• 基本信息
    导师姓名: 李晓波 学科代码: 100201
    性别: 学科名称: 内科学
    培养单位: 附属仁济医院 三级学科 消化系病
    导师类型: 硕士生导师 专业领域名称: 内科学 专业学位
    联系方式: lxb_1969@163.com 专业领域代码: 105101
    邮编: 邮箱地址: lxb_1969@163.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    上海消化内镜学会小肠病学组组长
    上海消化内镜学会委员兼秘书
    亚太NBI培训组织(ANBIG)成员
    中国抗癌协会内镜学组委员
    全国消化内镜学会早癌协作组和胃协作组委员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    2019SY003PD-L2分子标志物结合激光共聚焦显微内镜用于结直肠肿瘤诊断的应用推广上海市卫生健康委先进适宜技术推广项目 2019-07~2022-06 60万元  课题负责人
    16ZR1420400LRG1在低氧诱导结肠癌细胞上皮-间质转化中的作用机制上海市科学技术委员会自然基金项目 2016-07~2019-06 20万元  课题负责人
    16441906903内镜下超声穿刺针在间质瘤诊疗中的应用研究上海市科学技术委员会基金项目 2016-07~2019-06 20万元  课题负责人
    PYMDT-001胃癌窄带成像内镜早期诊断模型建立及多学科协作治疗模式研究上海仁济医院临床科研创新培育基金 2016-06~2019-06 30万元  课题负责人
     含雷贝拉唑的四联疗法和高剂量二联疗法补救治疗Hp感染的作用横向课题 2012-06~2013-12 5万元  课题负责人
     替普瑞酮(施维舒)联合雷贝拉唑预防胃ESD术后出血的疗效比较横向课题 2012-03~2014-03 3万元  课题负责人
    12YZ036结直肠平坦、凹陷型早期癌内镜诊治及分子机制研究上海市教委 2012-01~2014-12 8万元  课题负责人
    09DZ1950102基于内镜的胃癌早期诊断与微创治疗研究上海市科委 2009-07~2012-07 10万元  课题参与人
    2007107急性胃肠道感染后功能性消化不良的临床特点及症状产生机制研究上海市卫生局,局级课题 2008-01~2009-12 3万元  课题负责人
    06HX21007雷贝拉唑按需治疗非糜烂性胃食管反流病的有效性和安全性研究横向课题 2006-03~2008-03 5万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Zhou YJ, Zhu GQ, Zhang QW, Zheng KI, Chen JN, Zhang XT, Wang QW,  Survival-Associated Alternative Messenger RNA Splicing Signatures in Pancreatic Ductal Adenocarcinoma: A Study Based on RNA-Sequencing Data.  DNA Cell Biol  2019  38(11):1207-1222 
    Zhang QW, Zhang XT, Tang CT, Lin XL, Ge ZZ,  EGFL6 promotes cell proliferation in colorectal cancer via regulation of the WNT/β-catenin pathway.  Mol Carcinog  2019  58(6):967-979 
    Zhang XT1, Zhang QW1, Liu F2, Lin XL3, Chen JN1,  Endoscopic features of sessile serrated adenoma/polyps under narrowband imaging: A retrospective study  J Dig Dis  2019  20(3):135-142 
    Wu S1, Chen JN1, Zhang QW1, Tang CT1, Zhang XT1, Tang MY1,, Ge ZZ3.   A New Metastatic Lymph Node Classification-based Survival Predicting Model in Patients With Small Bowel Adenocarcinoma: A Derivation and Validation Study.  EBioMedicine  2018  32:134-141 
    Zhang QW, Teng M, Tang CY, Yan XL, Ge ZZ,  Caution with iceberg model for colonoscopy in mind! A large easily missed sessile serrated polyp surrounding seemingly diminutive protruded polyp: A case report  J Dig Dis  2018  19(6):377-380 
    Zhang QW, Teng LM, Zhang XT, Zhang JJ, Zhou Y, Zhou ZR, Hou YC, Ge ZZ,  Narrow-band imaging in the diagnosis of deep submucosal colorectal cancers: a systematic review and meta-analysis.  Endoscopy  2017  49(6):564-580. 
    Qing-Wei Zhang, Ying Zhou, Jing-Jing Zhang , Hai-Yan Li , Jie-Ying Song , Zhi-Zheng Ge,  Role of targeted biopsy under magnifying endoscopy with narrow band imaging may be not necessary: a prospective diagnostic accuracy study  European Journal of Gastroenterology & Hepatology  2017  29(4):414-422 
    Zhang QW, Lin XL, Zhang CH, Tang CY, Zhang XT, Teng LM, Ge ZZ,  The influence of marital status on the survival of patients with esophageal cancer: a population-based, propensity-matched study  Oncotarget  2017  22;8(37):62261-62273 
    Zhang JJ, Zhu LY, Fang JY, Ge ZZ,  LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1α activation.  J Exp Clin Cancer Res.  2016  9;35:29. 
