• 基本信息
    导师姓名： 赵强 学科代码： 100210
    性别： 男 学科名称： 外科学
    培养单位： 附属瑞金医院 三级学科 胸心外
    导师类型： 博士生导师 专业领域名称： 外科学 专业学位
    联系方式： 上海市瑞金二路197号 瑞金医院心脏外科 Email：zq11607@rjh.com.cn 手机：13701695256 专业领域代码： 105111
    邮编： 200025 邮箱地址： zq11607@rjh.com.cn
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    美国胸心外科学会（AATS），委员
    美国心外科医师协会（STS），会员
    中华医学会胸心血管外科分会，常委
    中国医师协会心血管外科分会，常委，冠心病主委，心衰外科副主委
    中国医师协会机器人外科分会，常委
    上海医学会心血管外科分会，主委
    上海医师协会心血管外科分会，首届会长
    亚太区心脏瓣膜协会，常委
    国际微创心脏外科协会（ISMICS），委员
    上海市政协委员
    农工民主党上海交通大学医学院委员，副主委
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    NCT04310995ASRAB-Pilot临床研究瑞金医院 2020-06~2021-06 100万元  课题负责人
    NCT03977129FAVOR IV-QVAS多中心临床研究瑞金医院 2019-08~2023-08 260万元  课题负责人
    DLY201802冠状动脉旁路移植术不同抗血小板治疗策略的多中心随机对照研究之长期预后随访（DACAB-FE）交大医学院 2019-04~2021-04 50万元  课题负责人
    19441906800晚期心力衰竭患者新型心肌填充物及配套注射器械的开发上海市科委 2019-04~2022-03 80万元  课题负责人
    18411966200肥厚型梗阻性心肌病超声引导下经皮室间隔内射频消融治疗的方法研究上海市科委 2018-09~2021-09 80万元  课题负责人
    81671832MYDGF介导的微环境影响心梗后hPSC-CMs移植的机制研究自然科学基金 2017-01~2020-12 58万元  课题负责人
    NCT 01561651LAAO III研究横向国际多中心（PHRI），加拿大卫生部 2016-02~2019-10 80万元  子课题负责人
    81571826可降解3D微支架积木引导hPSC-CMs的兴奋收缩藕联及对左室功能的研究国家自然基金委 2015-08~2019-08 65万元  课题负责人
    NCT01991795THEMIS研究横向国际多中心（AZ） 2015-03~2017-06 120万元  子课题负责人
    NCT 01926438COMPASS研究横向国际多中心（拜耳） 2015-03~2020-06 50万元  子课题负责人
    NCT02201771冠状动脉旁路移植术后不同抗血小板治疗策略的疗效比较（DACAB）横向，国际多中心 2014-10~2016-10 450万元  课题负责人
    NCT02201771DACAB多中心临床研究瑞金医院 2014-08~2018-08 450万元  课题负责人
    SHDC12013118Heartware植入性心室辅助装置治疗晚期心力衰竭多中心临床研究申康医院发展中心新兴前沿技术 2014-01~2016-12 80万元  课题参与人
    81170126经SDF-1α修饰的脱细胞心脏支架内重建血管网促进构建组织工程心肌的基础研究国家自然基金委 2012-01~2012-12 14万元  课题负责人
    11JC1408000MiR-17-92微小RNA基因簇对心肌缺血损伤的保护作用和机制研究上海市科委 2012-01~2014-12 30万元  课题负责人
    81170126经SDF-1 修饰的脱胸部心脏支架内重建血管网促进构建组织工程心肌的基础研究自然科学基金 2011-05~2012-12 14万元  课题负责人
    10XD1402900缺氧预处理改善心脏干细胞归巢和活力的作用及机理研究上海上海市优秀学科带头人 2010-04~2012-03 40万元  课题负责人
    YG2009ZD101增强现实导航技术对心脏介入植入物的示踪定位作用上海交通大学Med－X重点项目 2009-07~2011-08 40万元  课题负责人
    Site173CORONARY加拿大国际合作 2008-05~2012-04 200万元  课题负责人
     导航技术在机器人辅助心脏手术中的应用上海市重点人才基金 2008-05~2010-04 10万元  课题负责人
    2006AA02Z301导航技术在机器人辅助心脏手术中的应用863课题 2006-05~2009-04 80万元  课题负责人
    30470481/C010515复合天然交联剂对动物心脏瓣膜交联作用的研究自然科学基金 2005-05~2007-04 20万元  课题负责人
    2006BAI01A09提高急危重心血管疾病外科疗效的临床研究十一五子课题 2005-05~2008-04 30万元  子课题负责人
     中国冠心病外科治疗登记研究阜外心血管病医院 2005-05~2011-04 15万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Chenyu Jiang, Luzhi Zhang, Qi Yang, Shixing Huang, Hongpeng Shi, Qiang Long, Bei Qian, Zenghe Liu, Qingbao Guan, Mingjian Liu, Renhao Yang,  Self-healing polyurethane-elastomer with mechanical tunability for multiple biomedical applications in vivo.  Nature Communications  2021  12:4395 
    Zhu P, Qiu J, Xu H, Liu J,  Hybrid coronary revascularization versus total arterial revascularization for the treatment of left main coronary artery disease.  Ann Transl Med.   2021  9(4):285 
