- 基本信息
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导师姓名：
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周慧芳
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学科代码：
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100212
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性别：
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女
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学科名称：
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眼科学
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培养单位：
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附属第九人民医院
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三级学科
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导师类型：
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博士生导师
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专业领域名称：
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眼科学 专业学位
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联系方式：
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021-23271699-5586
fangzzfang@163.com
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专业领域代码：
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105116
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邮编：
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200011
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邮箱地址：
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fangzzfang@163.com
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- 研究方向 (点击浏览详细信息)
- 社会任职
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中华医学会医师培训工程《中华眼科学操作技术全集》编辑委员会委员
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上海市女医师协会医学科普专委会副主委
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中国医师协会眼科医师分会青年委员
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上海交通大学女教师女医师学术交流协会副会长
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美国眼整形外科学会(ASOPRS)会员
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海峡两岸医药卫生交流协会眼科学专业委员会甲状腺相关性眼病学组副组长
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中华医学会眼科学分会眼免疫学组委员
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亚太眼整形重建学会(APSOPRS)理事
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中国医疗保健国际交流促进会视觉健康分会青年委员
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上海医学会眼科学分会青年委员
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中国医师协会眼整形眼眶病学组委员
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中国女医师协会眼科专委会青年委员副主委
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- 科研项目
| 82271122 | Trp代谢物激活AhR促进甲状腺相关眼病炎症反应的机制研究 | 国家自然科学基金面上项目 |
2023-01~2026-12
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56万元
| 课题负责人 |
| 82071003 | Slit2调控IL-6/STAT3通路抑制甲状腺相关眼病炎症反应的机理研究 | 国家自然科学基金面上项目 |
2021-01~2024-12
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55万元
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| SHDC2020CR3051B | 导航手术机器人在眼眶外侧壁手术中的应用研究 | 促进市级医院临床技能与临床创新能力三年行动计划项目 |
2020-10~2022-09
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100万元
| 课题负责人 |
| 19410761100 | 基于三维模型人工智能分析的眼眶病筛查方法研究 | 上海市“科技创新行动计划”港澳台科技合作项目 |
2019-07~2022-06
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40万元
| 课题负责人 |
| ZH2018ZDA12 | 用于提高诊疗效能的数字化眼眶医生全链条培养系统研发 | 上海交通大学“转化医学交叉研究基金”重点A类 |
2019-01~2021-12
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100万元
| 课题负责人 |
| / | 眼肿瘤眼眶病协同创新团队激励项目 | 上海市教委“高水平地方高校建设创新团队” |
2019-01~2021-12
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100万元
| 课题负责人 |
| 20152228 | 甲状腺相关眼病手术治疗新技术及其应用研究 | 上海交通大学医学院高峰高原计划—“研究型医师”继续资助项目 |
2018-10~2021-09
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100万元
| 课题负责人 |
| 81770960 | Gremlin-1基因活化支架负载BMSCs促进眼眶骨再生及其机制研究 | 国家自然科学基金面上项目 |
2018-01~2021-12
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56万元
| 课题负责人 |
| 8171101030 | 易感和致病基因在甲状腺相关眼病免疫病理和疾病预测中的作用机制 | 国家自然科学基金面上项目（国际地区合作） |
2018-01~2021-12
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85万元
| 课题负责人 |
| TM201718 | 基于导航的眼眶外科机器人关键技术研究 | 上海交通大学医学院转化医学协同创新中心合作研究项目 |
2017-12~2019-11
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15万元
| 课题负责人 |
| / | 甲状腺相关眼病MDT诊疗团队 | 上海交通大学医学院附属九院临床研究型MDT项目 |
2017-10~2020-09
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150万元
| 课题负责人 |
| / | 甲氨蝶呤对比放疗治疗中重度活动期甲状腺相关眼病多中心、前瞻性、随机对照研究 | 上海交通大学医学院多中心临床研究项目 |
2016-01~2018-12
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150万元
| 课题负责人 |
| / | 甲状腺相关眼病手术治疗新技术及其应用研究 | 上海交通大学医学院高峰高原计划—“研究型医师” |
2015-10~2018-09
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100万元
| 课题负责人 |
| YG2014MS03 | 可控释壳聚糖原位凝胶结合BMSCs微球改善眼眶成骨微环境的研究 | 上海交通大学“医工交叉基金”面上项目 |
2015-01~2017-12
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15万元
| 课题负责人 |
| 13JC1403800 | 可控释水凝胶结合BMSCs微球改善眼眶成骨微环境的研究 | 上海市基础研究重点项目 |
2013-09~2016-08
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40万元
| 课题负责人 |
| XYQ2011053 | 富集干细胞技术促进眼眶骨再生的基础及临床研究 | 新一轮上海市卫生系统优秀青年人才培养计划 |
2011-11~2014-10
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60万元
| 课题负责人 |
| 81000404 | 干细胞快速浓缩分离并高效融合生物材料修复眼眶骨缺损 | 国家自然基金 |
2011-01~2013-12
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21万元
| 课题负责人 |
- 学术论文
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Liu J, Liu Z, Pang Y,
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The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases
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J Nanobiotechnology
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2022
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20(1):127
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Huang Y, Wu Y, Zhang S, Lu Y, Wang Y, Liu X, Zhong S, Wang Y, Li Y, Sun J, Fang S,
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Immunophenotype of lacrimal glands in Graves orbitopathy: Implications for the pathogenesis of Th1 and Th17 immunity
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Thyroid
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2022
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32(8):949-961
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Wang Y, Sun J, Liu X, Li Y, Fan X,
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Robot-Assisted Orbital Fat Decompression Surgery: First in Human
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Transl Vis Sci Technol
