• 基本信息
    导师姓名： 方贻儒 学科代码： 100205
    性别： 男 学科名称： 精神病与精神卫生学
    培养单位： 附属精神卫生中心 三级学科
    导师类型： 博士生导师 专业领域名称： 精神病与精神卫生学 专业学位
    联系方式： 上海市 徐汇区 宛平南路600号 yirufang@aliyun.com 专业领域代码： 105105
    邮编： 200030 邮箱地址： yirufang@aliyun.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    海峡两岸医药卫生交流协会精神卫生和精神病学专委会 常委
    国家卫计委住院医生规范化培训规划教材《精神病学》 主编
    中国神经科学学会 常务理事
    上海市“精品课程”教材《精神病学》 主编
    上海市医师协会精神科医师分会 会长
    中华医学会精神医学分会(CSP) 副主任委员
    中国医师协会精神科医师分会 常委
    中华精神科杂志副总编 / 中国神经精神疾病杂志副主编 / 上海交大学报医学版编委
    J Affect Disord / N Bulletin / Intl J Bipolar Disord / Gen Psychiatry: Editor Member
    中国双相障碍协作组 组长
    国家自然基金委员会第14届专家评审组 二审专家
    中国科学院脑与智能卓越创新中心 客座教授
    上海市重性精神病重点实验室学术委员会 委员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    SHDC2020CR6023抑郁障碍特色专病队列数据库建设上海市精神卫生中心临床研究中心 2020-12~2022-09 187万元  课题负责人
    81930033PKC激活效应在抑郁症免疫炎症机制中的作用探究国家自然科学基金委员会 重点项目 2020-01~2024-12 297万元  课题负责人
    CRC2018DSJ01-1双相障碍与氧化应激损伤机制——基于机器学习的临床大数据分析SMHC临床研究中心 2018-12~2019-11 20万元  课题负责人
    CRC2018ZD02中国汉族人群双相障碍家系队列遗传研究SMHC临床研究中心 2018-12~2022-11 200万元  课题负责人
    8177051078PRKCB1对免疫炎症因子的调控效应及其与抑郁障碍的关系探究国家自然科学基金 2018-01~2021-12 54万元  课题负责人
    2016YFC1307100基于抑郁障碍临床病理特征的多维度诊断、个体化治疗及管理技术科技部：国家重点研发计划，重大慢性非传染性疾病防控研究 2016-09~2020-12 566万元  课题负责人
    SHDC12015131心情温度计——心境障碍早期识别与治疗管理前沿技术的开发与应用上海申康医院发展中心市级医院新兴前沿技术联合攻关项目 2016-01~2018-12 50万元  课题负责人
    SHDC12015302基于移动医疗平台的心境障碍综合防治模式研发与应用上海申康医院发展中心慢性病综合防治项目 2015-12~2018-11 15万元  课题负责人
    NO上海市精神疾病临床医学中心上海市卫计委 2014-01~2018-12 400万元  课题负责人
    91232719TNF-α基因多态性调节抑郁障碍认知功能损害的脑网络机制研究国家自然科学基金委员会“情感和记忆的神经环路基础”重大研究计划 2013-01~2015-12 70万元  课题负责人
    2012BAI01B04抑郁和焦虑障碍规范化干预技术的研发与优化研究“十二五”国家科技支撑项目 2012-01~2014-12 283万元  课题负责人
    2011-873国家临床重点专科-上海市精神卫生中心卫生部 2011-01~2013-12 1000万元  课题负责人
    30971047miRNA调控通路在双相障碍病理机制中作用探究国家自然科学基金委员会面上项目 2010-01~2012-12 30万元  课题负责人
    沪交医科【2008】－6临床精神病学上海交通大学医学院“重点学科建设” 2008-01~2011-12 40万元  课题负责人
    2006AA02Z430亚综合征抑郁遗传与环境病因学探讨及评价指标体系构建国家高技术研究发展计划（863计划） 2007-01~2008-12 90万元  课题负责人
    064119533难治性抑郁症的优化治疗方案研究上海市科委“登山行动计划” 2006-01~2008-12 15万元  课题负责人
    2004BA720A21-02难治性抑郁症的临床特征及治疗方案优化研究“十五”国家科技攻关项目, 科技部 2005-01~-2007-12 100万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Zhao J#, Liu H#, Wu Z, Wang Y, Cao T, Lyu D, Huang Q, Wu Z, Zhu Y, Wu X, Chen J, Wang Y, Su Y, Zhang C, Peng D, Li Z, Rong H, Liu T, Xia Y, Hong W*,  inical features of the patients with major depressive disorder co-occurring insomnia and hypersomnia symptoms: a report of NSSD study  Sleep medicine  2021  81:375-81 
    Zhou R, Chen J, Zhao G, Wang Z, Peng D, Xia W, Mao R, Xu J, Wang F, Zhang C, Wang Y, Yuan C, Su Y, Huang J, Yang T, Wang C, Cui L, Wang J,, Fang Y*  Neural biomarker of functional disability in major depressive disorder: A structural neuroimaging study  Progress in neuro-psychopharmacology & biological psychiatry  2021  111:110337 
    Li HJ#, Zhang C#, Hui L, Zhou DS, Li Y, Zhang CY, Wang C, Wang L, Li W, Yang Y, Qu N, Tang J, He Y, Zhou J, Yang Z, Li X, Cai J, Yang L, Chen J, Fan W, Tang W, Tang W, Jia QF, Liu W, Zhuo C, Song X, Liu F, Bai Y, Zhong BL, Zhang SF, Chen J, Xia B, Lv L, Liu Z, Hu S, Li XY, Liu JW, Cai X, Yao YG, Zhang Y, Yan H, Chang S, Zhao JP, Yue WH, Luo XJ, Chen X, Xiao X,, Li M*  Novel Risk Loci Associated with Genetic Risk for Bipolar Disorder Among Han Chinese Individuals: A Genome-Wide Association Study and Meta-analysis  JAMA Psychiatry  2021  78(3):320-30 
