• 基本信息
    导师姓名: 吴镜湘 学科代码: 100217
    性别: 学科名称: 麻醉学
    培养单位: 附属胸科医院 三级学科
    导师类型: 博士生导师 专业领域名称: 麻醉学 专业学位
    联系方式: 18930857186 专业领域代码: 105118
    邮编: 200030 邮箱地址: wjx1132@163.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    中国心胸血管麻醉学会胸科麻醉分会副主任委员
    麻醉科主任
    上海市医学会麻醉学专科分会委员
    上海市医师协会麻醉科医师分会委员
    上海市医学会麻醉学专科分会心胸学组副组长
    上海市中西医结合学会疼痛与麻醉专委会常委
    上海市麻醉质控中心委员
    《上海医学》杂志第五届编委会通信编委
    中国中西医结合学会麻醉专业委员会常委
    上海市心胸麻醉专科医师培训基地主任
    中华医学会麻醉学分会教育与人才培养学组委员
    中国心胸血管麻醉学会围术期康复分会常委
    上海市中西医结合学会麻醉与镇痛学组青年委员
    中国抗癌协会肿瘤麻醉与镇痛专业委员会委员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    YG2024LC10无创心脑血流动力学监护仪的研发及转化研究上海交通大学医工交叉重点项目(转化项目) 2024-01~2026-12 200万元  课题负责人
    RCLX2315002基于卷积神经网络的胸外科手术肺隔离气道评估和管理研究国家卫健委人才交流服务中心 2023-02~2024-12 5万元  课题负责人
    BYH20220112心胸麻醉专科医师培训课程上海交通大学医学院毕业后医学教育课程建设项目 2022-11~2023-11 2万元  课题负责人
    HXKT202006注射用甲苯磺酸瑞马唑仑对比丙泊酚用于食管内镜粘膜下剥离术麻醉镇静时血流动力学稳定性的前瞻性随机对照研究上海交通大学医学院教育发展基金会 2021-11~2022-12 10万元  课题负责人
    82071233 破骨细胞分泌Netrin-1促进骨感觉神经突起生长参与骨癌痛的机制研究国家自然科学基金委员会 2021-01~2023-12 55万元  课题负责人
    SHDC2020CR4063中老年患者肺癌切除术中个体化保护性通气策略减少术后肺 部并发症的前瞻性随机对照研究上海申康医院发展中心“三年行动计划”临床研究重点计划 2020-10~2022-09 50万元  课题负责人
    201840319非气管插管保留自主呼吸全身麻醉用于胸腔镜肺部切除手术的前瞻性随机对照研究上海市卫生局课题 2019-01~2021-12 10万元  课题负责人
    81671078骨形态发生蛋白信号系统在骨癌痛大鼠外周痛觉敏化机制中的作用国家自然科学基金委员会 2017-01~2020-12 52万元  课题负责人
    16411967600围术期体温保护策略降低中老年胸科手术患者心肌损伤相关不良事件的研究上海市科学技术委员会(西医引导类项目) 2016-06~2019-06 20万元  课题负责人
    12ZR1428700溶血磷脂酸对脊髓背根神经节P2X3受体介导的大鼠骨癌痛的作用及分子机制上海市自然科学基金面上项目 2012-07~2015-06 10万元  课题负责人
    10501050人才计划基金上海市胸科医院 2012-05~2014-09 10万元  课题负责人
    2007Y28肺移植缺血再灌注损伤内皮功能紊乱机制研究(结题)上海市卫生局 2008-01~2010-03 2万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    He Z, Du J, Wang Q, Chen G, Li X, Zhang Z, Wang S, Jing W, Miao Q, Li Y, Miao Y,  Dye-augmented bandgap engineering of a degradable cascade nanoreactor for tumor immune microenvironment-enhanced dynamic phototherapy of breast cancer.  Acta biomaterialia  2024  DOI: 10.1016/j.actbio.2024.01.007 (Q1/IF=9.7,中科院一区) 
    Tong C, Niu Z, Zhu H, Li T, Xu Y, Yan Y, Miao Q, Jin R, Zheng J, Li H,  Development and external validation of a novel model for predicting new clinically important atrial fibrillation after thoracoscopic anatomical lung cancer surgery A multi-center retrospective cohort study.   International Journal of Surgery (London, England).   2024  DOI: 10.1097/JS9.0000000000001006(Q1/IF=15.3,中科院一区) 
    Chen G, Gu L, Liu Y, Du J, Qi Q, Miao Q,, Miao Y, Li Y:   Topology-regulated nanocatalysts for ferroptosis-mediated cancer phototherapy.   Journal of colloid and interface science   2024  656: 320-331 (Q1/ IF=9.9,中科院一区) 
    Tong C, Shen Y, Zhu H, Zheng J, Xu Y,  Continuous Relationship of Operative Duration with Risk of Adverse Perioperative Outcomes and Early Discharge Undergoing Thoracoscopic Lung Cancer Surgery.   Cancers (Basel)   2023  15,371:1-14 (Q2/IF=5.2) 