    Zhu Linyin,, Chen Yingxuan, Fang Jingyuan, Ge Zhizheng.  High-mobility group Box-1: A novel inducer of the epithelial-mesenchymal transition in colorectal carcinoma  Cancer Lett  2015  57(2):527-534 
    Zhou Y,  Endoscopic prediction of tumor margin and invasive depth in early gastric cancer  J Dig Dis   2015  16(6):303-10 
    Zhou Y,  Endoscopic prediction of tumor margin and invasive depth in early gastric cancer.   J Dig Dis.   2015  16(6):303-310. 
    Zhu LY,Ren L,Chen YX,Fang JY,Ge ZZ,  Redox status of high-mobility group box 1 performs a dual role in angiogenesis of colorectal carcinoma  J Cell Mol Med  2015  19(9):2128-35 
    Zhang JJ, Gu LY, Chen XY, Gao YJ, Ge ZZ,  Endoscopic diagnosis of invasion depth for early colorectal carcinomas: a prospective comparative study of narrow-band imaging, acetic acid, and crystal violet.   Medicine (Baltimore)  2015  94(7):e528  
    Zhang JJ, Gu LY, Chen XY, Gao YJ, Ge ZZ,  Endoscopic diagnosis of invasion depth for early colorectal carcinomas: a prospective comparative study of narrow-band imaging, acetic acid, and crystal violet  Medicine(Baltimore)  2015  94(7):e528 
    李海燕,  替普瑞酮联合雷贝拉唑预防胃ESD术后出血的疗效研究  胃肠病学  2015  20(9):546-549 
    Zhu LY,Ren L,,Ge ZZ  Observation of Microvessels and Invasion in Early Colorectal Neoplasms by Narrow Band Imaging: Combination with CD34 and Matrix Metalloproteinase-7 Expression  Eur J Gastroenterol Hepatol  2014  26(12):1428-1433 
    张晶晶,戈之铮,  带成像内镜下NICE分型对结直肠肿瘤的诊断价值  中华消化内镜杂志  2014  31(11):8-12 
    Ren L,Lu H,Li HY,Zhu LY,Xu XQ,Gu LY,Ge ZZ,  New dual therapy for primary treatment of Helicobacter pylori infection: A prospective randomized study in Shanghai, China  J Dig Dis   2014  15(11); 622–627 
    宋洁莹,朱凌音,  经内镜切除或手术治疗后早期结直肠癌的病理分析和疗效评价  胃肠病学  2014  19(8):476-481 
    钱斌,李海燕,薛寒冰,赵韫嘉,戴军,陈晓宇,高云杰,戈之铮,  早期胃癌内镜治愈性切除的影响因素   中华消化内镜杂志  2014  31(7):389-392 
    康海锋,李海燕,朱凌音,  结肠进展期腺瘤的内镜下检出特点  中华消化内镜杂志  2014  31(9):542-544 
    宋洁莹,李海燕,朱凌音,陈晓宇,戈之铮,  放大内镜结合窄带成像技术指导活检对诊断早期胃癌的重要性  中华消化内镜杂志  2014  31(8):455-458 
    康海峰,李海燕,朱凌音,张晶晶,  含进展组织腺瘤在结直肠微小息肉中的检出率  胃肠病学  2014  19(7):389-393 
    Zhu LY,  Narrow band imaging: application for early-stage gastrointestinal neoplasia.  J Dig Dis.  2014  15(5):217-223 
    任玲,顾立阳,李海燕,宋燕,  伊托必利在改善便秘患者结肠镜前肠道准备中的作用  中华消化杂志  2013  33(2):93-96 
    Zhu LY,Dai J,Zhao YJ,Xue HB,Ge ZZ,  Endoscopic resection for gastric epithelial neoplasia: how to solve pathological discrepancy and achieve curative resection?  J Dig Dis.   2013  14(5):231-237 
    Li Hai-Yan, Dai Jun, Xue Han-Bing, Zhao Yun-Jia, Chen Xiao-Yu, Gao Yun-Jie, Song Yan, Ge Zhi-Zheng,  Application of magnifying endoscopy with narrow-band imaging in diagnosing gastric lesions: a prospective study.   Gastrointestinal Endoscopy  2012  76(6):1124-32 
    林炜炜,顾立扬,任玲,宋燕,戈之铮,  低剂量聚乙二醇联合硫酸镁用于肠道准备的效果评价   胃肠病学  2012  17(1):10-13 
