• 基本信息
    导师姓名: 肖泽宇 专业代码: 100700
    性别: 专业名称: 药学
    培养单位: 基础医学院 三级学科/
    专业领域:
    导师类型: 博士生导师 专业学位导师:
    联系方式: http://xiao.shsmu.edu.cn
    邮箱地址: xiaozeyu@shsmu.edu.cn 邮编:
  • 研究方向 (点击浏览详细信息)
  • 社会任职
     
    美中医药协会会员
    美国癌症研究协会会员
    中国化学会会员
    Bridge Medicine 编辑
    美国化学会会员
  • 科研项目
    项目编号项目名称课题来源起止年月批准经费承担职责
    21874092拉曼纳米探针用于活性氧异常疾病的医学分析研究国家自然科学基金 2019-01~2022-12 64万元  课题负责人
    81741014SP-A核酸适体拉曼纳米探针用于胎肺发育及异常的产前诊断研究国家自然科学基金 2018-01~2018-12 20万元  课题负责人
    31671003核酸识体纳米药物在组织脏器的三维精准分布及靶向识别国家自然科学基金 2017-01~2020-12 62万元  课题负责人
    81471779DNA自主装纳米诊疗系统:构建及术中成像介导下前列腺癌细胞清除的问题研究国家自然科学基金 2015-01~2018-12 73万元  课题负责人
    2014上海市东方学者特聘教授上海市教委 2015-01~2017-12 100万元  课题负责人
    2014中组部青年千人计划中组部 2015-01~2019-12 200万元  课题负责人
    2014课题启动经费上海交大医学院 2014-08~2019-12 200万元  课题负责人
  • 学术论文
    作者论文标题期刊名出版年卷期页码
    Qiu Y, Zhang Y, Li M, Chen G, Fan C, Cui K, Wan J, Han A, Ye J*,  Intraoperative detection and eradication of residual microtumors with gap-enhanced Raman tags.  ACS Nano  2018  in press 
    Li M, Qiu Y, Fan C, Cui K, Zhang Y,  Design of SERS nanoprobes for Raman imaging: materials, critical factors and architectures.  Acta Pharm Sin B.  2018  8(3):381-389 
    Zhang Y, Qiu Y, Lin L, Gu H,, Ye J*  Ultraphotostable Mesoporous Silica-Coated Gap-Enhanced Raman Tags (GERTs) for High-Speed Bioimaging.  ACS Appl Mater Interfaces  2017  9(4):3995-4005 
    Qi Q, Lu L, Li H, Yuan Z, Chen GX, Lin M, Ruan Z, Ye X*,, Zhao Q*   Spatiotemporal delivery of nanoformulated liraglutide for cardiac regeneration after myocardial infarction.  Int J Nanomedicine  2017  12:4835-4848 
    Lu L, Chen G, Qiu Y, Li M, Liu D, Hu D, Gu X,  Nanoparticle-based oral delivery systems for colon targeting: principles and design strategies.  Sci Bull  2016  61(9):670-681 
      CuS Nanoparticles: clinically favorable materials for photothermal therapy  Nanomedicine  2014  9(3):373-5 
    Wu J, Kamaly N, Shi J, Zhao L,, Hollett G, John R, Ray S, Xu X, Zhang X, Kantoff PW, Farokhzad OC  Development of multinuclear polymeric nanoparticles as robust protein nanocarriers  Angew Chem Int Ed Engl  2014  53(34):8975-9 
    , Farokhzad OC  Aptamer-functionalized nanoparticles for medical applications: challenges and opportunities  ACS Nano  2012  6(5):3670-3676 
    , Ji C, Shi J, Pridgen E, Frieder J, Wu J, Farokhzad OC  DNA self-assembly of targeted near infrared-responsive gold nanoparticles for cancer thermo-chemotherapy  Angew Chem Int Ed Engl  2012  51(47):11853-11857 
    , Levy-Nissenbaum E, Alex F, Luptak A, Teply B, Chan J, Shi J, Diggar E, Cheng J, Langer R, et al.  Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection  ACS Nano  2012  6 (1):696-704 
    Kamaly N,,Valencia PM, Radovic-Moreno AF, Farokhzad OC  Targeted polymeric therapeutic nanoparticles: design, development and clinical translation  Chem Soc Rev  2012  41(7):2971-3010 
    Shi J,, Kamaly N, Farokhzad OC  Self-assembled Targeted Nanoparticles: Evolution of Technologies and Bench to Bedside Translation  Acc Chem Res  2011  44(10):1123-34 
    Shi J,, Votruba AR, Viols C, Farokhzad OC  Differently Charged Hollow Core/shell Lipid-polymer-lipid Hybrid Nanoparticles for Small Interfering RNA Delivery  Angew Chem Int Ed Engl  2011  50(31):7027-7031 
    Gao W,, Radovic-Moreno A, Shi J, Langer R, Farokhzad OC  Progress in siRNA Delivery: A Multifunctional Approach by Polymeric Nanoparticles  Methods in Mol Biol  2010  629(1):53-67 
    Zhang W, Jiang Y, Wang Q, Ma X,, Zuo W, Fang X, Chen Y  Single Molecule Imaging Reveals Transforming Growth Factor-β-induced Type II Receptor Dimerization  Proc Natl Acad Sci U S A  2009  106(37):15679-15683 
    Liu Q, Chen B, Wang Q, Shi X,, Lin J, Fang X  Carbon Nanotubes as Molecular Tansporters for Walled Plant Cells  Nano Lett  2009  9(3):1007-1010 
    , Shangguan D, Cao ZC, Fang X, Tan W  Cell-specific Internalization Study of an Aptamer from Whole Cell Selection  Chemistry  2008  14(6):1769-1775 
    Yang R, Jin J, Chen Y, Shao N, Kang H,, Tang Z, Wu Y, Zhu Z, Tan W.  Identification of Liver Cancer-Carbon Nanotube-Quenched Fluorescent Oligonucleotides: Probes that Fluoresce upon Hybridization  J.Am.Chem.Soc  2008  130(26):8351–8358 
    , Zhang W, Yang Y, Xu L, Fang X  Single-molecule diffusion study of activated EGFR implicates its endocytic pathway  Biochem Biophys Res Commun  2008  369(2):730-734 
    , Ma X, Jiang Y, Liao J, Yue J, Fang X  Single-Molecule Study of Lateral Mobility of Epidermal Growth Factor Receptor 2/HER2 on Activation  J Phys Chem B  2008  112(13):4140-4145 
    Shangguan D, Meng L, Cao Z,, Fang X, Li Y, Cardona D, Witek RP, Liu C, Tan W.  Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells  Anal Chem  2008  80(3):721-728 
    Shangguan D, Tang Z, Mallikaratchy P,, Tan W  Optimization and Modifications of Aptamers Selected from Live Cancer Cell Lines  Chembiochem  2007  8(6):603-606 
    Ma X, Wang Q, Jiang Y,, Fang X, Chen Y  Optimization and Modifications of Lateral Diffusion of TGF-? Type I Receptor Studied by Single-Molecule Imaging  Biochem Biophys Res Commun  2007  356(1):67–71 
    Xu W,, Zhang T  Mechanical Properties of Silicone Elastomer on Temperature in Biomedical Application  Materials Letters  2005  59(17):2153-2155