    Zhang Y, Wang W, Gong Z, Peng Y, Li X, Zhang Z, Zhang X, You X,  Activation of the STING pathway induces peripheral sensitization via neuroinflammation in a rat model of bone cancer pain  Inflamm Res   2023  72: 117-132 (Q2/IF=6.7) 
    Tong C, Miao Q, Zheng J,  A novel nomogram for predicting the decision to delayed extubation after thoracoscopic lung cancer surgery.   Ann Med   2023  55: 800-807 (Q2/IF=4.4) 
    Tong C, Zheng J,  The effects of paravertebral blockade usage on pulmonary complications, atrial fibrillation and length of hospital stay following thoracoscopic lung cancer surgery.   Journal of Clinical Anesthesia  2022  79:110770. (Q1/IF=6.7)  
    Huang C, Huang Q, Shen Y, Liu K,  General Anaesthesia with Double-lumen intubation compared to an Opioid-sparing Strategies with laryngeal mask for Thoracoscopic Surgery: A Randomised Trial.  Anaesthesia, critical care & pain medicine   2022  41: 101083 (Q1/IF=5.5) 
    Sessler DI, Pei L, Li K, Cui S, Chan MTV, Huang Y,, He X, Bajracharya GR, Rivas E, Lam CKM, Investigators P  Aggressive intraoperative warming versus routine thermal management during non-cardiac surgery (PROTECT): a multicentre, parallel group, superiority trial.  Lancet   2022  399: 1799-1808(Q1/IF=168.9中科院一区) 
    Qiu Y, Gu W, Zhao M, Zhang Y,  The hemodynamic stability of remimazolam compared with propofol in patients undergoing endoscopic submucosal dissection: A randomized trial.  Front Med (Lausanne)  2022  9:938940. (Q2/IF=3.9) 
    Qiu Y, Lu X, Liu Y, Chen X,  Efficacy of the intraoperative opioid-sparing anesthesia on quality of patients' recovery in video-assisted thoracoscopic surgery: a randomized trial  J Thorac Dis  2022  14: 2544-2555 
    Li Q, Zhao M, Wu D, Guo X,  Adverse outcomes of artificial pneumothorax under right bronchial occlusion for patients with thoracoscopic-assisted oesophagectomy in the prone position versus the semiprone position.   Front Oncol  2022  12:919910. 
    Tong C, Li T, Shen Y, Zhu H, Zheng J,  Obesity Does Not Increase Perioperative Outcomes in Older Patients Undergoing Thoracoscopic Anatomic Lung Cancer Surgery.   Front Oncol   2022  12: 881467 
    Tong C, Lu H, Zhu H,  Impact of body mass index on perioperative and oncological outcomes in elderly patients undergoing minimally invasive McKeown esophagectomy for esophageal squamous cell carcinoma  Cancer Med  2022  11: 2913-2922 
    Tong C, Liu Y,  Development and validation of a novel nomogram for postoperative pulmonary complications following minimally invasive esophageal cancer surgery.  Updates Surg  2022  74: 1375-1382 
    吴玉兰,孙灵,  术前麻醉评估中心在胸科手术中的效果评价  国际麻醉学与复苏杂志  2022  43(4):345-348. 