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2022
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11(5):8
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Li J, Yang S, Liu Z, Wang G, He P, Wei W, Yang M, Deng Y, Gu P, Xie X, Kang Z*, Ding G*,, Fan X*
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Imaging Cellular Aerobic Glycolysis Using Carbon Dots for Early Warning of Tumorigenesis
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Adv Mater
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2021
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33(1):e2005096
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Lu Y, Wu Y, Huang Y, Fang S, Li Y, Sun J,
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Immunological Features of Paranasal Sinus Mucosa in Patients with Graves' Orbitopathy
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Front Endocrinol
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2021
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11:621321
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Li L, Song X, Guo Y, Liu Y, Sun R, Zou H,, Fan X
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Deep Convolutional Neural Networks for Automatic Detection of Orbital Blowout Fractures
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J Craniofac Surg
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2020
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31(2):400-403
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Li J, Xue Y, Tian J, Liu Z, Zhuang A, Gu P,, Zhang W, Fan X
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Fluorinated-functionalized hyaluronic acid nanoparticles for enhanced photodynamic therapy of ocular choroidal melanoma by ameliorating hypoxia
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Carbohydr Polym
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2020
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237:116119
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Fang S, Zhang S, Huang Y, Wu Y, Lu Y, Zhong S, Liu X, Wang Y, Li Y, Sun J, Gu P,, Fan X
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Evidence for Associations Between Th1/Th17 "Hybrid" Phenotype and Altered Lipometabolism in Very Severe Graves Orbitopathy
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J Clin Endocrinol Metab
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2020
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105(6):dgaa124
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Xue Y, Li J, Yang G, Liu Z,, Zhang W
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Multistep Consolidated Phototherapy Mediated by a NIR-Activated Photosensitizer
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ACS Appl Mater Interfaces
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2019
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11(37):33628-33636
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Fang S, Huang Y, Wang N, Zhang S, Zhong S, Li Y, Sun J, Liu X, Wang Y, Gu P, Li B,, Fan X
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Insights Into Local Orbital Immunity: Evidence for the Involvement of the Th17 Cell Pathway in Thyroid-Associated Ophthalmopathy
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J Clin Endocrinol Metab
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2019
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104(5):1697-1711
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Huang Y, Fang S, Li D,, Li B, Fan X
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The involvement of T cell pathogenesis in thyroid-associated ophthalmopathy
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Eye (Lond)
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2019
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33(2):176-182.
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Fang S, Huang Y, Liu X, Zhong S, Wang N, Zhao B, Li Y, Sun J, Wang Y, Zhang S, Gu P,, Li B, Fan X
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Interaction Between CCR6+ Th17 Cells and CD34+ Fibrocytes Promotes Inflammation: Implications in Graves' Orbitopathy in Chinese Population
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Invest Ophthalmol Vis Sci
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2018
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59(6):2604-2614
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Wang Y, Zhang S, Zhang Y, Liu X, Gu H, Zhong S, Huang Y, Fang S, Sun J,, Fan X*
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A single-center retrospective study of factors related to the effects of intravenous glucocorticoid therapy in moderate-to-severe and active thyroid-associated ophthalmopathy.
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BMC Endocr Disord
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2018
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18(1):13
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Li J, Yang S, Deng Y, Chai P, Yang Y, He X, Xie X, Kang Z*, Ding G*,, Fan X*.
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Emancipating target-functionalized carbon dots from autophagy vesicles for a novel visualized tumour therapy
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Adv Funct Mater
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2018
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Epub 2018 May 29
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Sun J, Liu X, Zhang Y, Huang Y, Zhong S, Fang S, Zhuang A, Li Y,, Fan X*.
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Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction
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Med Sci Monit
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2018
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24:2728-2734
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Zhang S, Wang Y, Zhong S, Liu X, Huang Y, Fang S, Zhuang A, Li Y, Sun J,, Fan X*
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Orbital radiotherapy plus three-wall orbital decompression in a patient with rare ocular manifestations of thyroid eye disease: case report.
