• 基本信息
    导师姓名: 戎伟芳 学科代码: 100100
    性别: 学科名称: 基础医学
    培养单位: 基础医学院 三级学科
    导师类型: 博士生导师 专业领域名称:
    联系方式: weifangrong@hotmail.com; weifangrong@shsmu.edu.cn 上海市重庆南路280号5号楼601室 专业领域代码:
    邮编: 200025 邮箱地址: weifangrong@hotmail.com
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    Journal of Physiology(London)编委、《生理学报》编委
    中国生理学会理事;中国生理学会消化与营养专业委员会副主任委员;上海市生理科学会副理事长
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    81873728延髓腹内侧部G蛋白偶联型雌激素受体反向调控痛痒觉的环路与分子机制解析国家自然科学基金面上项目 2019-01~2022-12 56万元  课题负责人
    81570493肠嗜铬细胞HCN2离子通道对肠道免疫炎症反应的正反馈调节作用研究国家自然科学基金面上项目 2016-01~2019-12 57万元  课题负责人
    2014CB910303重要新型膜离子通道的生理和药理功能国家重大科学研究计划项目 2014-08~2019-08 120万元  课题参与人
    GZ919嘌呤信号在针刺镇痛中的作用中德科学中心 2013-10~2016-09 70万元  课题负责人
    81270464肠道感觉神经HCN通道表达和功能变化的天然免疫机制与内脏痛敏的发生及转归国家自然科学基金面上项目 2013-01~2016-12 85万元  课题负责人
    31171066雌激素经G蛋白耦联型受体GPR30介导中枢性内脏痛敏机制研究国家自然科学基金 2012-01~2015-12 64万元  课题负责人
    10ZZ69酸敏感离子通道在摄食调节和肥胖中的作用上海市教委科研创新重点 2010-01~2012-12 15万元  课题负责人
    30770797硫化氢对颈动脉体化学感受器功能的影响及其分子机制国家自然基金委,面上项目 2008-01~2010-12 42万元  课题负责人
    05PJ14053肠易激素综合症的细胞和分子机制研究上海市科委,浦江人才 2005-12~2007-09 20万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Wu Y, Wang Y, Wang J, Fan Q, Zhu J, Yang L,  TLR4 mediates upregulation and sensitization of TRPV1 in primary afferent neurons in 2,4,6-trinitrobenzene sulfate-induced colitis  Molecular Pain  2019  15 
    Luo P, Shao J, Jiao Y, Yu W,  CC chemokine ligand 2 (CCL2) enhances TTX-sensitive sodium channel activity of primary afferent neurons in the complete Freud adjuvant-induced inflammatory pain model  Acta Biochim Biophys Sin  2018  50(12):1219-1226 
    Han H, Liang X, Wang J, Zhao Q, Yang M, Rong W,  Cannabinoid receptor 1 contributes to sprouted innervation in endometrial ectopic growth through mitogen-activated protein kinase activation.  Brain Res.  2017  1663:132-140 
    Gao P, Ding X, Khan TM,, Franke H, Illes P.  P2X7 receptor-sensitivity of astrocytes and neurons in the substantia gelatinosa of organotypic spinal cord slices of the mouse depends on the length of the culture period.  Neuroscience  2017  349:195-207 
    Meng Y, Dong L, Sun B, Luo P, Zhang G,  In Vitro Characterization of the Electrophysiological Properties of Colonic Afferent Fibers in Rats.  J Vis Exp  2017  doi: 10.3791/56090 
    Gao P, Ding XW, Dong L, Luo P, Zhang GH,  Expression of aromatase in the rostral ventromedial medulla and its role in regulation of visceral pain  CNS Neurosci Ther  2017  doi: 10.1111/cns.12769 
    Luo P, Wu MM, Gao P, Gao T, Dong L, Ding XW, Meng YQ, Qian JH, Zhang GH,  Stress-related arterial hypertension in Gper-deficient rats.  Sheng Li Xue Bao  2017  69(5):532-540 
    Rozmer K, Gao P, Araújo MG, Khan MT, Liu J,, Tang Y, Franke H, Krügel U, Fernandes MJ, Illes P.  Pilocarpine-Induced Status Epilepticus Increases the Sensitivity of P2X7 and P2Y1 Receptors to Nucleotides at Neural Progenitor Cells of the Juvenile Rodent Hippocampus  Cereb Cortex  2016  pii: bhw178. 
    Dong L, Liang X, Sun B, Ding X, Han H, Zhang G,  Impairments of the primary afferent nerves in a rat model of diabetic visceral hyposensitivity.  Mol Pain  2015  11:74. 
    Jiao Y, Li Q, Sun B, Zhang G,  Hydrogen sulfide activates the carotid body chemoreceptors in cat, rabbit and rat ex vivo preparations  Respir Physiol Neurobiol  2015  208:15-20 
    Ni YY, Chen Y, Lu SY, Sun BY, Wang F, Wu XL, Dang SY, Zhang GH, Zhang HX, Kuang Y, Fei J, Gu MM,, Wang ZG#.  Deletion of Gpr128 results in weight loss and increased intestinal contraction frequency.  World J Gastroenterol  2014  20(2): 498-508. 