    , Li X, Zhang X, Wang W, You X.   What role of the cGAS-STING pathway plays in chronic pain?   Front Mol Neurosci  2022  15:963206.  
    Tang W, Qiu Y, Lu H, Xu M,  Stroke Volume Variation-Guided Goal-Directed Fluid Therapy Did Not Significantly Reduce the Incidence of Early Postoperative Complications in Elderly Patients Undergoing Minimally Invasive Esophagectomy: A Randomized Controlled Trial  Front Surg  2021  8:794272. 
    Tong C, Cao H, Xu Y, Li D, Zhang H, Xu M, Luo Y,  Causes, Risk Factors and Outcomes of Patients Readmitted to the Intensive Care Unit After Esophageal Cancer Surgery: A Retrospective Cohort Study.   World J Surg   2021  45:2167-75. 
    Qiu Y,, Huang Q, Lu Y, Xu M, Mascha EJ, Yang D, Ince I, Sessler DI  Acute pain after serratus anterior plane or thoracic paravertebral blocks for video-assisted thoracoscopic surgery: A noninferiority randomised trial.  Eur J Anaesthesiol   2021  38:S97-S105. 
    Miao Q, Wu DJ, Chen X, Xu M, Sun L, Guo Z, He B,  Target blood pressure management during cardiopulmonary bypass improves lactate levels after cardiac surgery: a randomized controlled trial  BMC Anesthesiol  2021  21(1):309. 
    Li Q, Yao H, Xu M,  Dexmedetomidine combined with sufentanil and dezocine-based patient-controlled intravenous analgesia increases female patients' global satisfaction degree after thoracoscopic surgery  Journal of cardiothoracic surgery  2021  16(1):102 
    Gu W, Tang W, Zhang Z, Xu M,  Two different troponin isoforms for detecting early myocardial injury after curative resection of oesophageal cancer  J Cardiothorac Surg  2020  15(1):189.  
    , 徐美英  胸外科快通道麻醉  上海医学   2020  43(02):67-71 
    Huang C, Yao H, Huang Q, Lu H, Xu M,  A novel nomogram to predict the risk of anastomotic leakage in patients after oesophagectomy.   BMC surgery  2020  20(1):64.  
    刘坤, 徐美英, 黄成娅, 童朝阳,  老年患者肺切除术后个体化通气对苏醒期呼吸力学及氧合的影响.  国际麻醉学与复苏杂志  2020  41(4):344-349.  
    Qiu Y, Huang C, Zhang Z, Feinstein M, Xu M,  Incidence and risk factors of vocal cord injuries after intubation of double-lumen endobronchial tubes under UEScopes: A prospective   J Clin Anesth  2020  60:62-63.  
    Xie S, Yu Q, Li T, Xu M,, Li Y  Comparison of the effect of different degrees of passive leg raising on the internal jugular vein cross-sectional area in patients before thoracic surgery  BMC anesthesiology  2019  2019, 19(1):78 
    Gu W, Xu M, Lu H, Huang Q,  Nebulized dexmedetomidine-lidocaine inhalation as a premedication for flexible bronchoscopy: a randomized trial.   Journal of thoracic disease  2019  11(11):4663-4670.  
    Zhang Z, Xu M, Wu D, Zhang X,  Postoperative Myocardial Injury in Middle-Aged and Elderly Patients Following Curative Resection of Esophageal Cancer With Aggressive or Standard Body Temperature Management: A Randomized Controlled Trial.  Anesthesia and analgesia  2019  129 (2) : 352-359 
    黄成娅, 胡英杰, 刘坤, 童朝阳,, 徐美英  全身麻醉诱导和苏醒期患者脑皮质区激活或抑制的差异性分析:功能近红外光谱法.   中华麻醉学杂志   2019  39(11):1348-1351.  
    Liu K, Huang C, Xu M,, Frerichs I, Moeller K, Zhao Z:   PEEP guided by electrical impedance tomography during one-lung ventilation in elderly patients undergoing thoracoscopic surgery  Annals of translational medicine   2019  7(23):757.  