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BMC Endocr Disord
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2018
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18(1):7
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Fang S, Huang Y, Zhong S, Li Y, Zhang Y, Li Y, Sun J, Liu X, Wang Y, Zhang S, Xu T, Sun X, Gu P, Li D,, Li B, Fan X.
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Regulation of orbital fibrosis and adipogenesis by pathogenic Th17 cells in Graves' orbitopathy.
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J Clin Endocrinol Metab
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2017
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102(11):4273-4283
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Wang Y,,Fan X*
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The effect of orbital radiation therapy on thyroid-associated orbitopathy complicated with dysthyroid optic neuropathy.
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Front Med.
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2017
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11(3):359-364
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Fang S,Huang Y,Wang S,Zhang Y,Luo X,Liu L,Zhong S,Liu X, Li D,Liang R,Miranda P,Gu P,,Fan X,Li B
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IL-17A exacerbates fibrosis by promoting the proinflammatory and profibrotic function of orbital fibroblasts in TAO
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J Clin Endocrinol Metab
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2016
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[Epub ahead of print]
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Zhang W,Zhuang A,Gu P,,Fan X*
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A review of the three-dimensional cell culture technique: Approaches, advantages and applications
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Curr Stem Cell Res Ther
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2016
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11(4):370-380
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Xie Q*,Wang Z*,,Yu Z,Huang Y,Sun H,Bi X,Wang Y, Shi W,Gu P,Fan X
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The role of miR-135-modified adipose-derived mesenchymal stem cells in bone regeneration
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Biomaterials
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2015
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75:279-294
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Ji Y,Ye F,,Xie Q,Ge S,Fan X*
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Bony orbital maldevelopment after enucleation
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J Anat
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2015
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227(5):647-53
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Deng Y*,,Gu P,Fan X
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Repair of canine medial orbital bone defects with miR-31-modified bone marrow mesenchymal stem cells
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Invest Ophthalmol Vis Sci
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2014
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55(9):6016-6023
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,Lu Q,Guo Q,Chae J,Fan X,Elisseeff JH,Grant MP
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Vitrified collagen-based conjunctival equivalent for ocular surface reconstruction
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Biomaterials
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2014
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35(26):7398-406
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Deng Y*,,Yan C,Wang Y,Xiao C,Gu P,Fan X
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In vitro osteogenic induction of BMSCs with encapsulated gene modified BMSCs and in vivo implantation for orbital bone repair
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Tissue Eng Part A
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2014
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20(13-14):2019-29
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Deng Y*,,Zou D,Xie Q,Bi X,Gu P,Fan X.
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The role of miR-31-modified adipose tissue-derived stem cells in repairing rat critical-sized calvarial defects
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Biomaterials
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2013
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34(28):6717-28
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,Deng Y,Bi X,Xiao C,Wang Y,Sun J,Gu P,Fan X
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Orbital wall repair in canines with beta-tricalcium phosphate and induced bone marrow stromal cells
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J Biomed Mater Res B Appl Biomater
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2013
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101(8):1340-1349
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Sun J*,,Deng Y,Zhang Y,Gu P,Ge S,Fan X
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Conditioned medium from bone marrow mesenchymal stem cells transiently retards osteoblast differentiation by downregulating runx2
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Cells Tissues Organs
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2012
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196(6):510-22
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Xiao C*,,Liu G,Zhang P,Fu Y,Gu P,Hou H,Tang T,Fan X
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Bone marrow stromal cells with a combined expression of BMP-2 and VEGF-165 enhanced bone regeneration
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Biomed Mater
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2011
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6(1):015013
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,Xiao C,Wang Y,Bi X,Ge S,Fan X
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In vivo efficacy of bone marrow stromal cells coated with Beta-tricalcium phosphate for the reconstruction of orbital defects in canines
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Invest Ophthalmol Vis Sci
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2011
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52(3):1735-41
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Xiao C*,,Ge S,Tang T,Hou H,Luo M,Fan X
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Repair of orbital wall defects using biocoral scaffolds combined with bone marrow stem cells enhanced by human bone morphogenetic protein-2 in a canine model
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Int J Mol Med
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2010
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26(4):517-25
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Xiao C*,,Ge S,Tang T,Hou H,Luo M,Fan X
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Repair of orbital wall defects using biocoral scaffolds combined with bone marrow stem cells enhanced by human bone morphogenetic protein-2 in a canine model
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Int J Mol Med
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2010
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26(4):517-25
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,Fan X, Xiao C
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Direct orbital manometry in normal and fractured orbits of Chinese patients
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J Oral Maxillofac Surg
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2007
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65 (11):2282-2287
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