin Invest  2022  Apr 1;132(7):e155224. 
    Zhang T, Song Z, Zhang Y, Ji X, Jing X, Shi Y, Cheng X,  Single-docking robotic-assisted artery-guided segmental splenic flexure colectomy for splenic flexure cancer-a propensity score-matching analysis  J Gastrointest Oncol  2021  12(3):944-952. 
    Song ZJ, Shi YQ, Jiang YM, Liu K, Li Y, Wang CG,  Pure transvaginal natural orifice transluminal endoscopic surgery right hemicolectomy for colon cancer: A case report  World J Clin Cases  2021  Mar 6;9(7):1714-1719. 
    Peng Y, Feng H, Wang C, Song Z, Zhang Y, Liu K, Cheng X,  The role of E26 transformation-specific variant transcription factor 5 in colorectal cancer cell proliferation and cell cycle progression  Cell Death Dis  2021  Apr 30;12(5):427. 
    Jiang Y, Ji X, Liu K, Shi Y, Wang C, Li Y, Zhang T, He Y, Xiang M,  Exosomal miR-200c-3p negatively regulates the migraion and invasion of lipopolysaccharide (LPS)-stimulated colorectal cancer (CRC)  BMC Mol Cell Biol  2020  Jun 29;21(1):48.  
    Wang C, Feng H, Cheng X, Liu K, Cai D,  Potential Therapeutic Targets of B7 Family in Colorectal Cancer  Front Immunol  2020  May 5;11:681.  
    Feng H, Jin Z, Liu K, Peng Y, Jiang S, Wang C, Hu J, Shen X, Qiu W, Cheng X,  Identification and validation of critical alternative splicing events and splicing factors in gastric cancer progression  J Cell Mol Med  2020  2020 Sep 16. 
    Feng H, Liu K, Shen X, Liang J, Wang C, Qiu W, Cheng X,  Targeting tumor cell-derived CCL2 as a strategy to overcome Bevacizumab resistance in ETV5 + colorectal cancer  Cell Death Dis  2020  Oct 24;11(10):916 
    Jiang Y, Yan X, Liu K, Shi Y, Wang C, Hu J, Li Y, Wu Q, Xiang M,  Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods  BMC Cancer  2020  2020 Oct 19;20(1):1012.  
    Rahmy S, Cheng X, Wang M, Feng H, Qiu W,, Lu X.  Organ-specific regulation of CHD1 by acute PTEN and p53 loss in mice  Biochem Biophys Res Commun  2020  May 7;525(3):614-619.  
    Cheng X, Jin Z, Ji X, Shen X, Feng H, Morgenlander W, Ou B, Wu H, Gao H, Ye F, Zhang Y, Peng Y, Liang J, Jiang Y, Zhang T, Qiu W, Lu X,  ETS variant 5 promotes colorectal cancer angiogenesis by targeting platelet-derived growth factor BB  International Journal of Cancer  2019  2019 Jan 16. doi: 10.1002/ijc.32071. 
    Shi Y, Song Z, Gu Y, Zhang Y, Zhang T,  Short-Term Outcomes of Three-Port Laparoscopic Right Hemicolectomy Versus Five-Port Laparoscopic Right Hemicolectomy: With a Propensity Score Matching Analysis  J Invest Surg  2019  Apr 4;1-6. 
    Jiang Y, Song Z, Cheng X, Liu K, Shi Y, Wang C, Li Y, Ji X,  Clinical and oncological outcomes of single-incision vs. conventional laparoscopic surgery for rectal cancer  Surg Endosc   2019  Dec 19. doi: 10.1007/s00464-019-07317-5. 