    Hu G, Yu S, Yuan C, Hong W, Wang Z, Zhang R, Wang D, Li Z, Yi Z,  Gene expression signatures differentiating major depressive disorder from subsyndromal symptomatic depression  Aging  2021  13(9):13124-37 
    Zhu Y, Liu L, Yang D, Ji H, Huang T, Xue L, Jiang X, Li K, Tao L, Cai Q,  Cognitive control and emotional response in attention-deficit/hyperactivity disorder comorbidity with disruptive, impulse-control, and conduct disorders  BMC psychiatry  2021  21(1):232 
    Huang L#, Huang R, Fei Y, Liu T, Mellor D, Xu W, Xiong J, Mao R, Chen J,, Wu Z*, Wang Z*  Lower Health Literacy of Mania Than Depression Among Older People: A Random Survey of a Community Healthcare Service Center  Frontiers in psychiatry  2021  12 
    Huang J, Cai Y, Su Y, Zhang M, Shi Y, Zhu N, Jin F, Peng D*,  Gastrointestinal Symptoms During Depressive Episodes in 3256 Patients with Major Depressive Disorders: Findings from the NSSD  J Affect Disord  2021  286:27-32 
    Chen J, Wang Z, Li Z, Peng D,  Disturbances of affective cognition in mood disorders  Science China Life sciences  2021  64(6):938-41 
    Li Z, Ruan M, Chen J,  Major Depressive Disorder: Advances in Neuroscience Research and Translational Applications  Neuroscience bulletin  2021  37(6):863-880 
    Shi Y, Tang Y, Wu Z, Chen J, Huang J,  Schizophrenia, bipolar disorder, or intracranial aneurysm? A case report  Brain and behavior  2021  / 
    Yang T, Frangou S, Lam RW, Huang J, Su Y, Zhao G, Mao R, Zhu N, Zhou R, Lin X, Xia W, Wang X, Wang Y, Peng D, Wang Z, Yatham LN*, Chen J*,  Probing the clinical and brain structural boundaries of bipolar and major depressive disorder  Translational psychiatry  2021  11(1):48 
    Guo X, Mao R, Cui L, Wang F, Zhou R, Wang Y, Huang J, Zhu Y, Yao Y, Zhao G, Li Z, Chen J, Wang J,  PAID study design on the role of PKC activation in immune/inflammation-related depression: a randomized placebo-controlled trial protocol  General psychiatry  2021  34(2): e100440 
    Chen Y, Magnin C, Brunelin J, Leaune E,  Can seizure therapies and noninvasive brain stimulations prevent suicidality? A systematic review  Brain and behavior  2021  11(5): e02144 
    Wang Y, Liu X, Peng D, Wu Y, Su Y, Xu J, Ma X, Li Y, Shi J, Cheng X, Rong H,  A preliminary randomized controlled trial of different treatment regimens for melancholic depression  Neuropsychiatric disease and treatment  2021  17:2441–2449 
    Wang XQ, Zhang L, Xia ZY, Chen JY,, Ding YQ*  PTEN in prefrontal cortex is essential in regulating depression-like behaviors in mice  Translational psychiatry  2021  11(1):185 
    Yang L, Wu Z, Cao L, Wang Y, Su Y, Huang J, Fang M, Yao Z, Wang Z, Wang F, Zhu Y, Wang Y, Chen J, Peng D,  Predictors and moderators of quality of life in patients with major depressive disorder: An AGTs-MDD study report  J Psychiatr Res  2021  138:96-102 
    Yang T, Lam RW, Huang J, Su Y, Liu J, Yang X, Yang L, Zhu N, Zhao G, Mao R, Zhou R, Xia W, Liu H, Wang Z, Chen J*,  Exploring the Effects of Temperament on Gray Matter Volume of Frontal Cortex in Patients with Mood Disorders  Neuropsychiatric disease and treatment  2021  17:183-93 
    Zhu Y#, Wu X#, Zhou R, Sie O, Niu Z, Wang F*,  Hypothalamic-Pituitary-End-Organ Axes: Hormone Function in Female Patients with Major Depressive Disorder  Neuroscience bulletin  2021  37: 1176–1187 
    Lin X, Zhou RB, Huang J, Su YS, Mao RZ, Niu ZA, Cao L, Hu YY, Yang T, Wang X, Zhao GQ, Wang Y, Peng DH, Wu ZG, Wang ZW, Yuan CM, Chen J*,  Altered resting-state fMRI signals and network topological properties of bipolar depression patients with anxiety symptoms  J Affect Disord  2020  277:358-67 