    Shixing Huang, Dong Lei, Qi Yang, Yang Yang, Chenyu Jiang, Hongpeng Shi, Bei Qian, Qiang Long, Wenyi Chen, Youming Chen, Lan Zhu, Wenjie Yang, Lan Wang, Wangxi Hai, Qiang Zhao*, Zhengwei You*, Xiaofeng Ye*  A perfusable multifunctional epicardial device improves cardiac function and tissue repair.   Nature Medicine  2021  27(3):480-490 
    Jiaxi Zhu, Yunpeng Zhu, Minlu Zhang, Qing Xue, Junlong Hu, Hao Liu, Rui Wang, Xiaowei Wang,  Influence of lipoproteins and antiplatelet agents on vein graft patency 1 year after coronary artery bypass grafting  Journal of Thoracic and Cardiovascular Surgery  2020  5 
    Chenyue Tang, Yunpeng Zhu, Xiaobo Yang, Bin Xu, Cong Ye, Yi Yang, Jie Zhong,  Upper gastrointestinal mucosal injury associated with ticagrelor plus aspirin, ticagrelor alone, or aspirin alone at 1-year after coronary artery bypass grafting  Journal of Gastroenterology and Hepatology  2020  4 
    Hongpeng Shi, Tong Xue, Yang Yang, Chenyu Jiang, Shixing Huang, Qi Yang, Dong Lei, Zhengwei You, Tuo Jin, Fei Wu,, Xiaofeng Ye*  Microneedle-mediated gene delivery for the treatment of ischemic myocardial disease  Science Advances  2020  6:1-14. eaaz3621 
    Qi Yang, Dong Lei, Shixing Huang, Yi Yang, Yang Yang, Xiaofeng Ye, Zhengwei You,  Effects of the different-sized external stents on vein graft intimal hyperplasia and inflammation  Ann Transl Med  2020  8(4):102 
    Kangmu Ma, Anqing Chen, Zhe Wang, Jun Liu,  Chordal replacement versus quadrangular resection in degenerative posterior mitral leaflet repair  J Thorac Dis  2019  11(3):827-838 
    Yi Yang a, Yunpeng Zhua, Chenyue Tangb, Qi Yang a, Haoyi Yaoa, Jiapei Qiua, Haiqing Lia, Xiaofeng Yea, Mi Zhou a, Jun Liua, ZheWanga, Anqing Chena and Qiang Zhaoa,  Predictors of early vein graft failure after off-pump coronary artery bypass grafting: angiocomputed tomographic results of 233 patients  European Journal of Cardio-Thoracic Surgery  2019  doi:10.1093/ejcts/ezz207 
    Xiao‐Xi Pan1 | Cheng‐Chao Ruan1 | Xiu‐Ying Liu2 | Ling‐Ran Kong1 | Yu Ma1 | Qi‐Hong Wu1 | Hai‐Qing Li3 | Yan‐Jun Sun3 | An‐Qing Chen3 | Qiang Zhao3 | Fang Wu4 | Xiu‐Jie Wang2 | Ji‐Guang Wang1 | Ding‐Liang Zhu1 | Ping‐Jin Gao1  Perivascular adipose tissue‐derived stromal cells contribute to vascular remodeling during aging  Aging Cell  2019  2019;00:e12969 
    , Yunpeng Zhu, Zhiyun Xu, Cheng ZY, Mei J, Chen X, Wang XW  Effect of ticagrelor plus aspirin, ticagrelor alone, or aspirin alone on saphenous vein graft patency 1 year after CABG  JAMA  2018  319(16):1677-1686 
    Dong Lei, Yang Yang, Zenghe Liu, Shuo Chen, Benyan Song, Ao Shen, Binqian Yang, Sen Li, Zhize Yuan, Quan Qi, Lijie Sun, Yifan Guo, Han Zuo, Shixing Huang, Qi Yang, Xiumei Mo, Chuanglong He, Bo Zhu, Eric M. Jeffries, Feng-Ling Qing, Xiaofeng Ye,  A general strategy of 3D printing thermosets for diverse applications  Materials Horizons  2018  DOI: 10.1039/c8mh00937f 
    Xu YW, Ye XF, Li Z,  Aorta-atria-septum combined incision for aortic valve re-replacement  J Thorac Dis  2018  10(4):E285-E288 
    Zhu P, Ye XF,  Successful surgical treatment of descending aortic interruption: a case report  Heart Sur Forum  2018  16;21(3):E175-E176 