    Jing X, Wang XJ, Zhang T, Zhu W, Fang Y, Wu H, Liu X, Ma D, Ji X, Jiang Y, Liu K, Chen X, Shi Y, Zhang Y, Shi M, Qiu W,  Cell-Cycle-Dependent Phosphorylation of PRPS1 Fuels Nucleotide Synthesis and Promotes Tumorigenesis  Cancer Research  2019  2019 Sep 15;79(18):4650-4664 
    Feng S, Cheng X, Zhang L, Lu X, Chaudhary S, Teng R, Frederickson C, Champion MM,, Cheng L, Gong Y, Deng H, Lu X.  Myeloid-derived suppressor cells inhibit T cell activation through nitrating LCK in mouse cancers.  Proc Natl Acad Sci U S A(PNAS)  2018  2018 Oct 2;115(40):10094-10099 
    Wu HX, Cheng X, Jing XQ, Ji XP, Chen XZ, Zhang YQ, He YG, Liu K, Ye F, Sun HX, Gao HJ, Song ZJ, Wu H, Zhang XJ, Zhang T,  LIFR promotes tumor angiogenesis by up-regulating IL-8 levels in colorectal cancer  Biochim Biophys Acta  2018  2018 Sep;1864(9 Pt B):2769-2784. 
    Cheng X, Feng H, Wu H, Jin Z, Shen X, Kuang J, Huo Z, Chen X, Gao H, Ye F, Ji X, Jing X, Zhang Y, Zhang T, Qiu W,  Targeting autophagy enhances apatinib-induced apoptosis via endoplasmic reticulum stress for human colorectal cancer  Cancer Letters  2018  2018 Sep 1;431:105-114 
    Jing X, Wu H, Cheng X, Chen X, Zhang Y, Shi M, Zhang T, Wang X,  MLLT10 promotes tumor migration, invasion, and metastasis in human colorectal cancer.  Scand J Gastroenterol  2018  53(8):964-971. 
    Song Z, Li Y, Liu K, Jiang Y, Shi Y, Ji X, Zhang T, Wu H, Shi Y,  Clinical and oncologic outcomes of single-incision laparoscopic surgery for right colon cancer: a propensity score matching analysis.  Surgical Endoscopy  2018  2018 Jul 24. doi: 10.1007/s00464-018-6370-2 
    Cheng X, Wu H, Jin ZJ, Ma D, Yuen S, Jing XQ, Shi MM, Shen BY, Peng CH,, Qiu WH.  Up-regulation of chemokine receptor CCR4 is associated with Human Hepatocellular Carcinoma malignant behavior  Scientific Reports  2017  7(1):12362. 
    Deng Yanhong ,Chi Pan,Lan Ping,Wang Lei,Chen Weiqing,Cui Long,Chen Daoda,Cao Jie,Wei Hongbo,Peng Xiang,Huang Zonghai,Cai Guanfu,,Huang Zhongcheng,Xu Lin,Zhou Hongfeng,Wei Yisheng,Zhang Hao,Zheng Jian,Huang Yan,Zhou Zhiyang,Cai Yue,Kang Liang,Huang Meijin,Peng Junsheng,Ren Donglin,Wang Jianping   Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial  Journal of Clinical Oncology  2016  34 (27）：3300 
    Wang Zhenlei ,Ma Bin,Ji Xiaopin,Deng Yang,Zhang Tao,Zhang Xiaojian,Gao Haoji,Sun Hanxing,Wu Haoxuan,Chen Xianze,  MicroRNA (*) -378-5p suppresses cell proliferation and induces apoptosis in colorectal cancer cells by targeting BRAF  Cancer Cell International  2015  15：40 
    Jiang Yimei ,Ji Xiaopin,Zhao Shengguang,Jin Yening,  Laparoscopic Resection with Intraoperative Radiotherapy for Local Advanced Rectal Cancer: A Preliminary Case Report  JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES  2013  23（3）：267~270 
    Ji X1, Li J, Zhu L, Cai J, Zhang J, Qu Y, Zhang H, Liu B,, Zhu Z.  CHD1L promotes tumor progression and predicts survival in colorectal carcinoma.  Journal of Surgical Research  2013  185(1):84-91 
    Yimei J,,Lu X,Huan Z,  A comparison between the reference values of MRI and EUS and their usefulness to surgeons in rectal cancer  Rev Med Pharmacol Sci  2012  16 (15): 2069-2077 
    ,Zhu Jianwei,Ji Xiaopin,Cai Jianhua,Wan Fangjun,Li Qing,Zhong Baoliang,Tucker Steven,Wang Daoyuan,  A Phase II Study of Irinotecan and Capecitabine for Patients with Unresectable Liver-only Metastases from Colorectal Cancer  JAPANESE JOURNAL OF CLINICAL ONCOLOGY  2010  40（1）：10~16