    Wang F, Wu X, Gao J, Li Y, Zhu Y*,  The relationship of olfactory function and clinical traits in major depressive disorder  Behavioural brain research  2020  386:112594 
    Zhu Y, Wu Z, Sie O, Cai Y, Huang J, Liu H, Yao Y, Niu Z, Wu X, Shi Y, Zhang C, Liu T, Rong H, Yang H, Peng D,  Causes of drug discontinuation in patients with major depressive disorder in China  Progress in neuro-psychopharmacology & biological psychiatry  2020  96:109755 
    Cui L, Wang C, Wu Z, Peng D, Huang J, Zhang C, Huang J, Hong W, Wang Y, Chen J, Liu T, Rong H, Yang H,  Symptomatology differences of major depression in psychiatric versus general hospitals: A machine learning approach  J Affect Disord  2020  260:349-60 
    Zhu Y, Ji H, Tao L, Cai Q, Wang F, Ji W, Li G,  Functional Status of Hypothalamic-Pituitary-Thyroid and Hypothalamic-Pituitary-Adrenal Axes in Hospitalized Schizophrenics in Shanghai  Frontiers in psychiatry  2020  11:65 
    Wang F, Yu S, Zhou R, Mao R, Zhao G, Guo X, Xu Q, Chen J, Zhang C,  Variants in the Upstream Region of the Insulin Receptor Substrate-1 Gene Is Associated with Major Depressive Disorder in the Han Chinese Population  Neuropsychiatric disease and treatment  2020  16:501-7 
    Chen Y, Hong W,  Role of biological rhythm dysfunction in the development and management of bipolar disorders: a review  General psychiatry  2020  33(1): e100127 
    Geng R, Li Z, Yu S, Yuan C, Hong W, Wang Z, Wang Q, Yi Z*,  Weighted gene co-expression network analysis identifies specific modules and hub genes related to subsyndromal symptomatic depression  The world journal of biological psychiatry  2020  21(2):102-10 
    Liu X, Wang Y, Peng D, Zhang H, Zheng Y, Wu Y, Su YA, Liu M, Ma X, Li Y, Shi J, Cheng X, Rong H,  The Developmental and Translational Study on Biomarkers and Clinical Characteristics-based Diagnostic and Therapeutic Identification of Major Depressive Disorder: Study Protocol for a Multicenter Randomized Controlled Trial in China  Neuropsychiatric disease and treatment  2020  16:2343-51 
    Zhang W, Zhu N#, Lai J, Liu J, Ng CH, Chen J, Qian C, Du Y, Hu C, Chen J, Hu J, Wang Z, Zhou H, Xu Y,, Shi C*, Hu S*  Reliability and Validity of THINC-it in Evaluating Cognitive Function of Patients with Bipolar Depression  Neuropsychiatric disease and treatment  2020  16:2419-28 
    Yao Y, Ju P, Liu H, Wu X, Niu Z, Zhu Y, Zhang C,  Ifenprodil rapidly ameliorates depressive-like behaviors, activates mTOR signaling and modulates pro-inflammatory cytokines in the hippocampus of CUMS rats  Psychopharmacology  2020  237(5):1421-33 
    Wang Y, Wang G, Zhang N, Huang J, Wu W, Jia F, Liu T, Gao C, Hu J, Hong W,  Association between residual symptoms and social functioning in patients with depression  Comprehensive psychiatry  2020  98:152164 
    Guo X, Rao Y, Mao R, Cui L,  Common cellular and molecular mechanisms and interactions between microglial activation and aberrant neuroplasticity in depression  Neuropharmacology  2020  181:108336 
    Yang T, Chen J, Lam RW*,, Xu Y*  Mental Health Service Challenges during the Early Stage of the COVID-19 Pandemic: Experience and Best Practices from China  Canadian journal of psychiatry  2020  66(7) 
    Liu H, Yao Y, Liu H, Peng Y, Ren J, Wu X, Mao R, Zhao J, Zhu Y, Niu Z, Yang T, Sun X, Jiang P, Zhang C,  Lack of Association Between PLA2G6 Genetic Variation and Parkinson's Disease: A Systematic Review  Neuropsychiatric disease and treatment  2020  16:1755-63 