    Zhize Yuan?, Lei Kang?, Zhe Wang, Anqing Chen,, and Haiqing Li  17β-estradiol promotes recovery after myocardial infarction by enhancing homing and angiogenic capacity of bone marrow-derived endothelial progenitor cells through ERα-SDF-1/ CXCR4 crosstalking  Acta Biochim Biophys Sin  2018  2018, 1–10 
    Yunpeng Zhu, Anqing Chen, Zhe Wang, Jun Liu, Junfeng Cai,Mi Zhou and Qiang Zhao*  Ten-year real-life effectiveness of coronary artery bypass using radial artery or great saphenous vein grafts in a single centre Chinese hospital  Interactive CardioVascular and Thoracic Surgery  2017  doi:10.1093/icvts/ivx174 
    Qi Q, Lu L, Li HQ, Yuan ZZ, Chen G, Lin M, Ruan Z, Ye XF, Xiao Z,  Spatiotemporal delivery of nanoformulated liraglutide for cardiac regeneration after myocardial infarction  Int J Nanomedicine  2017  12:4835-4848 
    Sen Li, Haiqing Li, Zhize Yuan, Baoli Zhang, Anqing Chen, Mi Zhou, Jun Liu, Junfeng Cai, Zhe Wang, Xiaofeng Ye,  Off-pump coronary artery bypass surgery outcomes in patients with ischaemic left ventricular systolic dysfunction with or without detected viable myocardium  Interactive CardioVascular and Thoracic Surgery  2017  25:218–224 
    Zhize Yuan, Haiqing Li, Quan Qi, Wenhui Gong, Cheng Qian, Rong Dong, Yi Zang, Jia Li, Mi Zhou, Junfeng Cai, Zhe Wang, Anqing Chen, Xiaofeng Ye & Qiang Zhao  Plasma levels of growth differentiation factor-15 are associated with myocardial injury in patients undergoing off-pump coronary artery bypass grafting  Scientific Report  2016  1-9 
    Wenhui Gong*, Junfeng Cai*, Zhe Wang, Anqing Chen, Xiaofeng Ye, Haiqing Li,  Robot-assisted coronary artery bypass grafting improves shortterm outcomes compared with minimally invasive direct coronary artery bypass grafting  J Thorac Dis  2016  8(3):459-468 
    Wenhui Gong, Dong Lei, Sen Li, Peng Huang, Quan Qi, Yijun Sun, Yijie Zhang, Zhe Wang, Zhengwei You, Xiaofeng Ye,  Hybrid small-diameter vascular grafts: Anti-expansion effect of electrospun poly ε-caprolactone on heparin-coated decellularized matrices  Biomaterials  2016  76:359-370 
    Jianfeng Zhang, Anqing Chen,Yicheng Wu,  Placental Growth Factor Promotes Cardiac Muscle Repair via Enhanced Neovascularization  Cellular Physiology and Biochemistry  2015  36:947-955 
    Zhou J, Ye X, Wang Z, Liu J, Zhang B, Qiu J, Sun Y, Li H,  Development of decellularized aortic valvular conduit coated by heparin-SDF-1α multilayer  Ann Thorac Surg  2015  99(2):612-8 
    Gong W,  Extenuating symptoms is very important for malignant pericardial effusion.  J Thorac Dis  2015  7(4):E104  
    Dong-Xing Liu, Yu-Qing Zhang, Bo Hu, Jianfeng Zhang,  Association of AT1R polymorphism with hypertension risk: An update meta-analysis based on 28,952 subjects  Journal of the Renin-Angiotensin- Aldosterone System  2015  Journal of the Renin-Angiotensin- Aldosterone System 
    Xiang Hu, Hao-Zhe Wang, Jun Liu, An-Qin Chen, Xiao-Feng Ye,  A Novel Role of Sympathetic Activity in Regulating Mitral Valve Prolapse  Circulation Journal  2014  78: 1486 – 1493 