    Zhi L, Dong L, Kong D, Sun B, Sun Q, Grundy D, Zhang G,  Curcumin acts via transient receptor potential vanilloid-1 receptors to inhibit gut nociception and reverses visceral hyperalgesia.  Neurogastroenterology & Motility  2013  25(6):e429-40 
    Huang X, Sun J,, Zhao T, Li DH, Ding X, Wu LY, Wu K, Schachner M, Xiao ZC, Zhu LL, Fan M.  Loss of cell adhesion molecule CHL1 improves homeostatic adaptation and survival in hypoxic stress  Cell Death Dis.  2013  4:e768. 
    Rasmussen BA, Breen DM, Luo P, Cheung GWC, Yang CS, Sun B, Kokorovic A,  Activation of cAMP-dependent protein kinase in the duodenum triggers vagal afferent firing and lowers glucose production in rats  Gastroenterology  2012  142(4):834-843 
    Wang Y, Sun B, Li Q, Dong L, Zhang GH,  HCN channel subtypes differentially modulate mechanosensitivity of extrinsic afferents of murine small intestine  World J Gastroenterol  2012  18: 523-531 
    Han H, Lee K,, Zhang GH  Different roles of Peripheral Mitogen-activated Protein kinases in carrageenan-induced arthritic pain and arthritis in rats  Anesthesia & Analgesia  2012  115(5):1221-7 
    Zhou Y, Sun B, Li Q, Luo P, Dong L,  Sensitivity of bronchopulmonary receptors to cold and heat mediated by transient receptor potential cation channel subtypes in an ex vivo rat lung preparation.   Respir Physiol Neurobiol.  2011  177(3):327-32 
    , Kimura H, Grundy D.  The neurophysiology of hydrogen sulfide  Inflamm Allergy Drug Targets  2011  10(2):109-17 
    Sun B, Li Q, Dong L,  Ion channel and receptor mechanisms of bladder afferent nerve sensitivity.   Auton Neurosci.  2010  153(1-2):26-32. 
    , Zhu J  Emerging excellence in neurogastroenterology and motility research in mainland China  Neurogastroenterol Motil  2010  22(9):949-952 
    Li Q, Sun B, Wang X, Jin Z, Zhou Y, Dong L, Jiang LH,  A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels.  Antioxid Redox Signal  2010  12(10):1179-89. 
    Hu Y, Dong L, Sun B, Guillon MA, Burbach LR, Nunn PA, Liu X, Vilenski O, Ford AP, Zhong Y,  The role of metabotropic glutamate receptor mGlu5 in control of micturition and bladder nociception.  Neurosci Lett  2009  450(1):12-7 
      Sensing the fullness of the bladder.  J Physiol  2009  587(Pt 14):3417-8. 
    , Keating C, Sun B, Dong L, Grundy D  Purinergic contribution to small intestinal afferent hypersensitivity in a murine model of postinfectious bowel disease.  Neurogastroenterol Motil.  2009  21(6):665-71 
    Daly D,, Chess-Williams R, Chapple C, Grundy D.  Bladder afferent sensitivity in wild-type and TRPV1 knockout mice.  J Physiol  2007  583(Pt 2):663-74. 
    , Winchester WJ, Grundy D  Spontaneous hypersensitivity in mesenteric afferent nerves of mice deficient in the sst2 subtype of somatostatin receptor.   J Physiol  2007  581(Pt 2):779-86 
    , Burnstock G.  Activation of ureter nociceptors by exogenous and endogenous ATP in guinea pig.  Neuropharmacology  2004  47(7):1093-101 
    , Hillsley K, Davis JB, Hicks G, Winchester WJ, Grundy D.  Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice.  J Physiol.  2004  560(Pt 3):867-81. 
    Wynn G,, Xiang Z, Burnstock G.  Purinergic mechanisms contribute to mechanosensory transduction in the rat colorectum.   Gastroenterology  2003  125(5):1398-409 
    , Gourine AV, Cockayne DA, Xiang Z, Ford AP, Spyer KM, Burnstock G  Pivotal role of nucleotide P2X2 receptor subunit of the ATP-gated ion channel mediating ventilatory responses to hypoxia.   J Neurosci.  2003  23(36):11315-21. 
    , Spyer KM, Burnstock G.  Activation and sensitisation of low and high threshold afferent fibres mediated by P2X receptors in the mouse urinary bladder.  J Physiol  2002  541(Pt 2):591-600. 
    Vlaskovska M, Kasakov L,, Bodin P, Bardini M, Cockayne DA, Ford AP, Burnstock G.   P2X3 knock-out mice reveal a major sensory role for urothelially released ATP.  J Neurosci.  2001  21(15):5670-7. 
    , Burnstock G, Spyer KM.  P2X purinoceptor-mediated excitation of trigeminal lingual nerve terminals in an in vitro intra-arterially perfused rat tongue preparation.  J Physiol  2000  524 Pt 3:891-902. 
    , Wang W, Yuan W, Chen Y  Rapid effects of corticosterone on cardiovascular neurons in the rostral ventrolateral medulla of rats.   Brain Res  1999  815(1):51-9.