    Zhu Y, Chen L, Ji H, Xi M,, Li Y*  The Risk and Prevention of Novel Coronavirus Pneumonia Infections Among Inpatients in Psychiatric Hospitals  Neuroscience bulletin  2020  36(3):299-302 
    Liang X, Zhu Y*,  COVID-19 and post-traumatic stress disorder: A vicious circle involving immunosuppression  CNS neuroscience & therapeutics  2020  26(8):876-8 
    Zhang Y, Wang X, Li X, Xi D, Mao R, Wu X, Cheng S, Sun X, Yi C, Ling Z, Ma L, Ning Q,, Sun B, Wu D  Potential contribution of increased soluble IL-2R to lymphopenia in COVID-19 patients  Cellular & Molecular Immunology  2020  17: 878–880 
    Lyu D, Wu Z, Wang Y, Huang Q, Wu Z, Cao T, Zhao J, Cao Y, Hu Y, Chen J, Wang Y, Su Y, Zhang C, Peng D, Li Z, Cao L, Hong W*,  Disagreement and factors between symptom on self-report and clinician rating of major depressive disorder: A report of a national survey in China  J Affect Disord  2019  253:141-6 
    Jiang X, Zhu Y,  Response Inhibition and Emotional Regulation in the Patients with Attention-Deficit/Hyperactivity Disorder and Comorbidity of Disruptive, Impulse-Control, and Conduct Disorder  Psychiatry investigation  2019  16(11):872-4 
    Niu Z#, Yang L#, Wu X, Zhu Y, Chen J*,  The Relationship Between Neuroimmunity and Bipolar Disorder: Mechanism and Translational Application  Neuroscience bulletin  2019  35(4):595-607 
    Wang Z, Jun C, Gao K, Yang H,  Perspective on Etiology and Treatment of Bipolar Disorders in China: Clinical Implications and Future Directions  Neuroscience bulletin  2019  35(4):608-12 
    Liao L, Wu Z, Mellor D, Peng D, Zhang C, Xu J, Wang C, Cui L,  Subtypes of treatment-resistant depression determined by a latent class analysis in a Chinese clinical population.  J Affect Disord  2019  249:82-9 
    Zhou Q#, Wu Z, Wang Y, Liu X, Chen J, Wang Y, Su Y, Zhang C, Peng D, Hong W*,  Clinical characteristics associated with therapeutic nonadherence of the patients with major depressive disorder: A report on the National Survey on Symptomatology of Depression in China  CNS neuroscience & therapeutics  2019  25(2):215-22 
    Fang X, Zhang C, Wu Z, Peng D, Xia W, Xu J, Wang C, Cui L, Huang J,  The association between somatic symptoms and suicidal ideation in Chinese first-episode major depressive disorder  J Affect Disord  2018  2018 Oct 17; 245:17-21. doi: 10.1016/j.jad.2018.10.110. [Epub ahead of print] 
    Wang Z, Chen J, Yang H, Ma Y, Meron D, Liu T, Yu X,  Assessment and management of bipolar disorder: Principal summary of updated Chinese guidelines  Bipolar disorders  2018  20(3):289-292 
    Shen H, Zhang L, Xu C, Zhu J, Chen M,  Analysis of misdiagnosis of bipolar disorder in an outpatient setting  Shanghai archives of psychiatry  2018  30(2):93-101 
    Mao R, Zhang C, Chen J, Zhao G, Zhou R, Wang F, Xu J, Yang T, Su Y, Huang J, Wu Z, Cao L, Wang Y, Hu Y, Yuan C, Yi Z, Hong W, Wang Z, Peng D,  Different levels of pro- and anti-inflammatory cytokines in patients with unipolar and bipolardepression  J Affect Disord  2018  2018 Sep; 237: 65-72. doi: 10.1016/j.jad.2018.04.115. 
    Huang J, Wang Y, Chen J, Zhang Y, Yuan Z, Yue L, Haro JM, Moneta MV, Novick D,  Clinical outcomes of patients with major depressive disorder treated with either duloxetine, escitalopram, fluoxetine, paroxetine, or sertraline  Neuropsychiatr Dis Treat  2018  2018 Sep 26; 14:2473-2484. doi: 10.2147/NDT.S159800. eCollection 2018. 