    Yang Z, Qiu J, Fang Y, Ying C, Shen W,  Subacute biventricular rupture with extracardiac left-to-right shunt after an inferior acute myocardial infarction  Ann Thorac Surg  2014  98(3):1090-1 
    Busheng Zhang, Jingxin Zhou, Haiqing Li, Zixiong Liu, Anqing Chen,  Comparison of graft patency between off-pump and on-pump coronary artery bypass grafting: An updated meta-analysis  Ann Thorac Surgery  2014  97:1335-42  
    Zhang B, Zhou M, Li C, Zhou J, Li H, Zhu D, Wang Z, Chen A,  MicroRNA-92a inhibition attenuates hypoxia/reoxygenation-induced myocardiocyte apoptosis by targeting Smad7  PLos One  2014  18;9(6)e100298 
    Xiaofeng Ye, Haozhe Wang, Jingxin Zhou, Haiqing Li, Jun Liu, Zhe Wang, Anqing Chen,  The Effect of Heparin-VEGF Multilayer on the Biocompatibility of Decellularized Aortic Valve with Platelet and Endothelial Progenitor Cells  PLOS ONE  2013  8(1): e54622 
    ,张瑞岩,王哲,杨震坤,张奇,沈卫峰  经主动脉途径植入主动脉支架瓣膜一例报道  上海交通大学学报医学版  2013  11：1552-1554 
    Li H, Liu J, Ye X, Zhang X, Wang Z, Chen A, Zhou M,  17β-Estradiol enhances the recruitment of bone marrow-derived endothelial progenitor cells into infarcted myocardium by inducing CXCR4 expression  Int J Cardiol  2013  162(2):100-6 
    邬祎程,  经导管主动脉瓣置入术治疗严重主动脉瓣狭窄  中华胸心血管外科杂志  2012  2：XX-XX 
    王肃,蔡俊锋,罗哲,顾立栩,王哲,  磁导航引导主动脉支架植入术的实验研究  中国临床医学  2012  2：XX-XX 
    Xiang Hu,, Xiaofeng Ye  Autonomic Regulation of Mechanical Properties in Porcine Mitral Valve Cusps  Arq Bras Cardiol  2012  98(4)321-328 
    Xiaofeng Ye, Xiang Hu, Haozhe Wang, Jun Liu,  Polyelectrolyte multilayer film on decellularized porcine aortic valve can reduce the adhesion of blood cells without affecting the growth of human circulating progenitor cells  Acta Biomaterialia  2012  8(3):1057-67 
    , Ye XF  Additive value of adult bone marrow-derived cell transplantation to conventional revascularization in chronic ischemic heart disease: a systemic review and meta-analysis  Expert Opinion on Biological Therapy  2011  11(12):1569-1579 
    , Ye X, Liu J, Chen H, Zhu D, Jin Z  Pulmonary thromboembolism in a patient with rheumatic mitral valve stenosis: a fortuitous association?  Ann Thorac Surg  2011  92(6):2263-6 
    Dan Zhu, Anqing Chen,  Surgical repair for isolated congenital double-orifice mitral valve  European Journal of Cardio-Thoracic Surgery  2011  39:268-270 
    Xiang Hu,  Systematic evaluation of the flexible and rigid annuloplasty ring after mitral valve repair for mitral regurgitation  European Journal of Cardio-thoracic Surgery  2011  40(2):480-7 
    Xiang Hu,  Skeletonized Internal Thoracic Artery Harvest Improves Prognosis in High-Risk Population After Coronary Artery Bypass Surgery for Good Quality Grafts  Ann Thorac Surg  2011  92:48–58 
    Dan Zhu,  Dynamic Normal Aortic Root Diameters: Implications for Aortic Root Reconstruction  Ann Thorac Surg  2011  91:485–90 
    Xiang Hu,  Systematic comparison of the effectiveness of radial artery and saphenous vein or right internal thoracic artery coronary bypass grafts in non-left anterior descending coronary arteries  J Zhejiang Univ Sci B  2011  12(4):273-279 