    Li-Yang Gu, Wei-Wei Lin, Hong Lu, Xiao-Yu Chen, Zhi-Zheng Ge,  Quadruple Therapy with Medications Containing Either Rufloxacin or Furazolidone as a Rescue regimen in the Treatment of Helicobacter pylori-Infected Dyspepsia Patients: A Randomized Pilot Study.  Helicobacter  2011  16(4):284-288 
    , Huimin Chen, Yunjie Gao, Xiaoyu Chen, Zhizheng Ge  Prediction of histology and invasive depth of colorectal neoplasia based on morphology of surface depression using magnifying chromocolonoscopy  Int J Colerec Dis  2010  25(1):79-85 
    , Huimin Chen, Hong Lu, Weiguang Li, Xiaoyu Chen, Yansheng Peng, Zhizheng Ge  The study on the Role of Inflammatory Cells and Mediators in Post Infectious Functional Dyspepsia  Scand J Gastroenterol  2010  45(5):573-581 
    , 陈慧敏, 高云杰, 沈镭, 薛寒冰, 赵韫嘉, 陈晓宇, 戈之铮  放大色素内镜在结直肠肿瘤内镜黏膜切除治疗中的应用  中华消化杂志  2010  30(1):7-10 
    陈慧敏,, 姜智敏, 赵韫嘉, 戈之铮  伊托必利治疗功能性消化不良重叠便秘型肠易激综合征疗效观察  中华消化杂志  2010  30(2):102-105 
    , 陈慧敏, 戴军, 高云杰, 戈之铮.  胶囊内镜指导双气囊内镜进镜方式的临床研究  中华消化内镜杂志  2010  27(8):396-398 
    陈慧敏,, 戈之铮  雷贝拉唑和铝碳酸镁治疗胆囊切除术后伴胆汁反流的胃炎作用比较  中华消化杂志  2010  30(8):529-534 
    , 戴军, 陈慧敏, 庄捷, 宋燕, 高云杰, 戈之铮.  对双气囊内镜检查深度全新评估方法的初步研究  中华消化内镜杂志  2010  27(12):625-628 
    , 宋燕, 戴军, 高云杰, 戈之铮  螺旋管式小肠镜临床应用价值初探  中华消化内镜杂志  2010  27(1):9-11 
    , Dai J, Chen HM, Zhuang J, Song Y, Gao YJ, Ge ZZ.  A novel modality on estimation of the enteroscopic insertion depth at double-balloon enteroscopy.   Gastrointestinal Endoscopy  2010  72(5):999-1005 
    Huimin Chen,, Zhizheng Ge,Yunjie Gao, Xiaoyu Chen, Yun Cui  Rabeprazole combined with hydrotalcite is effective for patients with bile reflux gastritis after cholecystectomy  Can J Gastroenterol  2010  24(3):197-201 
    , 陈慧敏, 高云杰, 陈晓宇, 戈之铮  结直肠肿瘤表面凹陷形态对判断病变性质及浸润深度的作用  中华消化内镜杂志  2010  27(2):69-73 
    , Dai J, Lu H, Gao Y, Chen H, Ge Z  A prospective study on evaluating the diagnostic yield of video capsule endoscopy followed by directed double-balloon enteroscopy in patients with obscure gastrointestinal bleeding  Dig Dis Sci  2010  55(6):1704-10 
    , Hui Min CHEN, Hong LU, Qing ZHENG, Xiao Yu CHEN, Yan Shen PENG, Zhi Zheng GE, Wen Zhong LIU  Role of Helicobacter pylori infection on neuronal expression in the stomach and spinal cord of a murine model  J Dig Dis  2009  10(4):286-292 
    , Chen H, Dai J, Gao Y, Ge Z  Predictive role of capsule endoscopy on the selection of the insertion route of a following double-balloon enteroscopy  Endoscopy  2009  41(9):762-766 
    Huimin Chen,, Zhizheng Ge  Comparative study on two colonic bowel preparations for patients with chronic constipation  Scand J Gastroenterol  2009  44(3):375-379 
    , Hong LU, XiaoYu, CHEN, ZhiZheng GE  Comparative study on two colonic bowel preparations for patients with chronic constipation  J Dig Dis  2008  9(4):208-212 
    , Ge ZZ, Chen XY, Liu WZ  Duodenal gastric metaplasia and Helicobacter pylori infection in patients with diffuse nodular duodenitis  Bra J Med Bio Res  2007  40(7):897-902