    Zhao D, Wu Z, Zhang H, Mellor D, Ding L, Wu H, Wu C, Huang J, Hong W, Peng D,  Somatic symptoms vary in major depressive disorder in China  Compr Psychiatry  2018  2018 Nov; 87:32-37. doi: 10.1016/j.comppsych.2018.08.013. Epub 2018 Aug 28. 
    Yang T, Zhao G, Mao R, Huang J, Xu X, Su Y, Zhu N, Zhou R, Lin X, Xia W, Wang F, Liu R, Wang X, Huang Z, Wang Y, Hu Y, Cao L, Yuan C, Wang Z, Lam RW, Chen J,  The association of duration and severity of disease with executive function: Differences between drug-na?ve patients with bipolar and unipolar depression  J Affect Disord  2018  2018 May 29; 238: 412-417. doi: 10.1016/j.jad.2018.05.051. 
    Geng R, Li Z, Yu S, Yuan C, Hong W, Wang Z, Wang Q, Yi Z,  Weighted gene co-expression network analysis identifies specific modules and hub genes related to subsyndromal symptomatic depression  World J Biol Psychiatry  2018  2018 Nov 29:1-23. doi: 10.1080/15622975.2018.1548782. [Epub ahead of print] 
    Wang P, Lv Q, Mao Y, Zhang C, Bao C, Sun H, Chen H, Yi Z, Cai W,  HTR1A/1B DNA methylation may predict escitalopram treatment response in depressed Chinese Han patients  J Affect Disord  2018  228:222-228 
    Zhou R, Wang F, Zhao G, Xia W, Peng D, Mao R, Xu J, Wang Z, Hong W, Zhang C, Wang Y, Su Y, Huang J, Yang T, Wang J, Chen J, Palaniyappan L,  Effects of tumor necrosis factor-α polymorphism on the brain structural changes of the patientswith major depressive disorder  Transl Psychiatry  2018  2018 Oct 11;8(1):217. doi: 10.1038/s41398-018-0256-x. 
    Fang X#, Zhang C*, Wu Z, Peng D, Xia W, Xu J, Wang C, Cui L, Huang J,  Prevalence, risk factors and clinical characteristics of suicidal ideation in Chinese patients with depression  J Affect Disord  2018  235:135-141 
    Fang X, Zhang C, Wu Z, Peng D, Xia W, Xu J, Wang C, Cui L, Huang J,  Prevalence, risk factors and clinical characteristics of suicidal ideation in Chinese patients with depression  J Affect Disord  2018  2018 Aug 1; 235: 135-141. doi: 10.1016/j.jad.2018.04.027. 
    Wu Z, Cao L, Peng D, Mellor D, Zhang C, Li H, Wang Z, Song Y, Li C,  The clinical correlates of comorbid anxiety symptoms and syndromal anxiety in patients with major depressive disorder  Psychiatry Res  2018  2018 Aug 28; 269: 251-257. doi: 10.1016/j.psychres. 2018.07.019. [Epub ahead of print] 
    Wang Z, Chen J, Yang H, Ma Y, Meron D, Liu T, Yu X,  Assessment and management of bipolar disorder: Principal summary of updated Chinese guidelines  Bipolar Disord  2018  2018 May; 20(3): 289-292. doi: 10.1111/bdi.12646. 
    Huang J, Yuan CM, Xu XR, Wang Y, Hong W, Wang ZW, Su YS, Hu YY, Cao L, Wang Y, Chen J,  The relationship between lifestyle factors and clinical symptoms of bipolar disorder patients in a Chinese population  Psychiatry Res  2018  2018 Aug; 266: 97-102. doi: 10.1016/j.psychres.2018.04.059. 
    Xia W, Zhou R, Zhao G, Wang F, Mao R, Peng D, Yang T, Wang Z, Chen J,  Abnormal whitematter integrity in Chinese young adults with first-episode medication-free anxious depression: a possible neurological biomarker of subtype major depressive disorder  Neuropsychiatr Dis Treat  2018  2018 Aug 10; 14: 2017-2026. doi: 10.2147/NDT.S169583. eCollection 2018. 
    Chengqing Yang, Guoqin Hu, Zezhi Li, Qingzhong Wang, Xuemei Wang, Chengmei Yuan, Zuowei Wang, Wu Hong, Weihong Lu, Lan Cao1, Jun Chen, Yong Wang, Shunying Yu,, Zhenghui Yi, Yiru Fang*  Differential gene expression in patients with subsyndromal symptomatic depression and major depressive disorder  PLOS ONE  2017  https://doi.org/10.1371/journal.pone.0172692 March 23, 2017. 