    Cai J, Luo Z, Gu L, Xu R,  The implementation of an integrated computer-assisted system for minimally invasive cardiac surgery  Int J Med Robot  2010  6(1):102-12 
    朱丹,王哲,陈安清,  缺血性心肌病非移植外科治疗远期效果  中华胸心血管外科杂志  2010  26（4）：224-226 
    ,朱丹,王哲,陈安清,刘俊  冠状动脉旁路移植术治疗6例儿童川崎病并发冠状动脉病变  中华胸心血管外科杂志  2010  26（5）：322-324 
    ,朱丹,王哲,陈安清,刘俊  冠状动脉旁路移植术治疗6例儿童川崎病并发冠状动脉病变  中华胸心血管外科杂志  2010  26（5）：322-324 
    陈安清,徐德民,魏来,王哲,夏利民,汪昊喆,  冠状动脉旁路移植术应用盐酸地尔硫卓的临床分析  中国临床医学  2009  16（4）：507-509 
    陈安清,徐德民,魏来,王哲,夏利民,汪昊喆,  冠状动脉旁路移植术应用盐酸地尔硫卓的临床分析  中国临床医学  2009  16（4）：507-509 
    孙晓宁,,陈安清,夏利民,周光华,王哲,徐德民  右胸小切口封堵缺乏边缘的Ⅱ孔型房间隔缺损  中华胸心血管外科杂志  2009  25（2）：93-95 
    朱丹,王哲,陈安清,夏利民,王春生,  合并心功能受损非缺血性二尖瓣反流的外科修复  中国临床医学  2009  16（5）：692-694 
    Ye Xiofeng,, Sun Xiaoning, Li H  Enhancement of Mesenchymal Stem Cell Attachment to Decellularized Porcine Aortic Valve Scaffold by In Vitro Coating with Antibody against CD90: A Preliminary Study on Antibody-Modified Tissue-Engineered Heart Valve  Tissue Engineering  2009  15:1-11 
    李海清,,孙晓宁,魏来,叶晓峰  生理性雌激素对骨髓源性内皮祖细胞迁移功能的影响  中国分子心脏病学杂志  2009  9（02）：79-83 
    , Sun Xiaoning, Chen Anqing, Xia Limin, Wang Zhe  Endoscopy- guided occlusion of secundum atrial defect permits use of smaller, cosmetically superior thoracotomy  Journal of Cardiac Surgery  2009  24:181-4 
    魏强,,魏来,夏利民,王春生  成人心肌干细胞的体外培养纯化与鉴定  中国临床医学  2009  16（02）：187-190 
    , Yongxin Sun, Limin Xia, Anqing Chen, Zhe Wang  Randomized Study of Mononuclear Bone Marrow Cells Transplantation in Patients with Coronary Surgery  Ann Torac Surg  2008  86：1833－1840 
    孙晓宁,,潘翠珍,陈安清,夏利民,周光华,王哲,徐德民  四叶式主动脉瓣畸形的诊断及外科治疗  中华胸心血管外科杂志  2008  24（3）：166-168 
    Zhu Dan,  Aortic valve annulus and sinus-tube joint diameters in normal adults of Chinese Han ethnic group  Chin Med J (Eng)  2008  21:1092-5 
    朱丹,夏利民,  左心室-降主动脉旁路移植术治疗复杂左室流出道狭窄1例  中华胸心血管外科杂志  2008  24（3）：165 
    夏利民,孙勇新,  内皮祖细胞灌注供心延长心脏移植物存活时间的实验研究  复旦学报(医学版)  2008  35(6)：873~877 
    王哲,夏利民,陈安清,徐德民,杨成,  扩大Morrow术治疗肥厚性梗阻型心肌病  中华胸心血管外科杂志  2008  24（3）：169-170 
    叶晓峰,,孙晓宁  生物素化去细胞猪主动脉瓣构建组织工程心脏瓣膜研究  中华实验外科杂志  2008  25（1）：80-82 
    ,王春生,朱丹,陈安清,夏利民,王哲  保留瓣叶的主动脉根部置换术近期疗效  中华胸心血管外科杂志  2008  24（1）：15-17 
    朱丹,陈安清,夏利民,王哲,  复杂性二尖瓣反流的外科修复  中华胸心血管外科杂志  2008  24（2）：76-79 
    , Liu Zhixiong, Wang Zhe, Yang Chen, Liu Jun,Lu Jun  Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cell on pulmonary hypertension  Ann Thorac Surg  2007  84:544-52 
    Wanyin Zhai, Jiang Chang, Kaili Lin, Junyin Wang,, Xiaoning Sun  Crosslinking of decellularized porcine heart valve by procyanidins for preparation of artificial biological valve  Biomaterials  2006  27: 3684-3690 
    Yao Liang Tang,, Xinyu Qin, et al  Paracrine Action Enhances the Effects of Autologous Mesenchymal Stem Cell Transplantation on Vascular Regeneration in Rat Model of Myocardial Infarction  Ann Thorac Surg  2005  80:229 –37 
    Tang YL,, Zhang YC, Cheng L, Liu M, Shi J, Yang YZ, Pan C, Ge J, Phillips MI  Autologous mesenchymal stem cell transplantation induce VEGF and neovascularization in ischemic myocardium  Regul Pept  2004  15;117(1):3-10