    Li Q, Zhang X, Xu M,  A retrospective analysis of 62,571 cases of perioperative adverse events in thoracic surgery at a tertiary care teaching hospital in a developing country  Journal of cardiothoracic surgery  2019  14(1):98 
    Wang W, Jiang Q,, Tang W, Xu M  Upregulation of bone morphogenetic protein 2 ( Bmp2) in dorsal root ganglion in a rat model of bone cancer pain.  Mol Pain  2019  15(1):1-10 
    顾韡, 章祺, 徐美英,  连续无创动脉血压监测在气管镜诊疗麻醉中的应用  国际麻醉学与复苏杂志  2019  40(3):208-212 
    徐江宁, 张晓峰, 徐美英,  硬膜外阻滞对全麻下肺癌根治术患者术后远期生活质量的影响  中华麻醉学杂志  2018  38(7):833-836 
    Zhao Z, Wang W, Zhang Z, Xu M, Frerichs I,, Moeller K  Influence of tidal volume and positive end-expiratory pressure on ventilation distribution and oxygenation during one-lung ventilation.   Physiological measurement  2018  39(3):034003. 
    Wang W, Xu MY,, Zhao ZQ  Influence of tidal volume on ventilation distribution and oxygenation during one-lung ventilation  The Kaohsiung journal of medical sciences.  2018  34(7):420-421 
    , 王委, 张作晶, 徐美英  胸腔镜手术患者单肺通气时非通气侧肺通气方式及通气量影响因素:肺阻抗断层成像术监测  中华麻醉学杂志  2017  37(3):348-351 
    王委, 徐美英,  不同剂量复方雪莲胶囊对大鼠骨癌痛的影响  中华麻醉学杂志  2016  36(4):467-470. 
    , Yuan XM, Wang Q, Wei W, Xu MY  Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats  Mol Pain  2016  12:1-10 
    Chen X,, You XJ, Zhu HW, Wei JL, Xu MY.  Cold ischemia-induced autophagy in rat lung tissue.   Molecular medicine reports  2015  11:2513-9 
    Yuan XM,, Wang Q, Xu MY,  The antinociceptive effect of systemic administration of low dose tramadol and dexmedetomidine combination on a rat model of bone cancer pain.   European Journal of Anesthesia.   2014  31: 30-34 
    ,邱郁薇,朱宏伟,徐美英  不同气管插管方式在食管癌微创手术中通气效果比较  中华胸部外科电子杂志  2014  1:53-56 
    , Zhu HW, Chen X, Wei JL, Zhang XF, Xu MY  Inducible nitric oxide synthase inhibition reverses pulmonary arterial dysfunction in lung transplantation  Inflamm Res.  2014  63:609-18 
    , Wei J, You X, Chen X, Zhu H, Zhu X, Liu Y, Xu M  Inhibition of hydrogen sulfide generation contributes to lung injury after experimental orthotopic lung transplantation  J Surg Res  2013  182(1):e25-33 
    ,鲁云纲,朱宏伟,邱郁薇,徐美英  曲马多对肺癌患者开胸手术围术期免疫功能的 影响  临床麻醉学杂志  2012  28(8):752-753 
    , Xu MY, Miao XR, Lu ZJ, Yuan XM, Li XQ, Yu WF  Functional up-regulation of P2X3 receptors in dorsal root ganglion in a rat model of bone cancer pain  European Journal of Pain  2012  16(11):1378–1388 
    ,朱宏伟,徐美英  诱生型一氧化氮合酶再肺移植大鼠肺血管功能改变中的作用  上海医学  2011  34(4):264-270 
    ,吴东进,沈耀峰,徐美英  心肺转流中丙泊酚对鱼精蛋白中和肝素后肺高压的影响  临床麻醉学杂志  2011  27(8):769-711 
    ,沈耀峰,陈旭,章琪,徐美英  近红外光谱联合脑电双频谱指数监测在深低温停循环手术脑氧平衡监测中的应用  上海交通大学学报( 医学版)  2011  31(3):317-321 
    ,徐美英,缪雪蓉,李晓青,俞卫锋  骨癌痛模型大鼠脊髓背根神经节P2X3受体的表达变化  第二军医大学学报  2009  30(3):244-248