    Hu Y, Hong W, Smith A, Yu S, Li Z, Wang D, Yuan C, Cao L, Wu Z, Huang J, Fralick D, Phillips MR,  Association analysis between mitogen-activated protein/extracellular signal-regulated kinase (MEK) gene polymorphisms and depressive disorder in the Han Chinese population  J Affect Disord  2017  2017 Nov; 222: 120-125. doi: 10.1016/j.jad.2017.06.059. 
    Zezhi Li, Zuowei Wang, Chen Zhang,Jun Chen, Yousong Su, Jia Huang, Zhenghui Yi,Chengmei Yuan, Wu Hong, Yong Wang, Zhiguo Wu, Yingyan Hu, Lan Cao, Daihui Peng,Yangtai Guan, Yimin Zou, Shunying Yu, Donghong Cui,  Reduced ENA78 levels as novel biomarker for major depressive disorder and venlafaxine efficiency: Result from a prospective longitudinal study  Psychoneuroendocrinology  2017  2017;81:113-121. 
    Chen Zhang,Dengfeng Zhang,Zhiguo Wu,Daihui Peng,Jun Chen,Jianliang Ni,Wenxin Tang,Lin Xu,Yonggang Yao,  Complement factor H and susceptibility to majordepressive disorder in Han Chinese  The British Journal of Psychiatry  2016  208（5）：446-452.doi: 10.1192/bjp.bp.115.163790. 
    GuoqingZhao,ChenZhang,JunChen,YousongSu,RubaiZhou,Fan Wang, Weiping Xia,Jia Huang,ZuoweiWan,YingyanHu,LanCao,Xiaoyun Guo, ChengmeiYuan,YongWang,ZhenghuiY,WeihongLu,YanWu,ZhiguoWu, Wu Hon,Daihui Peng,  Ratio of mBDNF toproBDNF for Differential DiagnosisofMajor Depressive Disorder and Bipolar Depression  molecular neurobiology  2016  54(7):5573–5582 
    Chen Zhang, Zuowei Wang, Wu Hong, Zhiguo Wu, Daihui Peng,  ZNF804A Genetic Variation Confers Risk to Bipolar Disorder  Molecular Neurobiology  2016  53(5):2936-2943 .DOI:10.1007/s12035-015-9193-3 
    Chen Zhang,Weihong Lu,Zuowei Wang,Jianliang Ni,Jiangtao Zhang,Wenxin Tang,  A comprehensive analysis of NDST3 for schizophrenia and bipolar disorder in Han Chinese  Translational Psychiatry  2016  6：e701. doi: 10.1038/tp.2015.199. 
    Daihui Peng, Ting Shen, Linda Byrne, Chen Zhang, Yueqi Huang, Xin Yu, Jingping Zhao, Marita McCabe, David Mellor,  Atypical features and treatment choices in bipolar disorders: a result of the National Bipolar Mania Pathway Survey in China  Neuroscience Bulletin  2015  01/2015; 31(1):22-30.DOI:10.1007/s12264-014-1487-3 
    Daihui Peng, Feng Shi, Gang Li, Drew Fralick, Ting Shen, Meihui Qiu, Jun Liu, Kaida Jiang, Dinggang Shen,  Surface Vulnerability of Cerebral Cortex to Major Depressive Disorder  PLoS ONE  2015  03/2015; 10(3):e0120704. DOI:10.1371/journal.pone.0120704 
    Haozhe Li, Wu Hong, Chen Zhang, Zhiguo Wu, Zuowei Wang, Chenmei Yuan, Zezhi Li, Jia Huang, Zhiguang Lin,  IL-23 and TGF-β1 levels as potential predictive biomarkers in treatment of bipolar I disorder with acute manic episode  Journal of Affective Disorders361-366.  2015  174:361-366 
    Zuowei Wang, Jun Chen, Chen Zhang, Keming Gao, Wu Hong, Mengjuan Xing, Zhiguo Wu, Chengmei Yuan, Jia Huang, Daihui Peng, Yong Wang, Weihong Lu, Zhenghui Yi, Xin Yu, Jingping Zhao,  Guidelines concordance of maintenance treatment in euthymic patients with bipolar disorder: Data from the national bipolar mania pathway survey (BIPAS) in mainland China  Journal of Affective Disorders  2015  04/2015; 182:101-105.DOI:10.1016/j.jad.2015.04.028 
    Chengmei Yuan, Jia Huang, Keming Gao, Zhiguo Wu, Jun Chen,Yong Wang, Wu Hong, Zhenghui Yi, Yingyan Hu, Lan Cao, Zezhi Li, Kareen K. Akiskal, Hagop S. Akiskal, Biao Wang,  Validation of the Chinese Version of the Short TEMPS-A and its application in patients with mood disorders  Journal of Affective Disorders. 01/2015; 170:178–184.  2015  170(1):178-184 
    Xiaoyun Guo,Zezhi LI,Chen Zhang,Zhenghui Yi,Haozhe LI,Lan Cao,Chengmei Yuan,Wu Hong,Zhiguo Wu,Daihui Peng,Jun Chen,Weiping Xia,Guoqing Zhao,Fan Wang,Shunying Yu,Donghong Cui,Yifeng Xu,Chowdhury M.I. Golam,Alicia K. Smith,Tong Wang,  Down-regulation of PRKCB1 expression in Han Chinese patients with subsyndromal symptomatic depression  Journal of Psychiatric Research  2015  69：1-6. doi: 10.1016/j.jpsychires.2015.07.011.  
    Daihui Peng, Elizabeth B. Liddle, Sarina J Iwabuchi, Chen Zhang, Zhiguo Wu, Jun Liu, Kaida Jiang, Lin Xu, Peter F Liddle, Lena Palaniyappan,  Dissociated large-scale functional connectivity networks of the precuneus in medication-na?ve first-episode depression  Psychiatry Research : Neuroimaging  2015  01/2015; 232(3):250-256. DOI:10.1016/j.pscychresns.2015.03.003 
    Chen Zhang,, Lin Xu  Glutamate receptor 1 phosphorylation at serine 845 contributes to the therapeutic effect of olanzapine on schizophrenia-like cognitive impairments  Schizophrenia Research  2014  07():054- 
    Yi Zhang, Meijuan Chen, Jun Chen, Zhiguo Wu, Shunying Yu,, Chen Zhang  Metabolic syndrome in patients taking clozapine: prevalence and influence of catechol-O-methyltransferase genotype  Psychopharmacology (Berl)  2014  231(10):2211-2218 
    Daihui Peng, Feng Shi, Ting Shen, Ziwen Peng, Chen Zhang, Xiaohua Liu, Meihui Qiu, Jun Liu, Kaida Jiang,, Dinggang Shen  Altered brain network modules induce helplessness in major depressive disorder  Journal of Affective Disorders 01/2014; 168:21–29  2014  168():21-29 
    Chen Zhang, Jiangtao Zhang, Juan Fan, Wenhong Cheng, Yasong Du, Shunying Yu,  Identification of ANKK1 rs1800497 variant in schizophrenia: New data and meta-analysis  American Journal of Medical Genetics Part B Neuropsychiatric Genetics  2014  165(7):564-571 
    Wu Hong, Jinbo Fan, Chengmei Yuan, Chen Zhang, Yingyan Hu, Daihui Peng, Yong Wang, Jia Huang, Zezhi Li, Shunying Yu, Xiaohua Liu, Zhiguo Wu, Jun Chen, Zhenghui Yi, Lin Xu,  Significantly decreased mRNA levels of BDNF and MEK1 genes in treatment-resistant depression  Neuroreport   2014  25():753-755 
    Zuowei Wang, Keming Gao, Wu Hong, Mengjuan Xing, Zhiguo Wu, Jun Chen, Chen Zhang, Chengmei Yuan, Jia Huang, Daihui Peng, Yong Wang, Weihong Lu, Zhenghui Yi, Xin Yu, Jingping Zhao,  Pharmacotherapy for acute mania and disconcordance with treatment guidelines: bipolar mania pathway survey (BIPAS) in mainland China  BMC Psychiatry  2014  14(1):167- 
    Chen Zhang, Jun Cai, Jiangtao Zhang, Zezhi Li, Zhongwei Guo, Xu Zhang, Weihong Lu, Yi Zhang, Aihua Yuan, Shunying Yu,  Genetic modulation of working memory deficits by ankyrin 3 gene in schizophrenia  Prog Neuropsychopharmacol Biol Psychiatry  2014  50():110-115 
    Zuowei Wang, Keming Gao, Wu Hong, Mengjuan Xing, Zhiguo Wu, Jun Chen, Chen Zhang, Chengmei Yuan, Jia Huang, Daihui Peng, Yong Wang, Weihong Lu, Zhenghui Yi, Xin Yu, Jingping Zhao,  Guidelines Disconcordance in Acute Bipolar Depression: Data from the National Bipolar Mania Pathway Survey (BIPAS) in Mainland China  PLoS ONE  2014  9(4):- 
    Zuowei Wang, Chen Zhang, Jia Huang, Chengmei Yuan, Wu Hong, Jun Chen, Shunying Yu, Lin Xu, Keming Gao,  MiRNA-206 and BDNF genes interacted in bipolar I disorder  Journal of Affective Disorders  2014  162():116-119 
    Zuowei Wang, Zezhi Li, Keming Gao,  Association between brain-derived neurotrophic factor genetic polymorphism Val66Met and susceptibility to bipolar disorder: a meta-analysis  BMC Psychiatry (Impact Factor: 2.24). 12/2014; 14(1):5.   2014  14(1):5- 
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    Chen Zhang, Zhiguo Wu, Wu Hong, Zuowei Wang, Daihui Peng, Jun Chen, Chengmei Yuan, Shunying Yu, Lin Xu,  Influence of BCL2 gene in major depression susceptibility and antidepressant treatment outcome  J Affect Disord  2014  155():288-294 
    Zezhi Li, Chen Zhang, Jinbo Fan, Chengmei Yuan, Jia Huang, Jun Chen, Zhenghui Yi, Zuowei Wang, Wu Hong, Yong Wang, Weihong Lu, Yangtai Guan, Zhiguo Wu, Yousong Su, Lan Cao, Yingyan Hu, Yong Hao, Mingyuan Liu, Shunying Yu, Donghong Cui, Lin Xu, Yanyan Song,  Brain-derived neurotrophic factor levels and bipolar disorder in patients in their first depressive episode: 3-year prospective longitudinal study  Br J Psychiatry  2014  205(1):29-35 
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    Zhiguo Wu, Jun Chen, Chengmei Yuan, Wu Hong, Daihui Peng, Chen Zhang, Lan Cao,  Difference in remission in a Chinese population with anxious versus nonanxious treatment-resistant depression: A report of OPERATION study  J Affect Disord  2013  150(3):834-839 
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    Jun Cai, Wen Zhang, Zhenghui Yi, Weihong Lu, Zhiguo Wu, Jun Chen, Shunying Yu,, Chen Zhang  Influence of polymorphisms in genes SLC1A1, GRIN2B, and GRIK2 on clozapine-induced obsessive-compulsive symptoms  Psychopharmacology (Berl)  2013  230(1):49-55 
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    Zhang C, Li Z, Shao Y, Xie B, Du Y,, Yu S  Association study of tryptophan hydroxylase-2 Gene in schizophrenia and its clinical features in Chinese han population  J Mol Neurosci  2011  43(3):406-11 
    Chen J, Muzina DJ, Kemp DE, Conroy C, Chan P, Serrano MB, Ganocy SJ,, Calabrese JR, Gao K  Safety and efficacy of olanzapine monotherapy in treatment-resistant bipolar mania: a 12-week open-label study  Human Psychopharmacology Clinical and Experimental  2011  26(8):588-95 
    Peng DH, Jiang KD,, Xu YF, Shen T, Long XY, Liu J, Zang YF  Decreased regional homogeneity in major depression as revealed by resting-state functional magnetic resonance imaging  Chinese Medical Journal  2011  124(3):369-373 
    Wang Z, Kemp DE, Chan PK, Fang Y ,, Calabrese JR, Gao K  Comparisons of the Tolerability and Sensitivity of Quetiapine-XR in the Acute Treatment of Schizophrenia, Bipolar Mania, Bipolar Depression, Major Depressive Disorder, and Generalized Anxiety Disorder  The International Journal of Neuropsychopharmacology  2011  14(1):131-142. 
    Wang Z, Gao K, Kemp DE, Chan PK, Serrano MB, Conroy C,, Ganocy SJ, Findling RL, Calabrese JR   Lamotrigine Adjunctive Therapy to Lithium and Divalproex in Depressed Patients with Rapid Cycling Bipolar Disorder and a Recent Substance Use Disorder: A 12-week, Double-Blind, Placebo-Controlled Pilot Study  Psychopharmacol Bull  2010  43(4):5-21 
    Zhang C, Xie B, Du Y, Cheng W,, Yu S  Further evidence that methylenetetrahydrofolate reductase A1298C polymorphism is a risk factor for schizophrenia  J Neural Transm  2010  117:1115-1117 
    Chen J,, Kemp DE, Calabrese JR, Gao K  Switching to hypomania and mania: differential neurochemical, neuropsychological, and pharmacologic triggers and their mechanisms  Curr Psychiatry Rep  2010  12:512-521 
    , Yuan C, Xu Y, Chen J, Wu Z, Cao L, Yi Z, Hong W, Wang Y, Jiang K, Gao K, Cui X, Nierenberg AA; OPERATION Study Team  Comparisons of the Efficacy and Tolerability of Venlafaxine-XR, Mirtazepine, and Paroxetine in Treatment-Resistant Depression: a Double-blind, Randomized Pilot Study in a Chinese Population  Journal of Clinical Psychopharmacology  2010  30(4):357-364